JP2014532060A5 - - Google Patents

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Publication number
JP2014532060A5
JP2014532060A5 JP2014534626A JP2014534626A JP2014532060A5 JP 2014532060 A5 JP2014532060 A5 JP 2014532060A5 JP 2014534626 A JP2014534626 A JP 2014534626A JP 2014534626 A JP2014534626 A JP 2014534626A JP 2014532060 A5 JP2014532060 A5 JP 2014532060A5
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JP
Japan
Prior art keywords
alkyl
substituted
heterocycloalkyl
halo
haloalkyl
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2014534626A
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English (en)
Japanese (ja)
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JP2014532060A (ja
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Priority claimed from PCT/US2012/058298 external-priority patent/WO2013052417A1/en
Publication of JP2014532060A publication Critical patent/JP2014532060A/ja
Publication of JP2014532060A5 publication Critical patent/JP2014532060A5/ja
Pending legal-status Critical Current

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JP2014534626A 2011-10-03 2012-10-01 癌を治療するためのピロロピリミジン化合物 Pending JP2014532060A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161542392P 2011-10-03 2011-10-03
US61/542,392 2011-10-03
US201161547183P 2011-10-14 2011-10-14
US61/547,183 2011-10-14
PCT/US2012/058298 WO2013052417A1 (en) 2011-10-03 2012-10-01 Pyrrolopyrimidine compounds for the treatment of cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016255095A Division JP6316925B2 (ja) 2011-10-03 2016-12-28 癌を治療するためのピロロピリミジン化合物

Publications (2)

Publication Number Publication Date
JP2014532060A JP2014532060A (ja) 2014-12-04
JP2014532060A5 true JP2014532060A5 (enExample) 2016-03-03

Family

ID=48044101

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2014534626A Pending JP2014532060A (ja) 2011-10-03 2012-10-01 癌を治療するためのピロロピリミジン化合物
JP2016255095A Active JP6316925B2 (ja) 2011-10-03 2016-12-28 癌を治療するためのピロロピリミジン化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2016255095A Active JP6316925B2 (ja) 2011-10-03 2016-12-28 癌を治療するためのピロロピリミジン化合物

Country Status (13)

Country Link
US (3) US9273056B2 (enExample)
EP (1) EP2763988B1 (enExample)
JP (2) JP2014532060A (enExample)
KR (1) KR102063098B1 (enExample)
CN (1) CN103958510B (enExample)
AU (1) AU2012318896B2 (enExample)
BR (1) BR112014007788A2 (enExample)
CA (1) CA2850617A1 (enExample)
ES (1) ES2650630T3 (enExample)
IL (1) IL231835A0 (enExample)
MX (1) MX2014004086A (enExample)
RU (1) RU2631655C2 (enExample)
WO (1) WO2013052417A1 (enExample)

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EP2571361A4 (en) 2010-05-19 2013-11-13 Univ North Carolina PYRAZOLOPYRIMIDINE COMPOUNDS FOR CANCER TREATMENT
CN103958510B (zh) 2011-10-03 2016-10-19 北卡罗来纳大学教堂山分校 用于治疗癌症的吡咯并嘧啶化合物
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EP2925752A4 (en) 2012-11-27 2016-06-01 Univ North Carolina PYRIMIDINE COMPOUNDS FOR CANCER TREATMENT
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KR102163494B1 (ko) * 2018-10-26 2020-10-08 한국과학기술연구원 단백질 키나아제 저해제인 헤테로방향족 매크로시클릭 유도체
KR102848297B1 (ko) * 2019-04-02 2025-08-20 메릭스 인코포레이티드 키나아제 억제제의 다형체, 이러한 화합물을 함유하는 약학 조성물, 제조 방법 및 용도
JP2023516441A (ja) 2020-03-06 2023-04-19 インサイト・コーポレイション Ａｘｌ／ｍｅｒ阻害剤及びｐｄ－１／ｐｄ－ｌ１阻害剤を含む併用療法
CN112043710A (zh) * 2020-09-28 2020-12-08 广州智睿医药科技有限公司 一种治疗或预防与lrrk2激酶或异常lrrk2突变激酶活性相关疾病的药物
CN115073469B (zh) * 2021-03-15 2023-12-22 药雅科技(上海)有限公司 吡咯并嘧啶类化合物作为激酶抑制剂的制备及其应用
WO2025170773A1 (en) * 2024-01-26 2025-08-14 The University Of North Carolina At Chapel Hill Tam-family degraders and uses thereof

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BR112014028424A2 (pt) 2012-05-22 2018-04-24 Univ North Carolina Chapel Hill compostos de pirimidina para o tratamento de câncer
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EP2925752A4 (en) 2012-11-27 2016-06-01 Univ North Carolina PYRIMIDINE COMPOUNDS FOR CANCER TREATMENT
US20170202847A1 (en) 2014-04-04 2017-07-20 The University Of North Carolina At Chapel Hill Methods for the treatment of tumors
CA2945128A1 (en) 2014-04-11 2015-10-15 The University Of North Carolina At Chapel Hill Mertk-specific pyrimidine compounds

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