JP2014531213A5 - - Google Patents

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JP2014531213A5
JP2014531213A5 JP2014533357A JP2014533357A JP2014531213A5 JP 2014531213 A5 JP2014531213 A5 JP 2014531213A5 JP 2014533357 A JP2014533357 A JP 2014533357A JP 2014533357 A JP2014533357 A JP 2014533357A JP 2014531213 A5 JP2014531213 A5 JP 2014531213A5
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JP
Japan
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cpg site
absence
methylation
kit
group
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JP2014533357A
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JP2014531213A (ja
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Priority claimed from PCT/US2012/057777 external-priority patent/WO2013055530A1/en
Publication of JP2014531213A publication Critical patent/JP2014531213A/ja
Publication of JP2014531213A5 publication Critical patent/JP2014531213A5/ja
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JP2014533357A 2011-09-30 2012-09-28 上皮又は間葉の表現型の診断用メチル化マーカー、及び腫瘍又は腫瘍細胞におけるｅｇｆｒキナーゼ阻害薬に対する応答 Pending JP2014531213A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161542141P 2011-09-30 2011-09-30
US61/542,141 2011-09-30
PCT/US2012/057777 WO2013055530A1 (en) 2011-09-30 2012-09-28 Diagnostic methylation markers of epithelial or mesenchymal phenotype and response to egfr kinase inhibitor in tumours or tumour cells

Publications (2)

Publication Number Publication Date
JP2014531213A JP2014531213A (ja) 2014-11-27
JP2014531213A5 true JP2014531213A5 (https=) 2015-07-23

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JP2014533357A Pending JP2014531213A (ja) 2011-09-30 2012-09-28 上皮又は間葉の表現型の診断用メチル化マーカー、及び腫瘍又は腫瘍細胞におけるｅｇｆｒキナーゼ阻害薬に対する応答

Country Status (14)

Country Link
US (1) US20130084287A1 (https=)
EP (1) EP2761025A1 (https=)
JP (1) JP2014531213A (https=)
KR (1) KR20140066783A (https=)
CN (1) CN104066851A (https=)
AU (1) AU2012321248A1 (https=)
BR (1) BR112014007569A2 (https=)
CA (1) CA2849120A1 (https=)
IL (1) IL231590A0 (https=)
MX (1) MX2014003698A (https=)
RU (1) RU2014110228A (https=)
SG (1) SG11201400996SA (https=)
WO (1) WO2013055530A1 (https=)
ZA (1) ZA201401968B (https=)

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UY35814A (es) * 2013-11-04 2015-05-29 Dow Agrosciences Llc ?lugares óptimos para la soja?.
JP6779858B2 (ja) * 2014-07-29 2020-11-04 ウェルマーカー バイオ カンパニー リミテッド Ｅｇｆｒ−標的製剤に対する感受性予測用の新規なバイオマーカー及びその用途
JP6709541B2 (ja) * 2014-10-17 2020-06-17 国立大学法人東北大学 大腸癌に対する薬物療法の感受性を予測する方法
ES2879964T3 (es) 2014-12-12 2021-11-23 Exact Sciences Dev Co Llc Composiciones y métodos para realizar ensayos de detección de metilación
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JP7113842B2 (ja) * 2017-03-29 2022-08-05 クラウン バイオサイエンス，インコーポレイテッド（タイツァン） 胃がんのセツキシマブ感受性を決定するためのシステムおよび方法
CN107144695B (zh) * 2017-04-19 2019-02-26 南昌大学 Arl13b蛋白在癌症诊断中的应用
CN110662844A (zh) 2017-05-22 2020-01-07 内盖夫生物技术国家研究所有限公司 用于肺癌的诊断的生物标志物
CN118086498A (zh) 2018-01-18 2024-05-28 纽克莱克斯有限公司 用于诊断肺癌的方法
WO2019238792A1 (en) * 2018-06-15 2019-12-19 Unilever Plc Epigenetic method to assess sun exposure
BR112021009795A2 (pt) * 2018-11-27 2021-08-17 Exact Sciences Development Company, Llc métodos de caracterização e para caracterizar uma amostra, kit e composição
CN111521810B (zh) * 2019-02-02 2024-06-21 中国科学院上海药物研究所 癌症患者根据脾酪氨酸激酶进行分层
IL265451B (en) 2019-03-18 2020-01-30 Frumkin Dan Methods and systems for the detection of methylation changes in DNA samples
CN110283910B (zh) * 2019-06-21 2021-04-20 浙江大学 目标基因dna甲基化作为分子标志物在制备判别结直肠组织癌变进展试剂盒中的应用
CN111304305B (zh) * 2020-03-30 2023-05-30 陕西科技大学 一种用于检测egfr基因甲基化的试剂盒及方法
CN111676286B (zh) * 2020-05-29 2023-04-14 武汉爱基百客生物科技有限公司 肺癌血浆游离dna甲基化检测用的多重pcr引物系统、检测方法及应用
CN114354927B (zh) * 2021-03-18 2025-04-22 中国人民解放军陆军特色医学中心 唾液酸转移酶st3gal4作为egfr-tki耐药标志物的新应用
CN115772565B (zh) * 2021-09-08 2023-09-05 广州市基准医疗有限责任公司 用于辅助检测肺癌体细胞egfr基因突变的甲基化位点及其应用
CN114525281B (zh) * 2022-03-14 2024-03-12 右江民族医学院 Esrp1启动子报告基因转录活性可视化及在去甲基化抗癌药物筛选中的应用
CN115651984B (zh) * 2022-10-20 2023-04-14 山东大学 一种生物标志物在评价肿瘤紫杉类化疗耐药性的应用

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