|
US9528160B2
(en)
|
2008-11-07 |
2016-12-27 |
Adaptive Biotechnolgies Corp. |
Rare clonotypes and uses thereof
|
|
GB2483810B
(en)
|
2008-11-07 |
2012-09-05 |
Sequenta Inc |
Methods for correlating clonotypes with diseases in a population
|
|
US9365901B2
(en)
|
2008-11-07 |
2016-06-14 |
Adaptive Biotechnologies Corp. |
Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia
|
|
US9506119B2
(en)
|
2008-11-07 |
2016-11-29 |
Adaptive Biotechnologies Corp. |
Method of sequence determination using sequence tags
|
|
US8748103B2
(en)
|
2008-11-07 |
2014-06-10 |
Sequenta, Inc. |
Monitoring health and disease status using clonotype profiles
|
|
US8628927B2
(en)
|
2008-11-07 |
2014-01-14 |
Sequenta, Inc. |
Monitoring health and disease status using clonotype profiles
|
|
EP2387627B1
(en)
|
2009-01-15 |
2016-03-30 |
Adaptive Biotechnologies Corporation |
Adaptive immunity profiling and methods for generation of monoclonal antibodies
|
|
US20100330571A1
(en)
|
2009-06-25 |
2010-12-30 |
Robins Harlan S |
Method of measuring adaptive immunity
|
|
US8835358B2
(en)
|
2009-12-15 |
2014-09-16 |
Cellular Research, Inc. |
Digital counting of individual molecules by stochastic attachment of diverse labels
|
|
WO2012019168A2
(en)
|
2010-08-06 |
2012-02-09 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
ES3005233T3
(en)
|
2010-10-01 |
2025-03-14 |
Modernatx Inc |
Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
|
|
DE12722942T1
(de)
|
2011-03-31 |
2021-09-30 |
Modernatx, Inc. |
Freisetzung und formulierung von manipulierten nukleinsäuren
|
|
LT3473267T
(lt)
|
2011-05-24 |
2021-11-25 |
BioNTech SE |
Individualizuotos vakcinos nuo vėžio
|
|
US10385475B2
(en)
|
2011-09-12 |
2019-08-20 |
Adaptive Biotechnologies Corp. |
Random array sequencing of low-complexity libraries
|
|
AU2012325791B2
(en)
|
2011-10-21 |
2018-04-05 |
Adaptive Biotechnologies Corporation |
Quantification of adaptive immune cell genomes in a complex mixture of cells
|
|
EP3904536B1
(en)
|
2011-12-09 |
2025-10-29 |
Adaptive Biotechnologies Corporation |
Diagnosis of lymphoid malignancies and minimal residual disease detection
|
|
US9499865B2
(en)
|
2011-12-13 |
2016-11-22 |
Adaptive Biotechnologies Corp. |
Detection and measurement of tissue-infiltrating lymphocytes
|
|
AU2012352180A1
(en)
|
2011-12-16 |
2014-07-31 |
Moderna Therapeutics, Inc. |
Modified nucleoside, nucleotide, and nucleic acid compositions
|
|
US10941396B2
(en)
|
2012-02-27 |
2021-03-09 |
Becton, Dickinson And Company |
Compositions and kits for molecular counting
|
|
EP2823060B1
(en)
|
2012-03-05 |
2018-02-14 |
Adaptive Biotechnologies Corporation |
Determining paired immune receptor chains from frequency matched subunits
|
|
US9572897B2
(en)
|
2012-04-02 |
2017-02-21 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
|
WO2013151663A1
(en)
|
2012-04-02 |
2013-10-10 |
modeRNA Therapeutics |
Modified polynucleotides for the production of membrane proteins
|
|
US9254311B2
(en)
|
2012-04-02 |
2016-02-09 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of proteins
|
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
|
BR112014027309A2
(pt)
|
2012-05-08 |
2017-07-11 |
Adaptive Biotechnologies Corp |
composições e métodos para medir e calibrar a tendên-cia de amplificação em reações de pcr multiplexadas
|
|
MX364370B
(es)
*
|
2012-07-12 |
2019-04-24 |
Persimmune Inc |
Vacunas contra el cancer personalizadas y terapias de celulas inmunes adoptivas.
|
|
EP2885419A4
(en)
|
2012-08-14 |
2016-05-25 |
Moderna Therapeutics Inc |
ENZYMES AND POLYMERASES FOR RNA SYNTHESIS
|
|
US10501801B2
(en)
|
2012-09-28 |
2019-12-10 |
University Of Connecticut |
Identification of tumor-protective epitopes for the treatment of cancers
|
|
CN105189779B
(zh)
|
2012-10-01 |
2018-05-11 |
适应生物技术公司 |
通过适应性免疫受体多样性和克隆性表征进行的免疫能力评估
|
|
HRP20220607T1
(hr)
|
2012-11-26 |
2022-06-24 |
Modernatx, Inc. |
Terminalno modificirana rna
|
|
US10155031B2
(en)
*
|
2012-11-28 |
2018-12-18 |
Biontech Rna Pharmaceuticals Gmbh |
Individualized vaccines for cancer
|
|
WO2014093186A1
(en)
*
|
2012-12-12 |
2014-06-19 |
Garvin Alex M |
Non-invasive detection of colorectal neoplasia using circular consensus sequencing
|
|
WO2014113204A1
(en)
|
2013-01-17 |
2014-07-24 |
Personalis, Inc. |
Methods and systems for genetic analysis
|
|
EP2968391A1
(en)
|
2013-03-13 |
2016-01-20 |
Moderna Therapeutics, Inc. |
Long-lived polynucleotide molecules
|
|
EP2971010B1
(en)
|
2013-03-14 |
2020-06-10 |
ModernaTX, Inc. |
Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions
|
|
CA2906218A1
(en)
*
|
2013-03-15 |
2014-09-18 |
Adaptive Biotechnologies Corporation |
Uniquely tagged rearranged adaptive immune receptor genes in a complex gene set
|
|
CN118750591A
(zh)
*
|
2013-04-07 |
2024-10-11 |
博德研究所 |
用于个性化瘤形成疫苗的组合物和方法
|
|
WO2014180490A1
(en)
*
|
2013-05-10 |
2014-11-13 |
Biontech Ag |
Predicting immunogenicity of t cell epitopes
|
|
US9708657B2
(en)
|
2013-07-01 |
2017-07-18 |
Adaptive Biotechnologies Corp. |
Method for generating clonotype profiles using sequence tags
|
|
US20160186260A1
(en)
*
|
2013-07-26 |
2016-06-30 |
Sequenta, Llc |
Cancer vaccination with antigen evolution
|
|
EP3039158B1
(en)
|
2013-08-28 |
2018-11-14 |
Cellular Research, Inc. |
Massively parallel single cell analysis
|
|
GB2534067B
(en)
|
2013-08-30 |
2021-07-21 |
Personalis Inc |
Methods and systems for genomic analysis
|
|
EP3052106A4
(en)
|
2013-09-30 |
2017-07-19 |
ModernaTX, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
|
WO2015051275A1
(en)
|
2013-10-03 |
2015-04-09 |
Personalis, Inc. |
Methods for analyzing genotypes
|
|
EP3055676A1
(en)
|
2013-10-07 |
2016-08-17 |
Cellular Research, Inc. |
Methods and systems for digitally counting features on arrays
|
|
WO2015077717A1
(en)
|
2013-11-25 |
2015-05-28 |
The Broad Institute Inc. |
Compositions and methods for diagnosing, evaluating and treating cancer by means of the dna methylation status
|
|
DK3077539T3
(en)
*
|
2013-12-02 |
2018-11-19 |
Personal Genome Diagnostics Inc |
Procedure for evaluating minority variations in a sample
|
|
WO2015085147A1
(en)
|
2013-12-05 |
2015-06-11 |
The Broad Institute Inc. |
Polymorphic gene typing and somatic change detection using sequencing data
|
|
EP3076992B1
(en)
*
|
2013-12-06 |
2022-04-06 |
The Broad Institute, Inc. |
Formulations for neoplasia vaccines
|
|
CA2934073A1
(en)
*
|
2013-12-20 |
2015-06-25 |
The Broad Institute, Inc. |
Combination therapy with neoantigen vaccine
|
|
ES2741740T3
(es)
|
2014-03-05 |
2020-02-12 |
Adaptive Biotechnologies Corp |
Métodos que usan moléculas sintéticas que contienen segmentos de nucleótidos aleatorios
|
|
US10066265B2
(en)
|
2014-04-01 |
2018-09-04 |
Adaptive Biotechnologies Corp. |
Determining antigen-specific t-cells
|
|
ES2777529T3
(es)
|
2014-04-17 |
2020-08-05 |
Adaptive Biotechnologies Corp |
Cuantificación de genomas de células inmunitarias adaptativas en una mezcla compleja de células
|
|
ES3009962T3
(en)
|
2014-04-23 |
2025-03-31 |
Modernatx Inc |
Nucleic acid vaccines
|
|
US10017759B2
(en)
*
|
2014-06-26 |
2018-07-10 |
Illumina, Inc. |
Library preparation of tagged nucleic acid
|
|
US10564165B2
(en)
|
2014-09-10 |
2020-02-18 |
Genentech, Inc. |
Identification of immunogenic mutant peptides using genomic, transcriptomic and proteomic information
|
|
US11338026B2
(en)
|
2014-09-10 |
2022-05-24 |
The University Of Connecticut |
Identification of immunologically protective neo-epitopes for the treatment of cancers
|
|
CA2963364A1
(en)
|
2014-10-02 |
2016-04-07 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods of isolating t cells having antigenic specificity for a cancer-specific mutation
|
|
US10392663B2
(en)
|
2014-10-29 |
2019-08-27 |
Adaptive Biotechnologies Corp. |
Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from a large number of samples
|
|
EP3212808B1
(en)
|
2014-10-30 |
2022-03-02 |
Personalis, Inc. |
Methods for using mosaicism in nucleic acids sampled distal to their origin
|
|
US10246701B2
(en)
|
2014-11-14 |
2019-04-02 |
Adaptive Biotechnologies Corp. |
Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture
|
|
AU2015353581A1
(en)
|
2014-11-25 |
2017-06-15 |
Adaptive Biotechnologies Corporation |
Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing
|
|
ES3049406T3
(en)
|
2014-12-19 |
2025-12-16 |
Broad Inst Inc |
Methods for profiling the t-cell-receptor repertoire
|
|
EP3234193B1
(en)
|
2014-12-19 |
2020-07-15 |
Massachusetts Institute of Technology |
Molecular biomarkers for cancer immunotherapy
|
|
WO2016128060A1
(en)
*
|
2015-02-12 |
2016-08-18 |
Biontech Ag |
Predicting t cell epitopes useful for vaccination
|
|
WO2016134078A1
(en)
*
|
2015-02-19 |
2016-08-25 |
Becton, Dickinson And Company |
High-throughput single-cell analysis combining proteomic and genomic information
|
|
ES2858306T3
(es)
|
2015-02-24 |
2021-09-30 |
Adaptive Biotechnologies Corp |
Método para determinar el estado de HLA mediante secuenciación del repertorio inmunitario
|
|
EP3261605B2
(en)
|
2015-02-26 |
2022-04-20 |
SiO2 Medical Products, Inc. |
Cycloolefin polymer container with a scratch resistant and anti-static coating
|
|
US9727810B2
(en)
|
2015-02-27 |
2017-08-08 |
Cellular Research, Inc. |
Spatially addressable molecular barcoding
|
|
JP7508191B2
(ja)
|
2015-03-30 |
2024-07-01 |
ベクトン・ディキンソン・アンド・カンパニー |
コンビナトリアルバーコーディングのための方法および組成物
|
|
AU2016242967B2
(en)
|
2015-04-01 |
2021-07-01 |
Adaptive Biotechnologies Corp. |
Method of identifying human compatible T cell receptors specific for an antigenic target
|
|
WO2016172373A1
(en)
|
2015-04-23 |
2016-10-27 |
Cellular Research, Inc. |
Methods and compositions for whole transcriptome amplification
|
|
CN107750278B
(zh)
*
|
2015-04-27 |
2023-10-03 |
癌症研究技术有限公司 |
治疗癌症的方法
|
|
WO2016180467A1
(en)
|
2015-05-11 |
2016-11-17 |
Biontech Cell & Gene Therapies Gmbh |
Enhancing the effect of car-engineered t cells by means of nucleic acid vaccination
|
|
MX392028B
(es)
*
|
2015-05-13 |
2025-03-04 |
Agenus Inc |
Vacunas para el tratamiento y prevención del cáncer.
|
|
PE20180670A1
(es)
|
2015-05-20 |
2018-04-19 |
Broad Inst Inc |
Neoantigenos compartidos
|
|
WO2016196229A1
(en)
|
2015-06-01 |
2016-12-08 |
Cellular Research, Inc. |
Methods for rna quantification
|
|
TW202241500A
(zh)
*
|
2015-06-09 |
2022-11-01 |
美商博德研究所有限公司 |
用於贅瘤疫苗之調配物及其製備方法
|
|
MA42543A
(fr)
*
|
2015-07-30 |
2018-06-06 |
Modernatx Inc |
Arn épitope peptidiques concatémériques
|
|
GB201516047D0
(en)
|
2015-09-10 |
2015-10-28 |
Cancer Rec Tech Ltd |
Method
|
|
KR102395450B1
(ko)
|
2015-09-11 |
2022-05-09 |
셀룰러 리서치, 인크. |
핵산 라이브러리 정규화를 위한 방법 및 조성물
|
|
US10849920B2
(en)
|
2015-10-05 |
2020-12-01 |
Modernatx, Inc. |
Methods for therapeutic administration of messenger ribonucleic acid drugs
|
|
KR20250161050A
(ko)
*
|
2015-10-12 |
2025-11-14 |
난토믹스, 엘엘씨 |
바이러스성 암 네오에피토프를 위한 조성물 및 방법
|
|
MX387275B
(es)
*
|
2015-10-12 |
2025-03-18 |
Nantomics Llc |
Neoepítopos virales y sus usos
|
|
JP2018532777A
(ja)
*
|
2015-10-22 |
2018-11-08 |
モデルナティーエックス, インコーポレイテッド |
癌ワクチン
|
|
EP3389630B1
(en)
|
2015-12-16 |
2023-11-08 |
Gritstone bio, Inc. |
Neoantigen identification, manufacture, and use
|
|
CN105349533A
(zh)
*
|
2015-12-21 |
2016-02-24 |
生工生物工程(上海)股份有限公司 |
构建链特异性转录组文库的方法
|
|
WO2017118702A1
(en)
*
|
2016-01-08 |
2017-07-13 |
Vaccibody As |
Neoepitope rna cancer vaccine
|
|
CA3008437A1
(en)
*
|
2016-01-08 |
2017-07-13 |
Vaccibody As |
Therapeutic anticancer neoepitope vaccine
|
|
US11154597B2
(en)
|
2016-03-24 |
2021-10-26 |
Nantcell, Inc. |
Sequence arrangements and sequences for neoepitope presentation
|
|
SG11201808196UA
(en)
|
2016-03-31 |
2018-10-30 |
Neon Therapeutics Inc |
Neoantigens and methods of their use
|
|
EP3446119A1
(en)
|
2016-04-18 |
2019-02-27 |
The Broad Institute Inc. |
Improved hla epitope prediction
|
|
EP3445392A1
(en)
*
|
2016-04-22 |
2019-02-27 |
CureVac AG |
Rna encoding a tumor antigen
|
|
EP3452614B1
(en)
|
2016-05-02 |
2023-06-28 |
Becton, Dickinson and Company |
Accurate molecular barcoding
|
|
CA3022924A1
(en)
*
|
2016-05-04 |
2017-11-09 |
Immunovaccine Technologies Inc. |
Vaccine compositions comprising an amphipathic compound, a neoantigen and a hydrophobic carrier, and methods of use thereof
|
|
WO2017194170A1
(en)
|
2016-05-13 |
2017-11-16 |
Biontech Rna Pharmaceuticals Gmbh |
Methods for predicting the usefulness of proteins or protein fragments for immunotherapy
|
|
US10301677B2
(en)
|
2016-05-25 |
2019-05-28 |
Cellular Research, Inc. |
Normalization of nucleic acid libraries
|
|
EP3465502B1
(en)
|
2016-05-26 |
2024-04-10 |
Becton, Dickinson and Company |
Molecular label counting adjustment methods
|
|
KR20200138418A
(ko)
*
|
2016-05-27 |
2020-12-09 |
이투빅스 코포레이션 |
네오에피토프 백신 조성물 및 이의 사용 방법
|
|
US11299783B2
(en)
|
2016-05-27 |
2022-04-12 |
Personalis, Inc. |
Methods and systems for genetic analysis
|
|
US10202641B2
(en)
|
2016-05-31 |
2019-02-12 |
Cellular Research, Inc. |
Error correction in amplification of samples
|
|
US10640763B2
(en)
|
2016-05-31 |
2020-05-05 |
Cellular Research, Inc. |
Molecular indexing of internal sequences
|
|
SG11201811258UA
(en)
*
|
2016-07-13 |
2019-01-30 |
Vaximm Ag |
Process for the production of a dna vaccine for cancer immunotherapy
|
|
LT3488443T
(lt)
*
|
2016-07-20 |
2021-10-25 |
BioNTech SE |
Neoepitopų, kaip ligai specifinių taikinių, parinkimas padidinto efektyvumo terapijai
|
|
US10428325B1
(en)
|
2016-09-21 |
2019-10-01 |
Adaptive Biotechnologies Corporation |
Identification of antigen-specific B cell receptors
|
|
EP3516400B1
(en)
|
2016-09-26 |
2023-08-16 |
Becton, Dickinson and Company |
Measurement of protein expression using reagents with barcoded oligonucleotide sequences
|
|
KR102790039B1
(ko)
|
2016-11-08 |
2025-04-04 |
벡톤 디킨슨 앤드 컴퍼니 |
세포 표지 분류 방법
|
|
ES2980967T3
(es)
|
2016-11-08 |
2024-10-03 |
Becton Dickinson Co |
Métodos para la clasificación de perfiles de expresión
|
|
US20190321481A1
(en)
|
2016-11-11 |
2019-10-24 |
Nantbio, Inc. |
Immunomodulatory compositions, processes for making the same, and methods for inhibiting cytokine storms
|
|
CN108090325B
(zh)
*
|
2016-11-23 |
2022-01-25 |
中国科学院昆明动物研究所 |
一种应用β-稳定性分析单细胞测序数据的方法
|
|
WO2018132753A1
(en)
*
|
2017-01-13 |
2018-07-19 |
Nantbio, Inc. |
Validation of neoepitope-based treatment
|
|
JP7104048B2
(ja)
|
2017-01-13 |
2022-07-20 |
セルラー リサーチ, インコーポレイテッド |
流体チャネルの親水性コーティング
|
|
US12331359B2
(en)
*
|
2017-01-18 |
2025-06-17 |
Michael Laessig |
Neoantigens and uses thereof for treating cancer
|
|
EP3574116A1
(en)
|
2017-01-24 |
2019-12-04 |
The Broad Institute, Inc. |
Compositions and methods for detecting a mutant variant of a polynucleotide
|
|
EP3576780A1
(en)
|
2017-02-01 |
2019-12-11 |
Modernatx, Inc. |
Immunomodulatory therapeutic mrna compositions encoding activating oncogene mutation peptides
|
|
KR20190120233A
(ko)
*
|
2017-02-01 |
2019-10-23 |
모더나티엑스, 인크. |
Rna 암 백신
|
|
US11319583B2
(en)
|
2017-02-01 |
2022-05-03 |
Becton, Dickinson And Company |
Selective amplification using blocking oligonucleotides
|
|
FI3580561T3
(fi)
|
2017-02-12 |
2023-12-12 |
Biontech Us Inc |
Hla-pohjaiset menetelmät ja koostumukset sekä niiden käyttö
|
|
CA3057505A1
(en)
|
2017-03-31 |
2018-10-04 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods of treating t cell exhaustion by inhibiting or modulating t cell receptor signaling
|
|
CN118370809A
(zh)
|
2017-04-03 |
2024-07-23 |
百欧恩泰美国公司 |
蛋白质抗原及其用途
|
|
MA48047A
(fr)
|
2017-04-05 |
2020-02-12 |
Modernatx Inc |
Réduction ou élimination de réponses immunitaires à des protéines thérapeutiques administrées par voie non intraveineuse, par exemple par voie sous-cutanée
|
|
SG11201909882SA
(en)
|
2017-04-24 |
2019-11-28 |
Nantcell Inc |
Targeted neoepitope vectors and methods therefor
|
|
TW201907937A
(zh)
|
2017-05-08 |
2019-03-01 |
美商葛利史東腫瘤科技公司 |
阿爾法病毒新抗原載體
|
|
CA3062883C
(en)
|
2017-05-11 |
2024-04-02 |
Theralase Biotech, Inc. |
Vaccine containing cancer cells inactivated by photodynamic treatment with metal-based coordination complexes, and immunotherapy method using same
|
|
EP3933408A1
(en)
|
2017-05-30 |
2022-01-05 |
Nant Holdings IP LLC |
Circulating tumor cell enrichment using neoepitopes
|
|
JP7536450B2
(ja)
|
2017-06-05 |
2024-08-20 |
ベクトン・ディキンソン・アンド・カンパニー |
単一細胞用のサンプルインデックス付加
|
|
WO2018224166A1
(en)
*
|
2017-06-09 |
2018-12-13 |
Biontech Rna Pharmaceuticals Gmbh |
Methods for predicting the usefulness of disease specific amino acid modifications for immunotherapy
|
|
JP7334124B2
(ja)
|
2017-06-21 |
2023-08-28 |
トランジェーヌ |
個別化ワクチン
|
|
US20200219586A1
(en)
|
2017-06-27 |
2020-07-09 |
Institute For Cancer Research D/B/A The Research Institute Of Fox Chase Cancer Center |
MHC-1 Genotypes Restricts The Oncogenic Mutational Landscape
|
|
IL271965B2
(en)
*
|
2017-07-12 |
2023-03-01 |
Nouscom Ag |
Preparations containing a neoantigenic vaccine for the treatment of cancer
|
|
US10636512B2
(en)
|
2017-07-14 |
2020-04-28 |
Cofactor Genomics, Inc. |
Immuno-oncology applications using next generation sequencing
|
|
US12504380B2
(en)
|
2017-09-25 |
2025-12-23 |
University Of Florida Research Foundation, Incorporated |
Immunoassays for detection of ran proteins
|
|
JP7227237B2
(ja)
|
2017-10-10 |
2023-02-21 |
グリットストーン バイオ インコーポレイテッド |
ホットスポットを利用した新生抗原の特定
|
|
CN111630602A
(zh)
*
|
2017-11-22 |
2020-09-04 |
磨石肿瘤生物技术公司 |
减少新抗原的接合表位呈递
|
|
US20200354730A1
(en)
*
|
2017-11-27 |
2020-11-12 |
Nantcell, Inc. |
Improved Yeast Polytope Vaccine Compositions And Methods
|
|
US11254980B1
(en)
|
2017-11-29 |
2022-02-22 |
Adaptive Biotechnologies Corporation |
Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements
|
|
WO2019105485A1
(zh)
*
|
2017-12-01 |
2019-06-06 |
上海桀蒙生物技术有限公司 |
个性化癌症疫苗的制备方法
|
|
WO2019126186A1
(en)
|
2017-12-18 |
2019-06-27 |
Neon Therapeutics, Inc. |
Neoantigens and uses thereof
|
|
WO2019125864A1
(en)
|
2017-12-18 |
2019-06-27 |
Personal Genome Diagnostics Inc. |
Machine learning system and method for somatic mutation discovery
|
|
CN111492068B
(zh)
|
2017-12-19 |
2025-03-21 |
贝克顿迪金森公司 |
与寡核苷酸相关联的颗粒
|
|
AU2019205330B2
(en)
|
2018-01-04 |
2025-09-11 |
Iconic Therapeutics Llc |
Anti-tissue factor antibodies, antibody-drug conjugates, and related methods
|
|
US20210005285A1
(en)
*
|
2018-03-14 |
2021-01-07 |
Koninklijke Philips N.V. |
System and method using local unique features to interpret transcript expression levels for rna sequencing data
|
|
AU2019244115A1
(en)
*
|
2018-03-30 |
2020-11-19 |
Juno Diagnostics, Inc. |
Deep learning-based methods, devices, and systems for prenatal testing
|
|
CA3096909A1
(en)
|
2018-04-26 |
2019-10-31 |
Agenus Inc. |
Heat shock protein-binding peptide compositions and methods of use thereof
|
|
CN112272710A
(zh)
|
2018-05-03 |
2021-01-26 |
贝克顿迪金森公司 |
高通量多组学样品分析
|
|
CN118910215A
(zh)
|
2018-05-03 |
2024-11-08 |
贝克顿迪金森公司 |
在相对的转录物末端进行分子条形码化
|
|
IL259392A
(en)
|
2018-05-15 |
2018-08-01 |
Yeda Res & Dev |
Vaccination with cancer neoantigens
|
|
WO2019227106A1
(en)
*
|
2018-05-25 |
2019-11-28 |
The Wistar Institute |
Tumor-specific neoantigens and methods of using the same
|
|
CN108897986B
(zh)
*
|
2018-05-29 |
2020-11-27 |
中南大学 |
一种基于蛋白质信息的基因组序列拼接方法
|
|
US10801064B2
(en)
|
2018-05-31 |
2020-10-13 |
Personalis, Inc. |
Compositions, methods and systems for processing or analyzing multi-species nucleic acid samples
|
|
US11814750B2
(en)
|
2018-05-31 |
2023-11-14 |
Personalis, Inc. |
Compositions, methods and systems for processing or analyzing multi-species nucleic acid samples
|
|
JP7534962B2
(ja)
|
2018-06-19 |
2024-08-15 |
ビオンテック ユーエス インコーポレイテッド |
ネオ抗原およびその使用
|
|
KR20210038886A
(ko)
*
|
2018-06-27 |
2021-04-08 |
모더나티엑스, 인크. |
개인화된 암 백신 에피토프 선택
|
|
WO2020020444A1
(en)
*
|
2018-07-24 |
2020-01-30 |
Biontech Rna Pharmaceuticals Gmbh |
Individualized vaccines for cancer
|
|
WO2020022897A1
(en)
|
2018-07-26 |
2020-01-30 |
Frame Pharmaceuticals B.V. |
Method of preparing subject-specific immunogenic compositions based on a neo open-reading-frame peptide database
|
|
MX2021003654A
(es)
|
2018-09-27 |
2021-05-28 |
Nykode Therapeutics AS |
Metodo para seleccionar neoepitopes.
|
|
US11639517B2
(en)
|
2018-10-01 |
2023-05-02 |
Becton, Dickinson And Company |
Determining 5′ transcript sequences
|
|
US20210382068A1
(en)
|
2018-10-02 |
2021-12-09 |
Dana-Farber Cancer Institute, Inc. |
Hla single allele lines
|
|
CN114573688A
(zh)
*
|
2018-10-19 |
2022-06-03 |
杭州纽安津生物科技有限公司 |
通用性多肽疫苗及其在制备治疗/预防胰腺癌药物中的应用
|
|
CA3118947A1
(en)
*
|
2018-11-07 |
2020-05-14 |
Modernatx, Inc. |
Rna cancer vaccines
|
|
US11932849B2
(en)
|
2018-11-08 |
2024-03-19 |
Becton, Dickinson And Company |
Whole transcriptome analysis of single cells using random priming
|
|
AU2019379306B2
(en)
*
|
2018-11-15 |
2025-03-06 |
Nouscom Ag |
Selection of cancer mutations for generation of a personalized cancer vaccine
|
|
CN113195717A
(zh)
|
2018-12-13 |
2021-07-30 |
贝克顿迪金森公司 |
单细胞全转录组分析中的选择性延伸
|
|
WO2020131586A2
(en)
|
2018-12-17 |
2020-06-25 |
The Broad Institute, Inc. |
Methods for identifying neoantigens
|
|
CN113474840B
(zh)
*
|
2018-12-21 |
2024-12-17 |
百欧恩泰美国公司 |
用于预测hla ii类特异性表位及表征cd4+ t细胞的方法和系统
|
|
GB201821207D0
(en)
|
2018-12-24 |
2019-02-06 |
Tcer Ab |
Immunotherapy therapy
|
|
GB201821205D0
(en)
*
|
2018-12-24 |
2019-02-06 |
Tcer Ab |
Immunotherapy
|
|
US20220093217A1
(en)
*
|
2019-01-08 |
2022-03-24 |
Caris Mpi, Inc. |
Genomic profiling similarity
|
|
AU2020208193A1
(en)
*
|
2019-01-14 |
2021-07-29 |
BioNTech SE |
Methods of treating cancer with a PD-1 axis binding antagonist and an RNA vaccine
|
|
WO2020150356A1
(en)
|
2019-01-16 |
2020-07-23 |
Becton, Dickinson And Company |
Polymerase chain reaction normalization through primer titration
|
|
EP4242322B1
(en)
|
2019-01-23 |
2024-08-21 |
Becton, Dickinson and Company |
Oligonucleotides associated with antibodies
|
|
EP3921443A1
(en)
|
2019-02-08 |
2021-12-15 |
F. Hoffmann-La Roche AG |
Diagnostic and therapeutic methods for cancer
|
|
US12071617B2
(en)
|
2019-02-14 |
2024-08-27 |
Becton, Dickinson And Company |
Hybrid targeted and whole transcriptome amplification
|
|
WO2020167240A1
(en)
*
|
2019-02-15 |
2020-08-20 |
Rjan Holdng Ab |
Autologous cancer tumour associated extrachromosomal circular dna for use as a therapeutic vaccine
|
|
AU2020232971A1
(en)
*
|
2019-03-01 |
2021-09-23 |
Scott R. BURKHOLZ |
Design, manufacture, and use of personalized cancer vaccines
|
|
WO2020184551A1
(ja)
|
2019-03-13 |
2020-09-17 |
東洋紡株式会社 |
核酸の生成および増幅
|
|
WO2020214642A1
(en)
|
2019-04-19 |
2020-10-22 |
Becton, Dickinson And Company |
Methods of associating phenotypical data and single cell sequencing data
|
|
CN112011833B
(zh)
*
|
2019-05-30 |
2024-04-26 |
上海桀蒙生物技术有限公司 |
筛选和分离肿瘤新生抗原的方法
|
|
IL288283B2
(en)
|
2019-05-30 |
2025-05-01 |
Gritstone Bio Inc |
Modified adenovirus
|
|
US11939622B2
(en)
|
2019-07-22 |
2024-03-26 |
Becton, Dickinson And Company |
Single cell chromatin immunoprecipitation sequencing assay
|
|
CN110277135B
(zh)
*
|
2019-08-10 |
2021-06-01 |
杭州新范式生物医药科技有限公司 |
一种基于预期疗效选择个体化肿瘤新抗原的方法和系统
|
|
EP4031562A4
(en)
*
|
2019-09-20 |
2023-11-01 |
University of Florida Research Foundation, Incorporated |
DETECTION OF ANTIBODIES AGAINST RAN PROTEINS FROM SERUM AND TISSUE LYSATES
|
|
WO2021055973A2
(en)
*
|
2019-09-20 |
2021-03-25 |
Navi Bio-Therapeutics, Inc. |
Personalized cancer immunotherapy
|
|
US12394502B2
(en)
|
2019-10-02 |
2025-08-19 |
The General Hospital Corporation |
Method for predicting HLA-binding peptides using protein structural features
|
|
EP4055610A4
(en)
|
2019-11-05 |
2023-11-29 |
Personalis, Inc. |
ESTIMATION OF TUMOR PURITY FROM SINGLE SAMPLES
|
|
JP7522189B2
(ja)
|
2019-11-08 |
2024-07-24 |
ベクトン・ディキンソン・アンド・カンパニー |
免疫レパートリーシーケンシングのための完全長v(d)j情報を得るためのランダムプライミングの使用
|
|
CN112795647B
(zh)
*
|
2019-11-14 |
2022-08-16 |
北京肿瘤医院(北京大学肿瘤医院) |
一种肿瘤标志物及其应用
|
|
AR120741A1
(es)
|
2019-12-13 |
2022-03-16 |
Genentech Inc |
Anticuerpos anti-ly6g6d y métodos de uso
|
|
WO2021146207A1
(en)
|
2020-01-13 |
2021-07-22 |
Becton, Dickinson And Company |
Methods and compositions for quantitation of proteins and rna
|
|
ES2993319T3
(en)
|
2020-01-29 |
2024-12-27 |
Becton Dickinson Co |
Barcoded wells for spatial mapping of single cells through sequencing
|
|
CN115151810A
(zh)
|
2020-02-25 |
2022-10-04 |
贝克顿迪金森公司 |
实现使用单细胞样品作为单色补偿对照的双特异性探针
|
|
WO2021184017A1
(en)
|
2020-03-13 |
2021-09-16 |
Codiak Biosciences, Inc. |
Extracellular vesicles for treating neurological disorders
|
|
JP2023518414A
(ja)
|
2020-03-20 |
2023-05-01 |
コディアック バイオサイエンシーズ, インコーポレイテッド |
治療のための細胞外小胞
|
|
US11920202B2
(en)
|
2020-04-09 |
2024-03-05 |
University Of Connecticut |
Unbiased identification of tumor rejection mediating neoepitopes
|
|
CN115605614A
(zh)
|
2020-05-14 |
2023-01-13 |
贝克顿迪金森公司(Us) |
用于免疫组库谱分析的引物
|
|
CA3185387A1
(en)
|
2020-05-26 |
2021-12-02 |
Dionis Therapeutics, Inc. |
Nucleic acid artificial mini-proteome libraries
|
|
CN115803445A
(zh)
|
2020-06-02 |
2023-03-14 |
贝克顿迪金森公司 |
用于5撇基因表达测定的寡核苷酸和珠
|
|
US11932901B2
(en)
|
2020-07-13 |
2024-03-19 |
Becton, Dickinson And Company |
Target enrichment using nucleic acid probes for scRNAseq
|
|
WO2022026909A1
(en)
|
2020-07-31 |
2022-02-03 |
Becton, Dickinson And Company |
Single cell assay for transposase-accessible chromatin
|
|
IL300026A
(en)
|
2020-08-06 |
2023-03-01 |
Gritstone Bio Inc |
Multiepitope vaccine cassettes
|
|
EP4196612A1
(en)
|
2020-08-12 |
2023-06-21 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
|
JP2023539332A
(ja)
*
|
2020-08-31 |
2023-09-13 |
ワールド バイオテック リジェネラティブ メディカル グループ リミテッド |
個別化された免疫原性組成物及びその製造方法及びその使用
|
|
EP4216993A2
(en)
|
2020-09-23 |
2023-08-02 |
Codiak BioSciences, Inc. |
Methods of producing extracellular vesicles
|
|
WO2022109343A1
(en)
|
2020-11-20 |
2022-05-27 |
Becton, Dickinson And Company |
Profiling of highly expressed and lowly expressed proteins
|
|
US11161892B1
(en)
|
2020-12-07 |
2021-11-02 |
Think Therapeutics, Inc. |
Method of compact peptide vaccines using residue optimization
|
|
US11421015B2
(en)
|
2020-12-07 |
2022-08-23 |
Think Therapeutics, Inc. |
Method of compact peptide vaccines using residue optimization
|
|
CN116710115A
(zh)
|
2020-11-20 |
2023-09-05 |
思维疗法股份有限公司 |
用于优化的肽疫苗的组合物和方法
|
|
US11058751B1
(en)
|
2020-11-20 |
2021-07-13 |
Think Therapeutics, Inc. |
Compositions for optimized RAS peptide vaccines
|
|
CN117083081A
(zh)
|
2020-12-14 |
2023-11-17 |
百欧恩泰美国公司 |
用于癌症免疫疗法的组织特异性抗原
|
|
US12392771B2
(en)
|
2020-12-15 |
2025-08-19 |
Becton, Dickinson And Company |
Single cell secretome analysis
|
|
US11464842B1
(en)
|
2021-04-28 |
2022-10-11 |
Think Therapeutics, Inc. |
Compositions and method for optimized peptide vaccines using residue optimization
|
|
CN117999355A
(zh)
|
2021-08-24 |
2024-05-07 |
生物技术欧洲股份公司 |
体外转录技术
|
|
US12297508B2
(en)
|
2021-10-05 |
2025-05-13 |
Personalis, Inc. |
Customized assays for personalized cancer monitoring
|
|
WO2023076733A1
(en)
|
2021-11-01 |
2023-05-04 |
Dana-Farber Cancer Institute, Inc. |
Biologically selected nucleic acid artificial mini-proteome libraries
|
|
EP4431603A4
(en)
|
2021-11-10 |
2025-10-29 |
Toyo Boseki |
IMPROVED BANK PREPARATION METHOD
|
|
CN114181287B
(zh)
*
|
2021-12-10 |
2023-09-19 |
商丘美兰生物工程有限公司 |
一种dna病毒疫苗的制备方法
|
|
CN114410778B
(zh)
*
|
2021-12-29 |
2024-03-19 |
中南大学湘雅医院 |
Pf543在制备pd-l1/pd-1单抗肿瘤免疫治疗药物中的应用
|
|
CN114350800B
(zh)
*
|
2021-12-29 |
2024-03-19 |
中南大学湘雅医院 |
Sphk1在制备pd-l1/pd-1单抗肿瘤免疫治疗药物中的应用
|
|
KR20230130804A
(ko)
*
|
2022-03-04 |
2023-09-12 |
(주)큐리진 |
순환종양세포 검출을 위한 아데노바이러스 5/3 형
|
|
EP4253550A1
(en)
|
2022-04-01 |
2023-10-04 |
GenCC GmbH 6 Co. KG |
Method for the manufacture of a viral system, a vector system or any transport system for cancer-specific crispr complexes
|
|
WO2023209068A1
(en)
|
2022-04-28 |
2023-11-02 |
Carbocalyx Gmbh |
Personalized anticancer vaccine comprising glycoengineered tumour cells or tumour cell fragments
|
|
WO2024015892A1
(en)
|
2022-07-13 |
2024-01-18 |
The Broad Institute, Inc. |
Hla-ii immunopeptidome methods and systems for antigen discovery
|
|
IL319414A
(en)
*
|
2022-09-23 |
2025-05-01 |
BioNTech SE |
Compositions for delivering antigens at the liver level and related methods
|
|
WO2024063788A1
(en)
*
|
2022-09-23 |
2024-03-28 |
BioNTech SE |
Compositions for delivery of malaria antigens and related methods
|
|
WO2024083345A1
(en)
|
2022-10-21 |
2024-04-25 |
BioNTech SE |
Methods and uses associated with liquid compositions
|
|
EP4656735A1
(en)
|
2023-01-26 |
2025-12-03 |
Toyobo Co., Ltd. |
Inibhition of reverse transcription derived from ribosomal rna
|
|
WO2025024337A1
(en)
*
|
2023-07-24 |
2025-01-30 |
BioNTech SE |
Compositions for delivery of plasmodium antigens and related methods
|
|
WO2025064850A1
(en)
*
|
2023-09-22 |
2025-03-27 |
BioNTech SE |
Rna constructs with n-terminal degrons to enhance an immune response
|
|
WO2025097055A2
(en)
|
2023-11-02 |
2025-05-08 |
The Broad Institute, Inc. |
Compositions and methods of use of t cells in immunotherapy
|
|
WO2025146078A1
(en)
*
|
2024-01-04 |
2025-07-10 |
Everest Medicines (China) Co., Ltd. |
Cancer vaccines and uses thereof
|
|
US20250335785A1
(en)
|
2024-03-11 |
2025-10-30 |
Instadeep Ltd |
Systems and methods for machine learning-based genome annotation
|
|
WO2025202937A1
(en)
|
2024-03-26 |
2025-10-02 |
BioNTech SE |
Cancer vaccines
|
|
WO2025207807A1
(en)
*
|
2024-03-27 |
2025-10-02 |
The University Of Florida Research Foundation, Inc. |
Ctc rna-loaded nanoparticles and use thereof for the treatment of cancer
|
|
WO2025257735A1
(en)
|
2024-06-10 |
2025-12-18 |
BioNTech SE |
Systems and methods for machine learning model-based prediction of immune response
|
|
CN119049567B
(zh)
*
|
2024-08-08 |
2025-07-22 |
笙源生命科技(安吉)有限公司 |
一种基于单细胞测序区分嵌合体动物模型中异种杂交样本遗传物质和细胞物种来源的方法
|