JP2015083582A5 - - Google Patents
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- Publication number
- JP2015083582A5 JP2015083582A5 JP2014247793A JP2014247793A JP2015083582A5 JP 2015083582 A5 JP2015083582 A5 JP 2015083582A5 JP 2014247793 A JP2014247793 A JP 2014247793A JP 2014247793 A JP2014247793 A JP 2014247793A JP 2015083582 A5 JP2015083582 A5 JP 2015083582A5
- Authority
- JP
- Japan
- Prior art keywords
- suspension
- less
- volume
- suspension according
- gauge needle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000725 suspension Substances 0.000 claims 6
- 239000002245 particle Substances 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 238000007920 subcutaneous administration Methods 0.000 claims 1
Claims (6)
- タンパク質濃度が２００ｍｇ／ｍＬ以上であり、かつ粘度が５０センチポアズ未満である、対象への皮下送達に用いるためのタンパク質粒子の懸濁液。
- 送達が、２１〜２７ゲージの針を備える注射器を用いて達成される、請求項１に記載の懸濁液。
- 注射器が２５〜２７ゲージの針を備える、請求項２に記載の懸濁液。
- 体積が５ｍＬ以下である、請求項１〜３のいずれか１項に記載の懸濁液。
- 体積が１．５ｍＬ以下である、請求項１〜３のいずれか１項に記載の懸濁液。
- タンパク質粒子がサブミクロンサイズの粒子である、請求項１〜５のいずれか１項に記載の懸濁液。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11508008P | 2008-11-16 | 2008-11-16 | |
| US61/115,080 | 2008-11-16 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011536414A Division JP5711138B2 (ja) | 2008-11-16 | 2009-11-10 | 高濃度の低粘度懸濁液 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015083582A JP2015083582A (ja) | 2015-04-30 |
| JP2015083582A5 true JP2015083582A5 (ja) | 2015-07-02 |
Family
ID=42170660
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011536414A Expired - Fee Related JP5711138B2 (ja) | 2008-11-16 | 2009-11-10 | 高濃度の低粘度懸濁液 |
| JP2014247793A Pending JP2015083582A (ja) | 2008-11-16 | 2014-12-08 | 高濃度の低粘度懸濁液 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011536414A Expired - Fee Related JP5711138B2 (ja) | 2008-11-16 | 2009-11-10 | 高濃度の低粘度懸濁液 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US8779094B2 (ja) |
| EP (1) | EP2376522A4 (ja) |
| JP (2) | JP5711138B2 (ja) |
| KR (1) | KR20110103961A (ja) |
| CA (1) | CA2743789C (ja) |
| IL (1) | IL212919A (ja) |
| WO (1) | WO2010056657A2 (ja) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2170283T3 (en) | 2007-06-22 | 2019-04-15 | Univ Texas | CREATION OF STABLE SUBMICRON Peptide OR PROTEIN PARTICLES BY THIN FILM FREEZING |
| US20110223208A1 (en) * | 2010-03-09 | 2011-09-15 | Beth Hill | Non-Aqueous High Concentration Reduced Viscosity Suspension Formulations |
| US9072668B2 (en) | 2010-03-09 | 2015-07-07 | Janssen Biotech, Inc. | Non-aqueous high concentration reduced viscosity suspension formulations of antibodies |
| CA2792517C (en) * | 2010-03-09 | 2020-03-24 | Janssen Biotech, Inc. | Non-aqueous high concentration reduced viscosity suspension formulations |
| US9445990B2 (en) * | 2010-10-06 | 2016-09-20 | Medtronic, Inc. | TNF inhibitor formulation for use in implantable infusion devices |
| CA2829629A1 (en) * | 2011-03-10 | 2012-09-13 | Board Of Regents, The University Of Texas System | Protein nanoparticle dispersions |
| CA2951856A1 (en) | 2011-10-28 | 2013-05-02 | Integritybio Inc. | Protein formulations containing amino acids |
| US9737662B2 (en) | 2011-11-07 | 2017-08-22 | Battelle Memorial Institute | Processes for delivery of viscous drug therapies |
| CA2873646C (en) * | 2012-05-18 | 2022-04-26 | Genentech, Inc. | High-concentration monoclonal antibody formulations |
| WO2014151705A1 (en) * | 2013-03-15 | 2014-09-25 | Ansun Biopharma, Inc. | Methods for preparing injectable protein microparticle suspensions |
| KR20240042200A (ko) | 2013-09-11 | 2024-04-01 | 이글 바이오로직스 인코퍼레이티드 | 점도저하제를 함유하는 액체 단백질 제형 |
| CN103976947B (zh) * | 2014-06-05 | 2016-08-17 | 段明星 | 一种含酶油悬浮剂及其制备方法与应用 |
| KR102497368B1 (ko) * | 2014-10-01 | 2023-02-10 | 이글 바이올로직스 인코포레이티드 | 점도-저하제를 함유하는 폴리삭카라이드 및 핵산 제형 |
| US10918766B2 (en) | 2014-12-12 | 2021-02-16 | Motejo Ltd. | Agent for hypodermic injection |
| JP5774190B1 (ja) * | 2014-12-12 | 2015-09-09 | ジーンメディカル株式会社 | 皮下注射用剤及び皮下注射用剤を含有する注射器の製造方法 |
| WO2018067987A1 (en) * | 2016-10-06 | 2018-04-12 | Amgen Inc. | Reduced viscosity protein pharmaceutical formulations |
| KR102051808B1 (ko) | 2018-07-23 | 2019-12-04 | 주식회사 종근당 | 테스토스테론 운데카노에이트를 포함하는 안정한 약제학적 조성물 |
| WO2020160323A2 (en) | 2019-01-31 | 2020-08-06 | Elektrofi, Inc. | Particle formation and morphology |
| US20220119760A1 (en) | 2019-02-05 | 2022-04-21 | Lindy Biosciences, Inc. | Isolated cell culture components and methods for isolating the same from liquid cell culture medium |
| CN114514035A (zh) * | 2019-09-13 | 2022-05-17 | 伊勒卓菲公司 | 递送用于治疗疾病的治疗性生物制剂的组合物和方法 |
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| DK2170283T3 (en) | 2007-06-22 | 2019-04-15 | Univ Texas | CREATION OF STABLE SUBMICRON Peptide OR PROTEIN PARTICLES BY THIN FILM FREEZING |
| CN101081882A (zh) * | 2007-07-06 | 2007-12-05 | 天津大学 | 大分子印迹交联聚乙烯基吡咯烷酮微球及低温悬浮聚合制备方法 |
| JP2009173610A (ja) | 2008-01-28 | 2009-08-06 | Fujifilm Corp | タンパク質ナノ粒子 |
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| CA2723563C (en) | 2008-05-09 | 2017-12-12 | South Dakota State University | Method of forming non-immunogenic hydrophobic protein nanoparticles, and uses therefor |
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-
2009
- 2009-11-10 US US13/129,283 patent/US8779094B2/en active Active
- 2009-11-10 JP JP2011536414A patent/JP5711138B2/ja not_active Expired - Fee Related
- 2009-11-10 KR KR1020117013867A patent/KR20110103961A/ko not_active Application Discontinuation
- 2009-11-10 CA CA2743789A patent/CA2743789C/en active Active
- 2009-11-10 WO PCT/US2009/063852 patent/WO2010056657A2/en active Application Filing
- 2009-11-10 EP EP09826617.4A patent/EP2376522A4/en not_active Withdrawn
-
2011
- 2011-05-16 IL IL212919A patent/IL212919A/en active IP Right Grant
-
2014
- 2014-06-05 US US14/297,403 patent/US20140378370A1/en not_active Abandoned
- 2014-12-08 JP JP2014247793A patent/JP2015083582A/ja active Pending
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