JP2014531252A - 造影剤のパッケージング - Google Patents
造影剤のパッケージング Download PDFInfo
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- JP2014531252A JP2014531252A JP2014531216A JP2014531216A JP2014531252A JP 2014531252 A JP2014531252 A JP 2014531252A JP 2014531216 A JP2014531216 A JP 2014531216A JP 2014531216 A JP2014531216 A JP 2014531216A JP 2014531252 A JP2014531252 A JP 2014531252A
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- 229960000780 iomeprol Drugs 0.000 description 1
- NJKDOADNQSYQEV-UHFFFAOYSA-N iomeprol Chemical compound OCC(=O)N(C)C1=C(I)C(C(=O)NCC(O)CO)=C(I)C(C(=O)NCC(O)CO)=C1I NJKDOADNQSYQEV-UHFFFAOYSA-N 0.000 description 1
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- IUNJANQVIJDFTQ-UHFFFAOYSA-N iopentol Chemical compound COCC(O)CN(C(C)=O)C1=C(I)C(C(=O)NCC(O)CO)=C(I)C(C(=O)NCC(O)CO)=C1I IUNJANQVIJDFTQ-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1412—Containers with closing means, e.g. caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/06—Ampoules or carpules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/007—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests for contrast media
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
- B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B7/00—Closing containers or receptacles after filling
- B65B7/16—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D51/00—Closures not otherwise provided for
- B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J2205/00—General identification or selection means
- A61J2205/20—Colour codes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]
- Y10T428/1352—Polymer or resin containing [i.e., natural or synthetic]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]
- Y10T428/1352—Polymer or resin containing [i.e., natural or synthetic]
- Y10T428/1386—Natural or synthetic rubber or rubber-like compound containing
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Packging For Living Organisms, Food Or Medicinal Products That Are Sensitive To Environmental Conditiond (AREA)
- Packages (AREA)
- Closures For Containers (AREA)
Abstract
Description
式(I)
式中、
Xは、1又は2つのCH2基が酸素原子、硫黄原子又はNR4基で適宜置き換えられたC3〜C8直鎖又は枝分れアルキレン基を表し、アルキレン基は適宜6個以下の−OR4基で置換されており、
R4は水素原子或いはC1〜C4直鎖又は枝分れアルキル基を表し、
R6は水素原子又はホルミル基のようなアシル官能基を表し、
各Rは独立に同一又は異なるものであって、さらに2つのR5基で置換されたトリヨウ素化フェニル基(好ましくは2,4,6−トリヨウ素化フェニル基)を表し、ここで各R5は同一又は異なるものであって、式(I)の化合物の少なくとも1つのR5基が親水性基であることを条件として水素原子又は非イオン性親水性基を表す。好ましい基及び化合物については国際公開第2010/079201号及び国際公開第2009/008734号に記載されており、その開示内容は援用によって本明細書の内容の一部をなす。
実施例
実施例1:異なる温度で異なる密閉手段を用いたイオフォルミノール溶液の安定性試験
実験的研究を設計し、第1のパッケージング材料がイオフォルミノール320mgl/mlの物理的安定性にどのように影響を与えるかを調査した。
PP: ポリプロピレン
COP: シクロオレフィンポリマー
COC: 環状オレフィンコポリマー
Claims (13)
- カーボンブラックを含む密閉手段で密閉した容器を含み、容器にX線造影剤の過飽和溶液が充填されている、パッケージ。
- 過飽和溶液が造影剤イオフォルミノールを含む、請求項1記載のパッケージ。
- 容器が、瓶、バイアル及びシリンジからなる群から選択される、請求項1又は請求項2記載のパッケージ。
- 密閉手段が、ストッパー、プランジャーストッパー、栓、シール、キャップ、蓋及びコルクからなる群から選択される、請求項1乃至請求項3のいずれか1項記載のパッケージ。
- 密閉手段が、カーボンブラックによって黒色に着色されている、請求項1乃至請求項4のいずれか1項記載のパッケージ。
- 密閉手段の材料が21%以下のカーボンブラックを含む、請求項1乃至請求項5のいずれか1項記載のパッケージ。
- 密閉手段の材料が0.1〜5.0%のカーボンブラックを含む、請求項1乃至請求項6のいずれか1項記載のパッケージ。
- 密閉手段がハロブチル系ゴムを含む、請求項1乃至請求項7のいずれか1項記載のパッケージ。
- 密閉手段がスチレン系ゴムを含む、請求項6記載のパッケージ。
- 密閉手段がストッパーであり、パッケージが、ストッパーを覆うキャップをさらに含む、請求項1乃至請求項9のいずれか1項記載のパッケージ。
- X線造影剤の過飽和溶液の安定性を向上させる方法であって、溶液を容器に充填し、カーボンブラックを含む密閉手段で容器を密閉することを含む方法。
- 請求項1乃至請求項10のいずれか1項記載のパッケージを使用する、請求項11記載の方法。
- 殺菌段階をさらに含む、請求項11又は請求項12記載の方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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EP11182144.3 | 2011-09-21 | ||
EP11182144 | 2011-09-21 | ||
PCT/EP2012/068475 WO2013041593A1 (en) | 2011-09-21 | 2012-09-20 | Packaging of contrast media |
Related Child Applications (1)
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JP2019004257A Division JP2019072537A (ja) | 2011-09-21 | 2019-01-15 | 造影剤のパッケージング |
Publications (1)
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JP2014531252A true JP2014531252A (ja) | 2014-11-27 |
Family
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Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014531216A Withdrawn JP2014531252A (ja) | 2011-09-21 | 2012-09-20 | 造影剤のパッケージング |
JP2019004257A Pending JP2019072537A (ja) | 2011-09-21 | 2019-01-15 | 造影剤のパッケージング |
Family Applications After (1)
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JP2019004257A Pending JP2019072537A (ja) | 2011-09-21 | 2019-01-15 | 造影剤のパッケージング |
Country Status (8)
Country | Link |
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US (1) | US20140319005A1 (ja) |
EP (1) | EP2758319B1 (ja) |
JP (2) | JP2014531252A (ja) |
CN (1) | CN103998349B (ja) |
AU (1) | AU2012311584B2 (ja) |
ES (1) | ES2584659T3 (ja) |
PL (1) | PL2758319T3 (ja) |
WO (1) | WO2013041593A1 (ja) |
Families Citing this family (1)
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GB201721463D0 (en) * | 2017-12-20 | 2018-01-31 | Ge Healthcare As | Tailored dose of contrast agent |
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JP2010533172A (ja) * | 2007-07-12 | 2010-10-21 | ジーイー・ヘルスケア・アクスイェ・セルスカプ | 造影剤 |
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2012
- 2012-09-20 CN CN201280056983.XA patent/CN103998349B/zh not_active Expired - Fee Related
- 2012-09-20 JP JP2014531216A patent/JP2014531252A/ja not_active Withdrawn
- 2012-09-20 ES ES12759479.4T patent/ES2584659T3/es active Active
- 2012-09-20 PL PL12759479.4T patent/PL2758319T3/pl unknown
- 2012-09-20 US US14/346,373 patent/US20140319005A1/en not_active Abandoned
- 2012-09-20 EP EP12759479.4A patent/EP2758319B1/en not_active Not-in-force
- 2012-09-20 AU AU2012311584A patent/AU2012311584B2/en not_active Ceased
- 2012-09-20 WO PCT/EP2012/068475 patent/WO2013041593A1/en active Application Filing
-
2019
- 2019-01-15 JP JP2019004257A patent/JP2019072537A/ja active Pending
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JPS5982355A (ja) * | 1982-10-01 | 1984-05-12 | ニユエガ−ド・アンド・コンパニ−・アクシエ/セルカペト | X線造影剤 |
JPH01178261A (ja) * | 1988-01-06 | 1989-07-14 | Daikyo Rubber Seiko:Kk | 医薬品・医療器具用ゴム製品 |
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Also Published As
Publication number | Publication date |
---|---|
EP2758319A1 (en) | 2014-07-30 |
ES2584659T3 (es) | 2016-09-28 |
CN103998349A (zh) | 2014-08-20 |
WO2013041593A1 (en) | 2013-03-28 |
AU2012311584A1 (en) | 2014-04-10 |
JP2019072537A (ja) | 2019-05-16 |
US20140319005A1 (en) | 2014-10-30 |
CN103998349B (zh) | 2020-01-14 |
AU2012311584B2 (en) | 2017-04-20 |
PL2758319T3 (pl) | 2016-11-30 |
EP2758319B1 (en) | 2016-06-08 |
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