CN104023744A - 用于针对金黄色葡萄球菌免疫的稳定组合物 - Google Patents

用于针对金黄色葡萄球菌免疫的稳定组合物 Download PDF

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Publication number
CN104023744A
CN104023744A CN201280063615.8A CN201280063615A CN104023744A CN 104023744 A CN104023744 A CN 104023744A CN 201280063615 A CN201280063615 A CN 201280063615A CN 104023744 A CN104023744 A CN 104023744A
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CN
China
Prior art keywords
antigen
seq
sta006
polypeptide
esxab
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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CN201280063615.8A
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English (en)
Chinese (zh)
Inventor
M·肯托尼
L·塔里
A·考斯洛维
M·索特朱
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Novartis AG
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Novartis AG
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Publication of CN104023744A publication Critical patent/CN104023744A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/085—Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
CN201280063615.8A 2011-12-23 2012-12-21 用于针对金黄色葡萄球菌免疫的稳定组合物 Pending CN104023744A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161580191P 2011-12-23 2011-12-23
US61/580,191 2011-12-23
PCT/EP2012/076609 WO2013092985A1 (en) 2011-12-23 2012-12-21 Stable compositions for immunising against staphylococcus aureus

Publications (1)

Publication Number Publication Date
CN104023744A true CN104023744A (zh) 2014-09-03

Family

ID=47520086

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280063615.8A Pending CN104023744A (zh) 2011-12-23 2012-12-21 用于针对金黄色葡萄球菌免疫的稳定组合物

Country Status (5)

Country Link
US (1) US20150044251A1 (enExample)
EP (1) EP2793939A1 (enExample)
JP (1) JP2015500864A (enExample)
CN (1) CN104023744A (enExample)
WO (1) WO2013092985A1 (enExample)

Cited By (1)

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Publication number Priority date Publication date Assignee Title
CN113893340A (zh) * 2021-09-30 2022-01-07 中牧实业股份有限公司 双相油佐剂口蹄疫疫苗的稳定剂及其应用

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AU2012214677B2 (en) 2011-02-08 2016-11-10 Abvacc, Inc. Immunogenic composition comprising alpha-hemolysin oligopeptides
EP2844275B1 (en) * 2012-04-26 2020-05-13 University of Chicago Staphylococcal coagulase antigens and methods of their use
CN104619336A (zh) 2012-08-31 2015-05-13 诺华股份有限公司 用于针对金黄色葡萄球菌的免疫的稳定化的蛋白质
WO2015082536A1 (en) * 2013-12-03 2015-06-11 Evaxion Biotech Aps Proteins and nucleic acids useful in vaccines targeting staphylococcus aureus
EP3122378B1 (en) 2014-03-26 2019-12-11 GlaxoSmithKline Biologicals S.A. Mutant staphylococcal antigens
CN104147599B (zh) * 2014-06-24 2017-03-01 华中科技大学 一种疫苗佐剂、其制备方法及应用
WO2016095832A1 (en) * 2014-12-18 2016-06-23 The University Of Hong Kong Immunotherapeutic targets against staphylococcus aureus
EP3419654B1 (en) 2016-02-22 2022-04-27 Evaxion Biotech A/S Proteins and nucleic acids useful in vaccines targeting staphylococcus aureus
CA3251528A1 (en) * 2022-05-04 2023-11-09 Evaxion Biotech As VARIANTS OF STAPHYLOCOCCAL PROTEIN AND TRUNCATED PARTS

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EP0252059A2 (fr) * 1986-06-30 1988-01-07 Smithkline Biologicals S.A. Stabilisants améliorés pour vaccins atténués, procédé pour leur préparation et vaccins les contenant
WO2007007344A1 (en) * 2004-08-27 2007-01-18 Panacea Biotec Ltd. Inactivated poliomyelitis vaccine derived from sabin strain of polio virus
WO2007027076A1 (es) * 2005-09-01 2007-03-08 Nuno Ayala Jose Luis Formula estabilizadora de vacunas con antígenos vivos para su uso en sistemas de vacunación masiva
CN1927394A (zh) * 2006-09-05 2007-03-14 重庆康卫生物科技有限公司 口服重组幽门螺杆菌疫苗及其制备方法
WO2010119343A2 (en) * 2009-04-14 2010-10-21 Novartis Ag Compositions for immunising against staphylococcus aureus
CN102258537A (zh) * 2011-07-15 2011-11-30 骆延波 鸡传染性法氏囊病特异性转移因子的制备方法

Non-Patent Citations (1)

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CAVALLIN A ET AL: "The spectral and thermodynamic properties of staphylococcal enterotoxin A,E,and variants suggest that structural modification are improtant to control their function", 《THE JOURNAL OF BIOLOGICAL CHEMISTRY》, vol. 275, no. 3, 21 January 2000 (2000-01-21), pages 1665 - 1672 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113893340A (zh) * 2021-09-30 2022-01-07 中牧实业股份有限公司 双相油佐剂口蹄疫疫苗的稳定剂及其应用

Also Published As

Publication number Publication date
JP2015500864A (ja) 2015-01-08
US20150044251A1 (en) 2015-02-12
WO2013092985A1 (en) 2013-06-27
EP2793939A1 (en) 2014-10-29

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Application publication date: 20140903