BR112014008759A2 - tratamento de doença ocular - Google Patents

tratamento de doença ocular

Info

Publication number
BR112014008759A2
BR112014008759A2 BR112014008759A BR112014008759A BR112014008759A2 BR 112014008759 A2 BR112014008759 A2 BR 112014008759A2 BR 112014008759 A BR112014008759 A BR 112014008759A BR 112014008759 A BR112014008759 A BR 112014008759A BR 112014008759 A2 BR112014008759 A2 BR 112014008759A2
Authority
BR
Brazil
Prior art keywords
macular edema
eye disease
vascular
disease treatment
diabetic
Prior art date
Application number
BR112014008759A
Other languages
English (en)
Other versions
BR112014008759A8 (pt
Inventor
Peters Kevin
Shalwitz Robert
Original Assignee
Aerpio Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aerpio Therapeutics Inc filed Critical Aerpio Therapeutics Inc
Publication of BR112014008759A2 publication Critical patent/BR112014008759A2/pt
Publication of BR112014008759A8 publication Critical patent/BR112014008759A8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

abstract: disclosed are methods for treating eye diseases or conditions characterized by vascular instability, vascular leakage, and neovacularization such as diabetic macular edema, age-related macular edema, choroidal neovascularization, diabetic retinopathy, trauma, ocular ischemia, and uveitis. ------------------------------------------------------------------------------------------ tradução do resumo resumo patente de invenção: "tratamento de doença ocular". são divulgados métodos para o tratamento de doenças ou condições oculares caracterizadas por instabilidade vascular, vaza-mento vascular e neovascularização, tal como o edema macular diabé-tico, edema macular relacionada à idade, neovascularização de coroide, retinopatia diabética, trauma, isquemia ocular e uveíte.
BR112014008759A 2011-10-13 2012-10-15 Tratamento de doença ocular BR112014008759A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161546708P 2011-10-13 2011-10-13
PCT/US2012/060263 WO2013056233A1 (en) 2011-10-13 2012-10-15 Treatment of ocular disease

Publications (2)

Publication Number Publication Date
BR112014008759A2 true BR112014008759A2 (pt) 2017-06-13
BR112014008759A8 BR112014008759A8 (pt) 2017-09-12

Family

ID=48082580

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014008759A BR112014008759A8 (pt) 2011-10-13 2012-10-15 Tratamento de doença ocular

Country Status (11)

Country Link
US (5) US8999325B2 (pt)
EP (2) EP2766044B1 (pt)
JP (5) JP2014532072A (pt)
CN (2) CN107080843A (pt)
AU (1) AU2012323849B2 (pt)
BR (1) BR112014008759A8 (pt)
CA (1) CA2850824C (pt)
ES (1) ES2774972T3 (pt)
HK (2) HK1201196A1 (pt)
MX (1) MX347226B (pt)
WO (1) WO2013056233A1 (pt)

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Also Published As

Publication number Publication date
JP2016210811A (ja) 2016-12-15
JP2018131466A (ja) 2018-08-23
MX347226B (es) 2017-04-19
HK1201438A1 (en) 2015-09-04
JP2014532072A (ja) 2014-12-04
ES2774972T3 (es) 2020-07-23
AU2012323849B2 (en) 2017-04-20
WO2013056233A1 (en) 2013-04-18
US20130095105A1 (en) 2013-04-18
US20180044432A1 (en) 2018-02-15
JP2018131467A (ja) 2018-08-23
EP2766044A4 (en) 2015-06-10
HK1201196A1 (en) 2015-08-28
BR112014008759A8 (pt) 2017-09-12
EP2766044B1 (en) 2019-12-11
US8999325B2 (en) 2015-04-07
MX2014004449A (es) 2014-11-10
CN107080843A (zh) 2017-08-22
US10329357B2 (en) 2019-06-25
US20200231703A1 (en) 2020-07-23
JP2016210812A (ja) 2016-12-15
NZ623275A (en) 2016-05-27
CA2850824A1 (en) 2013-04-18
CA2850824C (en) 2023-01-03
US20150232575A1 (en) 2015-08-20
AU2012323849A1 (en) 2014-04-17
CN104066448A (zh) 2014-09-24
EP3501536A1 (en) 2019-06-26
EP2766044A1 (en) 2014-08-20
US20200010565A1 (en) 2020-01-09
JP6259503B2 (ja) 2018-01-10

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