JP2016540030A5 - - Google Patents
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- Publication number
- JP2016540030A5 JP2016540030A5 JP2016540981A JP2016540981A JP2016540030A5 JP 2016540030 A5 JP2016540030 A5 JP 2016540030A5 JP 2016540981 A JP2016540981 A JP 2016540981A JP 2016540981 A JP2016540981 A JP 2016540981A JP 2016540030 A5 JP2016540030 A5 JP 2016540030A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- vortioxetine
- nalmefene
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000003839 salts Chemical class 0.000 claims 20
- WJBLNOPPDWQMCH-MBPVOVBZSA-N Nalmefene Chemical compound N1([C@@H]2CC3=CC=C(C=4O[C@@H]5[C@](C3=4)([C@]2(CCC5=C)O)CC1)O)CC1CC1 WJBLNOPPDWQMCH-MBPVOVBZSA-N 0.000 claims 10
- 229960005297 nalmefene Drugs 0.000 claims 10
- YQNWZWMKLDQSAC-UHFFFAOYSA-N vortioxetine Chemical compound CC1=CC(C)=CC=C1SC1=CC=CC=C1N1CCNCC1 YQNWZWMKLDQSAC-UHFFFAOYSA-N 0.000 claims 10
- 229960002263 vortioxetine Drugs 0.000 claims 10
- 239000008194 pharmaceutical composition Substances 0.000 claims 9
- 239000000654 additive Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA201300710 | 2013-12-20 | ||
| DKPA201300710 | 2013-12-20 | ||
| DKPA201400590 | 2014-10-16 | ||
| DKPA201400590 | 2014-10-16 | ||
| PCT/EP2014/078515 WO2015091833A1 (en) | 2013-12-20 | 2014-12-18 | Use of an opioid receptor antagonist with kappa-activity and vortioxetine for treatment of depressive disorder with melancholic features |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016540030A JP2016540030A (ja) | 2016-12-22 |
| JP2016540030A5 true JP2016540030A5 (enExample) | 2018-01-18 |
| JP6448645B2 JP6448645B2 (ja) | 2019-01-09 |
Family
ID=52146489
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016540981A Active JP6448645B2 (ja) | 2013-12-20 | 2014-12-18 | メランコリアの特徴を伴う抑うつ障害を処置するための、カッパ−活性を伴うオピオイド受容体拮抗薬およびボルチオキセチンの使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10376506B2 (enExample) |
| EP (1) | EP3082815B1 (enExample) |
| JP (1) | JP6448645B2 (enExample) |
| KR (1) | KR20160093025A (enExample) |
| CN (1) | CN105828821B (enExample) |
| AU (1) | AU2014368548B2 (enExample) |
| CA (1) | CA2933733A1 (enExample) |
| CL (1) | CL2016001570A1 (enExample) |
| ES (1) | ES2694352T3 (enExample) |
| IL (1) | IL246253A0 (enExample) |
| MX (1) | MX368870B (enExample) |
| RU (1) | RU2679661C1 (enExample) |
| SG (1) | SG11201604944PA (enExample) |
| WO (1) | WO2015091833A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20190025556A (ko) * | 2016-07-01 | 2019-03-11 | 하. 룬드벡 아크티에셀스카브 | 항우울 효과의 신속한 개시를 위한 보티옥세틴 투여 요법 |
| US20210393621A1 (en) | 2018-10-26 | 2021-12-23 | The Research Foundation For The State University Of New York | Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia |
| CA3118708A1 (en) | 2018-11-06 | 2020-05-14 | Purdue Pharma L.P. | Compositions and methods for opioid antagonist delivery |
| US11266627B1 (en) | 2021-05-04 | 2022-03-08 | Janssen Pharmaceuticals, Inc. | Compositions and methods for the treatment of depression |
| US12161622B2 (en) | 2021-05-04 | 2024-12-10 | Janssen Pharmaceuticals, Inc. | Compositions and methods for the treatment of depression |
| US11998524B2 (en) | 2022-03-07 | 2024-06-04 | Janssen Pharmaceuticals, Inc. | Forms of aticaprant |
| IL315415A (en) | 2022-03-07 | 2024-11-01 | Janssen Pharmaceuticals Inc | The compositions containing eticarpant |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5028612A (en) | 1990-03-22 | 1991-07-02 | Hillel Glover | Method for treating emotional numbness |
| US5013740A (en) | 1990-03-22 | 1991-05-07 | Hillel Glover | Method for treating emotional numbness and coma |
| US5512593A (en) * | 1993-03-02 | 1996-04-30 | John S. Nagle | Composition and method of treating depression using natoxone or naltrexone in combination with a serotonin reuptake inhibitor |
| EP1353665A4 (en) | 2000-12-21 | 2004-05-06 | Mclean Hospital Corp | Treatment of depression |
| US20030087896A1 (en) | 2001-08-09 | 2003-05-08 | Hillel Glover | Treatment of refractory depression with an opiate antagonist and an antidepressant |
| HUP0401022A3 (en) * | 2001-08-14 | 2006-11-28 | Biotie Therapies Corp | Method for the preparation of pharmaceutical compositions containing opioid antagonist for treating alcoholism or alcohol abuse |
| UA81749C2 (uk) | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
| DK1485051T3 (da) * | 2002-03-20 | 2008-09-08 | Euro Celtique Sa | Fremgangsmåde til indgivelse af buprenorphin til behandling af depression |
| US20080045610A1 (en) * | 2004-09-23 | 2008-02-21 | Alexander Michalow | Methods for regulating neurotransmitter systems by inducing counteradaptations |
| JP2009517393A (ja) * | 2005-11-28 | 2009-04-30 | オレキシジェン・セラピューティクス・インコーポレーテッド | 不安症の治療方法 |
| CN101432011A (zh) * | 2006-02-27 | 2009-05-13 | 亚历山大·米哈洛 | 通过诱导逆适应调节神经递质系统的方法 |
| WO2008066916A1 (en) | 2006-11-30 | 2008-06-05 | The Mclean Hospital Corporation | Methods for the treatment of mood disorders |
| PT2001456E (pt) * | 2006-04-04 | 2010-03-03 | Emodys Gmbh | Utilização de composições contendo antagonistas dos receptores opióides kappa no tratamento de distúrbios dissociativos |
| US20070259939A1 (en) * | 2006-05-04 | 2007-11-08 | Accelerated Technologies | Using naltrexone as a multi-purpose health supplement to improve the human condition and preventing multiple diseases and infirmities by stimulating immune system vitality and robustness |
| CN102614179B (zh) | 2006-06-16 | 2015-11-25 | H.隆德贝克有限公司 | 作为用于治疗认知损伤的、具有结合的对血清素再吸收、5-ht3和5-ht1a活性的化合物的1-[2-(2，4-二甲基苯基硫烷基)-苯基]哌嗪 |
| TW200848411A (en) | 2007-03-20 | 2008-12-16 | Lundbeck & Co As H | Novel therapeutic uses of 1-[2-(2, 4-dimethylphenylsulfanyl)phenyl]-piperazine |
| TW200932233A (en) * | 2007-11-13 | 2009-08-01 | Lundbeck & Co As H | Therapeutic uses of compounds having combined SERT, 5-HT3 and 5-HT1a activity |
| TW200932225A (en) * | 2007-12-14 | 2009-08-01 | Lundbeck & Co As H | 4-[2,3-difluoro-6-(2-fluoro-4-methyl-phenylsulfanyl)-phenyl]-piperidine |
| EA019331B1 (ru) | 2009-05-25 | 2014-02-28 | Х. Лундбекк А/С | Получение налмефена гидрохлорида из налтрексона |
| WO2011020030A2 (en) * | 2009-08-13 | 2011-02-17 | The General Hospital Corporation | Methods and compositions to prevent addiction |
| BR112012027794A2 (pt) | 2010-04-30 | 2016-08-02 | Takeda Pharmaceutical | tablete entérico |
| RS55777B1 (sr) | 2010-11-05 | 2017-07-31 | H Lundbeck As | Postupak za proizvodnju naltreksona |
| CN104955483A (zh) | 2013-01-30 | 2015-09-30 | 法莫斯医疗公司 | 用低剂量药剂治疗抑郁症和其它疾病 |
| JP6479766B2 (ja) | 2013-04-17 | 2019-03-06 | ハー・ルンドベック・アクチエゼルスカベット | 不安障害患者の治療のためのナルメフェン |
| JP6416213B2 (ja) * | 2013-04-17 | 2018-10-31 | ハー・ルンドベック・アクチエゼルスカベット | 気分障害患者の治療のためのナルメフェン |
-
2014
- 2014-12-18 JP JP2016540981A patent/JP6448645B2/ja active Active
- 2014-12-18 MX MX2016007947A patent/MX368870B/es active IP Right Grant
- 2014-12-18 RU RU2016123972A patent/RU2679661C1/ru not_active IP Right Cessation
- 2014-12-18 US US15/105,701 patent/US10376506B2/en active Active
- 2014-12-18 WO PCT/EP2014/078515 patent/WO2015091833A1/en not_active Ceased
- 2014-12-18 CA CA2933733A patent/CA2933733A1/en not_active Abandoned
- 2014-12-18 CN CN201480069586.5A patent/CN105828821B/zh active Active
- 2014-12-18 EP EP14818973.1A patent/EP3082815B1/en active Active
- 2014-12-18 KR KR1020167016182A patent/KR20160093025A/ko not_active Withdrawn
- 2014-12-18 SG SG11201604944PA patent/SG11201604944PA/en unknown
- 2014-12-18 AU AU2014368548A patent/AU2014368548B2/en not_active Ceased
- 2014-12-18 ES ES14818973.1T patent/ES2694352T3/es active Active
-
2016
- 2016-06-15 IL IL246253A patent/IL246253A0/en unknown
- 2016-06-17 CL CL2016001570A patent/CL2016001570A1/es unknown
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