JP2015213501A5 - - Google Patents
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- JP2015213501A5 JP2015213501A5 JP2015088066A JP2015088066A JP2015213501A5 JP 2015213501 A5 JP2015213501 A5 JP 2015213501A5 JP 2015088066 A JP2015088066 A JP 2015088066A JP 2015088066 A JP2015088066 A JP 2015088066A JP 2015213501 A5 JP2015213501 A5 JP 2015213501A5
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- JP
- Japan
- Prior art keywords
- composition
- composition according
- individual
- functional
- acid bacterium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000203 mixture Substances 0.000 claims 16
- 241000894006 Bacteria Species 0.000 claims 6
- 206010071275 Functional gastrointestinal disease Diseases 0.000 claims 4
- 208000002551 Irritable Bowel Syndrome Diseases 0.000 claims 4
- 239000002253 acid Substances 0.000 claims 4
- 208000004998 Abdominal Pain Diseases 0.000 claims 3
- 206010010774 Constipation Diseases 0.000 claims 3
- 206010003591 Ataxia Diseases 0.000 claims 2
- 206010020751 Hypersensitivity Diseases 0.000 claims 2
- 206010037175 Psychiatric disease Diseases 0.000 claims 2
- 201000005794 allergic hypersensitivity disease Diseases 0.000 claims 2
- 239000000090 biomarker Substances 0.000 claims 2
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 claims 2
- 230000009610 hypersensitivity Effects 0.000 claims 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 2
- 235000014655 lactic acid Nutrition 0.000 claims 2
- 239000004310 lactic acid Substances 0.000 claims 2
- 239000002858 neurotransmitter agent Substances 0.000 claims 2
- ADNPLDHMAVUMIW-CUZNLEPHSA-N (2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-N-[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-y Chemical group C([C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)CCCN=C(N)N)C1=CC=CC=C1 ADNPLDHMAVUMIW-CUZNLEPHSA-N 0.000 claims 1
- 206010002855 Anxiety Diseases 0.000 claims 1
- 206010057666 Anxiety disease Diseases 0.000 claims 1
- OMFXVFTZEKFJBZ-HJTSIMOOSA-N Corticosterone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@H](CC4)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OMFXVFTZEKFJBZ-HJTSIMOOSA-N 0.000 claims 1
- 206010012735 Diarrhoea Diseases 0.000 claims 1
- 240000006024 Lactobacillus plantarum Species 0.000 claims 1
- 229940072205 Lactobacillus plantarum Drugs 0.000 claims 1
- 235000013965 Lactobacillus plantarum Nutrition 0.000 claims 1
- 208000002193 Pain Diseases 0.000 claims 1
- 210000002966 Serum Anatomy 0.000 claims 1
- 102100002996 TAC1 Human genes 0.000 claims 1
- 101700065588 TAC1 Proteins 0.000 claims 1
- 230000036506 anxiety Effects 0.000 claims 1
- 239000000969 carrier Substances 0.000 claims 1
- 238000004113 cell culture Methods 0.000 claims 1
- 229960003638 dopamine Drugs 0.000 claims 1
- 201000006549 dyspepsia Diseases 0.000 claims 1
- 201000000117 functional diarrhea Diseases 0.000 claims 1
- 230000000813 microbial Effects 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 230000035807 sensation Effects 0.000 claims 1
Claims (17)
- 登録番号ＤＳＭ ２８６３２でドイツ微生物細胞培養コレクション（ＤＳＭＺ）に寄託しているラクトバチルス・プランタルム亜種プランタルム（Ｌａｃｔｏｂａｃｉｌｌｕｓ ｐｌａｎｔａｒｕｍ ｓｕｂｓｐ． ｐｌａｎｔａｒｕｍ）ＰＳ１２８である単離乳酸菌。
- 請求項１に記載の単離乳酸菌と、担体とを含む組成物。
- 請求項１に記載の単離乳酸菌を含む、個体のストレス誘発失調または精神障害を予防または治療するための組成物。
- ストレス誘発失調または精神障害が不安、憂うつ及び過敏性腸症候群からなる群から選ばれる、請求項３に記載の組成物。
- 血清コルチコステロン濃度が個体において統計学的に有意に低下する、請求項３または４に記載の組成物。
- 神経伝達物質の濃度が個体において統計学的に有意に上昇する、請求項３または４に記載の組成物。
- 神経伝達物質がドーパミンである請求項６に記載の組成物。
- 請求項１に記載の単離乳酸菌を含む、個体の機能性胃腸障害を予防または治療するための組成物。
- 請求項１に記載の単離乳酸菌を含む、個体の内臓過敏を予防または治療するための組成物。
- 内臓過敏が機能性胃腸障害に関連する、請求項９に記載の組成物。
- 機能性胃腸障害が機能性腹痛、過敏性腸症候群、便秘、機能性下痢と機能性消化不良からなる群から選ばれる、請求項８または１０に記載の組成物。
- 機能性胃腸障害が、機能性腹痛、過敏性腸症候群または便秘である、請求項１１に記載の組成物。
- 請求項１に記載の単離乳酸菌を含む、個体の機能性腹痛、過敏性腸症候群または便秘を予防または治療するための組成物。
- 痛覚のバイオマーカーレベルが個体において統計学的に有意に低下する、請求項８〜１３のいずれか１項に記載の組成物。
- バイオマーカーがＰ物質である、請求項１４に記載の組成物。
- 個体の筋電図信号が統計学的に有意に低下する、請求項８〜１３のいずれか１項に記載の組成物。
- 経口投与用である、請求項３〜１６のいずれか１項に記載の組成物。
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14/259,442 US10967013B2 (en) | 2014-04-23 | 2014-04-23 | Lactic acid bacterium for prophylaxis or treatment of a stress-induced disorder and a composition containing the same |
| US14/259,442 | 2014-04-23 | ||
| US14/690,502 US10188684B2 (en) | 2015-04-20 | 2015-04-20 | Method for preventing or treating functional gastrointestinal disorder by lactic acid bacterium |
| US14/690,502 | 2015-04-20 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015213501A JP2015213501A (ja) | 2015-12-03 |
| JP2015213501A5 true JP2015213501A5 (ja) | 2016-01-28 |
| JP6035578B2 JP6035578B2 (ja) | 2016-11-30 |
Family
ID=53008330
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015088066A Active JP6035578B2 (ja) | 2014-04-23 | 2015-04-23 | 乳酸菌、それを含む組成物及びそれらの使用 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP2937424B1 (ja) |
| JP (1) | JP6035578B2 (ja) |
| CN (1) | CN105002109B (ja) |
| ES (1) | ES2624673T3 (ja) |
| PL (1) | PL2937424T3 (ja) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6933358B2 (ja) * | 2016-04-06 | 2021-09-08 | 東海漬物株式会社 | 美肌促進剤 |
| CN110023485B (zh) * | 2016-07-19 | 2023-12-05 | 益福生医股份有限公司 | 利用乳酸菌预防或治疗运动障碍的方法 |
| KR20180019474A (ko) * | 2016-08-16 | 2018-02-26 | 주식회사 엠디헬스케어 | 락토바실러스 플란타룸 유래 소포를 포함하는 정신질환 예방 또는 치료용 조성물 |
| CN107050062A (zh) * | 2016-11-08 | 2017-08-18 | 江西益盟科技有限公司 | 治疗便秘的乳酸菌组合物及其制备方法 |
| EP3568460A4 (en) * | 2017-01-13 | 2020-09-23 | Bened Biomedical Co., Ltd. | NOVEL LACTIC ACID BACTERIA AND THEIR APPLICATIONS |
| KR102089836B1 (ko) * | 2017-03-15 | 2020-03-16 | (주)바이오일레븐 | 트립토판분해효소 음성균과 인터페론 감마 형성을 유도하는 균주를 이용한 염증성 질환 예방 및 치료용 약학적 조성물 또는 이를 이용한 치료방법 |
| CN106906165B (zh) * | 2017-04-25 | 2020-07-24 | 重庆第二师范学院 | 一种植物乳杆菌及其在制备预防便秘的食品中的应用 |
| CN107267416A (zh) * | 2017-07-05 | 2017-10-20 | 重庆第二师范学院 | 植物乳杆菌ys2及其在制备预防便秘的食品中的应用 |
| WO2019119261A1 (en) * | 2017-12-19 | 2019-06-27 | Dupont Nutrition Biosciences Aps | Probiotics for cognitive and mental health |
| KR20200112840A (ko) * | 2017-12-19 | 2020-10-05 | 듀폰 뉴트리션 바이오사이언시즈 에이피에스 | 인지 및 정신 건강을 위한 프로바이오틱스 |
| RU2764639C1 (ru) | 2018-02-02 | 2022-01-19 | Кобиолабс, Инк. | Штамм kbl396 lactobacillus plantarum и его применение |
| CN111035661A (zh) * | 2018-10-15 | 2020-04-21 | 深圳市华大农业应用研究院 | 植物乳杆菌的用途 |
| TWI731279B (zh) | 2018-11-21 | 2021-06-21 | 葡萄王生技股份有限公司 | 發酵乳桿菌gkf3、含其之組合物及改善精神失調之用途 |
| ES2763350B2 (es) * | 2018-11-28 | 2020-10-13 | Consejo Superior Investigacion | Cepa de christensenella minuta y uso de la misma |
| BR112021010794A2 (pt) * | 2018-12-06 | 2021-08-31 | Dupont Nutrition Biosciences Aps | Probióticos para a saúde cognitiva e mental |
| WO2020156417A1 (en) * | 2019-01-28 | 2020-08-06 | Bened Biomedical Co., Ltd. | Method for protecting a subject for exercise |
| CN113473998A (zh) * | 2019-02-01 | 2021-10-01 | 农业食品和环境国家研究中心 | 用于预防和/或治疗内脏痛的乳酸乳球菌菌株 |
| BR112021014935A2 (pt) * | 2019-02-01 | 2021-09-28 | Bened Biomedical Co., Ltd. | Método para prevenir ou tratar uma emoção ou comportamento anormal em um animal não humano por meio de bactéria ácido-láctica |
| KR102148707B1 (ko) * | 2019-02-22 | 2020-08-31 | 한국식품연구원 | 우울증 및 불안장애의 예방, 개선 또는 치료 효능을 갖는 김치 유산균 락토바실러스 사케아이 |
| US20230035928A1 (en) * | 2020-02-06 | 2023-02-02 | Wang-Tso Lee | Composition of lactic acid bacterium for use in preventing or treating rett syndrome |
| WO2022083754A1 (en) * | 2020-10-22 | 2022-04-28 | Lee Wang Tso | Lactic acid bacterium for treatment of aromatic l-amino acid decarboxylase deficiency |
| WO2022131192A1 (ja) * | 2020-12-16 | 2022-06-23 | 株式会社明治 | 脳組織の炎症改善用組成物 |
| CN113215018A (zh) * | 2021-02-04 | 2021-08-06 | 郑州大学 | 一株植物乳杆菌植物亚种及其在豆粕和北艾混合发酵中的应用 |
| CN113564084A (zh) * | 2021-08-13 | 2021-10-29 | 华东理工大学 | 植物乳杆菌x7022在预防和治疗便秘上的应用 |
| TWI810645B (zh) * | 2021-09-06 | 2023-08-01 | 景岳生物科技股份有限公司 | 乳桿菌組合物及其改善抗生素造成之焦慮症的用途 |
| WO2024089260A1 (en) * | 2022-10-28 | 2024-05-02 | Chr. Hansen A/S | Lactiplantibacillus plantarum for use in addressing the symptoms of irritable bowel syndrome |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5725853A (en) * | 1994-10-18 | 1998-03-10 | Pioneer Hi-Bred International, Inc. | 4 strain direct-fed microbial |
| US20050158294A1 (en) * | 2003-12-19 | 2005-07-21 | The Procter & Gamble Company | Canine probiotic Bifidobacteria pseudolongum |
| EP2332539A4 (en) * | 2008-08-21 | 2012-05-09 | Suntory Holdings Ltd | PHARMACEUTICAL PREPARATION, FOOD OR BEVERAGE WITH ANTICIPATIVE EFFECT ON THE SEROTONINE TRANSPORTER |
-
2015
- 2015-04-23 ES ES15164896.1T patent/ES2624673T3/es active Active
- 2015-04-23 JP JP2015088066A patent/JP6035578B2/ja active Active
- 2015-04-23 CN CN201510195767.9A patent/CN105002109B/zh active Active
- 2015-04-23 EP EP15164896.1A patent/EP2937424B1/en active Active
- 2015-04-23 PL PL15164896T patent/PL2937424T3/pl unknown
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