JP2016503293A5 - - Google Patents

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Publication number
JP2016503293A5
JP2016503293A5 JP2015540154A JP2015540154A JP2016503293A5 JP 2016503293 A5 JP2016503293 A5 JP 2016503293A5 JP 2015540154 A JP2015540154 A JP 2015540154A JP 2015540154 A JP2015540154 A JP 2015540154A JP 2016503293 A5 JP2016503293 A5 JP 2016503293A5
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JP
Japan
Prior art keywords
seq
antibody
composition
cdr
binding member
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JP2015540154A
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English (en)
Japanese (ja)
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JP6333271B2 (ja
JP2016503293A (ja
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Priority claimed from PCT/EP2013/073009 external-priority patent/WO2014068132A1/en
Publication of JP2016503293A publication Critical patent/JP2016503293A/ja
Publication of JP2016503293A5 publication Critical patent/JP2016503293A5/ja
Application granted granted Critical
Publication of JP6333271B2 publication Critical patent/JP6333271B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2015540154A 2012-11-05 2013-11-05 IL−1βへの結合メンバー Expired - Fee Related JP6333271B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261722532P 2012-11-05 2012-11-05
US61/722,532 2012-11-05
EP12007503 2012-11-05
EP12007503.1 2012-11-05
PCT/EP2013/073009 WO2014068132A1 (en) 2012-11-05 2013-11-05 Binding members to il-1 beta

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018083160A Division JP6779252B2 (ja) 2012-11-05 2018-04-24 IL−1βへの結合メンバー

Publications (3)

Publication Number Publication Date
JP2016503293A JP2016503293A (ja) 2016-02-04
JP2016503293A5 true JP2016503293A5 (enExample) 2016-12-08
JP6333271B2 JP6333271B2 (ja) 2018-06-06

Family

ID=47146146

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015540154A Expired - Fee Related JP6333271B2 (ja) 2012-11-05 2013-11-05 IL−1βへの結合メンバー
JP2018083160A Expired - Fee Related JP6779252B2 (ja) 2012-11-05 2018-04-24 IL−1βへの結合メンバー

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2018083160A Expired - Fee Related JP6779252B2 (ja) 2012-11-05 2018-04-24 IL−1βへの結合メンバー

Country Status (11)

Country Link
US (5) US9404930B2 (enExample)
EP (2) EP2914287B1 (enExample)
JP (2) JP6333271B2 (enExample)
KR (1) KR102345999B1 (enExample)
CN (1) CN104870015B (enExample)
BR (1) BR112015009892B1 (enExample)
CA (1) CA2888583C (enExample)
MX (1) MX374817B (enExample)
PL (1) PL2914287T3 (enExample)
RU (1) RU2711118C2 (enExample)
WO (2) WO2014068132A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014068132A1 (en) * 2012-11-05 2014-05-08 Delenex Therapeutics Ag Binding members to il-1 beta
EP3186390B1 (en) 2014-08-29 2019-03-27 Pioneer Hi-Bred International, Inc. Methods and devices involving oil matrices
US9078427B1 (en) 2014-08-29 2015-07-14 Pioneer Hi Bred International Inc Method of storing plant embryos
JP6202652B1 (ja) * 2016-12-19 2017-09-27 株式会社ヘルスケアシステムズ 抗エクオール抗体組成物及びその利用
CN107362351B (zh) * 2017-09-04 2020-11-10 上海市儿童医院 Il-36r的拮抗剂在制备镇痛药物中的应用
CN110818793A (zh) 2018-08-14 2020-02-21 中山康方生物医药有限公司 抗IL-1β的抗体、其药物组合物及其用途
WO2020176210A1 (en) 2019-02-28 2020-09-03 Exxonmobil Chemical Patents Inc. Catalyst compositions and precursors, processes for making the same and syngas conversion processes
TWI793503B (zh) 2020-01-20 2023-02-21 美商美國禮來大藥廠 抗IL-1β抗體
TW202233237A (zh) 2020-11-18 2022-09-01 瑞士商諾華公司 用於在治療nlrc4-gof炎性體病變中使用的雙特異性抗體
US20240084039A1 (en) * 2020-12-23 2024-03-14 Numab Therapeutics AG Antibody variable domains and antibodies having decreased immunogenicity
WO2022136693A1 (en) * 2020-12-23 2022-06-30 Numab Therapeutics AG Antibody variable domains and antibodies having decreased immunogenicity
CN113908589B (zh) * 2021-10-08 2022-09-27 天津工业大学 一种表面印迹抗体的疏水电荷诱导模式膜层析介质及其制备方法
CN116410331B (zh) * 2021-12-31 2024-01-30 合源生物科技(天津)有限公司 靶向cs1的嵌合抗原受体、靶向bcma/cs1的双特异性嵌合抗原受体及其应用
CN114113634A (zh) * 2022-01-24 2022-03-01 中国农业大学 一种检测非洲猪瘟病毒抗体的ELISA检测试剂盒以及protein L的应用
WO2024258943A1 (en) * 2023-06-13 2024-12-19 Merck Sharp & Dohme Llc Methods of using cyclic peptides for trapping interleukin-1 beta
CN117964755B (zh) * 2023-12-26 2025-01-21 华润生物医药有限公司 抗tslp抗体及其用途

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0020685D0 (en) * 2000-08-22 2000-10-11 Novartis Ag Organic compounds
US20030026806A1 (en) 2000-10-27 2003-02-06 Amgen Inc. Antibodies and other selective IL-1 binding agents that allow binding to IL-1 receptor but not activation thereof
EP2332989B1 (en) 2002-05-22 2015-04-01 ESBATech, an Alcon Biomedical Research Unit LLC Immunoglobulin frameworks which demonstrate enhanced stability in the intracellular environment and methods of identifying same
ES2567198T3 (es) * 2003-01-24 2016-04-20 Applied Molecular Evolution, Inc. Antagonistas de la IL-1 beta humana
WO2006081139A2 (en) 2005-01-26 2006-08-03 Abgenix, Inc. Antibodies against interleukin-1 beta
JP5089582B2 (ja) 2005-06-07 2012-12-05 エスバテック、アン アルコン バイオメディカル リサーチ ユニット、エルエルシー TNFαを阻害する安定な可溶性抗体
EP2163562B1 (en) * 2005-06-21 2013-09-18 XOMA Technology Ltd. IL-1beta binding antibodies and fragments thereof
HRP20130042T1 (hr) * 2008-06-06 2013-03-31 Xoma Technology Ltd. Postupci lijeäśenja reumatoidnog artritisa
GB0811574D0 (en) 2008-06-24 2008-07-30 Trillion Genomics Ltd Characterising planar samples by mass spectrometry
GB2461273A (en) 2008-06-24 2009-12-30 Seppo Haekkinen Load monitoring system
US9556265B2 (en) 2008-06-25 2017-01-31 Esbatech, An Alcon Biomedical Research Unit Llc Solubility optimization of immunobinders
CN104004094B (zh) 2008-06-25 2017-09-22 艾斯巴技术-诺华有限责任公司 使用通用抗体构架进行的兔抗体的人源化
JP2012502059A (ja) 2008-09-05 2012-01-26 ゾーマ テクノロジー リミテッド IL−1β関連疾患を処置または予防するための方法
RU2013115927A (ru) * 2010-09-10 2014-10-20 Апексиджен, Инк. АНТИТЕЛА ПРОТИВ ИЛ-1β И СПОСОБЫ ПРИМЕНЕНИЯ
WO2014068132A1 (en) * 2012-11-05 2014-05-08 Delenex Therapeutics Ag Binding members to il-1 beta

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