JP2015500467A - 粒径及び濃度測定のための検出スキーム - Google Patents
粒径及び濃度測定のための検出スキーム Download PDFInfo
- Publication number
- JP2015500467A JP2015500467A JP2014544046A JP2014544046A JP2015500467A JP 2015500467 A JP2015500467 A JP 2015500467A JP 2014544046 A JP2014544046 A JP 2014544046A JP 2014544046 A JP2014544046 A JP 2014544046A JP 2015500467 A JP2015500467 A JP 2015500467A
- Authority
- JP
- Japan
- Prior art keywords
- particles
- dark field
- particle
- signal
- detector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002245 particle Substances 0.000 title claims abstract description 120
- 238000001514 detection method Methods 0.000 title description 16
- 238000005259 measurement Methods 0.000 title description 16
- 238000012544 monitoring process Methods 0.000 claims description 12
- 230000005855 radiation Effects 0.000 claims description 7
- 230000003993 interaction Effects 0.000 abstract description 39
- 238000000034 method Methods 0.000 abstract description 23
- 241000195493 Cryptophyta Species 0.000 description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- 230000003287 optical effect Effects 0.000 description 8
- 230000008901 benefit Effects 0.000 description 6
- 238000007562 laser obscuration time method Methods 0.000 description 5
- 239000004816 latex Substances 0.000 description 5
- 229920000126 latex Polymers 0.000 description 5
- 238000004088 simulation Methods 0.000 description 5
- 238000004458 analytical method Methods 0.000 description 3
- 238000013459 approach Methods 0.000 description 3
- 238000009792 diffusion process Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 238000012795 verification Methods 0.000 description 3
- 238000013473 artificial intelligence Methods 0.000 description 2
- 238000012512 characterization method Methods 0.000 description 2
- 230000001419 dependent effect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 238000005286 illumination Methods 0.000 description 2
- 238000003921 particle size analysis Methods 0.000 description 2
- 241000195649 Chlorella <Chlorellales> Species 0.000 description 1
- 241000196152 Pediastrum Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 230000006399 behavior Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 238000001739 density measurement Methods 0.000 description 1
- 238000002050 diffraction method Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000007850 fluorescent dye Substances 0.000 description 1
- 238000010191 image analysis Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000013507 mapping Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000010363 phase shift Effects 0.000 description 1
- 230000010287 polarization Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000004513 sizing Methods 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- 238000010200 validation analysis Methods 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/02—Investigating particle size or size distribution
- G01N15/0205—Investigating particle size or size distribution by optical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/06—Investigating concentration of particle suspensions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
- G01N15/1436—Optical arrangements the optical arrangement forming an integrated apparatus with the sample container, e.g. a flow cell
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/06—Investigating concentration of particle suspensions
- G01N15/075—Investigating concentration of particle suspensions by optical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
- G01N2015/1447—Spatial selection
- G01N2015/145—Spatial selection by pattern of light, e.g. fringe pattern
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
- G01N2015/1454—Optical arrangements using phase shift or interference, e.g. for improving contrast
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
Description
a)個別の信号、
b)2つのディテクタ信号の差分信号、及び
c)2つのディテクタ信号の和のうちの少なくとも1つとして記録される。
b)2つのディテクタ信号の差分信号
c)2つのディテクタ信号の和
他の実施形態においては暗視野ビームの暗線(dark line)に直交する方向において、ビームスプリッタを介して、2つの前方ディテクタ(forward detector)の第2の組を使用する。これらの2つのディテクタは、ビームサイズに対して大きく、総合的なビーム強度を統合する。図12は、この実施形態における照射暗視野ビームパターンに対するディテクタの第2の組の位置を示している。これらの2つのディテクタからの信号の対称性を確認することによって、粒子が直径に沿って焦点ゾーンを横切った(信号が等しい)か、弦に沿って焦点ゾーンを横切った(信号が異なる)かを推定でき、及び粒径に関する重要な情報、例えば、信号におけるインタラクションの幅又は変調の深さを推定できる。これらの2つの信号のタイミングは、粒子フロー方向の整列、並びに層流の程度及び光軸への垂直の度合い等の情報を提供する。
・後方散乱ディテクタ(30)の明白な用途は、焦点において粒子とのインタラクションが実際にあったかを確認するための共焦点検出スキームである。
・λ=400nm
図10Aでは、暗視野ビームの信号は、他の2つのビーム構造の信号に比べて、約2倍高くなっている。曲線の符号の違いは、実質的なものではなく、粒子方向に対する減算におけるディテクタの順序に依存する。
Claims (5)
- ガウスビームを生成するレーザと、
前記ガウスレーザビームを構造化された暗視野ビームに変換する手段と、
前記暗視野ビームを、照射されている前記暗視野ビームを通って移動する粒子にフォーカスするフォーカスレンズと、
一方が前記暗視野ビームの各強度ローブ上に配置される2つのディテクタと、を備える粒子監視システム。 - 前記粒子は、前記暗視野ビームの方向に対して90度の角度の方向に、照射されている前記暗視野ビームを通って移動する請求項1記載の粒子監視システム。
- 前記2つのディテクタからの信号は、
a)個別の信号、
b)2つのディテクタ信号の差分信号、及び
c)2つのディテクタ信号の和
のうちの少なくとも1つとして記録される請求項1記載の粒子監視システム。 - 前記暗視野ビームの暗線に直交する方向に向けられたビームスプリッタ及びディテクタの第2の組を備える請求項1記載の粒子監視システム。
- 粒子からの後方散乱放射の同時測定を行うように構成されたビームスプリッタ及び第3のディテクタを備える請求項1記載の粒子監視システム。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161565529P | 2011-12-01 | 2011-12-01 | |
US61/565,529 | 2011-12-01 | ||
PCT/IL2012/050488 WO2013080209A1 (en) | 2011-12-01 | 2012-11-29 | Detection scheme for particle size and concentration measurement |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2015500467A true JP2015500467A (ja) | 2015-01-05 |
JP6309896B2 JP6309896B2 (ja) | 2018-04-11 |
Family
ID=48534768
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014544046A Active JP6309896B2 (ja) | 2011-12-01 | 2012-11-29 | 粒径及び濃度測定のための検出スキーム |
Country Status (8)
Country | Link |
---|---|
US (4) | US20150260628A1 (ja) |
EP (2) | EP2786117B1 (ja) |
JP (1) | JP6309896B2 (ja) |
KR (1) | KR102104987B1 (ja) |
CN (1) | CN103959039A (ja) |
CA (1) | CA2856664A1 (ja) |
SG (1) | SG11201402528TA (ja) |
WO (1) | WO2013080209A1 (ja) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2017516112A (ja) * | 2014-03-12 | 2017-06-15 | ネックスジェン・パートナーズ・アイピー・リミテッド・ライアビリティ・カンパニーNxGen Partners IP, LLC | 軌道角運動量を用いてサンプル物質内の濃度測定を行うシステムおよび方法 |
JP2019536997A (ja) * | 2016-10-11 | 2019-12-19 | マルバーン パナリティカル リミテッド | 粒子特性測定装置 |
WO2020067149A1 (ja) * | 2018-09-28 | 2020-04-02 | 国立大学法人東京大学 | 微粒子検出装置 |
JP2021500533A (ja) * | 2017-10-26 | 2021-01-07 | パーティクル・メージャーリング・システムズ・インコーポレーテッド | 粒子計測システム及び方法 |
JP7504912B2 (ja) | 2019-04-25 | 2024-06-24 | パーティクル・メージャーリング・システムズ・インコーポレーテッド | 軸上粒子検出及び/又は差分検出のための粒子検出システム及び方法 |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2856664A1 (en) | 2011-12-01 | 2013-06-06 | P.M.L. - Particles Monitoring Technologies Ltd. | Detection scheme for particle size and concentration measurement |
ITRM20130128U1 (it) | 2013-07-23 | 2015-01-24 | Particle Measuring Systems S R L | Dispositivo per il campionamento microbico dell'aria |
JP2016103590A (ja) * | 2014-11-28 | 2016-06-02 | 東京エレクトロン株式会社 | 基板処理方法及び基板処理装置 |
PL3308136T3 (pl) * | 2015-06-12 | 2022-04-11 | Koninklijke Philips N.V. | Czujnik optyczny cząstek i sposób wykrywania |
EP3458837B1 (en) * | 2016-05-19 | 2022-11-16 | The Regents of The University of Colorado, A Body Corporate | Spatially-resolved complex reflectometry/refractometry |
CN108226015A (zh) * | 2018-01-04 | 2018-06-29 | 江苏苏净集团有限公司 | 一种新型液体颗粒计数方法及系统 |
GB201803523D0 (en) * | 2018-03-05 | 2018-04-18 | Malvern Panalytical Ltd | Improved particle sizing by optical diffraction |
WO2020047457A1 (en) | 2018-08-31 | 2020-03-05 | Particle Measuring Systems, Inc. | Fluid refractive index optimizing particle counter |
US10928293B2 (en) | 2018-09-04 | 2021-02-23 | Particle Measuring Systems, Inc. | Detecting nanoparticles on production equipment and surfaces |
US11181455B2 (en) | 2018-11-12 | 2021-11-23 | Particle Measuring Systems, Inc. | Calibration verification for optical particle analyzers |
US11385161B2 (en) | 2018-11-12 | 2022-07-12 | Particle Measuring Systems, Inc. | Calibration verification for optical particle analyzers |
JP7436473B2 (ja) | 2018-11-16 | 2024-02-21 | パーティクル・メージャーリング・システムズ・インコーポレーテッド | ロボット制御製造バリアシステムのための粒子サンプリングシステム及び方法 |
US10908059B2 (en) | 2018-11-16 | 2021-02-02 | Particle Measuring Systems, Inc. | Slurry monitor coupling bulk size distribution and single particle detection |
RU2722066C2 (ru) * | 2018-11-19 | 2020-05-26 | Самсунг Электроникс Ко., Лтд. | Многоканальный датчик пыли |
KR102142248B1 (ko) | 2019-04-12 | 2020-08-07 | (주)에이치앤지텍 | 압축 공기의 입자 측정 장치 |
WO2020219841A1 (en) | 2019-04-25 | 2020-10-29 | Particle Measuring Systems, Inc. | Particle detection systems and methods for on-axis particle detection and/or differential detection |
CN114270165A (zh) | 2019-08-26 | 2022-04-01 | 粒子监测系统有限公司 | 触发式采样系统和方法 |
EP4041462A4 (en) | 2019-10-07 | 2022-12-14 | Particle Measuring Systems, Inc. | ANTIMICROBIAL PARTICLE DETECTORS |
US10997845B2 (en) | 2019-10-07 | 2021-05-04 | Particle Measuring Systems, Inc. | Particle detectors with remote alarm monitoring and control |
US11733149B2 (en) * | 2019-10-10 | 2023-08-22 | Kansas State University Research Foundation | Monitor for environmental particulate matter size, concentration, and complex index of refraction |
IT201900020248A1 (it) | 2019-11-04 | 2021-05-04 | Particle Measuring Systems S R L | Dispositivo di monitoraggio mobile per aree a contaminazione controllata |
WO2021102256A1 (en) * | 2019-11-22 | 2021-05-27 | Particle Measuring Systems, Inc. | Advanced systems and methods for interferometric particle detection and detection of particles having small size dimensions |
EP4094061A1 (en) | 2020-01-21 | 2022-11-30 | Particle Measuring Systems, Inc. | Robotic control for aseptic processing |
WO2022114733A1 (ko) * | 2020-11-27 | 2022-06-02 | 삼성전자 주식회사 | 입자 사이즈 분포를 결정하는 방법 및 전자 장치 |
CN112730174A (zh) * | 2020-12-17 | 2021-04-30 | 华南理工大学 | 一种实时监测结晶过程中类球形颗粒浓度的方法 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5737251A (en) * | 1980-08-19 | 1982-03-01 | Keisho Amano | Optical system of measuring device of grain density in suspension liquid |
JPH04188041A (ja) * | 1990-11-21 | 1992-07-06 | Canon Inc | 検体測定装置 |
JPH0854388A (ja) * | 1983-10-31 | 1996-02-27 | Technicon Instr Corp | 粒子の容積および屈折率の測定用装置 |
JP2005536740A (ja) * | 2002-08-23 | 2005-12-02 | コールター インターナショナル コーポレイション | 血液細胞及びこれに類するものを分化するために光散乱を検出するための光ファイバ装置 |
US7746469B2 (en) * | 2003-07-09 | 2010-06-29 | P.M.L-Particles Monitoring Technologies, Ltd. | Method for particle size and concentration measurement |
JP2011133460A (ja) * | 2009-11-30 | 2011-07-07 | Sysmex Corp | 粒子分析装置 |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2526708B1 (fr) | 1982-05-17 | 1985-07-12 | Michelin & Cie | Procede pour solidariser les fils d'une tringle pour pneumatiques |
US4623252A (en) * | 1984-10-09 | 1986-11-18 | Spectrex Corporation | Particulate counter |
US4906094A (en) | 1987-04-23 | 1990-03-06 | Sumitomo Chemical Co. Ltd. | Fine particle measuring method and system and a flow cell for use in the system |
US4806774A (en) | 1987-06-08 | 1989-02-21 | Insystems, Inc. | Inspection system for array of microcircuit dies having redundant circuit patterns |
US4917494A (en) * | 1987-07-28 | 1990-04-17 | Amherst Process Instruments, Inc. | Beam forming apparatus for aerodynamic particle sizing system |
US4963003A (en) * | 1988-02-22 | 1990-10-16 | Fuji Photo Film Co., Ltd. | Laser optical system |
US4854705A (en) * | 1988-04-05 | 1989-08-08 | Aerometrics, Inc. | Method and apparatus to determine the size and velocity of particles using light scatter detection from confocal beams |
US5063301A (en) | 1989-12-21 | 1991-11-05 | The Standard Oil Company | Noninvasive method and apparatus using coherent backscattering for process control |
US5999256A (en) | 1992-02-12 | 1999-12-07 | Cambridge Consultants Limited | Particle measurement system |
JP2722362B2 (ja) | 1992-03-27 | 1998-03-04 | 三井金属鉱業株式会社 | 粒子または欠陥の大きさ情報の測定方法および装置 |
EP0722574B1 (en) | 1993-10-04 | 1998-09-09 | International Business Machines Corporation | Near-field optical microscope |
US5619043A (en) * | 1994-09-21 | 1997-04-08 | Laser Sensor Technology, Inc. | System for acquiring an image of a multi-phase fluid by measuring backscattered light |
US5719667A (en) * | 1996-07-30 | 1998-02-17 | Bayer Corporation | Apparatus for filtering a laser beam in an analytical instrument |
EP1007944A4 (en) | 1997-05-06 | 2000-07-12 | Matthew J Holcomb | SURFACE ANALYSIS WITH USE OF THE GAUSS PROFILE OF THE MEASURING BEAM |
US6608676B1 (en) | 1997-08-01 | 2003-08-19 | Kla-Tencor Corporation | System for detecting anomalies and/or features of a surface |
US6137572A (en) | 1998-02-27 | 2000-10-24 | Pacific Scientific Instruments Company | High sensitivity optical fluid-borne particle detection |
US6707544B1 (en) | 1999-09-07 | 2004-03-16 | Applied Materials, Inc. | Particle detection and embedded vision system to enhance substrate yield and throughput |
AU2002245395A1 (en) | 2001-02-07 | 2002-08-19 | University Of Rochester | A system and method for high resolution optical imaging, data storage, lithography, and inspection |
US7092078B2 (en) * | 2003-03-31 | 2006-08-15 | Nihon Kohden Corporation | Flow cytometer for classifying leukocytes and method for determining detection angle range of the same |
CN1587984A (zh) * | 2004-10-19 | 2005-03-02 | 天津大学 | 激光相位多普勒粉尘粒子监测方法及装置 |
CN101107508B (zh) * | 2005-01-17 | 2011-08-10 | 比奥菲斯股份公司 | 用于测量粒子动态参数的方法和装置 |
WO2007084175A1 (en) | 2005-05-04 | 2007-07-26 | University Of Rochester | Interferometric apparatus and method for sizing nanoparticles |
US20090323061A1 (en) | 2006-02-28 | 2009-12-31 | Lukas Novotny | Multi-color hetereodyne interferometric apparatus and method for sizing nanoparticles |
CN101153868B (zh) | 2006-09-30 | 2012-05-30 | 深圳迈瑞生物医疗电子股份有限公司 | 流式细胞分析仪 |
CN101236150B (zh) * | 2007-02-02 | 2012-09-05 | 深圳迈瑞生物医疗电子股份有限公司 | 用于基于流式细胞术的仪器的光电传感器及其照射单元 |
US7630147B1 (en) * | 2007-02-16 | 2009-12-08 | University Of Central Florida Research Foundation, Inc. | Laser beam shaping for pitchfork profile |
GB0704491D0 (en) | 2007-03-08 | 2007-04-18 | Univ St Andrews | Enhanced spectroscopic techniques using spatial beam shaping |
US7876450B2 (en) | 2007-09-14 | 2011-01-25 | University Of Rochester | Common-path interferometer rendering amplitude and phase of scattered light |
CA2856664A1 (en) | 2011-12-01 | 2013-06-06 | P.M.L. - Particles Monitoring Technologies Ltd. | Detection scheme for particle size and concentration measurement |
CN104641217B (zh) | 2012-05-30 | 2019-02-22 | 艾瑞斯国际有限公司 | 流式细胞仪 |
US9857284B1 (en) | 2013-07-15 | 2018-01-02 | Stratedigm, Inc. | Method and apparatus for detection and measurement of particles with a wide dynamic range of measurement |
US9952136B2 (en) | 2015-01-21 | 2018-04-24 | Stratedigm, Inc. | Systems and methods for detecting a particle |
EP3397946B1 (en) | 2015-12-30 | 2021-12-01 | Bio-Rad Laboratories, Inc. | Optical detection system for particles |
WO2018170257A1 (en) | 2017-03-16 | 2018-09-20 | Symmetry Sensors, Inc. | System and method for particle characterization |
KR20230156814A (ko) | 2017-10-26 | 2023-11-14 | 파티클 머슈어링 시스템즈, 인크. | 입자 측정을 위한 시스템 및 방법 |
-
2012
- 2012-11-29 CA CA2856664A patent/CA2856664A1/en not_active Abandoned
- 2012-11-29 EP EP12854152.1A patent/EP2786117B1/en active Active
- 2012-11-29 US US14/359,233 patent/US20150260628A1/en not_active Abandoned
- 2012-11-29 WO PCT/IL2012/050488 patent/WO2013080209A1/en active Application Filing
- 2012-11-29 EP EP22211154.4A patent/EP4180794A3/en active Pending
- 2012-11-29 CN CN201280059154.7A patent/CN103959039A/zh active Pending
- 2012-11-29 SG SG11201402528TA patent/SG11201402528TA/en unknown
- 2012-11-29 JP JP2014544046A patent/JP6309896B2/ja active Active
- 2012-11-29 KR KR1020147017139A patent/KR102104987B1/ko active IP Right Grant
-
2017
- 2017-02-23 US US15/440,287 patent/US10921229B2/en active Active
-
2019
- 2019-11-11 US US16/680,125 patent/US20200150018A1/en not_active Abandoned
-
2022
- 2022-01-06 US US17/570,228 patent/US20220228963A1/en active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5737251A (en) * | 1980-08-19 | 1982-03-01 | Keisho Amano | Optical system of measuring device of grain density in suspension liquid |
JPH0854388A (ja) * | 1983-10-31 | 1996-02-27 | Technicon Instr Corp | 粒子の容積および屈折率の測定用装置 |
JPH04188041A (ja) * | 1990-11-21 | 1992-07-06 | Canon Inc | 検体測定装置 |
JP2005536740A (ja) * | 2002-08-23 | 2005-12-02 | コールター インターナショナル コーポレイション | 血液細胞及びこれに類するものを分化するために光散乱を検出するための光ファイバ装置 |
US7746469B2 (en) * | 2003-07-09 | 2010-06-29 | P.M.L-Particles Monitoring Technologies, Ltd. | Method for particle size and concentration measurement |
JP2011133460A (ja) * | 2009-11-30 | 2011-07-07 | Sysmex Corp | 粒子分析装置 |
Non-Patent Citations (1)
Title |
---|
JOSEPH SHAMIR: "Singular beams in metrology and nanotechnology", SPIE, vol. 8122, JPN6017033785, 21 September 2011 (2011-09-21), pages 1 - 81220, ISSN: 0003745181 * |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2017516112A (ja) * | 2014-03-12 | 2017-06-15 | ネックスジェン・パートナーズ・アイピー・リミテッド・ライアビリティ・カンパニーNxGen Partners IP, LLC | 軌道角運動量を用いてサンプル物質内の濃度測定を行うシステムおよび方法 |
JP2019536997A (ja) * | 2016-10-11 | 2019-12-19 | マルバーン パナリティカル リミテッド | 粒子特性測定装置 |
JP7114580B2 (ja) | 2016-10-11 | 2022-08-08 | マルバーン パナリティカル リミテッド | 粒子特性測定装置 |
JP2021500533A (ja) * | 2017-10-26 | 2021-01-07 | パーティクル・メージャーリング・システムズ・インコーポレーテッド | 粒子計測システム及び方法 |
JP7326256B2 (ja) | 2017-10-26 | 2023-08-15 | パーティクル・メージャーリング・システムズ・インコーポレーテッド | 粒子計測システム及び方法 |
WO2020067149A1 (ja) * | 2018-09-28 | 2020-04-02 | 国立大学法人東京大学 | 微粒子検出装置 |
JPWO2020067149A1 (ja) * | 2018-09-28 | 2021-08-30 | 国立大学法人 東京大学 | 微粒子検出装置 |
JP7333637B2 (ja) | 2018-09-28 | 2023-08-25 | 国立大学法人 東京大学 | 微粒子検出装置 |
JP7504912B2 (ja) | 2019-04-25 | 2024-06-24 | パーティクル・メージャーリング・システムズ・インコーポレーテッド | 軸上粒子検出及び/又は差分検出のための粒子検出システム及び方法 |
Also Published As
Publication number | Publication date |
---|---|
KR20140106595A (ko) | 2014-09-03 |
US20170176312A1 (en) | 2017-06-22 |
KR102104987B1 (ko) | 2020-04-28 |
EP2786117B1 (en) | 2022-12-21 |
US20150260628A1 (en) | 2015-09-17 |
WO2013080209A1 (en) | 2013-06-06 |
EP2786117A4 (en) | 2015-07-08 |
EP4180794A2 (en) | 2023-05-17 |
EP2786117A1 (en) | 2014-10-08 |
CA2856664A1 (en) | 2013-06-06 |
CN103959039A (zh) | 2014-07-30 |
US10921229B2 (en) | 2021-02-16 |
US20220228963A1 (en) | 2022-07-21 |
US20200150018A1 (en) | 2020-05-14 |
SG11201402528TA (en) | 2014-10-30 |
EP4180794A3 (en) | 2023-08-09 |
JP6309896B2 (ja) | 2018-04-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP6309896B2 (ja) | 粒径及び濃度測定のための検出スキーム | |
KR102315741B1 (ko) | 나노 입자 분석기 | |
JP6559555B2 (ja) | 光計測方法および装置 | |
US7746469B2 (en) | Method for particle size and concentration measurement | |
JP5381741B2 (ja) | 光学的測定装置及び光学的測定方法 | |
US10467764B2 (en) | Method for counting and characterization of particles in a fluid in movement | |
JPWO2016163560A1 (ja) | ディジタルホログラフィック顕微鏡 | |
US7362421B2 (en) | Analysis of signal oscillation patterns | |
JP2016048183A (ja) | 気泡径分布測定方法及び気泡径分布測定装置 | |
Geilhufe et al. | Extracting depth information of 3-dimensional structures from a single-view X-ray Fourier-transform hologram | |
JP3745947B2 (ja) | 流体中の微粒子粒径測定方法および装置 | |
CN108562522B (zh) | 一种粒子尺寸和折射率同时测量方法 | |
JP6808213B2 (ja) | 情報処理システム及び情報処理方法 | |
JP4888673B2 (ja) | 光学的測定装置およびその電極対 | |
Rajan et al. | Influence of tissue optical properties on laser Doppler perfusion imaging, accounting for photon penetration depth and the laser speckle phenomenon | |
JP2746852B2 (ja) | 透過光測定装置 | |
EP3797280B1 (en) | Apparatus and method for the characterization of objects by analysis of scattered radiation | |
Hanna | Asymmetry in Mie scattering by a homogeneous sphere | |
US20240027958A1 (en) | Method and arrangement for holographic nanoparticle tracking analysis (h-nta) in a digital holographic microscope | |
TW202346835A (zh) | 增強的雙遍次及多遍次粒子偵測 | |
JP2022529213A (ja) | 軸上粒子検出及び/又は差分検出のための粒子検出システム及び方法 | |
Tcherniak | Development and Application of Methods to Study Nanoparticle Diffusion Using Intensity Correlation Spectroscopy | |
Cannaday | Improved time-lapsed angular scattering microscopy of single cells | |
Oh et al. | Measurement of the forward light scattering from polystyrene spheres with a barium titanate crystal | |
JPH09196842A (ja) | Fi値の計測方法と計測装置 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RD01 | Notification of change of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7426 Effective date: 20141219 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A821 Effective date: 20141219 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20151006 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20160823 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20161004 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20161227 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20170331 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20170905 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20171116 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20180213 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20180227 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20180315 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 6309896 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313113 |
|
S531 | Written request for registration of change of domicile |
Free format text: JAPANESE INTERMEDIATE CODE: R313531 |
|
R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |