JP2014525239A5 - - Google Patents
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- Publication number
- JP2014525239A5 JP2014525239A5 JP2014526229A JP2014526229A JP2014525239A5 JP 2014525239 A5 JP2014525239 A5 JP 2014525239A5 JP 2014526229 A JP2014526229 A JP 2014526229A JP 2014526229 A JP2014526229 A JP 2014526229A JP 2014525239 A5 JP2014525239 A5 JP 2014525239A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- leucine
- acid sequence
- seq
- sucrose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 150000001413 amino acids Chemical group 0.000 claims description 42
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 24
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims description 24
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims description 20
- 238000000034 method Methods 0.000 claims description 18
- 241000894006 Bacteria Species 0.000 claims description 16
- 235000001014 amino acid Nutrition 0.000 claims description 16
- ALRHLSYJTWAHJZ-UHFFFAOYSA-N 3-hydroxypropionic acid Chemical compound OCCC(O)=O ALRHLSYJTWAHJZ-UHFFFAOYSA-N 0.000 claims description 14
- 229930006000 Sucrose Natural products 0.000 claims description 14
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 14
- 239000005720 sucrose Substances 0.000 claims description 14
- 229920001184 polypeptide Polymers 0.000 claims description 11
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 11
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 11
- DNIAPMSPPWPWGF-VKHMYHEASA-N (+)-propylene glycol Chemical compound C[C@H](O)CO DNIAPMSPPWPWGF-VKHMYHEASA-N 0.000 claims description 9
- YPFDHNVEDLHUCE-UHFFFAOYSA-N 1,3-propanediol Substances OCCCO YPFDHNVEDLHUCE-UHFFFAOYSA-N 0.000 claims description 9
- 229920000166 polytrimethylene carbonate Polymers 0.000 claims description 9
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims description 8
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 claims description 8
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 claims description 8
- 125000000487 histidyl group Chemical group [H]N([H])C(C(=O)O*)C([H])([H])C1=C([H])N([H])C([H])=N1 0.000 claims description 8
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 claims description 8
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 claims description 6
- 239000002773 nucleotide Substances 0.000 claims description 5
- 125000003729 nucleotide group Chemical group 0.000 claims description 5
- 239000004471 Glycine Substances 0.000 claims description 4
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 claims description 4
- 235000018417 cysteine Nutrition 0.000 claims description 4
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims description 4
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 claims description 4
- 125000001909 leucine group Chemical group [H]N(*)C(C(*)=O)C([H])([H])C(C([H])([H])[H])C([H])([H])[H] 0.000 claims description 4
- 125000001500 prolyl group Chemical group [H]N1C([H])(C(=O)[*])C([H])([H])C([H])([H])C1([H])[H] 0.000 claims description 4
- 125000000430 tryptophan group Chemical group [H]N([H])C(C(=O)O*)C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12 0.000 claims description 4
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 claims description 4
- 125000001493 tyrosinyl group Chemical group [H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 claims description 4
- 101710173142 Beta-fructofuranosidase, cell wall isozyme Proteins 0.000 claims description 3
- 238000012258 culturing Methods 0.000 claims description 3
- ONIBWKKTOPOVIA-SCSAIBSYSA-N D-Proline Chemical compound OC(=O)[C@H]1CCCN1 ONIBWKKTOPOVIA-SCSAIBSYSA-N 0.000 claims description 2
- 238000000855 fermentation Methods 0.000 description 4
- 230000004151 fermentation Effects 0.000 description 4
- 108090000156 Fructokinases Proteins 0.000 description 3
- 102000003793 Fructokinases Human genes 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 241000588722 Escherichia Species 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 102000005548 Hexokinase Human genes 0.000 description 1
- 102100023418 Ketohexokinase Human genes 0.000 description 1
- 241000588748 Klebsiella Species 0.000 description 1
- 239000003054 catalyst Substances 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 238000010924 continuous production Methods 0.000 description 1
- 238000010908 decantation Methods 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 150000002314 glycerols Chemical class 0.000 description 1
- 238000000622 liquid--liquid extraction Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/210,488 US8629243B2 (en) | 2011-08-16 | 2011-08-16 | Variant sucrose transporter polypeptides that enable faster sucrose utilization in bacteria |
| US13/210,488 | 2011-08-16 | ||
| PCT/US2012/051222 WO2013025945A2 (en) | 2011-08-16 | 2012-08-16 | Variant sucrose transporter polypeptides that enable faster sucrose utilization in bacteria |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014525239A JP2014525239A (ja) | 2014-09-29 |
| JP2014525239A5 true JP2014525239A5 (enExample) | 2015-08-06 |
Family
ID=47712908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014526229A Abandoned JP2014525239A (ja) | 2011-08-16 | 2012-08-16 | 細菌中でより迅速なスクロース利用ができるようにする変種スクロース輸送ポリペプチド |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8629243B2 (enExample) |
| EP (1) | EP2744818A4 (enExample) |
| JP (1) | JP2014525239A (enExample) |
| KR (1) | KR20140054233A (enExample) |
| CN (1) | CN103717611A (enExample) |
| AU (1) | AU2012296494A1 (enExample) |
| BR (1) | BR112014003600A2 (enExample) |
| IN (1) | IN2014DN00161A (enExample) |
| WO (1) | WO2013025945A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9017961B2 (en) | 2012-03-05 | 2015-04-28 | E.I. Du Pont De Nemours And Company | Recombinant bacteria comprising novel sucrose transporters |
| US8686114B2 (en) * | 2012-03-05 | 2014-04-01 | E I Du Pont De Nemours And Company | Variant sucrose transporter polypeptides |
| KR101588862B1 (ko) | 2015-01-19 | 2016-01-26 | (주)제이앤푸드 | 수용성 보리차 분말의 제조 방법 |
| CN105331618A (zh) * | 2015-11-16 | 2016-02-17 | 华南农业大学 | 一种小桐子蔗糖转运蛋白同源基因的克隆方法 |
| CN107236754B (zh) * | 2016-03-28 | 2021-02-05 | 中国科学院青岛生物能源与过程研究所 | 利用聚球藻utex2973生产糖类化合物的构建体、菌株与方法 |
| CN105779404B (zh) * | 2016-05-11 | 2019-04-16 | 广西大学 | 一种蔗糖磷酸化酶的突变体t155s及其应用 |
| WO2020090017A1 (ja) * | 2018-10-30 | 2020-05-07 | Ｇｒｅｅｎ Ｅａｒｔｈ Ｉｎｓｔｉｔｕｔｅ 株式会社 | １，３－プロパンジオールの製造方法 |
| CN114591933B (zh) * | 2019-05-24 | 2023-09-22 | 山东大学 | Pet降解酶突变体及其应用 |
| US20240035004A1 (en) * | 2020-12-18 | 2024-02-01 | Inbiose N.V. | Variant sucrose permease polypeptides |
| WO2023168233A1 (en) * | 2022-03-03 | 2023-09-07 | Cargill, Incorporated | Genetically modified yeast and fermentation processes for the production of 3-hydroxypropionate |
| WO2023168244A1 (en) * | 2022-03-03 | 2023-09-07 | Cargill, Incorporated | Genetically modified yeast and fermentation processes for the production of 3-hydroxypropionate |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999053068A2 (en) * | 1998-04-09 | 1999-10-21 | E.I. Du Pont De Nemours And Company | Sucrose transporters from plants |
| RU2212447C2 (ru) | 2000-04-26 | 2003-09-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Штамм escherichia coli - продуцент аминокислоты (варианты) и способ получения аминокислот (варианты) |
| JP4814794B2 (ja) | 2003-05-06 | 2011-11-16 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | 生物学的に生産された１，３−プロパンジオールの精製 |
| US9297028B2 (en) * | 2005-09-29 | 2016-03-29 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| EP2227541B1 (en) | 2007-12-18 | 2013-06-19 | Korea Advanced Institute of Science and Technology | Recombinant microorganism having an ability of using sucrose as a carbon source |
| MX2011004842A (es) | 2008-11-07 | 2011-05-30 | Metabolic Explorer Sa | Uso de sacarosa como sustrato para la produccion fermentativa de 1,2-propanodiol. |
| BR112012012374A2 (pt) * | 2009-11-23 | 2015-09-15 | Du Pont | semente de planta com maior teor de óleo, planta, método para aumentar ainda mais o teor de óleo em uma semente de planta de alto teor de óleo, método par avaliar o teor de óleo aumentado em uma semente de planta, polinucleotídeo isolado polipeptídeo isolado |
| US20110136190A1 (en) * | 2009-12-04 | 2011-06-09 | E. I. Du Pont De Nemours And Company | Recombinant bacteria for producing glycerol and glycerol-derived products from sucrose |
-
2011
- 2011-08-16 US US13/210,488 patent/US8629243B2/en not_active Expired - Fee Related
-
2012
- 2012-08-16 JP JP2014526229A patent/JP2014525239A/ja not_active Abandoned
- 2012-08-16 CN CN201280039390.2A patent/CN103717611A/zh active Pending
- 2012-08-16 WO PCT/US2012/051222 patent/WO2013025945A2/en not_active Ceased
- 2012-08-16 AU AU2012296494A patent/AU2012296494A1/en not_active Abandoned
- 2012-08-16 KR KR1020147006605A patent/KR20140054233A/ko not_active Withdrawn
- 2012-08-16 IN IN161DEN2014 patent/IN2014DN00161A/en unknown
- 2012-08-16 EP EP12823356.6A patent/EP2744818A4/en not_active Withdrawn
- 2012-08-16 BR BR112014003600A patent/BR112014003600A2/pt not_active IP Right Cessation
-
2013
- 2013-12-05 US US14/097,727 patent/US20140093927A1/en not_active Abandoned
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