JP2015500032A5 - - Google Patents
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- JP2015500032A5 JP2015500032A5 JP2014546087A JP2014546087A JP2015500032A5 JP 2015500032 A5 JP2015500032 A5 JP 2015500032A5 JP 2014546087 A JP2014546087 A JP 2014546087A JP 2014546087 A JP2014546087 A JP 2014546087A JP 2015500032 A5 JP2015500032 A5 JP 2015500032A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- protein
- microorganism
- seq
- promoter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161569202P | 2011-12-09 | 2011-12-09 | |
| US61/569,202 | 2011-12-09 | ||
| US201161577491P | 2011-12-19 | 2011-12-19 | |
| US61/577,491 | 2011-12-19 | ||
| PCT/US2012/068285 WO2013086219A1 (en) | 2011-12-09 | 2012-12-06 | Ribosomal promotors from b. subtilis for protein production in microorganisms |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015500032A JP2015500032A (ja) | 2015-01-05 |
| JP2015500032A5 true JP2015500032A5 (cg-RX-API-DMAC7.html) | 2016-01-28 |
| JP6378089B2 JP6378089B2 (ja) | 2018-08-22 |
Family
ID=47436212
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014546087A Active JP6378089B2 (ja) | 2011-12-09 | 2012-12-06 | 微生物におけるタンパク質産生のための、B.ズブチリス(B.subtilis)からのリボソームプロモーター |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20140329309A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2788491B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6378089B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN104053780A (cg-RX-API-DMAC7.html) |
| DK (1) | DK2788491T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013086219A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016134213A2 (en) | 2015-02-19 | 2016-08-25 | Danisco Us Inc | Enhanced protein expression |
| KR20180069057A (ko) | 2015-10-30 | 2018-06-22 | 다니스코 유에스 인크. | 향상된 단백질 발현 및 이의 방법 |
| JP2018537130A (ja) * | 2015-12-14 | 2018-12-20 | ビーエーエスエフ ソシエタス・ヨーロピアBasf Se | バチルス由来の改変双方向性カタラーゼプロモーター |
| DK3380496T3 (da) | 2015-12-23 | 2020-08-24 | Danisco Us Inc | Forbedret proteinproduktion og fremgangsmåder hertil |
| FI3419991T3 (fi) * | 2016-03-04 | 2023-01-31 | Modifioidut ribosomaaliset promoottorit proteiinien tuottamiseksi mikro-organismeissa | |
| MX2018015559A (es) | 2016-06-17 | 2019-06-06 | Danisco Us Inc | Variantes de proteasa y sus usos. |
| US20200392477A1 (en) | 2016-12-21 | 2020-12-17 | Danisco Us Inc. | Protease variants and uses thereof |
| EP3559226B1 (en) | 2016-12-21 | 2023-01-04 | Danisco US Inc. | Bacillus gibsonii-clade serine proteases |
| WO2018118815A1 (en) | 2016-12-21 | 2018-06-28 | Dupont Nutrition Biosciences Aps | Methods of using thermostable serine proteases |
| DK3571217T5 (da) | 2017-01-23 | 2024-09-02 | Danisco Us Inc | Fremgangsmåder og sammensætninger til opnåelse af naturlig kompetence i bacillus-værtsceller |
| JP7231228B2 (ja) | 2017-02-24 | 2023-03-01 | ダニスコ・ユーエス・インク | バチルス・リケニフォルミスにおける増加したタンパク質産生のための組成物及び方法 |
| EP3583210B1 (en) | 2017-03-15 | 2021-07-07 | Danisco US Inc. | Trypsin-like serine proteases and uses thereof |
| CN110603323A (zh) | 2017-03-15 | 2019-12-20 | 杜邦营养生物科学有限公司 | 使用古细菌丝氨酸蛋白酶的方法 |
| CN110621777A (zh) | 2017-03-15 | 2019-12-27 | 杜邦营养生物科学有限公司 | 胰蛋白酶样丝氨酸蛋白酶及其用途 |
| DK3607097T3 (da) | 2017-04-07 | 2023-09-18 | Dupont Nutrition Biosci Aps | Bacillus-værtsceller, der danner beta-galactosidaser og lactaser i fravær af p-nitrobenzylesterase-sideaktivitet |
| CN111094576A (zh) | 2017-09-13 | 2020-05-01 | 丹尼斯科美国公司 | 用于增加芽胞杆菌属中蛋白质产生的经修饰的5′-非翻译区(utr)序列 |
| US20200354708A1 (en) | 2017-11-29 | 2020-11-12 | Danisco Us Inc. | Subtilisin variants having improved stability |
| WO2019135868A1 (en) | 2018-01-03 | 2019-07-11 | Danisco Us Inc | Mutant and genetically modified bacillus cells and methods thereof for increased protein production |
| CN110004166A (zh) * | 2018-01-05 | 2019-07-12 | 中国科学院天津工业生物技术研究所 | 高效表达分泌β-甘露聚糖酶的重组枯草芽孢杆菌菌株及其获得方法 |
| CN108441489B (zh) * | 2018-04-09 | 2023-04-14 | 潍坊康地恩生物科技有限公司 | 一种蛋白生产方法及高产碱性蛋白酶的枯草芽孢杆菌 |
| EP3799601A1 (en) | 2018-06-19 | 2021-04-07 | Danisco US Inc. | Subtilisin variants |
| EP3810767A1 (en) | 2018-06-19 | 2021-04-28 | Danisco US Inc. | Subtilisin variants |
| EP3818154A1 (en) | 2018-07-06 | 2021-05-12 | DuPont Nutrition Biosciences ApS | Xylanase-containing feed additives for cereal-based animal feed |
| KR20210096629A (ko) * | 2018-11-28 | 2021-08-05 | 다니스코 유에스 인크. | 바실러스 세포에서의 향상된 단백질 생산을 위한 신규 프로모터 서열 및 이의 방법 |
| CA3136114A1 (en) | 2019-04-05 | 2020-10-08 | Danisco Us Inc. | Methods for integrating a donor dna sequence into the genome of bacillus using linear recombinant dna constructs and compositions thereof |
| EP3947656A1 (en) | 2019-04-05 | 2022-02-09 | Danisco US Inc. | Methods for polynucleotide integration into the genome of bacillus using dual circular recombinant dna constructs and compositions thereof |
| CN111944808B (zh) * | 2019-05-16 | 2025-04-29 | 武汉合生科技有限公司 | 核糖体rna启动子在强启动表达非rna基因中的用途 |
| US20220389474A1 (en) | 2019-10-28 | 2022-12-08 | Danisco Us Inc. | Microbial host cells for the production of heterologous cyanuric acid hydrolases and biuret hydrolases |
| US20220389459A1 (en) | 2019-11-19 | 2022-12-08 | Danisco Us Inc. | Selection marker free methods for modifying the genome of bacillus and compositions thereof |
| MX2022008144A (es) * | 2019-12-31 | 2022-08-17 | Air Protein Inc | Composiciones alimenticias con alto contenido de proteinas. |
| KR20220127844A (ko) | 2020-01-15 | 2022-09-20 | 다니스코 유에스 인크. | 바실러스 리체니포르미스에서 단백질 생산을 향상시키기 위한 조성물 및 방법 |
| US20250311734A1 (en) | 2022-05-14 | 2025-10-09 | Novozymes A/S | Compositions and Methods for Preventing, Treating, Suppressing and/or Eliminatting Phytopathogenic Infestations and Infections |
| KR20250054813A (ko) * | 2022-09-02 | 2025-04-23 | 다니스코 유에스 인크. | 그람 양성 세포에서 단백질 생산을 향상시키는 신규한 프로모터 및 5'-비번역 영역 돌연변이 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4760025A (en) | 1984-05-29 | 1988-07-26 | Genencor, Inc. | Modified enzymes and methods for making same |
| US5182204A (en) | 1984-05-29 | 1993-01-26 | Genencor International, Inc. | Non-human carbonyl hydrolase mutants, vectors encoding same and hosts transformed with said vectors |
| US5264366A (en) | 1984-05-29 | 1993-11-23 | Genencor, Inc. | Protease deficient bacillus |
| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5364770A (en) | 1985-08-29 | 1994-11-15 | Genencor International Inc. | Heterologous polypeptides expressed in aspergillus |
| FR2625295B1 (fr) | 1987-12-24 | 1990-04-13 | Gaz De France | Procede et appareil destines a assurer la combustion etagee d'un melange combustible-comburant diminuant la production d'oxydes d'azote |
| EP0351029B1 (en) | 1988-07-15 | 2002-03-06 | Genencor International, Inc. | Novel glucose isomerase enzymes and their use |
| EP1225227B1 (en) | 1990-12-10 | 2009-02-18 | Genencor International, Inc. | Improved saccharification of cellulose by cloning and amplification of the beta-glucosidase gene of trichoderma reesei |
| EP1559776A3 (en) | 1994-06-30 | 2006-01-11 | Novozymes Biotech, Inc. | Non-toxic, non-toxigenic, non-pathogenic Fusarium expression system and promoters and terminators for use therein |
| JP4307563B2 (ja) | 1997-04-07 | 2009-08-05 | ユニリーバー・ナームローゼ・ベンノートシャープ | 糸状菌、特にアスペルギルス属に属する糸状菌のアグロバクテリウム媒介性形質転換 |
| AR015977A1 (es) | 1997-10-23 | 2001-05-30 | Genencor Int | Variantes de proteasa multiplemente substituida con carga neta alterada para su empleo en detergentes |
| US6287839B1 (en) | 1997-11-19 | 2001-09-11 | Genencor International, Inc. | Cellulase producing actinomycetes, cellulase produced therefrom and method of producing same |
| US6562612B2 (en) | 1997-11-19 | 2003-05-13 | Genencor International, Inc. | Cellulase producing actinomycetes, cellulase produced therefrom and method of producing same |
| US7718411B1 (en) | 2004-08-05 | 2010-05-18 | Danisco Us Inc. | Trichoderma reesei G/11 xylanases with improved stability |
| FI108728B (fi) | 1999-10-12 | 2002-03-15 | Carbozyme Oy | Menetelmä perheen G/11 ksylanaasien stabiilisuuden parantamiseksi ja optimaalisen pH-alueen muuttamiseksi |
| US6509185B1 (en) | 2000-01-07 | 2003-01-21 | Genencor International, Inc. | Mutant aprE promotor |
| CA2481414C (en) | 2002-04-22 | 2013-04-09 | E.I. Du Pont De Nemours And Company | Promoter and plasmid system for genetic engineering |
| GB0422052D0 (en) | 2004-10-04 | 2004-11-03 | Dansico As | Enzymes |
| AU2005290934C1 (en) | 2004-10-04 | 2013-05-09 | Dupont Nutrition Biosciences Aps | Citrobacter freundii phytase and homologues |
| GB0423139D0 (en) | 2004-10-18 | 2004-11-17 | Danisco | Enzymes |
| CA2676649C (en) | 2007-01-30 | 2016-08-30 | Novozymes A/S | Polypeptides having phytase activty and polynucleotides encoding same |
| MX301786B (es) | 2007-02-07 | 2012-07-27 | Danisco Us Inc Genencor Div | Fitasas variantes de buttiauxella sp. que tienen propiedades alteradas. |
| WO2008148575A2 (en) * | 2007-06-07 | 2008-12-11 | Dsm Ip Assets B.V. | Increased production of a target product via stabilization of mrna |
| DK3323889T3 (da) | 2007-11-20 | 2020-06-29 | Danisco Us Inc | Glucoamylasevarianter med ændrede egenskaber |
| EP2283124B1 (en) | 2008-04-18 | 2016-05-25 | Danisco US Inc. | Buttiauxella sp. phytase variants |
| DK2297312T3 (da) | 2008-06-06 | 2013-12-16 | Danisco Us Inc | Alpha-amylasevarianter af Bacillus subtilis og fremgangsmåder til anvendelse heraf |
| CN102057040A (zh) | 2008-06-06 | 2011-05-11 | 丹尼斯科美国公司 | 具有改良特性的嗜热脂肪土芽孢杆菌α-淀粉酶(AMYS)变体 |
| BRPI0920925A2 (pt) | 2008-11-11 | 2015-08-18 | Danisco Us Inc | Composições e métodos compreendendo uma variante de subtilisina |
| GB0922467D0 (en) | 2009-04-24 | 2010-02-03 | Danisco | Feed supplement |
| DK2421973T3 (en) | 2009-04-24 | 2018-07-30 | Danisco Us Inc | PROTEAS WITH MODIFIED PRO AREAS |
| AR076941A1 (es) * | 2009-06-11 | 2011-07-20 | Danisco Us Inc | Cepa de bacillus para una mayor produccion de proteina |
| CN102575242B (zh) | 2009-07-31 | 2015-03-25 | 丹尼斯科美国公司 | 具有经修饰的前原区域的蛋白酶 |
-
2012
- 2012-12-06 DK DK12806777.4T patent/DK2788491T3/en active
- 2012-12-06 WO PCT/US2012/068285 patent/WO2013086219A1/en not_active Ceased
- 2012-12-06 JP JP2014546087A patent/JP6378089B2/ja active Active
- 2012-12-06 US US14/364,016 patent/US20140329309A1/en not_active Abandoned
- 2012-12-06 EP EP12806777.4A patent/EP2788491B1/en active Active
- 2012-12-06 CN CN201280059922.9A patent/CN104053780A/zh active Pending
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