JP2014534261A5 - - Google Patents
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- Publication number
- JP2014534261A5 JP2014534261A5 JP2014543546A JP2014543546A JP2014534261A5 JP 2014534261 A5 JP2014534261 A5 JP 2014534261A5 JP 2014543546 A JP2014543546 A JP 2014543546A JP 2014543546 A JP2014543546 A JP 2014543546A JP 2014534261 A5 JP2014534261 A5 JP 2014534261A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- independently
- aryl
- heteroaryl
- ring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- WQZPUWMOQOEQHK-UHFFFAOYSA-N CON(C(CC1S(O)(=O)=O)=O)C1=O Chemical compound CON(C(CC1S(O)(=O)=O)=O)C1=O WQZPUWMOQOEQHK-UHFFFAOYSA-N 0.000 description 2
- JDFXJJLFADUZIY-UHFFFAOYSA-N CON(C(CC1)=O)C1=O Chemical compound CON(C(CC1)=O)C1=O JDFXJJLFADUZIY-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161562021P | 2011-11-21 | 2011-11-21 | |
| US61/562,021 | 2011-11-21 | ||
| PCT/US2012/066139 WO2013078244A1 (en) | 2011-11-21 | 2012-11-20 | Carboxy x rhodamine analogs |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017183422A Division JP6574821B2 (ja) | 2011-11-21 | 2017-09-25 | カルボキシｘローダミン類似体 |
| JP2018213096A Division JP7227741B2 (ja) | 2011-11-21 | 2018-11-13 | カルボキシｘローダミン類似体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014534261A JP2014534261A (ja) | 2014-12-18 |
| JP2014534261A5 true JP2014534261A5 (enExample) | 2017-11-16 |
| JP6522339B2 JP6522339B2 (ja) | 2019-05-29 |
Family
ID=47324436
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014543546A Active JP6522339B2 (ja) | 2011-11-21 | 2012-11-20 | カルボキシｘローダミン類似体 |
| JP2017183422A Active JP6574821B2 (ja) | 2011-11-21 | 2017-09-25 | カルボキシｘローダミン類似体 |
| JP2018213096A Active JP7227741B2 (ja) | 2011-11-21 | 2018-11-13 | カルボキシｘローダミン類似体 |
| JP2020209163A Pending JP2021063089A (ja) | 2011-11-21 | 2020-12-17 | カルボキシｘローダミン類似体 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017183422A Active JP6574821B2 (ja) | 2011-11-21 | 2017-09-25 | カルボキシｘローダミン類似体 |
| JP2018213096A Active JP7227741B2 (ja) | 2011-11-21 | 2018-11-13 | カルボキシｘローダミン類似体 |
| JP2020209163A Pending JP2021063089A (ja) | 2011-11-21 | 2020-12-17 | カルボキシｘローダミン類似体 |
Country Status (4)
| Country | Link |
|---|---|
| US (3) | US9056885B2 (enExample) |
| EP (1) | EP2782916B1 (enExample) |
| JP (4) | JP6522339B2 (enExample) |
| WO (1) | WO2013078244A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3141905B1 (en) | 2008-03-27 | 2019-03-06 | Promega Corporation | Protein labeling with cyanobenzothiazole conjugates |
| EP2782916B1 (en) * | 2011-11-21 | 2018-02-28 | Promega Corporation | Carboxy x rhodamine analogs |
| WO2014052653A1 (en) * | 2012-09-26 | 2014-04-03 | Promega Corporation | Real-time monitoring |
| US10067149B2 (en) | 2012-12-12 | 2018-09-04 | Promega Corporation | Recognition of cellular target binding by a bioactive agent using intracellular bioluminescence resonance energy transfer |
| US10024862B2 (en) | 2012-12-12 | 2018-07-17 | Promega Corporation | Recognition of cellular target binding by a bioactive agent using intracellular bioluminescence resonance energy transfer |
| WO2014152298A1 (en) | 2013-03-15 | 2014-09-25 | Promega Corporation | New silicon and germanium dyes for use in genetic identity |
| US9938523B2 (en) | 2013-03-15 | 2018-04-10 | Arizona Board Of Regents On Behalf Of Arizona State University | Nucleic acid-tagged compositions and methods for multiplexed protein-protein interaction profiling |
| US11072811B2 (en) | 2013-03-15 | 2021-07-27 | Promega Corporation | Substrates for covalent tethering of proteins to functional groups or solid surfaces |
| EP3502693A1 (en) * | 2014-05-16 | 2019-06-26 | Life Technologies Corporation | Cell tracking reagents and their methods of use |
| JP6802841B2 (ja) | 2015-10-02 | 2020-12-23 | プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ | ローダミン色素の合成方法 |
| JP7200102B2 (ja) * | 2016-11-01 | 2023-01-06 | プロメガ コーポレイション | エネルギー受容体に係留されたセレンテラジン類縁体 |
| DK3548492T5 (en) | 2016-12-01 | 2024-08-05 | Promega Corp | Cell impermeable coelenterazine analogues |
| JP7161760B2 (ja) * | 2017-02-03 | 2022-10-27 | 国立大学法人東北大学 | 複素環化合物 |
| WO2019213119A1 (en) | 2018-05-01 | 2019-11-07 | Promega Corporation | Coelenterazine compounds as nanoluc suicide substrates |
| US11442063B2 (en) | 2018-05-30 | 2022-09-13 | Promega Corporation | Broad spectrum kinase binding agents |
| JP7703446B2 (ja) | 2018-11-28 | 2025-07-07 | プロメガ コーポレイション | 反応性ペプチド標識付け |
| SG11202106121SA (en) * | 2018-12-20 | 2021-07-29 | Life Technologies Corp | Asymmetric rhodamine dye and use thereof in biological assays |
| JP7584433B2 (ja) | 2019-03-20 | 2024-11-15 | プロメガ コーポレイション | 光親和性プローブ |
| BR112022010153A2 (pt) | 2019-11-27 | 2022-08-09 | Promega Corp | Peptídeos, ácido nucleico, polipeptídeo, composição, complexo bioluminescente, métodos, dipeptídeo, sistema e kit |
| EP4073512B1 (en) | 2019-12-10 | 2025-11-12 | Promega Corporation | Compositions and methods for bioluminescent detection using multifunctional probes |
| US20220064696A1 (en) | 2020-08-28 | 2022-03-03 | Promega Corporation | Target engagement assay for ras proteins |
| US20220195518A1 (en) * | 2020-12-22 | 2022-06-23 | Illumina Cambridge Limited | Methods and compositions for nucleic acid sequencing |
| WO2024263837A2 (en) * | 2023-06-22 | 2024-12-26 | Promega Corporation | Compounds and methods of use thereof for assessing target engagement for dna polymerase theta |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES258418A1 (es) * | 1959-05-28 | 1960-11-16 | Geigy Ag J R | Procedimiento para la prepaarcion de nuevos derivados de iminodibencilo |
| US5171534A (en) | 1984-01-16 | 1992-12-15 | California Institute Of Technology | Automated DNA sequencing technique |
| CA1340806C (en) | 1986-07-02 | 1999-11-02 | James Merrill Prober | Method, system and reagents for dna sequencing |
| US4900686A (en) * | 1987-04-02 | 1990-02-13 | Polaroid Corporation | Fluorescent conjugates and biological diagnostic assay |
| US4965349A (en) * | 1987-12-24 | 1990-10-23 | Applied Biosystems, Inc. | Method of synthesizing oligonucleotides labeled with ammonia-labile groups on solid phase supports |
| US4997928A (en) | 1988-09-15 | 1991-03-05 | E. I. Du Pont De Nemours And Company | Fluorescent reagents for the preparation of 5'-tagged oligonucleotides |
| US5304644A (en) * | 1992-04-15 | 1994-04-19 | G. D. Searle & Co. | 1-,2-,3-,4-,5-,6-,7-,8- and/or 9 substituted dibenzoxazepine compounds, pharmaceutical compositions and methods for treating pain |
| WO1994005688A1 (en) | 1992-09-03 | 1994-03-17 | Applied Biosystems, Inc. | 4,7-dichlorofluorescein dyes as molecular probes |
| US5658751A (en) | 1993-04-13 | 1997-08-19 | Molecular Probes, Inc. | Substituted unsymmetrical cyanine dyes with selected permeability |
| US6080852A (en) * | 1996-06-27 | 2000-06-27 | The Perkin-Elmer Corporation | 4,7-dichlororhodamine dyes |
| US5936087A (en) * | 1997-11-25 | 1999-08-10 | The Perkin-Elmer Corporation | Dibenzorhodamine dyes |
| US6583168B1 (en) | 1997-11-25 | 2003-06-24 | Applera Corporation | Sulfonated diarylrhodamine dyes |
| WO2000007992A1 (en) * | 1998-08-04 | 2000-02-17 | Toray Industries, Inc. | Fused benzene heterocycle derivatives and utilization thereof |
| US6403860B1 (en) | 1999-03-25 | 2002-06-11 | Pioneer Hi-Bred International, Inc. | Ku80 homologue and uses thereof |
| US6248884B1 (en) * | 1999-06-03 | 2001-06-19 | The Perkin-Elmer Corporation | Extended rhodamine compounds useful as fluorescent labels |
| ES2291507T3 (es) | 2001-10-19 | 2008-03-01 | MERCK & CO., INC. | Moduladores de receptor de androgenos y procedimientos de uso de los mismos. |
| AU2003211951A1 (en) | 2002-02-14 | 2003-09-04 | Ono Pharmaceutical Co., Ltd. | N-carbamoyl nitrogen-containing fused ring compounds and drugs containing these compounds as the active ingredient |
| EP1594962B1 (en) | 2003-01-31 | 2014-08-27 | Promega Corporation | Covalent tethering of functional groups to proteins |
| AU2004242249A1 (en) | 2003-05-23 | 2004-12-02 | Epfl-Ecole Polytechnique Federale De Lausanne | Methods for protein labeling based on acyl carrier protein |
| US7667024B2 (en) | 2003-11-19 | 2010-02-23 | Allelogic Biosciences Corp. | Oligonucleotides labeled with a plurality of fluorophores |
| EP1882688A1 (en) | 2006-07-25 | 2008-01-30 | EPFL Ecole Polytechnique Fédérale de Lausanne | Labelling of fusion proteins with synthetic probes |
| CN101184082B (zh) | 2006-11-17 | 2011-04-20 | 华为技术有限公司 | 群组用户注册方法、状态更新方法、处理装置、ims网络实体和通信系统 |
| EP3141905B1 (en) | 2008-03-27 | 2019-03-06 | Promega Corporation | Protein labeling with cyanobenzothiazole conjugates |
| US20110130384A1 (en) | 2008-06-25 | 2011-06-02 | Takeda Pharmaceutical Company Limited | Amide compound |
| KR101665352B1 (ko) | 2009-05-01 | 2016-10-12 | 프로메가 코포레이션 | 광 출력이 향상된 합성 오플로포러스 루시퍼라제 |
| AU2011323418B2 (en) | 2010-11-02 | 2017-07-27 | Promega Corporation | Novel coelenterazine substrates and methods of use |
| EP2782916B1 (en) * | 2011-11-21 | 2018-02-28 | Promega Corporation | Carboxy x rhodamine analogs |
| KR102272233B1 (ko) * | 2012-12-12 | 2021-07-01 | 프로메가 코포레이션 | 생체활성 제제의 세포 표적 포획을 위한 조성물 및 방법 |
-
2012
- 2012-11-20 EP EP12798535.6A patent/EP2782916B1/en active Active
- 2012-11-20 WO PCT/US2012/066139 patent/WO2013078244A1/en not_active Ceased
- 2012-11-20 JP JP2014543546A patent/JP6522339B2/ja active Active
- 2012-11-20 US US13/682,589 patent/US9056885B2/en active Active
-
2015
- 2015-05-28 US US14/724,111 patent/US10139400B2/en active Active
-
2016
- 2016-07-07 US US15/204,664 patent/US10215751B2/en active Active
-
2017
- 2017-09-25 JP JP2017183422A patent/JP6574821B2/ja active Active
-
2018
- 2018-11-13 JP JP2018213096A patent/JP7227741B2/ja active Active
-
2020
- 2020-12-17 JP JP2020209163A patent/JP2021063089A/ja active Pending
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