JP2014531434A5 - - Google Patents

Download PDF

Info

Publication number
JP2014531434A5
JP2014531434A5 JP2014529919A JP2014529919A JP2014531434A5 JP 2014531434 A5 JP2014531434 A5 JP 2014531434A5 JP 2014529919 A JP2014529919 A JP 2014529919A JP 2014529919 A JP2014529919 A JP 2014529919A JP 2014531434 A5 JP2014531434 A5 JP 2014531434A5
Authority
JP
Japan
Prior art keywords
optionally substituted
substituted
contrast component
contrast
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2014529919A
Other languages
English (en)
Japanese (ja)
Other versions
JP6174026B2 (ja
JP2014531434A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2012/054309 external-priority patent/WO2013036869A2/en
Publication of JP2014531434A publication Critical patent/JP2014531434A/ja
Publication of JP2014531434A5 publication Critical patent/JP2014531434A5/ja
Priority to JP2017131851A priority Critical patent/JP6964450B2/ja
Application granted granted Critical
Publication of JP6174026B2 publication Critical patent/JP6174026B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2014529919A 2011-09-09 2012-09-07 造影剤の合成および使用のための組成物、方法およびシステム Active JP6174026B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2017131851A JP6964450B2 (ja) 2011-09-09 2017-07-05 造影剤の合成および使用のための組成物、方法およびシステム

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161533133P 2011-09-09 2011-09-09
US61/533,133 2011-09-09
US201261656492P 2012-06-06 2012-06-06
US201261656489P 2012-06-06 2012-06-06
US61/656,489 2012-06-06
US61/656,492 2012-06-06
PCT/US2012/054309 WO2013036869A2 (en) 2011-09-09 2012-09-07 Compositions, methods, and systems for the synthesis and use of imaging agents

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017131851A Division JP6964450B2 (ja) 2011-09-09 2017-07-05 造影剤の合成および使用のための組成物、方法およびシステム

Publications (3)

Publication Number Publication Date
JP2014531434A JP2014531434A (ja) 2014-11-27
JP2014531434A5 true JP2014531434A5 (cg-RX-API-DMAC7.html) 2015-11-05
JP6174026B2 JP6174026B2 (ja) 2017-08-02

Family

ID=47832802

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2014529919A Active JP6174026B2 (ja) 2011-09-09 2012-09-07 造影剤の合成および使用のための組成物、方法およびシステム
JP2017131851A Expired - Fee Related JP6964450B2 (ja) 2011-09-09 2017-07-05 造影剤の合成および使用のための組成物、方法およびシステム
JP2019147621A Withdrawn JP2019218371A (ja) 2011-09-09 2019-08-09 造影剤の合成および使用のための組成物、方法およびシステム

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2017131851A Expired - Fee Related JP6964450B2 (ja) 2011-09-09 2017-07-05 造影剤の合成および使用のための組成物、方法およびシステム
JP2019147621A Withdrawn JP2019218371A (ja) 2011-09-09 2019-08-09 造影剤の合成および使用のための組成物、方法およびシステム

Country Status (15)

Country Link
US (5) US9550000B2 (cg-RX-API-DMAC7.html)
EP (2) EP2753605B1 (cg-RX-API-DMAC7.html)
JP (3) JP6174026B2 (cg-RX-API-DMAC7.html)
KR (4) KR101946089B1 (cg-RX-API-DMAC7.html)
CN (2) CN104159890B (cg-RX-API-DMAC7.html)
AU (3) AU2012304359B2 (cg-RX-API-DMAC7.html)
BR (2) BR122019017259B1 (cg-RX-API-DMAC7.html)
CA (2) CA3123737A1 (cg-RX-API-DMAC7.html)
DK (1) DK2753605T3 (cg-RX-API-DMAC7.html)
ES (1) ES2731471T3 (cg-RX-API-DMAC7.html)
IL (2) IL231414B (cg-RX-API-DMAC7.html)
SG (2) SG2014013767A (cg-RX-API-DMAC7.html)
TW (2) TWI700268B (cg-RX-API-DMAC7.html)
WO (1) WO2013036869A2 (cg-RX-API-DMAC7.html)
ZA (2) ZA201401940B (cg-RX-API-DMAC7.html)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7344702B2 (en) 2004-02-13 2008-03-18 Bristol-Myers Squibb Pharma Company Contrast agents for myocardial perfusion imaging
US8563573B2 (en) 2007-11-02 2013-10-22 Vertex Pharmaceuticals Incorporated Azaindole derivatives as CFTR modulators
EP2474523B1 (en) 2006-12-26 2020-04-08 Lantheus Medical Imaging, Inc. Ligands for imaging cardiac innervation
ES2767973T3 (es) 2008-02-29 2020-06-19 Lantheus Medical Imaging Inc Agentes de contraste para aplicaciones que comprenden formación de imágenes de perfusión
JP5662416B2 (ja) 2009-04-15 2015-01-28 ランセウス メディカル イメージング, インコーポレイテッド アスコルビン酸による放射性医薬組成物の安定化
BR112012019789A2 (pt) 2010-02-08 2016-08-09 Lantheus Medical Imaging Inc métodos e aparelhos para sintetizar agentes de imagiologia, e seus intermediários
US8802868B2 (en) 2010-03-25 2014-08-12 Vertex Pharmaceuticals Incorporated Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxo1-5-yl)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan2-yl)-1H-Indol-5-yl)-Cyclopropanecarboxamide
MX353408B (es) 2010-04-22 2018-01-11 Vertex Pharma Proceso para producir compuestos de cicloalquilcarboxamido-indol.
WO2011143360A2 (en) 2010-05-11 2011-11-17 Lantheus Medical Imaging, Inc. Compositions, methods and systems for the synthesis and use of imaging agents
US20140328757A1 (en) * 2011-10-21 2014-11-06 Lantheus Medical Imaging, Inc. Compositions comprising ascorbic acid and an imaging agent and related methods
CN104244991A (zh) 2012-04-10 2014-12-24 蓝瑟斯医学影像公司 放射性药物合成方法
AU2013203000B9 (en) 2012-08-10 2017-02-02 Lantheus Medical Imaging, Inc. Compositions, methods, and systems for the synthesis and use of imaging agents
CN104936512A (zh) 2013-01-24 2015-09-23 泰勒顿国际控股公司 身体结构成像
WO2015033319A2 (en) 2013-09-08 2015-03-12 Shlomo Ben-Haim Apparatus and methods for diagnosis and treatment of patterns of nervous system activity affecting disease
DK3054936T5 (da) 2013-10-10 2024-03-18 Eastern Virginia Medical School 4-((2-hydroxy-3-methoxybenzyl)amino) benzensulfonamid derivater som 12-lipoxygenase inhibitorer
US10646183B2 (en) 2014-01-10 2020-05-12 Tylerton International Inc. Detection of scar and fibrous cardiac zones
MX387720B (es) 2014-04-15 2025-03-12 Vertex Pharma Composiciones farmacéuticas para el tratamiento de enfermedades mediadas por el regulador de conductancia de transmembrana de fibrosis quística.
US10918742B2 (en) 2016-03-25 2021-02-16 Nanoprobes, Inc. Iodine-based particles
JP6060302B1 (ja) * 2016-06-10 2017-01-11 日本メジフィジックス株式会社 心筋核医学画像データの解析方法及び解析装置
PT3971177T (pt) 2016-07-20 2024-07-30 Novartis Ag Derivados de aminopiridina e a sua utilização como inibidores seletivos de alk-2
US11666888B2 (en) 2018-02-05 2023-06-06 Bio-Rad Laboratories, Inc. Chromatography resin having an anionic exchange-hydrophobic mixed mode ligand
WO2020030954A1 (en) 2018-08-09 2020-02-13 Integrative Medicine Clinic, Sia Theranostics-like protein sanps conjugated to integrin and pmsa targeting peptides and therapy of prostate cancer
WO2020061101A1 (en) 2018-09-18 2020-03-26 Nikang Therapeutics, Inc. Tri-substituted heteroaryl derivatives as src homology-2 phosphatase inhibitors
EP3682906A1 (en) * 2019-01-17 2020-07-22 Julius-Maximilians-Universität Würzburg Compound targeting norepinephrine transporter
JP7717065B2 (ja) 2019-11-22 2025-08-01 インサイト コーポレーション Alk2阻害剤及びjak2阻害剤を含む併用療法
WO2021138391A1 (en) 2019-12-30 2021-07-08 Tyra Biosciences, Inc. Indazole compounds
AU2021292484A1 (en) 2020-06-16 2023-01-19 Incyte Corporation ALK2 inhibitors for the treatment of anemia
US12264149B2 (en) 2020-12-30 2025-04-01 Tyra Biosciences, Inc. Indazole compounds as kinase inhibitors
EP4301747A4 (en) * 2021-03-02 2025-01-22 Mindset Pharma Inc. Indole derivatives as serotonergic agents useful for the treatment of disorders related thereto
CN113292405B (zh) * 2021-06-01 2024-07-26 湖南华腾制药有限公司 一种2-溴-4氯苯甲醛的制备方法
CN113418940B (zh) * 2021-06-24 2023-03-14 电子科技大学 一种基于x射线示踪颗粒的检测方法及检测装置
CN113461567B (zh) * 2021-07-30 2023-08-22 长沙创新药物工业技术研究院有限公司 一种2-溴-4腈基苯甲醛的制备方法
EP4634186A1 (en) 2022-12-16 2025-10-22 Astrazeneca AB 2,6,9-trisubstituted purines
CN119978393B (zh) * 2025-04-14 2025-07-04 西南石油大学 一种具有氨基侧链交联的形状记忆聚芳醚腈复合材料及其制备方法和应用

Family Cites Families (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1125126A (en) * 1913-01-06 1915-01-19 Reinhold Krumming Temporary binder or loose-sheet holder.
FR1010218A (fr) 1949-02-10 1952-06-09 American Cyanamid Co Perfectionnements aux sels de guanidine
GB1215255A (en) 1968-03-13 1970-12-09 Pfizer & Co C Halophenylalkylguanidine compounds
US4270537A (en) 1979-11-19 1981-06-02 Romaine Richard A Automatic hypodermic syringe
US4596556A (en) 1985-03-25 1986-06-24 Bioject, Inc. Hypodermic injection apparatus
JPS61260018A (ja) 1985-05-14 1986-11-18 Nissan Chem Ind Ltd 抗アレルギ−剤
US4886499A (en) 1986-12-18 1989-12-12 Hoffmann-La Roche Inc. Portable injection appliance
GB8704027D0 (en) 1987-02-20 1987-03-25 Owen Mumford Ltd Syringe needle combination
US4940460A (en) 1987-06-19 1990-07-10 Bioject, Inc. Patient-fillable and non-invasive hypodermic injection device assembly
US4790824A (en) 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
US4941880A (en) 1987-06-19 1990-07-17 Bioject, Inc. Pre-filled ampule and non-invasive hypodermic injection device assembly
US5339163A (en) 1988-03-16 1994-08-16 Canon Kabushiki Kaisha Automatic exposure control device using plural image plane detection areas
FR2638359A1 (fr) 1988-11-03 1990-05-04 Tino Dalto Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau
US5312335A (en) 1989-11-09 1994-05-17 Bioject Inc. Needleless hypodermic injection device
US5064413A (en) 1989-11-09 1991-11-12 Bioject, Inc. Needleless hypodermic injection device
US5190521A (en) 1990-08-22 1993-03-02 Tecnol Medical Products, Inc. Apparatus and method for raising a skin wheal and anesthetizing skin
US5527288A (en) 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
GB9118204D0 (en) 1991-08-23 1991-10-09 Weston Terence E Needle-less injector
SE9102652D0 (sv) 1991-09-13 1991-09-13 Kabi Pharmacia Ab Injection needle arrangement
US5328483A (en) 1992-02-27 1994-07-12 Jacoby Richard M Intradermal injection device with medication and needle guard
US5383851A (en) 1992-07-24 1995-01-24 Bioject Inc. Needleless hypodermic injection device
US5569189A (en) 1992-09-28 1996-10-29 Equidyne Systems, Inc. hypodermic jet injector
US5334144A (en) 1992-10-30 1994-08-02 Becton, Dickinson And Company Single use disposable needleless injector
US5417959A (en) 1993-10-04 1995-05-23 Mallinckrodt Medical, Inc. Functionalized aza-crytand ligands for diagnostic imaging applications
US5493026A (en) 1993-10-25 1996-02-20 Organix, Inc. Substituted 2-carboxyalkyl-3-(fluorophenyl)-8-(3-halopropen-2-yl) nortropanes and their use as imaging for agents for neurodegenerative disorders
JPH07252236A (ja) 1994-01-28 1995-10-03 Takeda Chem Ind Ltd 抗癌剤
WO1995024176A1 (en) 1994-03-07 1995-09-14 Bioject, Inc. Ampule filling device
US5466220A (en) 1994-03-08 1995-11-14 Bioject, Inc. Drug vial mixing and transfer device
US5599302A (en) 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
US5730723A (en) 1995-10-10 1998-03-24 Visionary Medical Products Corporation, Inc. Gas pressured needle-less injection device and method
US5893397A (en) 1996-01-12 1999-04-13 Bioject Inc. Medication vial/syringe liquid-transfer apparatus
GB9607549D0 (en) 1996-04-11 1996-06-12 Weston Medical Ltd Spring-powered dispensing device
US5993412A (en) 1997-05-19 1999-11-30 Bioject, Inc. Injection apparatus
IT1298087B1 (it) 1998-01-08 1999-12-20 Fiderm S R L Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni
WO2000009115A1 (en) * 1998-08-14 2000-02-24 Smithkline Beecham Corporation Grp receptor ligands
BR9917079A (pt) 1998-12-18 2001-10-30 Du Pont Pharm Co Compostos antagonistas de receptor devitronectina, kit, composição metalofarmacêuticade diagnóstico ou terapêutica, composição deagente de contraste para ultra-som, composiçãoradiofarmacêutica terapêutica, composiçãofarmacêutica de diagnóstico, método detratamento da artrite reumatóide, do cancêr e darestenose em um paciente, método de formação deimagem da angiogênese terapêutica, do câncer, denovos vasos sanguìneos, da arteriosclerose, darestenose, da isquemia e da lesão por reperfusãodo miocárdio em um paciente
GB0019357D0 (en) * 2000-08-07 2000-09-27 Melacure Therapeutics Ab Novel phenyl guanidines
DE10114561A1 (de) 2001-03-24 2002-09-26 Wella Ag Verwendung von Mitteln enthaltend Kreatin, Kreatin und/oder deren Derivaten zur Verstärkung und Strukturverbesserung von keratinischen Fasern
US7344702B2 (en) 2004-02-13 2008-03-18 Bristol-Myers Squibb Pharma Company Contrast agents for myocardial perfusion imaging
AU2003298582A1 (en) 2002-09-17 2004-05-13 Isis Pharmaceuticals, Inc. Therapeutic guanidines
CA2549141C (en) 2003-12-01 2012-10-23 Medi-Physics, Inc. Novel differential imaging method
US7632485B2 (en) 2004-02-24 2009-12-15 Massachusetts General Hospital Catalytic radiofluorination
US20060100225A1 (en) 2004-03-23 2006-05-11 Xi Chen Heteroaryl guanidines; inhibitors of viral replication
US7485283B2 (en) 2004-04-28 2009-02-03 Lantheus Medical Imaging Contrast agents for myocardial perfusion imaging
EP1749815B1 (en) 2004-05-28 2017-06-21 Hamamatsu Photonics K.K. Radioactive tyrosine derivative, method for producing same, labeling agent for positron imaging and medical agent for assessing grade of malignancy of tumor respectively composed of radioactive tyrosine derivative, and method for detecting tumor
ATE493152T1 (de) 2004-09-23 2011-01-15 Guerbet Sa Liposomale kontrastmittel für die cest-bildgebung
US7534418B2 (en) * 2004-12-10 2009-05-19 The Regents Of The University Of Michigan Imaging agents
GB0512770D0 (en) 2005-06-23 2005-07-27 Hammersmith Imanet Ltd Imaging compounds
US7824659B2 (en) 2005-08-10 2010-11-02 Lantheus Medical Imaging, Inc. Methods of making radiolabeled tracers and precursors thereof
JP2007112725A (ja) 2005-10-18 2007-05-10 Inst Nuclear Energy Research Rocaec 無支持体の18Fで標識したアミノ酸O−(2−[18F]fluoroethyl)−L−Tyrosineの製造方法。
WO2008118122A2 (en) 2006-05-08 2008-10-02 Molecular Neuroimaging, Llc Compounds and amyloid probes thereof for therapeutic and imaging uses
MX2009000334A (es) 2006-08-25 2009-01-28 Boehringer Ingelheim Int Nuevos derivados de piridona con actividad antagonista de mch y medicamentos que comprenden estos compuestos.
US7823227B2 (en) * 2006-10-10 2010-11-02 Joseph Damianoe Bathroom odor removal apparatus and system
GB0625523D0 (en) * 2006-12-21 2007-01-31 Ge Healthcare Ltd In vivo imaging agents
EP2474523B1 (en) * 2006-12-26 2020-04-08 Lantheus Medical Imaging, Inc. Ligands for imaging cardiac innervation
US7887784B2 (en) 2007-03-21 2011-02-15 University Of Montana 1-[(2′-substituted)-piperazin-1′ -yl]-isoquinolines as norepinephrine transporter inhibitor therapeutics and positron emission tomography imaging agents
US7807394B2 (en) 2007-04-05 2010-10-05 Siemens Medical Solutions Usa, Inc. Nitro-imidazole hypoxia imaging agents
KR101068835B1 (ko) 2007-10-26 2011-09-30 한국과학기술연구원 베타-아밀로이드 집적체 및 피브릴에 우수한 결합 친화도를가지는 이소인돌론 화합물 및 이의 제조 방법
WO2009103478A1 (en) 2008-02-19 2009-08-27 Boehringer Ingelheim International Gmbh Pyridone and pyridazinone derivatives as mch antagonists
WO2010011367A2 (en) 2008-02-22 2010-01-28 Illinois Institute Of Technology Bimodal ligands with macrocyclic and acyclic binding moieties, complexes and compositions thereof, and methods of using
ES2767973T3 (es) 2008-02-29 2020-06-19 Lantheus Medical Imaging Inc Agentes de contraste para aplicaciones que comprenden formación de imágenes de perfusión
CN101585816B (zh) 2008-05-20 2011-04-20 中国科学院上海应用物理研究所 一种苯磺酰胺类羟基衍生物及其中间体及制备方法和应用
WO2010015340A1 (en) 2008-08-06 2010-02-11 Bayer Schering Pharma Aktiengesellschaft Daa-pyridine as peripheral benzodiazepine receptor ligand for diagnostic imaging and pharmaceutical treatment
EP2406233B1 (en) 2009-03-09 2013-11-13 Bristol-Myers Squibb Company Aza pyridone analogs useful as melanin concentrating hormone receptor-1 antagonists
GB0906274D0 (en) 2009-04-09 2009-05-20 Ge Healthcare Ltd Imaging the central nervous system
JP5662416B2 (ja) 2009-04-15 2015-01-28 ランセウス メディカル イメージング, インコーポレイテッド アスコルビン酸による放射性医薬組成物の安定化
CN101555232B (zh) 2009-05-21 2011-01-05 北京师范大学 氟-18标记哒嗪酮类化合物及制备方法和应用
EP2451776B1 (en) 2009-07-08 2019-09-18 Lantheus Medical Imaging, Inc. N-alkoxyamide conjugates as imaging agents
BR112012019789A2 (pt) 2010-02-08 2016-08-09 Lantheus Medical Imaging Inc métodos e aparelhos para sintetizar agentes de imagiologia, e seus intermediários
WO2011143360A2 (en) * 2010-05-11 2011-11-17 Lantheus Medical Imaging, Inc. Compositions, methods and systems for the synthesis and use of imaging agents
AU2013203000B9 (en) 2012-08-10 2017-02-02 Lantheus Medical Imaging, Inc. Compositions, methods, and systems for the synthesis and use of imaging agents
JP2017131851A (ja) * 2016-01-29 2017-08-03 日本特殊陶業株式会社 マイクロ波加熱用触媒材料、マイクロ波加熱用触媒体、及び、その製造方法

Similar Documents

Publication Publication Date Title
JP2014531434A5 (cg-RX-API-DMAC7.html)
JP2017537940A5 (cg-RX-API-DMAC7.html)
JP2008195730A5 (cg-RX-API-DMAC7.html)
JP2019094345A5 (cg-RX-API-DMAC7.html)
JP2012533630A5 (cg-RX-API-DMAC7.html)
JP2019034943A5 (cg-RX-API-DMAC7.html)
JP2017526726A5 (cg-RX-API-DMAC7.html)
JP2015522650A5 (cg-RX-API-DMAC7.html)
JP2013538230A5 (cg-RX-API-DMAC7.html)
JP2017511815A5 (cg-RX-API-DMAC7.html)
JP2004516314A5 (cg-RX-API-DMAC7.html)
JP2013518107A5 (cg-RX-API-DMAC7.html)
JP2016516043A5 (cg-RX-API-DMAC7.html)
JP2009526034A5 (cg-RX-API-DMAC7.html)
JP2017526675A5 (cg-RX-API-DMAC7.html)
JP2019532928A5 (cg-RX-API-DMAC7.html)
JP2018511647A5 (cg-RX-API-DMAC7.html)
JP2014510774A5 (cg-RX-API-DMAC7.html)
JP2010501584A5 (cg-RX-API-DMAC7.html)
JP2013508279A5 (cg-RX-API-DMAC7.html)
JP2015508092A5 (cg-RX-API-DMAC7.html)
JP2012519691A5 (cg-RX-API-DMAC7.html)
JP2019507111A5 (cg-RX-API-DMAC7.html)
JP2015508068A5 (cg-RX-API-DMAC7.html)
JP2015535847A5 (cg-RX-API-DMAC7.html)