JP2015083582A5 - - Google Patents
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- Publication number
- JP2015083582A5 JP2015083582A5 JP2014247793A JP2014247793A JP2015083582A5 JP 2015083582 A5 JP2015083582 A5 JP 2015083582A5 JP 2014247793 A JP2014247793 A JP 2014247793A JP 2014247793 A JP2014247793 A JP 2014247793A JP 2015083582 A5 JP2015083582 A5 JP 2015083582A5
- Authority
- JP
- Japan
- Prior art keywords
- suspension
- less
- volume
- suspension according
- gauge needle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000725 suspension Substances 0.000 claims 6
- 239000002245 particle Substances 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 238000007920 subcutaneous administration Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11508008P | 2008-11-16 | 2008-11-16 | |
| US61/115,080 | 2008-11-16 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011536414A Division JP5711138B2 (ja) | 2008-11-16 | 2009-11-10 | 高濃度の低粘度懸濁液 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015083582A JP2015083582A (ja) | 2015-04-30 |
| JP2015083582A5 true JP2015083582A5 (enExample) | 2015-07-02 |
Family
ID=42170660
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011536414A Expired - Fee Related JP5711138B2 (ja) | 2008-11-16 | 2009-11-10 | 高濃度の低粘度懸濁液 |
| JP2014247793A Pending JP2015083582A (ja) | 2008-11-16 | 2014-12-08 | 高濃度の低粘度懸濁液 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011536414A Expired - Fee Related JP5711138B2 (ja) | 2008-11-16 | 2009-11-10 | 高濃度の低粘度懸濁液 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US8779094B2 (enExample) |
| EP (1) | EP2376522A4 (enExample) |
| JP (2) | JP5711138B2 (enExample) |
| KR (1) | KR20110103961A (enExample) |
| CA (1) | CA2743789C (enExample) |
| IL (1) | IL212919A (enExample) |
| WO (1) | WO2010056657A2 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2717154T3 (es) | 2007-06-22 | 2019-06-19 | Univ Texas | Formación de partículas de péptido o proteína submicrométricas estables mediante congelación de película fina |
| US9072668B2 (en) | 2010-03-09 | 2015-07-07 | Janssen Biotech, Inc. | Non-aqueous high concentration reduced viscosity suspension formulations of antibodies |
| US20110223208A1 (en) * | 2010-03-09 | 2011-09-15 | Beth Hill | Non-Aqueous High Concentration Reduced Viscosity Suspension Formulations |
| CN103096934A (zh) * | 2010-03-09 | 2013-05-08 | 詹森生物科技公司 | 非水性高浓度低粘度混悬剂 |
| US9445990B2 (en) * | 2010-10-06 | 2016-09-20 | Medtronic, Inc. | TNF inhibitor formulation for use in implantable infusion devices |
| US20120230913A1 (en) * | 2011-03-10 | 2012-09-13 | Board Of Regents, The University Of Texas System | Protein nanoparticle dispersions |
| AU2012328524B2 (en) * | 2011-10-28 | 2017-05-18 | Excelse Bio, Inc. | Protein formulations containing amino acids |
| EP3854433A3 (en) | 2011-11-07 | 2021-10-27 | Battelle Memorial Institute | Processes for delivery of viscous drug therapies |
| NZ701915A (en) * | 2012-05-18 | 2016-11-25 | Genentech Inc | High-concentration monoclonal antibody formulations |
| HK1220120A1 (zh) * | 2013-03-15 | 2017-04-28 | Ansun Biopharma, Inc. | 制造注射蛋白质微粒悬浮液的方法 |
| IL312865B2 (en) | 2013-09-11 | 2025-06-01 | Eagle Biologics Inc | Liquid protein formulations containing viscosity-lowering agents |
| CN103976947B (zh) * | 2014-06-05 | 2016-08-17 | 段明星 | 一种含酶油悬浮剂及其制备方法与应用 |
| WO2016054259A1 (en) * | 2014-10-01 | 2016-04-07 | Arsia Therapeutics, Inc. | Polysaccharide and nucleic acid formulations containing viscosity-lowering agents |
| JP5774190B1 (ja) * | 2014-12-12 | 2015-09-09 | ジーンメディカル株式会社 | 皮下注射用剤及び皮下注射用剤を含有する注射器の製造方法 |
| KR102496871B1 (ko) * | 2014-12-12 | 2023-02-07 | 주식회사 모테조 | 피하 주사용제 |
| EP3522918A1 (en) * | 2016-10-06 | 2019-08-14 | Amgen Inc. | Reduced viscosity protein pharmaceutical formulations |
| AU2017364077A1 (en) | 2016-11-22 | 2019-06-20 | Elektrofi, Inc. | Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof |
| WO2019023392A1 (en) | 2017-07-25 | 2019-01-31 | Elektrofi, Inc. | FORMATION OF PARTICLES COMPRISING AGENTS |
| US12115262B2 (en) | 2018-05-24 | 2024-10-15 | Elektrofi, Inc. | Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof |
| KR102051808B1 (ko) | 2018-07-23 | 2019-12-04 | 주식회사 종근당 | 테스토스테론 운데카노에이트를 포함하는 안정한 약제학적 조성물 |
| EP3917500A2 (en) | 2019-01-31 | 2021-12-08 | Elektrofi, Inc. | Particle formation and morphology |
| SG11202107901QA (en) | 2019-02-05 | 2021-08-30 | Lindy Biosciences Inc | Isolated cell culture components and methods for isolating the same from liquid cell culture medium |
| US20200376128A1 (en) * | 2019-06-01 | 2020-12-03 | Lupin Holdings B.V. | Monodisperse resorbable polyester polymer compositions, systems, and methods |
| JP7781743B2 (ja) * | 2019-09-13 | 2025-12-08 | エレクトロフィ,インコーポレイテッド | 疾患の処置のための治療用生物学的作用剤の送達のための組成物及び方法 |
| AU2021257476A1 (en) | 2020-04-17 | 2022-11-03 | Elektrofi, Inc. | Methods of forming particles by continuous droplet formation and dehydration |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE795516A (fr) | 1972-02-17 | 1973-08-16 | Ciba Geigy | Preparations de peptides huileuses et injectables et procede pour leur preparation |
| US4310516A (en) | 1980-02-01 | 1982-01-12 | Block Drug Company Inc. | Cosmetic and pharmaceutical vehicle thickened with solid emulsifier |
| EP0079143A3 (en) | 1981-10-20 | 1984-11-21 | Adnovum Ag | Pseudoplastic gel transfer |
| US4594108A (en) | 1983-09-19 | 1986-06-10 | The Dow Chemical Company | Highly pseudoplastic polymer solutions |
| US5411951A (en) | 1984-10-04 | 1995-05-02 | Monsanto Company | Prolonged release of biologically active somatotropin |
| US5288479A (en) | 1989-01-17 | 1994-02-22 | Sterling Drug, Inc. | Extrudable elastic oral pharmaceutical gel compositions and metered dose dispensers containing them and method of making and method of use thereof |
| SE465950B (sv) | 1989-10-23 | 1991-11-25 | Medinvent Sa | Kombination av ett aggregat partikelformat, kristallint eller frystorkat laekemedel med en pseudoplastisk gel foer beredning av ett injicerbart preparat samt foerfarande foer dess framstaellning |
| US5300302A (en) | 1990-10-04 | 1994-04-05 | Nestec S.A. | Pharmaceutical composition in gel form in a dispensing package |
| YU87892A (sh) | 1991-10-01 | 1995-12-04 | Eli Lilly And Company Lilly Corporate Center | Injektibilne formulacije produženog otpuštanja i postupci za njihovo dobijanje i primenu |
| WO1993019739A1 (en) | 1992-03-30 | 1993-10-14 | Alza Corporation | Viscous suspensions of controlled-release drug particles |
| US5571525A (en) | 1992-03-30 | 1996-11-05 | Alza Corporation | Erosion rate modifier for use in bioerodible drug delivery devices and method of use |
| US5512293A (en) | 1992-07-23 | 1996-04-30 | Alza Corporation | Oral sustained release drug delivery device |
| SE9203594D0 (sv) | 1992-11-30 | 1992-11-30 | Christer Nystroem | Laekemedel i dispersa system |
| DK0768867T3 (da) | 1994-06-13 | 2002-10-28 | Alza Corp | Doseringsform til indgivelse af lægemiddel i væskeformig formulering |
| US5904935A (en) | 1995-06-07 | 1999-05-18 | Alza Corporation | Peptide/protein suspending formulations |
| US6267958B1 (en) | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
| US5932547A (en) | 1996-07-03 | 1999-08-03 | Alza Corporation | Non-aqueous polar aprotic peptide formulations |
| NZ333580A (en) | 1996-07-03 | 2000-06-23 | Alza Corp | Non-Aqueous protic peptide formulations, preferably LHRH |
| US5916582A (en) | 1996-07-03 | 1999-06-29 | Alza Corporation | Aqueous formulations of peptides |
| IN184589B (enExample) | 1996-10-16 | 2000-09-09 | Alza Corp | |
| US7393630B2 (en) | 1997-12-16 | 2008-07-01 | Novartis Vaccines And Diagnostics, Inc. | Use of microparticles combined with submicron oil-in-water emulsions |
| ES2261190T3 (es) | 1999-02-08 | 2006-11-16 | Alza Corporation | Vehiculos viscosos no acuosos estables de fase unica y formulaciones que utilizan dichos vehiculos. |
| US7258869B1 (en) | 1999-02-08 | 2007-08-21 | Alza Corporation | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle |
| FR2809309B1 (fr) * | 2000-05-23 | 2004-06-11 | Mainelab | Microspheres a liberation prolongee pour administration injectable |
| WO2002043580A2 (en) | 2000-10-27 | 2002-06-06 | Epic Therapeutics, Inc. | Production of microspheres |
| US20040022861A1 (en) * | 2001-01-30 | 2004-02-05 | Williams Robert O. | Process for production of nanoparticles and microparticles by spray freezing into liquid |
| WO2002067991A1 (en) * | 2001-02-23 | 2002-09-06 | Genentech, Inc. | Erodible polymers for injection |
| EP1492554B1 (en) * | 2001-06-21 | 2019-08-21 | Althea Technologies, Inc. | Spherical protein particles |
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| RU2332986C2 (ru) * | 2003-04-04 | 2008-09-10 | Дженентек, Инк. | Высококонцентрированные композиции антител и белков |
| CA2540695A1 (en) * | 2003-06-24 | 2004-12-29 | Baxter International Inc. | Specific delivery of drugs to the brain |
| EP1646445A4 (en) | 2003-07-18 | 2007-09-19 | Baxter Int | METHOD OF MANUFACTURING, USING AND COMPOSING SMALL BALLULAR PARTICLES PRODUCED BY CONTROLLED PHASE SEPARATION |
| FR2862536B1 (fr) * | 2003-11-21 | 2007-11-23 | Flamel Tech Sa | Formulations pharmaceutiques pour la liberation prolongee de principe(s) actif(s), ainsi que leurs applications notamment therapeutiques |
| US8333995B2 (en) | 2004-05-12 | 2012-12-18 | Baxter International, Inc. | Protein microspheres having injectable properties at high concentrations |
| US8728525B2 (en) | 2004-05-12 | 2014-05-20 | Baxter International Inc. | Protein microspheres retaining pharmacokinetic and pharmacodynamic properties |
| US20060141040A1 (en) * | 2004-12-23 | 2006-06-29 | Guohua Chen | Injectable non-aqueous suspension |
| WO2006083761A2 (en) * | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
| US20070015689A1 (en) | 2005-06-23 | 2007-01-18 | Alza Corporation | Complexation of metal ions with polypeptides |
| EP1968550A2 (en) | 2005-12-16 | 2008-09-17 | University Of Kansas | Nanoclusters for delivery of therapeutics |
| WO2007072982A1 (en) | 2005-12-20 | 2007-06-28 | Fujifilm Corporation | Protein nanoparticles and the use of the same |
| US20080102128A1 (en) * | 2006-07-28 | 2008-05-01 | Flamel Technologies, Inc. | Modified-release microparticles based on amphiphilic copolymer and on active principles(s) and pharmaceutical formulations comprising them |
| ES2717154T3 (es) * | 2007-06-22 | 2019-06-19 | Univ Texas | Formación de partículas de péptido o proteína submicrométricas estables mediante congelación de película fina |
| CN101081882A (zh) * | 2007-07-06 | 2007-12-05 | 天津大学 | 大分子印迹交联聚乙烯基吡咯烷酮微球及低温悬浮聚合制备方法 |
| JP2009173610A (ja) | 2008-01-28 | 2009-08-06 | Fujifilm Corp | タンパク質ナノ粒子 |
| EP2259798B1 (en) | 2008-03-05 | 2013-12-11 | Baxter International Inc. | Surface-modified particles and methods for targeted drug delivery |
| BRPI0908686B8 (pt) | 2008-05-09 | 2021-05-25 | South Dakota State Univ | método de produção de nanopartículas não-imunogênicas, nanopartícula não-imunogênica terapeuticamente ativa, composição terapêutica, uso de uma nanopartícula não-imunogênica e kit para a produção de nanopartículas não-imunogênicas |
| US20100009007A1 (en) | 2008-07-10 | 2010-01-14 | Baxter International Inc. | Non-covalent modification of microparticles and process of preparing same |
| US8323685B2 (en) | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing compositions containing microparticles |
| AR075715A1 (es) | 2009-03-05 | 2011-04-20 | Novartis Ag | Formulacion de anticuerpo liofilizado |
-
2009
- 2009-11-10 US US13/129,283 patent/US8779094B2/en active Active
- 2009-11-10 JP JP2011536414A patent/JP5711138B2/ja not_active Expired - Fee Related
- 2009-11-10 CA CA2743789A patent/CA2743789C/en active Active
- 2009-11-10 KR KR1020117013867A patent/KR20110103961A/ko not_active Withdrawn
- 2009-11-10 EP EP09826617.4A patent/EP2376522A4/en not_active Withdrawn
- 2009-11-10 WO PCT/US2009/063852 patent/WO2010056657A2/en not_active Ceased
-
2011
- 2011-05-16 IL IL212919A patent/IL212919A/en active IP Right Grant
-
2014
- 2014-06-05 US US14/297,403 patent/US20140378370A1/en not_active Abandoned
- 2014-12-08 JP JP2014247793A patent/JP2015083582A/ja active Pending
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