CA2888583C - Binding members to il-1 beta - Google Patents
Binding members to il-1 beta Download PDFInfo
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- CA2888583C CA2888583C CA2888583A CA2888583A CA2888583C CA 2888583 C CA2888583 C CA 2888583C CA 2888583 A CA2888583 A CA 2888583A CA 2888583 A CA2888583 A CA 2888583A CA 2888583 C CA2888583 C CA 2888583C
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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- C07K2317/622—Single chain antibody (scFv)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- G01N2333/52—Assays involving cytokines
- G01N2333/54—Interleukins [IL]
- G01N2333/545—IL-1
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- Chemical & Material Sciences (AREA)
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| US61/722,532 | 2012-11-05 | ||
| PCT/EP2013/073009 WO2014068132A1 (en) | 2012-11-05 | 2013-11-05 | Binding members to il-1 beta |
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| US9078427B1 (en) | 2014-08-29 | 2015-07-14 | Pioneer Hi Bred International Inc | Method of storing plant embryos |
| WO2016032629A1 (en) | 2014-08-29 | 2016-03-03 | Pioneer Hi-Bred International, Inc. | Methods and devices involving oil matrices |
| JP6202652B1 (ja) * | 2016-12-19 | 2017-09-27 | 株式会社ヘルスケアシステムズ | 抗エクオール抗体組成物及びその利用 |
| CN107362351B (zh) * | 2017-09-04 | 2020-11-10 | 上海市儿童医院 | Il-36r的拮抗剂在制备镇痛药物中的应用 |
| CN110818793A (zh) * | 2018-08-14 | 2020-02-21 | 中山康方生物医药有限公司 | 抗IL-1β的抗体、其药物组合物及其用途 |
| US20220161243A1 (en) | 2019-02-28 | 2022-05-26 | Exxonmobil Chemical Patents Inc. | Catalyst Compositions and Precursors, Processes for Making the Same and Syngas Conversion Processes |
| TWI793503B (zh) * | 2020-01-20 | 2023-02-21 | 美商美國禮來大藥廠 | 抗IL-1β抗體 |
| MX2023005699A (es) | 2020-11-18 | 2023-05-29 | Novartis Ag | Anticuerpos biespecificos para el uso en el tratamiento de inflamasomopatia nlrc4-gof. |
| EP4267622A1 (en) * | 2020-12-23 | 2023-11-01 | Numab Therapeutics AG | Antibody variable domains and antibodies having decreased immunogenicity |
| WO2022136693A1 (en) * | 2020-12-23 | 2022-06-30 | Numab Therapeutics AG | Antibody variable domains and antibodies having decreased immunogenicity |
| CN113908589B (zh) * | 2021-10-08 | 2022-09-27 | 天津工业大学 | 一种表面印迹抗体的疏水电荷诱导模式膜层析介质及其制备方法 |
| CN116410331B (zh) * | 2021-12-31 | 2024-01-30 | 合源生物科技(天津)有限公司 | 靶向cs1的嵌合抗原受体、靶向bcma/cs1的双特异性嵌合抗原受体及其应用 |
| CN116068192A (zh) * | 2022-01-24 | 2023-05-05 | 中国农业大学 | 一种检测非洲猪瘟病毒抗体的ELISA检测试剂盒以及protein L的应用 |
| AU2024304141A1 (en) * | 2023-06-13 | 2026-01-08 | Merck Sharp & Dohme Llc | Methods of using cyclic peptides for trapping interleukin-1 beta |
| CN119735676B (zh) * | 2023-12-26 | 2025-12-16 | 华润生物医药有限公司 | 抗tslp抗体及其用途 |
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| US20030026806A1 (en) * | 2000-10-27 | 2003-02-06 | Amgen Inc. | Antibodies and other selective IL-1 binding agents that allow binding to IL-1 receptor but not activation thereof |
| CN103739706B (zh) | 2002-05-22 | 2015-11-18 | 艾斯巴技术-诺华有限责任公司 | 在胞内环境中表现出增强的稳定性的免疫球蛋白构架及其鉴定方法 |
| ES2567198T3 (es) * | 2003-01-24 | 2016-04-20 | Applied Molecular Evolution, Inc. | Antagonistas de la IL-1 beta humana |
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| BRPI0611765B1 (pt) | 2005-06-07 | 2022-09-27 | Esbatech Ag | Anticorpo ou fragmento de anticorpo estável e solúvel que se liga especificamente ao tnf-alfa seus usos e composição diagnóstica ou terapêutica |
| KR101366450B1 (ko) * | 2005-06-21 | 2014-03-14 | 조마 테크놀로지 리미티드 | ＩＬ-１β 결합성 항체 및 그의 단편 |
| JP5607613B2 (ja) * | 2008-06-06 | 2014-10-15 | ゾーマ （ユーエス） リミテッド ライアビリティ カンパニー | 関節リウマチの治療のための方法 |
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| GB0811574D0 (en) | 2008-06-24 | 2008-07-30 | Trillion Genomics Ltd | Characterising planar samples by mass spectrometry |
| KR101882352B1 (ko) | 2008-06-25 | 2018-07-26 | 에스바테크 - 어 노바티스 컴파니 엘엘씨 | 보편적 항체 프레임워크를 사용한 래빗 항체의 인간화 |
| CN102076715B (zh) | 2008-06-25 | 2018-06-19 | 艾斯巴技术-诺华有限责任公司 | 免疫结合剂的溶解性优化 |
| AU2009289547A1 (en) * | 2008-09-05 | 2010-03-11 | Xoma (Us) Llc | Methods for treating or preventing IL-1beta related diseases |
| NZ607510A (en) * | 2010-09-10 | 2014-10-31 | Apexigen Inc | Anti-il-1 beta antibodies and methods of use |
| MX374817B (es) * | 2012-11-05 | 2025-03-06 | Delenex Therapeutics Ag | Miembros de union para il-1 beta. |
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| JP6333271B2 (ja) | 2018-06-06 |
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| US10077302B2 (en) | 2018-09-18 |
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| EP2914287B1 (en) | 2020-03-18 |
| CN104870015B (zh) | 2019-07-30 |
| US11267884B2 (en) | 2022-03-08 |
| US20180362642A1 (en) | 2018-12-20 |
| KR102345999B1 (ko) | 2021-12-30 |
| RU2015120450A (ru) | 2016-12-27 |
| JP2018113988A (ja) | 2018-07-26 |
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| BR112015009892A2 (pt) | 2017-08-22 |
| JP2016503293A (ja) | 2016-02-04 |
| US9404930B2 (en) | 2016-08-02 |
| KR20150079753A (ko) | 2015-07-08 |
| MX374817B (es) | 2025-03-06 |
| CN104870015A (zh) | 2015-08-26 |
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