JP2014533518A5 - - Google Patents

Info

Publication number

JP2014533518A5

JP2014533518A5 JP2014542951A JP2014542951A JP2014533518A5 JP 2014533518 A5 JP2014533518 A5 JP 2014533518A5 JP 2014542951 A JP2014542951 A JP 2014542951A JP 2014542951 A JP2014542951 A JP 2014542951A JP 2014533518 A5 JP2014533518 A5 JP 2014533518A5

Authority

JP

Japan

Prior art keywords

polypeptide

ugt

seq

amino acid

set forth

Prior art date

2012-11-19

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

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• 108090000765 processed proteins & peptides Proteins 0.000 claims 35
• 229920001184 polypeptide Polymers 0.000 claims 31
• 102000004196 processed proteins & peptides Human genes 0.000 claims 31
• 150000001413 amino acids Chemical group 0.000 claims 15
• 238000000034 method Methods 0.000 claims 13
• 229930189775 mogroside Natural products 0.000 claims 9
• 150000001875 compounds Chemical class 0.000 claims 7
• 239000013592 cell lysate Substances 0.000 claims 4
• 239000013604 expression vector Substances 0.000 claims 4
• 230000001279 glycosylating effect Effects 0.000 claims 4
• JLYBBRAAICDTIS-AYEHCKLZSA-N mogrol Chemical compound C([C@H]1[C@]2(C)CC[C@@H]([C@]2(C[C@@H](O)[C@]11C)C)[C@@H](CC[C@@H](O)C(C)(C)O)C)C=C2[C@H]1CC[C@H](O)C2(C)C JLYBBRAAICDTIS-AYEHCKLZSA-N 0.000 claims 4
• JLYBBRAAICDTIS-UHFFFAOYSA-N mogrol Natural products CC12C(O)CC3(C)C(C(CCC(O)C(C)(C)O)C)CCC3(C)C1CC=C1C2CCC(O)C1(C)C JLYBBRAAICDTIS-UHFFFAOYSA-N 0.000 claims 4
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
• 101100483369 Arabidopsis thaliana UGT73C3 gene Proteins 0.000 claims 3
• 101100483372 Arabidopsis thaliana UGT73C5 gene Proteins 0.000 claims 3
• 101100483373 Arabidopsis thaliana UGT73C6 gene Proteins 0.000 claims 3
• 102000000340 Glucosyltransferases Human genes 0.000 claims 3
• 108010055629 Glucosyltransferases Proteins 0.000 claims 3
• 101100483376 Stevia rebaudiana UGT73E1 gene Proteins 0.000 claims 3
• 101100048059 Stevia rebaudiana UGT85C2 gene Proteins 0.000 claims 3
• 230000001419 dependent effect Effects 0.000 claims 3
• 102000005720 Glutathione transferase Human genes 0.000 claims 2
• 108010070675 Glutathione transferase Proteins 0.000 claims 2
• 108010043121 Green Fluorescent Proteins Proteins 0.000 claims 2
• 102000004144 Green Fluorescent Proteins Human genes 0.000 claims 2
• 241000700605 Viruses Species 0.000 claims 2
• 210000004027 cell Anatomy 0.000 claims 2
• 230000013595 glycosylation Effects 0.000 claims 2
• 238000006206 glycosylation reaction Methods 0.000 claims 2
• 239000005090 green fluorescent protein Substances 0.000 claims 2
• 239000013612 plasmid Substances 0.000 claims 2
• 108010073178 Glucan 1,4-alpha-Glucosidase Proteins 0.000 claims 1
• 241000238631 Hexapoda Species 0.000 claims 1
• 108010076504 Protein Sorting Signals Proteins 0.000 claims 1
• 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
• 108010031100 chloroplast transit peptides Proteins 0.000 claims 1
• 210000004962 mammalian cell Anatomy 0.000 claims 1
• 238000004519 manufacturing process Methods 0.000 claims 1
• 244000005700 microbiome Species 0.000 claims 1
• 230000002438 mitochondrial effect Effects 0.000 claims 1
• 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
• 238000003259 recombinant expression Methods 0.000 claims 1
• 230000028327 secretion Effects 0.000 claims 1
• 238000003786 synthesis reaction Methods 0.000 claims 1
• 241001515965 unidentified phage Species 0.000 claims 1
• 230000003612 virological effect Effects 0.000 claims 1