JP2014534266A5 - - Google Patents

Download PDF

Info

Publication number
JP2014534266A5
JP2014534266A5 JP2014543634A JP2014543634A JP2014534266A5 JP 2014534266 A5 JP2014534266 A5 JP 2014534266A5 JP 2014543634 A JP2014543634 A JP 2014543634A JP 2014543634 A JP2014543634 A JP 2014543634A JP 2014534266 A5 JP2014534266 A5 JP 2014534266A5
Authority
JP
Japan
Prior art keywords
tsgl
polypeptide
molecule
seq
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2014543634A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014534266A (ja
JP6181066B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2012/066910 external-priority patent/WO2013082200A1/en
Publication of JP2014534266A publication Critical patent/JP2014534266A/ja
Publication of JP2014534266A5 publication Critical patent/JP2014534266A5/ja
Application granted granted Critical
Publication of JP6181066B2 publication Critical patent/JP6181066B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2014543634A 2011-11-28 2012-11-28 新規な増強型セレクチンアンタゴニスト Active JP6181066B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161564275P 2011-11-28 2011-11-28
US61/564,275 2011-11-28
PCT/US2012/066910 WO2013082200A1 (en) 2011-11-28 2012-11-28 Novel enhanced selectin antagonists

Publications (3)

Publication Number Publication Date
JP2014534266A JP2014534266A (ja) 2014-12-18
JP2014534266A5 true JP2014534266A5 (https=) 2015-12-24
JP6181066B2 JP6181066B2 (ja) 2017-08-16

Family

ID=48467086

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014543634A Active JP6181066B2 (ja) 2011-11-28 2012-11-28 新規な増強型セレクチンアンタゴニスト

Country Status (5)

Country Link
US (1) US8889628B2 (https=)
EP (1) EP2785843B1 (https=)
JP (1) JP6181066B2 (https=)
CA (1) CA2857019C (https=)
WO (1) WO2013082200A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10253071B2 (en) 2013-06-03 2019-04-09 Beth Israel Deaconess Medical Center, Inc. Selectin inhibitors, composition, and uses related thereto
EP3568159A4 (en) 2017-01-11 2020-08-05 Bristol-Myers Squibb Company PSGL-1 ANTAGONISTS AND THEIR USES
KR102715540B1 (ko) 2017-03-14 2024-10-08 파이브 프라임 테라퓨틱스, 인크. 산성 pH에서 VISTA에 결합하는 항체
US12479904B2 (en) 2017-12-29 2025-11-25 Gray D Shaw Methods of treating cytokine release syndrome by administering a molecule comprising a soluble tandem selectin glycoprotein ligand
BR112020019083A2 (pt) 2018-03-21 2020-12-29 Five Prime Therapeutics, Inc. Anticorpos, ácido nucleico, composições, célula e métodos para preparar um anticorpo, para tratar câncer, para tratar uma doença infecciosa, para tratar uma inflamação, para a identificação de um anticorpo, para melhorar a eficácia antitumoral de um anticorpo, para melhorar a farmacocinética de um anticorpo, para selecionar um anticorpo, para melhorar a eficácia de anticorpos, para isolar anticorpos, para detectar vista em uma amostra e para tratar câncer
BR112021000303A2 (pt) 2018-07-11 2021-04-13 Five Prime Therapeutics, Inc. Anticorpos que se ligam a vista em ph ácido
WO2021183685A2 (en) * 2020-03-10 2021-09-16 Shaw Gray D Fusion molecules of psgl-1 or tsgl anionic domains to checkpoint-modulating antibodies and other antibodies
EP4404971A1 (en) * 2021-09-23 2024-07-31 Beth Israel Deaconess Medical Center, Inc. P-selectin inhibitors and uses thereof
WO2026080432A1 (en) * 2024-10-07 2026-04-16 Beth Israel Deaconess Medical Center, Inc. Dimeric p-selectin inhibitors and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6277975B1 (en) 1992-10-23 2001-08-21 Genetics Institute, Inc. Fusions of P-selectin ligand protein and polynucleotides encoding same
JP2002542785A (ja) * 1999-04-23 2002-12-17 セプティア, インコーポレイテッド Dsp−10二重特異性mapキナーゼホスファターゼ
WO2001075107A2 (en) * 2000-03-31 2001-10-11 Genetics Institute, Llc. Use of p-selectin glycoprotein ligand-1 (psgl-1) and fragments thereof for the inhibition of thrombosis
US20040086519A1 (en) * 2000-09-12 2004-05-06 Genetics Institute, Llc Inhibition of stenosis or restenosis by P-selectin ligand antagonists
CA2457400A1 (en) * 2001-08-03 2003-02-20 Genetics Institute, Llc Modulation of leukocyte-endothelial interactions following ischemia
JP2009510102A (ja) * 2005-09-29 2009-03-12 ヴァイラル ロジック システムズ テクノロジー コーポレーション 免疫調節組成物およびその使用
CA2748314C (en) * 2009-02-03 2018-10-02 Amunix Operating Inc. Extended recombinant polypeptides and compositions comprising same

Similar Documents

Publication Publication Date Title
JP2014534266A5 (https=)
JP2016000731A5 (https=)
JP2012522529A5 (https=)
PE20221909A1 (es) Moleculas de union a antigeno que comprenden un trimero de ligando de la familia de tnf
JP2015512893A5 (https=)
JP2012082206A5 (https=)
JP2012025737A5 (https=)
JP2015525217A5 (https=)
JP2010088434A5 (https=)
JP2015212284A5 (https=)
RU2021124437A (ru) Конструкции, направленные на комплексы пептида afp/mhc, и виды их использования
RU2011138844A (ru) Композиции бендамустина и циклополисахарида
JP2017529067A5 (https=)
JP2017184723A5 (https=)
HRP20250195T1 (hr) Anti-fcrn antitijela
JP2014525735A5 (https=)
NZ628446A (en) Fibronectin based scaffold domain proteins that bind to myostatin
EA201270802A1 (ru) Димерные слитые белки vstm3 и связанные с ними композиции и способы
JP2018522563A5 (https=)
JP2017512063A5 (https=)
JP2013509879A5 (https=)
NZ703585A (en) Blood brain barrier shuttle
WO2008114149A3 (en) Respiratory syncytial virus (rsv) chimeric polypeptide comprising the g protein central region domain located in between the f2 and f1 fusion protein domains
FI2968461T3 (fi) Fuusioproteiineja, jotka käsittävät pdgf:ää ja vegf:ää sitovia osia, ja menetelmiä niiden käyttämiseksi
AR066311A1 (es) Moleculas de anticuerpos anti proteina hsp90 fungica y acidos nucleicos que los codifican