AR066311A1 - Moleculas de anticuerpos anti proteina hsp90 fungica y acidos nucleicos que los codifican - Google Patents
Moleculas de anticuerpos anti proteina hsp90 fungica y acidos nucleicos que los codificanInfo
- Publication number
- AR066311A1 AR066311A1 ARP080101768A ARP080101768A AR066311A1 AR 066311 A1 AR066311 A1 AR 066311A1 AR P080101768 A ARP080101768 A AR P080101768A AR P080101768 A ARP080101768 A AR P080101768A AR 066311 A1 AR066311 A1 AR 066311A1
- Authority
- AR
- Argentina
- Prior art keywords
- fungica
- hsp90
- nucleic acids
- protein antibodies
- acids coding
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/14—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from fungi, algea or lichens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Rheumatology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Péptido scFv, el cual comprende un dominio VH y un dominio VL enlazados por un espaciador de aminoácidos. El dominio VH comprende una secuencia con una identidad de secuencia de cuando menos el 80% con la secuencia de la SEQ ID N°:64. El dominio VL comprende una secuencia con una identidad de secuencia de cuando menos el 80% con la secuencia de la SEQ ID N°:66. El péptido scFv también comprende la sustitucion o la supresion de un aminoácido en el dominio VH en la posicion correspondiente a C28. También composiciones farmacéuticas que comprenden tales péptidos así como el uso de las mismas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07107140 | 2007-04-27 | ||
| EP07113353 | 2007-07-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR066311A1 true AR066311A1 (es) | 2009-08-12 |
Family
ID=39717534
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080101768A AR066311A1 (es) | 2007-04-27 | 2008-04-25 | Moleculas de anticuerpos anti proteina hsp90 fungica y acidos nucleicos que los codifican |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US20100113355A1 (es) |
| EP (2) | EP2144932A1 (es) |
| JP (1) | JP2010524485A (es) |
| KR (1) | KR20100017387A (es) |
| CN (1) | CN101679517A (es) |
| AR (1) | AR066311A1 (es) |
| AU (1) | AU2008244308A1 (es) |
| BR (1) | BRPI0810827A2 (es) |
| CA (1) | CA2685136A1 (es) |
| CL (1) | CL2008001202A1 (es) |
| CR (1) | CR11059A (es) |
| EA (1) | EA200901441A1 (es) |
| EC (1) | ECSP099765A (es) |
| GT (1) | GT200900276A (es) |
| IL (1) | IL201445A0 (es) |
| MA (1) | MA31384B1 (es) |
| MX (1) | MX2009011595A (es) |
| PE (1) | PE20090728A1 (es) |
| TN (1) | TN2009000442A1 (es) |
| TW (1) | TW200902714A (es) |
| WO (2) | WO2008132134A1 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100113355A1 (en) | 2007-04-27 | 2010-05-06 | Naresh Chennamsetty | Novel antibody molecules and nucleic acids binding to fungal stress protein hsp90 |
| CA2956161A1 (en) * | 2014-07-23 | 2016-01-28 | Ohio State Innovation Foundation | Methods and compositions related to antibody fragments that bind to tumor-associated glycoprotein 72 (tag-72) |
| CN105652011B (zh) * | 2014-11-20 | 2017-09-22 | 深圳市安群生物工程有限公司 | 检测人HSP90α‑2蛋白的荧光免疫层析试纸及其制备方法 |
| CN113845591B (zh) * | 2018-10-30 | 2023-10-31 | 迈威(上海)生物科技股份有限公司 | Hsp90抗体及其在抗真菌感染中的应用 |
| WO2024040194A1 (en) | 2022-08-17 | 2024-02-22 | Capstan Therapeutics, Inc. | Conditioning for in vivo immune cell engineering |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4732852A (en) * | 1981-11-20 | 1988-03-22 | Cetus Corporation | Site directed peptidase cleavage |
| US4670382A (en) | 1983-12-02 | 1987-06-02 | Temple University--of the Commonwealth System of Higher Education | Monoclonal antibody to Candida albicans cytoplasmic antigens and methods of preparing same |
| US4806465A (en) * | 1984-01-16 | 1989-02-21 | Temple University Of The Commonwealth System Of Higher Education | Cytoplasmic antigens of candida albicans and methods of using the same |
| GB8506373D0 (en) | 1985-03-12 | 1985-04-11 | Axon Healthcare Ltd | Antigens antibodies |
| GB8915019D0 (en) * | 1989-06-30 | 1989-08-23 | Matthews Ruth C | Medicaments |
| EP0861893A3 (en) | 1991-09-19 | 1999-11-10 | Genentech, Inc. | High level expression of immunoglobulin polypeptides |
| GB2270076A (en) | 1992-08-18 | 1994-03-02 | Univ Manchester | Human HSP 90 Epitopes |
| CA2370007A1 (en) | 1999-04-09 | 2000-10-19 | Sloan-Kettering Institute For Cancer Research | Methods and compositions for degradation and/or inhibition of her-family tyrosine kinases |
| WO2001055174A2 (en) | 2000-01-25 | 2001-08-02 | Oklahoma Medical Research Foundation | Universal procedure for refolding recombinant proteins |
| GB0008305D0 (en) * | 2000-04-06 | 2000-05-24 | Neutec Pharma Plc | Treatment of fungal infections |
| WO2002006990A1 (en) | 2000-07-14 | 2002-01-24 | Healthcite, Inc. | Method and system for providing medical information |
| WO2002069900A2 (en) | 2001-03-01 | 2002-09-12 | Conforma Therapeutics Corp. | Methods for treating genetically-defined proliferative disorders with hsp90 inhibitors |
| GB0127983D0 (en) | 2001-11-22 | 2002-01-16 | Neutec Pharma Plc | Treatment of micro-organism infection |
| GB0315111D0 (en) | 2003-06-27 | 2003-07-30 | Cancer Rec Tech Ltd | Substituted 5-membered ring compounds and their use |
| GB0409077D0 (en) | 2004-04-23 | 2004-05-26 | Neutec Pharma Plc | Treatment of fungal infections |
| RU2389507C2 (ru) * | 2004-07-02 | 2010-05-20 | Ньютек Фарма Плс | Лечение рака |
| US20100113355A1 (en) | 2007-04-27 | 2010-05-06 | Naresh Chennamsetty | Novel antibody molecules and nucleic acids binding to fungal stress protein hsp90 |
| WO2008132174A1 (en) | 2007-04-27 | 2008-11-06 | Novartis Ag | An immunoglobulin composition |
-
2006
- 2006-04-24 US US12/597,229 patent/US20100113355A1/en not_active Abandoned
-
2008
- 2008-04-24 MX MX2009011595A patent/MX2009011595A/es unknown
- 2008-04-24 WO PCT/EP2008/055006 patent/WO2008132134A1/en active Application Filing
- 2008-04-24 JP JP2010504689A patent/JP2010524485A/ja active Pending
- 2008-04-24 CN CN200880013913A patent/CN101679517A/zh active Pending
- 2008-04-24 EA EA200901441A patent/EA200901441A1/ru unknown
- 2008-04-24 EP EP08736541A patent/EP2144932A1/en not_active Withdrawn
- 2008-04-24 US US12/150,076 patent/US7722869B2/en not_active Expired - Fee Related
- 2008-04-24 EP EP08749716A patent/EP2152746A1/en not_active Withdrawn
- 2008-04-24 BR BRPI0810827-7A2A patent/BRPI0810827A2/pt not_active Application Discontinuation
- 2008-04-24 AU AU2008244308A patent/AU2008244308A1/en not_active Abandoned
- 2008-04-24 CA CA002685136A patent/CA2685136A1/en not_active Abandoned
- 2008-04-24 KR KR1020097024646A patent/KR20100017387A/ko not_active Application Discontinuation
- 2008-04-24 WO PCT/EP2008/055037 patent/WO2008132152A1/en active Application Filing
- 2008-04-25 AR ARP080101768A patent/AR066311A1/es unknown
- 2008-04-25 TW TW097115380A patent/TW200902714A/zh unknown
- 2008-04-25 CL CL2008001202A patent/CL2008001202A1/es unknown
- 2008-04-25 PE PE2008000709A patent/PE20090728A1/es not_active Application Discontinuation
-
2009
- 2009-10-09 CR CR11059A patent/CR11059A/es not_active Application Discontinuation
- 2009-10-11 IL IL201445A patent/IL201445A0/en unknown
- 2009-10-23 GT GT200900276A patent/GT200900276A/es unknown
- 2009-10-23 TN TNP2009000442A patent/TN2009000442A1/fr unknown
- 2009-11-20 MA MA32355A patent/MA31384B1/fr unknown
- 2009-11-27 EC EC2009009765A patent/ECSP099765A/es unknown
-
2010
- 2010-03-08 US US12/719,049 patent/US20100166758A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008132134A1 (en) | 2008-11-06 |
| CA2685136A1 (en) | 2008-11-06 |
| CR11059A (es) | 2009-11-20 |
| MA31384B1 (fr) | 2010-05-03 |
| US20100166758A1 (en) | 2010-07-01 |
| WO2008132152A1 (en) | 2008-11-06 |
| US7722869B2 (en) | 2010-05-25 |
| CN101679517A (zh) | 2010-03-24 |
| EP2144932A1 (en) | 2010-01-20 |
| WO2008132134A9 (en) | 2009-07-09 |
| TW200902714A (en) | 2009-01-16 |
| EA200901441A1 (ru) | 2010-04-30 |
| US20090136484A1 (en) | 2009-05-28 |
| IL201445A0 (en) | 2010-06-16 |
| GT200900276A (es) | 2010-05-21 |
| JP2010524485A (ja) | 2010-07-22 |
| PE20090728A1 (es) | 2009-07-02 |
| TN2009000442A1 (en) | 2011-03-31 |
| US20100113355A1 (en) | 2010-05-06 |
| BRPI0810827A2 (pt) | 2014-10-29 |
| CL2008001202A1 (es) | 2008-12-19 |
| ECSP099765A (es) | 2009-12-28 |
| AU2008244308A1 (en) | 2008-11-06 |
| MX2009011595A (es) | 2009-12-08 |
| EP2152746A1 (en) | 2010-02-17 |
| KR20100017387A (ko) | 2010-02-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |