JP2014532072A - 眼疾患の治療 - Google Patents
眼疾患の治療 Download PDFInfo
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2019531259A (ja) * | 2016-07-20 | 2019-10-31 | エアーピオ セラピューティクス インコーポレイテッド | ＶＥ−ＰＴＰ（ＨＰＴＰ−β）を標的化するヒト化モノクローナル抗体 |
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| US7622593B2 (en) | 2006-06-27 | 2009-11-24 | The Procter & Gamble Company | Human protein tyrosine phosphatase inhibitors and methods of use |
| PL2451279T3 (pl) | 2009-07-06 | 2019-09-30 | Aerpio Therapeutics, Inc. | Pochodne benzosulfonamidowe, ich kompozycje i ich zastosowanie w zapobieganiu przerzutom komórek nowotworowych |
| RS54010B1 (sr) | 2009-11-06 | 2015-10-30 | Aerpio Therapeutics Inc. | Inhibitori prolil hidroksilaze |
| AU2012323856B2 (en) | 2011-10-13 | 2017-05-25 | EyePoint Pharmaceuticals, Inc. | Methods for treating Vascular Leak Syndrome and cancer |
| HK1201196A1 (en) | 2011-10-13 | 2015-08-28 | Aerpio Therapeutics, Inc. | Treatment of ocular disease |
| US20150050277A1 (en) | 2013-03-15 | 2015-02-19 | Aerpio Therapeutics Inc. | Compositions and methods for treating ocular diseases |
| EP4101297A1 (en) | 2013-03-15 | 2022-12-14 | Aerpio Pharmaceuticals, Inc. | Compositions, formulations and methods for treating ocular diseases |
| KR102266819B1 (ko) | 2013-04-29 | 2021-06-18 | 에프. 호프만-라 로슈 아게 | Fc-수용체 결합 개질된 비대칭 항체 및 이의 사용 방법 |
| CA2931979A1 (en) * | 2014-01-15 | 2015-07-23 | F. Hoffmann-La Roche Ag | Fc-region variants with modified fcrn-binding properties |
| RU2698969C2 (ru) | 2014-01-15 | 2019-09-02 | Ф.Хоффманн-Ля Рош Аг | Варианты fc-области с улучшенной способностью связываться с белком а |
| CN106232120B (zh) | 2014-02-19 | 2021-01-08 | 爱尔皮奥治疗有限公司 | 制备n-苄基-3-羟基-4-取代的-吡啶-2-(1h)-酮的方法 |
| US9994560B2 (en) | 2014-03-14 | 2018-06-12 | Aerpio Therapeutics, Inc. | HPTP-β inhibitors |
| WO2016022813A1 (en) | 2014-08-07 | 2016-02-11 | Aerpio Therapeutics, Inc. | Combination of immunotherapies with activators of tie-2 |
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| CN113713101B (zh) | 2015-09-23 | 2023-07-28 | 视点制药公司 | 用tie-2的激活剂治疗眼内压的方法 |
| CN109996440A (zh) * | 2016-10-21 | 2019-07-09 | 曼宁研究有限公司 | Ve-ptp敲除 |
| CN106491911A (zh) * | 2016-10-24 | 2017-03-15 | 严成 | 一种治疗脉络膜血管瘤的中药 |
| US10894824B2 (en) | 2018-09-24 | 2021-01-19 | Aerpio Pharmaceuticals, Inc. | Multispecific antibodies that target HPTP-β (VE-PTP) and VEGF |
| WO2020223209A1 (en) | 2019-04-29 | 2020-11-05 | Aerpio Pharmaceuticals, Inc. | Tie-2 activators targeting the schlemm's canal |
| GB2589400A (en) | 2019-06-24 | 2021-06-02 | Aerpio Pharmaceuticals Inc | Formulations of tie-2 activators and methods of use thereof |
| EP4010370A1 (en) * | 2019-08-06 | 2022-06-15 | F. Hoffmann-La Roche AG | Personalized treatment of ophthalmologic diseases |
| CN112322719A (zh) * | 2020-11-06 | 2021-02-05 | 温州医科大学 | 循环血外泌体miRNA作为视网膜静脉阻塞疾病诊断标志物中的应用 |
| KR20250010199A (ko) * | 2023-07-11 | 2025-01-21 | 재단법인 아산사회복지재단 | Tie2을 과발현하는 혈관내피세포를 포함하는 망막 내 혈관신생 질환 예방 또는 치료용 조성물 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019531259A (ja) * | 2016-07-20 | 2019-10-31 | エアーピオ セラピューティクス インコーポレイテッド | ＶＥ−ＰＴＰ（ＨＰＴＰ−β）を標的化するヒト化モノクローナル抗体 |
| JP7107914B2 (ja) | 2016-07-20 | 2022-07-27 | アイポイント ファーマシューティカルズ， インコーポレイテッド | ＶＥ－ＰＴＰ（ＨＰＴＰ－β）を標的化するヒト化モノクローナル抗体 |
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| ES2774972T3 (es) | 2020-07-23 |
| JP2018131467A (ja) | 2018-08-23 |
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| EP2766044B1 (en) | 2019-12-11 |
| WO2013056233A1 (en) | 2013-04-18 |
| HK1201438A1 (en) | 2015-09-04 |
| US10329357B2 (en) | 2019-06-25 |
| EP3501536A1 (en) | 2019-06-26 |
| BR112014008759A2 (pt) | 2017-06-13 |
| AU2012323849B2 (en) | 2017-04-20 |
| EP2766044A1 (en) | 2014-08-20 |
| CA2850824C (en) | 2023-01-03 |
| JP6259503B2 (ja) | 2018-01-10 |
| CA2850824A1 (en) | 2013-04-18 |
| AU2012323849A1 (en) | 2014-04-17 |
| BR112014008759A8 (pt) | 2017-09-12 |
| MX347226B (es) | 2017-04-19 |
| CN104066448A (zh) | 2014-09-24 |
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