JP2014534261A5 - - Google Patents
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- Publication number
- JP2014534261A5 JP2014534261A5 JP2014543546A JP2014543546A JP2014534261A5 JP 2014534261 A5 JP2014534261 A5 JP 2014534261A5 JP 2014543546 A JP2014543546 A JP 2014543546A JP 2014543546 A JP2014543546 A JP 2014543546A JP 2014534261 A5 JP2014534261 A5 JP 2014534261A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- independently
- aryl
- heteroaryl
- ring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- WQZPUWMOQOEQHK-UHFFFAOYSA-N CON(C(CC1S(O)(=O)=O)=O)C1=O Chemical compound CON(C(CC1S(O)(=O)=O)=O)C1=O WQZPUWMOQOEQHK-UHFFFAOYSA-N 0.000 description 2
- JDFXJJLFADUZIY-UHFFFAOYSA-N CON(C(CC1)=O)C1=O Chemical compound CON(C(CC1)=O)C1=O JDFXJJLFADUZIY-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161562021P | 2011-11-21 | 2011-11-21 | |
| US61/562,021 | 2011-11-21 | ||
| PCT/US2012/066139 WO2013078244A1 (en) | 2011-11-21 | 2012-11-20 | Carboxy x rhodamine analogs |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017183422A Division JP6574821B2 (ja) | 2011-11-21 | 2017-09-25 | カルボキシｘローダミン類似体 |
| JP2018213096A Division JP7227741B2 (ja) | 2011-11-21 | 2018-11-13 | カルボキシｘローダミン類似体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014534261A JP2014534261A (ja) | 2014-12-18 |
| JP2014534261A5 true JP2014534261A5 (enExample) | 2017-11-16 |
| JP6522339B2 JP6522339B2 (ja) | 2019-05-29 |
Family
ID=47324436
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014543546A Active JP6522339B2 (ja) | 2011-11-21 | 2012-11-20 | カルボキシｘローダミン類似体 |
| JP2017183422A Active JP6574821B2 (ja) | 2011-11-21 | 2017-09-25 | カルボキシｘローダミン類似体 |
| JP2018213096A Active JP7227741B2 (ja) | 2011-11-21 | 2018-11-13 | カルボキシｘローダミン類似体 |
| JP2020209163A Pending JP2021063089A (ja) | 2011-11-21 | 2020-12-17 | カルボキシｘローダミン類似体 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017183422A Active JP6574821B2 (ja) | 2011-11-21 | 2017-09-25 | カルボキシｘローダミン類似体 |
| JP2018213096A Active JP7227741B2 (ja) | 2011-11-21 | 2018-11-13 | カルボキシｘローダミン類似体 |
| JP2020209163A Pending JP2021063089A (ja) | 2011-11-21 | 2020-12-17 | カルボキシｘローダミン類似体 |
Country Status (4)
| Country | Link |
|---|---|
| US (3) | US9056885B2 (enExample) |
| EP (1) | EP2782916B1 (enExample) |
| JP (4) | JP6522339B2 (enExample) |
| WO (1) | WO2013078244A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2269064B1 (en) | 2008-03-27 | 2016-11-30 | Promega Corporation | Protein labeling with cyanobenzothiazole conjugates |
| EP2782916B1 (en) * | 2011-11-21 | 2018-02-28 | Promega Corporation | Carboxy x rhodamine analogs |
| JP2015530114A (ja) * | 2012-09-26 | 2015-10-15 | プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ | リアルタイムモニタリング |
| US10067149B2 (en) | 2012-12-12 | 2018-09-04 | Promega Corporation | Recognition of cellular target binding by a bioactive agent using intracellular bioluminescence resonance energy transfer |
| BR112015013710B1 (pt) * | 2012-12-12 | 2022-08-09 | Promega Corporation | Métodos in vitro para detectar uma interação entre um agente bioativo e um alvo celular |
| US11072811B2 (en) | 2013-03-15 | 2021-07-27 | Promega Corporation | Substrates for covalent tethering of proteins to functional groups or solid surfaces |
| WO2014145458A1 (en) | 2013-03-15 | 2014-09-18 | Arizona Board Of Regents On Behalf Of Arizona State University | Nucleic acid-tagged compositions and methods for multiplexed protein-protein interaction profiling |
| JP6367307B2 (ja) | 2013-03-15 | 2018-08-01 | プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ | 遺伝的同一性における使用のための新規ケイ素およびゲルマニウム色素 |
| WO2015175873A1 (en) * | 2014-05-16 | 2015-11-19 | Life Technologies Corporation | Cell tracking reagents and their methods of use |
| WO2017059308A1 (en) | 2015-10-02 | 2017-04-06 | Promega Corporation | Methods for synthesizing rhodamine dyes |
| EP4144738A1 (en) * | 2016-11-01 | 2023-03-08 | Promega Corporation | Coelenterazine analogues tethered to energy acceptors |
| DK3548492T5 (en) | 2016-12-01 | 2024-08-05 | Promega Corp | Cell impermeable coelenterazine analogues |
| EP3578549A4 (en) * | 2017-02-03 | 2021-01-13 | Tohoku University | Heterocyclic compound |
| JP7419260B2 (ja) | 2018-05-01 | 2024-01-22 | プロメガ コーポレイション | ＮａｎｏＬｕｃ自殺基質としてのセレンテラジン化合物 |
| EP3803401A4 (en) | 2018-05-30 | 2022-02-23 | Promega Corporation | BROAD SPECTRUM KINASE BINDERS |
| US11175228B2 (en) | 2018-11-28 | 2021-11-16 | Promega Corporation | Reactive peptide labeling |
| BR112021012154A2 (pt) * | 2018-12-20 | 2021-09-08 | Life Technologies Corporation | Corante de rodamina assimétrica e uso da mesma em ensaios biológicos |
| WO2020191339A1 (en) | 2019-03-20 | 2020-09-24 | Promega Corporation | Photoaffinity probes |
| US12241839B2 (en) | 2019-11-27 | 2025-03-04 | Promega Corporation | Multipartite luciferase peptides and polypeptides |
| JP7745550B2 (ja) | 2019-12-10 | 2025-09-29 | プロメガ コーポレイション | 多官能性プローブを使用する生物発光検出用組成物及び生物発光検出方法 |
| WO2022047186A1 (en) | 2020-08-28 | 2022-03-03 | Promega Corporation | Target engagement assay for ras proteins |
| US20220195518A1 (en) * | 2020-12-22 | 2022-06-23 | Illumina Cambridge Limited | Methods and compositions for nucleic acid sequencing |
| WO2024263837A2 (en) * | 2023-06-22 | 2024-12-26 | Promega Corporation | Compounds and methods of use thereof for assessing target engagement for dna polymerase theta |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE591293A (fr) * | 1959-05-28 | 1960-11-28 | Geigy Ag J R | Nouveaux dérivés de l'iminodibenzyle et leur préparation. |
| US5171534A (en) | 1984-01-16 | 1992-12-15 | California Institute Of Technology | Automated DNA sequencing technique |
| CA1340806C (en) | 1986-07-02 | 1999-11-02 | James Merrill Prober | Method, system and reagents for dna sequencing |
| US4900686A (en) * | 1987-04-02 | 1990-02-13 | Polaroid Corporation | Fluorescent conjugates and biological diagnostic assay |
| US4965349A (en) * | 1987-12-24 | 1990-10-23 | Applied Biosystems, Inc. | Method of synthesizing oligonucleotides labeled with ammonia-labile groups on solid phase supports |
| US4997928A (en) | 1988-09-15 | 1991-03-05 | E. I. Du Pont De Nemours And Company | Fluorescent reagents for the preparation of 5'-tagged oligonucleotides |
| US5304644A (en) * | 1992-04-15 | 1994-04-19 | G. D. Searle & Co. | 1-,2-,3-,4-,5-,6-,7-,8- and/or 9 substituted dibenzoxazepine compounds, pharmaceutical compositions and methods for treating pain |
| DE69324494T2 (de) | 1992-09-03 | 1999-09-23 | The Perkin-Elmer Corp., Foster City | 4,7-dichlorofluoroszein-farbestoffe als molekulare sonden |
| US5658751A (en) | 1993-04-13 | 1997-08-19 | Molecular Probes, Inc. | Substituted unsymmetrical cyanine dyes with selected permeability |
| US6080852A (en) | 1996-06-27 | 2000-06-27 | The Perkin-Elmer Corporation | 4,7-dichlororhodamine dyes |
| US5936087A (en) * | 1997-11-25 | 1999-08-10 | The Perkin-Elmer Corporation | Dibenzorhodamine dyes |
| US6583168B1 (en) | 1997-11-25 | 2003-06-24 | Applera Corporation | Sulfonated diarylrhodamine dyes |
| EP1028113A4 (en) * | 1998-08-04 | 2004-10-13 | Toray Industries | HETEROCYCLIC DERIVATIVES OF BENZENE IN FUSION AND THEIR USE |
| US6403860B1 (en) | 1999-03-25 | 2002-06-11 | Pioneer Hi-Bred International, Inc. | Ku80 homologue and uses thereof |
| US6248884B1 (en) * | 1999-06-03 | 2001-06-19 | The Perkin-Elmer Corporation | Extended rhodamine compounds useful as fluorescent labels |
| WO2003034987A2 (en) * | 2001-10-19 | 2003-05-01 | Merck & Co., Inc. | Androgen receptor modulators and methods of use thereof |
| TW200305423A (en) | 2002-02-14 | 2003-11-01 | Ono Pharmaceutical Co | N-carbamoyl nitrogen-containing condensed ring compound and medicament containing same as active ingredient |
| EP2455457B1 (en) | 2003-01-31 | 2015-03-11 | Promega Corporation | Covalent tethering of functional groups to proteins |
| JP2007509608A (ja) | 2003-05-23 | 2007-04-19 | ウペエフエル・エコル・ポリテクニック・フェデラル・ドゥ・ローザンヌ | アシル担体タンパク質に基づくタンパク質をラベルするための方法 |
| JP2007534308A (ja) | 2003-11-19 | 2007-11-29 | アレロジック・バイオサイエンシズ・コーポレーション | 複数のフルオロフォアで標識したオリゴヌクレオチド |
| EP1882688A1 (en) | 2006-07-25 | 2008-01-30 | EPFL Ecole Polytechnique Fédérale de Lausanne | Labelling of fusion proteins with synthetic probes |
| CN101184082B (zh) | 2006-11-17 | 2011-04-20 | 华为技术有限公司 | 群组用户注册方法、状态更新方法、处理装置、ims网络实体和通信系统 |
| EP2269064B1 (en) | 2008-03-27 | 2016-11-30 | Promega Corporation | Protein labeling with cyanobenzothiazole conjugates |
| WO2009157196A1 (ja) * | 2008-06-25 | 2009-12-30 | 武田薬品工業株式会社 | アミド化合物 |
| WO2010127368A1 (en) | 2009-05-01 | 2010-11-04 | Promega Corporation | Synthetic oplophorus luciferases with enhanced light output |
| SG10202103336SA (en) | 2010-11-02 | 2021-04-29 | Promega Corp | Novel coelenterazine substrates and methods of use |
| EP2782916B1 (en) * | 2011-11-21 | 2018-02-28 | Promega Corporation | Carboxy x rhodamine analogs |
| BR112015013715A2 (pt) * | 2012-12-12 | 2017-09-26 | Promega Corp | sistema, método para capturar o alvo celular, lisado celular e ligante de captura. |
-
2012
- 2012-11-20 EP EP12798535.6A patent/EP2782916B1/en active Active
- 2012-11-20 US US13/682,589 patent/US9056885B2/en active Active
- 2012-11-20 JP JP2014543546A patent/JP6522339B2/ja active Active
- 2012-11-20 WO PCT/US2012/066139 patent/WO2013078244A1/en not_active Ceased
-
2015
- 2015-05-28 US US14/724,111 patent/US10139400B2/en active Active
-
2016
- 2016-07-07 US US15/204,664 patent/US10215751B2/en active Active
-
2017
- 2017-09-25 JP JP2017183422A patent/JP6574821B2/ja active Active
-
2018
- 2018-11-13 JP JP2018213096A patent/JP7227741B2/ja active Active
-
2020
- 2020-12-17 JP JP2020209163A patent/JP2021063089A/ja active Pending
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