JP2015500864A - 黄色ブドウ球菌(Staphylococcusaureus)に対して免疫するための安定な組成物 - Google Patents
黄色ブドウ球菌(Staphylococcusaureus)に対して免疫するための安定な組成物 Download PDFInfo
- Publication number
- JP2015500864A JP2015500864A JP2014548063A JP2014548063A JP2015500864A JP 2015500864 A JP2015500864 A JP 2015500864A JP 2014548063 A JP2014548063 A JP 2014548063A JP 2014548063 A JP2014548063 A JP 2014548063A JP 2015500864 A JP2015500864 A JP 2015500864A
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- JP
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- Prior art keywords
- seq
- antigen
- composition
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- esxab
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/085—Staphylococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161580191P | 2011-12-23 | 2011-12-23 | |
| US61/580,191 | 2011-12-23 | ||
| PCT/EP2012/076609 WO2013092985A1 (en) | 2011-12-23 | 2012-12-21 | Stable compositions for immunising against staphylococcus aureus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015500864A true JP2015500864A (ja) | 2015-01-08 |
| JP2015500864A5 JP2015500864A5 (enExample) | 2015-12-10 |
Family
ID=47520086
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014548063A Pending JP2015500864A (ja) | 2011-12-23 | 2012-12-21 | 黄色ブドウ球菌(Staphylococcusaureus)に対して免疫するための安定な組成物 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20150044251A1 (enExample) |
| EP (1) | EP2793939A1 (enExample) |
| JP (1) | JP2015500864A (enExample) |
| CN (1) | CN104023744A (enExample) |
| WO (1) | WO2013092985A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012214677B2 (en) | 2011-02-08 | 2016-11-10 | Abvacc, Inc. | Immunogenic composition comprising alpha-hemolysin oligopeptides |
| EP2844275B1 (en) * | 2012-04-26 | 2020-05-13 | University of Chicago | Staphylococcal coagulase antigens and methods of their use |
| CN104619336A (zh) | 2012-08-31 | 2015-05-13 | 诺华股份有限公司 | 用于针对金黄色葡萄球菌的免疫的稳定化的蛋白质 |
| WO2015082536A1 (en) * | 2013-12-03 | 2015-06-11 | Evaxion Biotech Aps | Proteins and nucleic acids useful in vaccines targeting staphylococcus aureus |
| EP3122378B1 (en) | 2014-03-26 | 2019-12-11 | GlaxoSmithKline Biologicals S.A. | Mutant staphylococcal antigens |
| CN104147599B (zh) * | 2014-06-24 | 2017-03-01 | 华中科技大学 | 一种疫苗佐剂、其制备方法及应用 |
| WO2016095832A1 (en) * | 2014-12-18 | 2016-06-23 | The University Of Hong Kong | Immunotherapeutic targets against staphylococcus aureus |
| EP3419654B1 (en) | 2016-02-22 | 2022-04-27 | Evaxion Biotech A/S | Proteins and nucleic acids useful in vaccines targeting staphylococcus aureus |
| CN113893340B (zh) * | 2021-09-30 | 2024-10-22 | 中牧实业股份有限公司 | 双相油佐剂口蹄疫疫苗的稳定剂及其应用 |
| CA3251528A1 (en) * | 2022-05-04 | 2023-11-09 | Evaxion Biotech As | VARIANTS OF STAPHYLOCOCCAL PROTEIN AND TRUNCATED PARTS |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003525909A (ja) * | 2000-03-07 | 2003-09-02 | メルク エンド カムパニー インコーポレーテッド | アデノウイルス製剤 |
| JP2005538939A (ja) * | 2002-04-11 | 2005-12-22 | メディミューン・ヴァクシンズ・インコーポレーテッド | 凍結乾燥フォームによる生物活性材料の保存 |
| JP2006519028A (ja) * | 2003-02-25 | 2006-08-24 | メッドイミューン バクシーンズ、インコーポレイティド | インフルエンザワクチン組成物を生成する方法 |
| JP2008179636A (ja) * | 1994-06-02 | 2008-08-07 | Quadrant Drug Delivery Ltd | 各種物質の再水和または融解時の凝集を防止する方法及び該方法により得られる組成物 |
| JP2008266341A (ja) * | 2004-05-21 | 2008-11-06 | Novartis Vaccines & Diagnostic Inc | 呼吸器系病原体ワクチンのためのアルファウイルスベクター |
| JP2009508866A (ja) * | 2005-09-16 | 2009-03-05 | メリアル リミテッド | 凍結乾燥ワクチン用安定剤 |
| WO2010061193A2 (en) * | 2008-11-28 | 2010-06-03 | Circassia Limited | Compositions with reduced dimer formation |
| WO2010119343A2 (en) * | 2009-04-14 | 2010-10-21 | Novartis Ag | Compositions for immunising against staphylococcus aureus |
| JP2011132234A (ja) * | 2003-10-23 | 2011-07-07 | Novartis Vaccines & Diagnostics Inc | 安定化組成物 |
| JP2011137047A (ja) * | 1999-12-02 | 2011-07-14 | Novartis Vaccines & Diagnostics Inc | 凍結乾燥の際に生物学的分子を安定化するための組成物および方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK331087A (da) * | 1986-06-30 | 1987-12-31 | Smith Kline Rit | Stabilisator for levende vaccine |
| HU212924B (en) | 1989-05-25 | 1996-12-30 | Chiron Corp | Adjuvant formulation comprising a submicron oil droplet emulsion |
| WO1995011700A1 (en) | 1993-10-29 | 1995-05-04 | Pharmos Corp. | Submicron emulsions as vaccine adjuvants |
| US6080725A (en) | 1997-05-20 | 2000-06-27 | Galenica Pharmaceuticals, Inc. | Immunostimulating and vaccine compositions employing saponin analog adjuvants and uses thereof |
| JP2002513773A (ja) | 1998-05-07 | 2002-05-14 | コリクサ コーポレイション | アジュバント組成物及びその使用法 |
| CZ301212B6 (cs) | 1998-10-16 | 2009-12-09 | Smithkline Beecham Biologicals S. A. | Vakcinacní prostredek |
| MXPA01007895A (es) | 1999-02-03 | 2003-07-21 | Biosante Pharmaceuticals Inc | Particulas terapeuticas de fosfato de calcio, metodos de manufactura y usos. |
| AU5731200A (en) * | 1999-06-11 | 2001-01-02 | Endorex Corporation | Adjuvant-containing polymerized liposomes for oral, mucosal or intranasal vaccination |
| UA89631C2 (en) | 2004-04-05 | 2010-02-25 | Пфайзер Продактс Инк. | Vaccine composition |
| MX2007002372A (es) * | 2004-08-27 | 2007-05-08 | Panacea Biotec Ltd | Vacuna para la poliomielitis inactivada derivada de la cepa sabin del virus de la polio. |
| US20060228369A1 (en) | 2005-04-11 | 2006-10-12 | Program For Appropriate Technology In Health | Stabilization and preservation of temperature-sensitive vaccines |
| US7691368B2 (en) | 2005-04-15 | 2010-04-06 | Merial Limited | Vaccine formulations |
| EP1888118B1 (en) * | 2005-05-25 | 2016-08-17 | Novo Nordisk A/S | Polypeptide formulations stabilized with ethylenediamine |
| US8703095B2 (en) | 2005-07-07 | 2014-04-22 | Sanofi Pasteur S.A. | Immuno-adjuvant emulsion |
| BRPI0520505B1 (pt) * | 2005-09-01 | 2015-03-31 | José Luis Nuño Ayalá | Fórmula estabilizadora de vacinas com antígenos vivos para uso em sistemas de vacinação em massa |
| FR2896162B1 (fr) | 2006-01-13 | 2008-02-15 | Sanofi Pasteur Sa | Emulsion huile dans eau thermoreversible |
| CA2637598A1 (en) | 2006-01-18 | 2007-02-14 | University Of Chicago | Compositions and methods related to staphylococcal bacterium proteins |
| AU2007259415B2 (en) | 2006-06-12 | 2013-09-26 | Glaxosmithkline Biologicals Sa | Use of alpha-toxin for treating and preventing Staphylococcus infections |
| CN100460013C (zh) * | 2006-09-05 | 2009-02-11 | 重庆康卫生物科技有限公司 | 口服重组幽门螺杆菌疫苗及其制备方法 |
| CN101522218B (zh) | 2006-10-12 | 2012-09-26 | 葛兰素史密丝克莱恩生物有限公司 | 包含水包油乳液佐剂的疫苗 |
| CA2697538C (en) | 2007-08-31 | 2019-02-12 | University Of Chicago | Methods and compositions related to immunizing against staphylococcal lung diseases and conditions |
| ES2443952T3 (es) | 2009-09-02 | 2014-02-21 | Novartis Ag | Composiciones inmunógenas que incluyen moduladores de la actividad de TLR |
| CN102258537B (zh) * | 2011-07-15 | 2012-07-04 | 骆延波 | 鸡传染性法氏囊病特异性转移因子的制备方法 |
-
2012
- 2012-12-21 WO PCT/EP2012/076609 patent/WO2013092985A1/en not_active Ceased
- 2012-12-21 EP EP12812257.9A patent/EP2793939A1/en not_active Withdrawn
- 2012-12-21 US US14/366,362 patent/US20150044251A1/en not_active Abandoned
- 2012-12-21 JP JP2014548063A patent/JP2015500864A/ja active Pending
- 2012-12-21 CN CN201280063615.8A patent/CN104023744A/zh active Pending
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008179636A (ja) * | 1994-06-02 | 2008-08-07 | Quadrant Drug Delivery Ltd | 各種物質の再水和または融解時の凝集を防止する方法及び該方法により得られる組成物 |
| JP2011137047A (ja) * | 1999-12-02 | 2011-07-14 | Novartis Vaccines & Diagnostics Inc | 凍結乾燥の際に生物学的分子を安定化するための組成物および方法 |
| JP2003525909A (ja) * | 2000-03-07 | 2003-09-02 | メルク エンド カムパニー インコーポレーテッド | アデノウイルス製剤 |
| JP2005538939A (ja) * | 2002-04-11 | 2005-12-22 | メディミューン・ヴァクシンズ・インコーポレーテッド | 凍結乾燥フォームによる生物活性材料の保存 |
| JP2006519028A (ja) * | 2003-02-25 | 2006-08-24 | メッドイミューン バクシーンズ、インコーポレイティド | インフルエンザワクチン組成物を生成する方法 |
| JP2011132234A (ja) * | 2003-10-23 | 2011-07-07 | Novartis Vaccines & Diagnostics Inc | 安定化組成物 |
| JP2008266341A (ja) * | 2004-05-21 | 2008-11-06 | Novartis Vaccines & Diagnostic Inc | 呼吸器系病原体ワクチンのためのアルファウイルスベクター |
| JP2009508866A (ja) * | 2005-09-16 | 2009-03-05 | メリアル リミテッド | 凍結乾燥ワクチン用安定剤 |
| WO2010061193A2 (en) * | 2008-11-28 | 2010-06-03 | Circassia Limited | Compositions with reduced dimer formation |
| WO2010119343A2 (en) * | 2009-04-14 | 2010-10-21 | Novartis Ag | Compositions for immunising against staphylococcus aureus |
Also Published As
| Publication number | Publication date |
|---|---|
| US20150044251A1 (en) | 2015-02-12 |
| WO2013092985A1 (en) | 2013-06-27 |
| EP2793939A1 (en) | 2014-10-29 |
| CN104023744A (zh) | 2014-09-03 |
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Legal Events
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| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20151019 |
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