IL212919A - Highly concentrated concentrates with low viscosity - Google Patents
Highly concentrated concentrates with low viscosityInfo
- Publication number
- IL212919A IL212919A IL212919A IL21291911A IL212919A IL 212919 A IL212919 A IL 212919A IL 212919 A IL212919 A IL 212919A IL 21291911 A IL21291911 A IL 21291911A IL 212919 A IL212919 A IL 212919A
- Authority
- IL
- Israel
- Prior art keywords
- low viscosity
- highly concentrated
- concentrated suspensions
- viscosity highly
- suspensions
- Prior art date
Links
- 239000000725 suspension Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
- A61K38/385—Serum albumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11508008P | 2008-11-16 | 2008-11-16 | |
| PCT/US2009/063852 WO2010056657A2 (en) | 2008-11-16 | 2009-11-10 | Low viscosity highly concentrated suspensions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL212919A0 IL212919A0 (en) | 2011-07-31 |
| IL212919A true IL212919A (en) | 2017-07-31 |
Family
ID=42170660
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL212919A IL212919A (en) | 2008-11-16 | 2011-05-16 | Highly concentrated concentrates with low viscosity |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US8779094B2 (enExample) |
| EP (1) | EP2376522A4 (enExample) |
| JP (2) | JP5711138B2 (enExample) |
| KR (1) | KR20110103961A (enExample) |
| CA (1) | CA2743789C (enExample) |
| IL (1) | IL212919A (enExample) |
| WO (1) | WO2010056657A2 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2170283T3 (en) | 2007-06-22 | 2019-04-15 | Univ Texas | CREATION OF STABLE SUBMICRON Peptide OR PROTEIN PARTICLES BY THIN FILM FREEZING |
| US9072668B2 (en) | 2010-03-09 | 2015-07-07 | Janssen Biotech, Inc. | Non-aqueous high concentration reduced viscosity suspension formulations of antibodies |
| US20110223208A1 (en) * | 2010-03-09 | 2011-09-15 | Beth Hill | Non-Aqueous High Concentration Reduced Viscosity Suspension Formulations |
| CA2792517C (en) * | 2010-03-09 | 2020-03-24 | Janssen Biotech, Inc. | Non-aqueous high concentration reduced viscosity suspension formulations |
| US9445990B2 (en) * | 2010-10-06 | 2016-09-20 | Medtronic, Inc. | TNF inhibitor formulation for use in implantable infusion devices |
| AU2012225277A1 (en) * | 2011-03-10 | 2013-09-26 | Board Of Regents, The University Of Texas System | Protein nanoparticle dispersions |
| CA2951856A1 (en) | 2011-10-28 | 2013-05-02 | Integritybio Inc. | Protein formulations containing amino acids |
| WO2013070692A1 (en) | 2011-11-07 | 2013-05-16 | Battelle Memorial Institute | Processes for delivery of viscous drug therapies |
| MY188825A (en) * | 2012-05-18 | 2022-01-06 | Genentech Inc | High-concentration monoclonal antibody formulations |
| HK1220120A1 (zh) * | 2013-03-15 | 2017-04-28 | Ansun Biopharma, Inc. | 制造注射蛋白质微粒悬浮液的方法 |
| IL312865B2 (en) | 2013-09-11 | 2025-06-01 | Eagle Biologics Inc | Liquid protein formulations containing viscosity-lowering agents |
| CN103976947B (zh) * | 2014-06-05 | 2016-08-17 | 段明星 | 一种含酶油悬浮剂及其制备方法与应用 |
| AU2015325055B2 (en) | 2014-10-01 | 2021-02-25 | Eagle Biologics, Inc. | Polysaccharide and nucleic acid formulations containing viscosity-lowering agents |
| JP5774190B1 (ja) * | 2014-12-12 | 2015-09-09 | ジーンメディカル株式会社 | 皮下注射用剤及び皮下注射用剤を含有する注射器の製造方法 |
| EP3231433B1 (en) * | 2014-12-12 | 2023-12-27 | Motejo. Ltd | Agent for hypodermic injection |
| MA46466A (fr) * | 2016-10-06 | 2019-08-14 | Amgen Inc | Formulations pharmaceutiques de protéines à viscosité réduite |
| AU2017364077A1 (en) | 2016-11-22 | 2019-06-20 | Elektrofi, Inc. | Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof |
| AU2018306303A1 (en) | 2017-07-25 | 2020-02-20 | Elektrofi, Inc. | Formation of particles including agents |
| US12115262B2 (en) | 2018-05-24 | 2024-10-15 | Elektrofi, Inc. | Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof |
| KR102051808B1 (ko) | 2018-07-23 | 2019-12-04 | 주식회사 종근당 | 테스토스테론 운데카노에이트를 포함하는 안정한 약제학적 조성물 |
| AU2020214626B2 (en) | 2019-01-31 | 2025-10-16 | Elektrofi, Inc. | Particle formation and morphology |
| KR20210125032A (ko) | 2019-02-05 | 2021-10-15 | 린디 바이오사이언시스, 아이엔씨. | 세포 배양 성분 및 액체 세포 배양 배지로부터 이를 단리하는 방법 |
| US20200376128A1 (en) * | 2019-06-01 | 2020-12-03 | Lupin Holdings B.V. | Monodisperse resorbable polyester polymer compositions, systems, and methods |
| JP7781743B2 (ja) * | 2019-09-13 | 2025-12-08 | エレクトロフィ,インコーポレイテッド | 疾患の処置のための治療用生物学的作用剤の送達のための組成物及び方法 |
| JP2023522627A (ja) | 2020-04-17 | 2023-05-31 | エレクトロフィ,インコーポレイテッド | 連続的な液滴形成及び脱水によって粒子を形成する方法 |
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| BE795516A (fr) | 1972-02-17 | 1973-08-16 | Ciba Geigy | Preparations de peptides huileuses et injectables et procede pour leur preparation |
| US4310516A (en) | 1980-02-01 | 1982-01-12 | Block Drug Company Inc. | Cosmetic and pharmaceutical vehicle thickened with solid emulsifier |
| EP0079143A3 (en) | 1981-10-20 | 1984-11-21 | Adnovum Ag | Pseudoplastic gel transfer |
| US4594108A (en) | 1983-09-19 | 1986-06-10 | The Dow Chemical Company | Highly pseudoplastic polymer solutions |
| US5411951A (en) | 1984-10-04 | 1995-05-02 | Monsanto Company | Prolonged release of biologically active somatotropin |
| US5288479A (en) | 1989-01-17 | 1994-02-22 | Sterling Drug, Inc. | Extrudable elastic oral pharmaceutical gel compositions and metered dose dispensers containing them and method of making and method of use thereof |
| SE465950B (sv) | 1989-10-23 | 1991-11-25 | Medinvent Sa | Kombination av ett aggregat partikelformat, kristallint eller frystorkat laekemedel med en pseudoplastisk gel foer beredning av ett injicerbart preparat samt foerfarande foer dess framstaellning |
| US5300302A (en) | 1990-10-04 | 1994-04-05 | Nestec S.A. | Pharmaceutical composition in gel form in a dispensing package |
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| WO1993020134A1 (en) | 1992-03-30 | 1993-10-14 | Alza Corporation | Additives for bioerodible polymers to regulate degradation |
| MX9301823A (es) | 1992-03-30 | 1994-01-31 | Alza Corp | Composicion para el suministro de liberacion controlado de un agente biologicamente activo. |
| US5512293A (en) | 1992-07-23 | 1996-04-30 | Alza Corporation | Oral sustained release drug delivery device |
| SE9203594D0 (sv) | 1992-11-30 | 1992-11-30 | Christer Nystroem | Laekemedel i dispersa system |
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| US5904935A (en) | 1995-06-07 | 1999-05-18 | Alza Corporation | Peptide/protein suspending formulations |
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| US5916582A (en) | 1996-07-03 | 1999-06-29 | Alza Corporation | Aqueous formulations of peptides |
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| US7258869B1 (en) | 1999-02-08 | 2007-08-21 | Alza Corporation | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle |
| FR2809309B1 (fr) * | 2000-05-23 | 2004-06-11 | Mainelab | Microspheres a liberation prolongee pour administration injectable |
| WO2002043580A2 (en) | 2000-10-27 | 2002-06-06 | Epic Therapeutics, Inc. | Production of microspheres |
| US20040022861A1 (en) | 2001-01-30 | 2004-02-05 | Williams Robert O. | Process for production of nanoparticles and microparticles by spray freezing into liquid |
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| US20070015689A1 (en) | 2005-06-23 | 2007-01-18 | Alza Corporation | Complexation of metal ions with polypeptides |
| EP1968550A2 (en) | 2005-12-16 | 2008-09-17 | University Of Kansas | Nanoclusters for delivery of therapeutics |
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| DK2170283T3 (en) | 2007-06-22 | 2019-04-15 | Univ Texas | CREATION OF STABLE SUBMICRON Peptide OR PROTEIN PARTICLES BY THIN FILM FREEZING |
| CN101081882A (zh) * | 2007-07-06 | 2007-12-05 | 天津大学 | 大分子印迹交联聚乙烯基吡咯烷酮微球及低温悬浮聚合制备方法 |
| JP2009173610A (ja) | 2008-01-28 | 2009-08-06 | Fujifilm Corp | タンパク質ナノ粒子 |
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| AU2009244742B2 (en) | 2008-05-09 | 2014-11-06 | South Dakota State University | Method of forming non-immunogenic hydrophobic protein nanoparticles and uses therefor |
| US20100009007A1 (en) | 2008-07-10 | 2010-01-14 | Baxter International Inc. | Non-covalent modification of microparticles and process of preparing same |
| US8323685B2 (en) | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing compositions containing microparticles |
| WO2010100200A2 (en) | 2009-03-05 | 2010-09-10 | Novartis Ag | Lyophilised antibody formulation |
-
2009
- 2009-11-10 JP JP2011536414A patent/JP5711138B2/ja not_active Expired - Fee Related
- 2009-11-10 WO PCT/US2009/063852 patent/WO2010056657A2/en not_active Ceased
- 2009-11-10 US US13/129,283 patent/US8779094B2/en active Active
- 2009-11-10 CA CA2743789A patent/CA2743789C/en active Active
- 2009-11-10 KR KR1020117013867A patent/KR20110103961A/ko not_active Withdrawn
- 2009-11-10 EP EP09826617.4A patent/EP2376522A4/en not_active Withdrawn
-
2011
- 2011-05-16 IL IL212919A patent/IL212919A/en active IP Right Grant
-
2014
- 2014-06-05 US US14/297,403 patent/US20140378370A1/en not_active Abandoned
- 2014-12-08 JP JP2014247793A patent/JP2015083582A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2376522A2 (en) | 2011-10-19 |
| WO2010056657A8 (en) | 2010-08-26 |
| CA2743789C (en) | 2017-10-31 |
| JP2012508744A (ja) | 2012-04-12 |
| CA2743789A1 (en) | 2010-05-20 |
| US20140378370A1 (en) | 2014-12-25 |
| US20110280864A1 (en) | 2011-11-17 |
| JP5711138B2 (ja) | 2015-04-30 |
| IL212919A0 (en) | 2011-07-31 |
| JP2015083582A (ja) | 2015-04-30 |
| EP2376522A4 (en) | 2013-12-25 |
| WO2010056657A3 (en) | 2010-10-14 |
| WO2010056657A2 (en) | 2010-05-20 |
| US8779094B2 (en) | 2014-07-15 |
| KR20110103961A (ko) | 2011-09-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |