|
US3126375A
(en)
|
|
1964-03-24 |
|
Chioacyl |
|
US2789118A
(en)
|
1956-03-30 |
1957-04-16 |
American Cyanamid Co |
16-alpha oxy-belta1, 4-pregnadienes
|
|
US2990401A
(en)
|
1958-06-18 |
1961-06-27 |
American Cyanamid Co |
11-substituted 16alpha, 17alpha-substituted methylenedioxy steroids
|
|
US3048581A
(en)
|
1960-04-25 |
1962-08-07 |
Olin Mathieson |
Acetals and ketals of 16, 17-dihydroxy steroids
|
|
US3749712A
(en)
|
1970-09-25 |
1973-07-31 |
Sigma Tau Ind Farmaceuti |
Triamcinolone acetonide esters and process for their preparation
|
|
BE794063A
(fr)
|
1972-01-17 |
1973-07-16 |
Henkel & Cie Gmbh |
Anti-inflammatoires pour compositions cosmetiques
|
|
SE378109B
(https=)
|
1972-05-19 |
1975-08-18 |
Bofors Ab |
|
|
US3996359A
(en)
|
1972-05-19 |
1976-12-07 |
Ab Bofors |
Novel stereoisomeric component A of stereoisomeric mixtures of 2'-unsymmetrical 16,17-methylenedioxy steroid 21-acylates, compositions thereof, and method of treating therewith
|
|
SE378110B
(https=)
|
1972-05-19 |
1975-08-18 |
Bofors Ab |
|
|
US3775656A
(en)
|
1972-05-22 |
1973-11-27 |
Aviat Inc |
Platform stabilization system
|
|
CH581818A5
(https=)
|
1973-02-27 |
1976-11-15 |
Cierva Juan J De |
|
|
US4327725A
(en)
|
1980-11-25 |
1982-05-04 |
Alza Corporation |
Osmotic device with hydrogel driving member
|
|
EP0084236A3
(en)
|
1981-12-22 |
1983-08-03 |
Fbc Limited |
Fungicidal heterocyclic compounds and compositions containing them
|
|
US4498038A
(en)
|
1983-02-15 |
1985-02-05 |
Malueg Richard M |
Stabilization system for soft-mounted platform
|
|
US4624848A
(en)
|
1984-05-10 |
1986-11-25 |
Ciba-Geigy Corporation |
Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use
|
|
GB8518301D0
(en)
|
1985-07-19 |
1985-08-29 |
Fujisawa Pharmaceutical Co |
Hydrodynamically explosive systems
|
|
US5011692A
(en)
|
1985-12-28 |
1991-04-30 |
Sumitomo Pharmaceuticals Company, Limited |
Sustained pulsewise release pharmaceutical preparation
|
|
US4968509A
(en)
|
1987-07-27 |
1990-11-06 |
Mcneilab, Inc. |
Oral sustained release acetaminophen formulation and process
|
|
DE3889545T2
(de)
|
1987-10-20 |
1994-10-13 |
Otsuka Pharma Co Ltd |
Phenylcarbonsäure-abkömmlinge.
|
|
US5033252A
(en)
|
1987-12-23 |
1991-07-23 |
Entravision, Inc. |
Method of packaging and sterilizing a pharmaceutical product
|
|
US5052558A
(en)
|
1987-12-23 |
1991-10-01 |
Entravision, Inc. |
Packaged pharmaceutical product
|
|
US5612059A
(en)
|
1988-08-30 |
1997-03-18 |
Pfizer Inc. |
Use of asymmetric membranes in delivery devices
|
|
IL92966A
(en)
|
1989-01-12 |
1995-07-31 |
Pfizer |
Dispensing devices powered by hydrogel
|
|
JPH03215470A
(ja)
|
1990-01-22 |
1991-09-20 |
Suntory Ltd |
プロピオン酸アミド誘導体，その製造法及びそれを有効成分として含有する除草剤
|
|
US5017381A
(en)
|
1990-05-02 |
1991-05-21 |
Alza Corporation |
Multi-unit pulsatile delivery system
|
|
WO1992018106A1
(fr)
|
1991-04-16 |
1992-10-29 |
Nippon Shinyaku Co., Ltd. |
Procede de production d'une dispersion solide
|
|
DE4124345A1
(de)
|
1991-07-23 |
1993-01-28 |
Gruenenthal Gmbh |
Substituierte 3,4-dihydronaphthaline, diese verbindungen enthaltende arzneimittel und verfahren zur herstellung dieser verbindungen und arzneimittel
|
|
HU227530B1
(en)
|
1991-11-22 |
2011-07-28 |
Warner Chilcott Company |
Delayed-release compositions containing risedronate and process for their production
|
|
US5229135A
(en)
|
1991-11-22 |
1993-07-20 |
Prographarm Laboratories |
Sustained release diltiazem formulation
|
|
US5461140A
(en)
|
1992-04-30 |
1995-10-24 |
Pharmaceutical Delivery Systems |
Bioerodible polymers for solid controlled release pharmaceutical compositions
|
|
US5260068A
(en)
|
1992-05-04 |
1993-11-09 |
Anda Sr Pharmaceuticals Inc. |
Multiparticulate pulsatile drug delivery system
|
|
US5323907A
(en)
|
1992-06-23 |
1994-06-28 |
Multi-Comp, Inc. |
Child resistant package assembly for dispensing pharmaceutical medications
|
|
JP2616252B2
(ja)
|
1992-10-16 |
1997-06-04 |
日本新薬株式会社 |
ワックスマトリックスの製法
|
|
US5260069A
(en)
|
1992-11-27 |
1993-11-09 |
Anda Sr Pharmaceuticals Inc. |
Pulsatile particles drug delivery system
|
|
US5686105A
(en)
|
1993-10-19 |
1997-11-11 |
The Procter & Gamble Company |
Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery
|
|
DE4327365A1
(de)
|
1993-08-14 |
1995-02-16 |
Boehringer Mannheim Gmbh |
Verwendung von Phenolen und Phenolderivaten als Arzneimittel mit fibrinogensenkender Wirkung
|
|
US5448938A
(en)
|
1993-10-18 |
1995-09-12 |
Guardian Technologies International, Inc. |
Removable ballistic resistant armor seat cover and floor mat
|
|
US5567441A
(en)
|
1995-03-24 |
1996-10-22 |
Andrx Pharmaceuticals Inc. |
Diltiazem controlled release formulation
|
|
JPH11505258A
(ja)
|
1995-05-17 |
1999-05-18 |
セダーシナイ メディカル センター |
小腸における消化および吸収を改善させる脂肪酸を含む組成物
|
|
US5798119A
(en)
|
1995-06-13 |
1998-08-25 |
S. C. Johnson & Son, Inc. |
Osmotic-delivery devices having vapor-permeable coatings
|
|
US5837284A
(en)
|
1995-12-04 |
1998-11-17 |
Mehta; Atul M. |
Delivery of multiple doses of medications
|
|
US5958957A
(en)
|
1996-04-19 |
1999-09-28 |
Novo Nordisk A/S |
Modulators of molecules with phosphotyrosine recognition units
|
|
US5840329A
(en)
|
1997-05-15 |
1998-11-24 |
Bioadvances Llc |
Pulsatile drug delivery system
|
|
US6211197B1
(en)
|
1998-10-07 |
2001-04-03 |
Merck Frosst Canada & Co. |
Prostaglandin receptor ligands
|
|
US6395300B1
(en)
|
1999-05-27 |
2002-05-28 |
Acusphere, Inc. |
Porous drug matrices and methods of manufacture thereof
|
|
US6611662B1
(en)
|
1999-05-28 |
2003-08-26 |
David E. Grober |
Autonomous, self leveling, self correcting stabilized platform
|
|
US6718130B2
(en)
|
1999-05-28 |
2004-04-06 |
David E. Grober |
Stabilized camera and marker buoy for media coverage of aquatic events
|
|
CA2379608A1
(en)
|
1999-08-10 |
2001-02-15 |
Pangene Corporation |
Cancer treatments and diagnostics utilizing rad51 related molecules and methods
|
|
AU6936500A
(en)
|
1999-08-24 |
2001-03-19 |
Regents Of The University Of California, The |
Non-quinoline inhibitors of malaria parasites
|
|
JP2003509428A
(ja)
|
1999-09-17 |
2003-03-11 |
アボツト・ゲー・エム・ベー・ハー・ウント・コンパニー・カーゲー |
治療薬としてのピラゾロピリミジン
|
|
US6921763B2
(en)
|
1999-09-17 |
2005-07-26 |
Abbott Laboratories |
Pyrazolopyrimidines as therapeutic agents
|
|
EP1748046A3
(en)
|
1999-11-23 |
2007-08-22 |
Methylgene, Inc. |
Inhibitors of histone deacetylase
|
|
BR0113626A
(pt)
|
2000-08-30 |
2003-06-17 |
Pfizer Prod Inc |
Formulações de liberação sustentada para secretores de hormÈnio do crescimento
|
|
GB0023983D0
(en)
|
2000-09-29 |
2000-11-15 |
Prolifix Ltd |
Therapeutic compounds
|
|
JP4975941B2
(ja)
|
2000-09-29 |
2012-07-11 |
トポターゲット ユーケー リミテッド |
（ｅ）−ｎ−ヒドロキシ−３−（３−スルファモイル−フェニル）アクリルアミド化合物及びその治療用途
|
|
AU9598601A
(en)
|
2000-10-20 |
2002-04-29 |
Eisai Co Ltd |
Nitrogenous aromatic ring compounds
|
|
EP1358353B1
(en)
|
2000-12-28 |
2007-06-20 |
Epidauros Biotechnologie AG |
Identification of genetic determinants of polymorphic cyp3a5 expression
|
|
MXPA01013172A
(es)
|
2001-02-14 |
2002-08-21 |
Warner Lambert Co |
Inhibidores sulfonamida de metaloproteinasa de matriz.
|
|
US6465014B1
(en)
|
2001-03-21 |
2002-10-15 |
Isp Investments Inc. |
pH-dependent sustained release, drug-delivery composition
|
|
MXPA03008560A
(es)
|
2001-03-22 |
2004-06-30 |
Abbot Gmbh & Co Kg |
Pirazolopirimidinas como agentes terapeuticos.
|
|
ATE432068T1
(de)
|
2001-06-28 |
2009-06-15 |
Ucb Farchim Sa |
Cetirizin und pseudoephedrin enthaltende tablette
|
|
US7247426B2
(en)
|
2001-08-02 |
2007-07-24 |
Agilent Technologies, Inc. |
Classifying cancers
|
|
ITMI20011733A1
(it)
|
2001-08-07 |
2003-02-07 |
Italfarmaco Spa |
Derivati dell'acido idrossamico inibitori degli enzimi istone deacetilasi, quali nuovi farmaci antiinfiammatori inibenti la sintesi di citoc
|
|
JP4238728B2
(ja)
|
2001-08-21 |
2009-03-18 |
アステラス製薬株式会社 |
ヒストンデアセチラーゼ阻害剤の医薬用途ならびにその抗腫瘍効果の評価方法
|
|
US20040142325A1
(en)
|
2001-09-14 |
2004-07-22 |
Liat Mintz |
Methods and systems for annotating biomolecular sequences
|
|
US20030166026A1
(en)
|
2002-01-09 |
2003-09-04 |
Lynx Therapeutics, Inc. |
Identification of specific biomarkers for breast cancer cells
|
|
US20060078879A1
(en)
|
2002-02-04 |
2006-04-13 |
Epidauros Biotechnologie Ag |
Polymorphisms in the human gene for tpmt and their use in diagnostic and therapeutic applications
|
|
JPWO2003070691A1
(ja)
|
2002-02-21 |
2005-06-09 |
財団法人大阪産業振興機構 |
Ｎ−ヒドロキシカルボキサミド誘導体
|
|
US20040132825A1
(en)
|
2002-03-04 |
2004-07-08 |
Bacopoulos Nicholas G. |
Methods of treating cancer with HDAC inhibitors
|
|
WO2004013130A1
(en)
|
2002-08-02 |
2004-02-12 |
Argenta Discovery Limited |
Substituted thienyl-hydroxamic acids as histone deacetylase inhibitors
|
|
EP1400806A1
(en)
|
2002-09-18 |
2004-03-24 |
G2M Cancer Drugs AG |
The use of molecular markers for the preclinical and clinical profiling of inhibitors of enzymes having histone deacetylase activity
|
|
US6769347B1
(en)
|
2002-11-26 |
2004-08-03 |
Recon/Optical, Inc. |
Dual elevation weapon station and method of use
|
|
EP1595952A4
(en)
|
2003-02-19 |
2008-05-21 |
Astellas Pharma Inc |
METHOD FOR EVALUATING THE ANTITUMOR EFFECT OF A HISTONE DEACETYLASE INHIBITOR
|
|
GB0303910D0
(en)
|
2003-02-20 |
2003-03-26 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US7381825B2
(en)
|
2003-03-17 |
2008-06-03 |
Takeda San Diego, Inc. |
Histone deacetylase inhibitors
|
|
BRPI0409227C1
(pt)
|
2003-04-07 |
2021-05-25 |
Axys Pharm Inc |
composto, composição farmacêutica, uso de um composto e processo para a preparação de um composto de fórmula (i)
|
|
CN1768031A
(zh)
*
|
2003-04-07 |
2006-05-03 |
Axys药物公司 |
作为治疗剂的异羟肟酸酯
|
|
PE20050206A1
(es)
|
2003-05-26 |
2005-03-26 |
Schering Ag |
Composicion farmaceutica que contiene un inhibidor de histona deacetilasa
|
|
ES2425083T3
(es)
|
2003-09-25 |
2013-10-11 |
Astellas Pharma Inc. |
Agente antitumoral que comprende FK228 como inhibidor de histona desacetilasa y doxorrubicina como inhibidor de topoisomerasa II
|
|
WO2005043161A2
(en)
|
2003-11-04 |
2005-05-12 |
Roche Diagnostics Gmbh |
Method for distinguishing leukemia subtypes
|
|
CA2549324A1
(en)
|
2003-12-12 |
2005-06-30 |
Bayer Pharmaceuticals Corporation |
Gene expression profiles and methods of use
|
|
JP2007527247A
(ja)
|
2004-03-05 |
2007-09-27 |
ロゼッタ インファーマティクス エルエルシー |
臨床的基準および情報提供性遺伝子セットの組合せを使用する乳癌患者の分類
|
|
GB2427405A
(en)
|
2004-04-07 |
2006-12-27 |
Pharmacyclics Inc |
Novel hydroxamates as therapeutic agents
|
|
DK1591109T3
(da)
|
2004-04-30 |
2008-10-06 |
Topotarget Germany Ag |
Formulering, der omfatter histondeacetylaseinhibitorer, der udviser tofaset frigivelse
|
|
EP1761281A1
(en)
|
2004-06-04 |
2007-03-14 |
Pfizer Products Incorporated |
Method for treating abnormal cell growth
|
|
WO2006015312A2
(en)
|
2004-07-30 |
2006-02-09 |
Rosetta Inpharmatics Llc |
Prognosis of breast cancer patients
|
|
US20080248506A1
(en)
|
2004-10-07 |
2008-10-09 |
Pharmacyclics, Inc. |
Method of Monitoring Anti-Tumor Activity of an Hdac Inhibitor
|
|
MX2007005361A
(es)
|
2004-11-05 |
2008-01-11 |
Cephalon Inc |
Tratamientos para cancer.
|
|
US8436190B2
(en)
*
|
2005-01-14 |
2013-05-07 |
Cephalon, Inc. |
Bendamustine pharmaceutical compositions
|
|
WO2006101454A1
(en)
|
2005-03-21 |
2006-09-28 |
S*Bio Pte Ltd |
Benzothiophene derivatives: preparation and pharmaceutical applications
|
|
US8338416B2
(en)
|
2006-03-16 |
2012-12-25 |
Pharmacylics, Inc. |
Indole derivatives as inhibitors of histone deacetylase
|
|
EP2066327B1
(en)
|
2006-09-15 |
2012-11-14 |
Janssen Pharmaceutica NV |
Histone deacetylase inhibitors with combined activity on class-i and class-iib histone deacetylases in combination with proteasome inhibitors
|
|
US9408816B2
(en)
|
2006-12-26 |
2016-08-09 |
Pharmacyclics Llc |
Method of using histone deacetylase inhibitors and monitoring biomarkers in combination therapy
|
|
AU2008210421B2
(en)
|
2007-01-30 |
2014-03-13 |
Pharmacyclics Llc |
Methods for determining cancer resistance to histone deacetylase inhibitors
|
|
EP2060565A1
(en)
*
|
2007-11-16 |
2009-05-20 |
4Sc Ag |
Novel bifunctional compounds which inhibit protein kinases and histone deacetylases
|
|
EP2110377A1
(en)
*
|
2008-04-15 |
2009-10-21 |
DAC S.r.l. |
Spirocyclic derivatives as histone deacetylase inhibitors
|
|
US8603521B2
(en)
|
2009-04-17 |
2013-12-10 |
Pharmacyclics, Inc. |
Formulations of histone deacetylase inhibitor and uses thereof
|
|
UY34295A
(es)
|
2011-09-08 |
2013-04-30 |
Servier Lab |
Nuevo esquema de administración de la n-hidroxi -4- {2-[3- (n,ndimetilaminometil)benzofuran -2- ilcarbonilamino]etoxi}benzamida
|
|
JP6330118B2
(ja)
|
2011-09-13 |
2018-05-30 |
ファーマサイクリックス エルエルシー |
ベンダムスチンと組み合わせたヒストンデアセチラーゼ阻害剤の製剤とその使用
|
|
JP6800750B2
(ja)
|
2013-08-02 |
2020-12-16 |
ファーマサイクリックス エルエルシー |
固形腫瘍の処置方法
|