JP2015529629A5 - - Google Patents
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- Publication number
- JP2015529629A5 JP2015529629A5 JP2015501988A JP2015501988A JP2015529629A5 JP 2015529629 A5 JP2015529629 A5 JP 2015529629A5 JP 2015501988 A JP2015501988 A JP 2015501988A JP 2015501988 A JP2015501988 A JP 2015501988A JP 2015529629 A5 JP2015529629 A5 JP 2015529629A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- amino acid
- cells
- apc
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 108090000765 processed proteins & peptides Proteins 0.000 claims 24
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 11
- 125000003275 alpha amino acid group Chemical group 0.000 claims 10
- 239000012634 fragment Substances 0.000 claims 9
- 210000000447 Th1 cell Anatomy 0.000 claims 7
- 230000001939 inductive effect Effects 0.000 claims 6
- 102000040430 polynucleotide Human genes 0.000 claims 6
- 108091033319 polynucleotide Proteins 0.000 claims 6
- 239000002157 polynucleotide Substances 0.000 claims 6
- 210000001744 T-lymphocyte Anatomy 0.000 claims 5
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims 5
- 238000000034 method Methods 0.000 claims 5
- 108010027412 Histocompatibility Antigens Class II Proteins 0.000 claims 4
- 102000018713 Histocompatibility Antigens Class II Human genes 0.000 claims 4
- 108091008874 T cell receptors Proteins 0.000 claims 4
- 102000016266 T-Cell Antigen Receptors Human genes 0.000 claims 4
- 150000001413 amino acids Chemical class 0.000 claims 4
- 102000004196 processed proteins & peptides Human genes 0.000 claims 4
- 102000043131 MHC class II family Human genes 0.000 claims 3
- 108091054438 MHC class II family Proteins 0.000 claims 3
- 206010028980 Neoplasm Diseases 0.000 claims 3
- 201000011510 cancer Diseases 0.000 claims 3
- 238000012258 culturing Methods 0.000 claims 3
- 238000000338 in vitro Methods 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 108010064366 HLA-DPw2 antigen Proteins 0.000 claims 2
- 108010063970 HLA-DR15 antigen Proteins 0.000 claims 2
- 108010046732 HLA-DR4 Antigen Proteins 0.000 claims 2
- 108010029172 HLA-DR9 antigen Proteins 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 101000590482 Homo sapiens Kinetochore protein Nuf2 Proteins 0.000 claims 1
- 102100032431 Kinetochore protein Nuf2 Human genes 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 230000002980 postoperative effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261669971P | 2012-07-10 | 2012-07-10 | |
| US61/669,971 | 2012-07-10 | ||
| PCT/JP2013/004244 WO2014010229A1 (en) | 2012-07-10 | 2013-07-09 | Cdca1 epitope peptides for th1 cells and vaccines containing the same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015529629A JP2015529629A (ja) | 2015-10-08 |
| JP2015529629A5 true JP2015529629A5 (cg-RX-API-DMAC7.html) | 2016-06-16 |
| JP6255593B2 JP6255593B2 (ja) | 2018-01-10 |
Family
ID=49915710
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015501988A Expired - Fee Related JP6255593B2 (ja) | 2012-07-10 | 2013-07-09 | Ｔｈ１細胞のＣＤＣＡ１エピトープペプチドおよびこれを含有するワクチン |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US9687538B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2872532A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6255593B2 (cg-RX-API-DMAC7.html) |
| TW (2) | TWI627183B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2014010229A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI526219B (zh) * | 2008-06-19 | 2016-03-21 | 腫瘤療法 科學股份有限公司 | Ｃｄｃａ１抗原決定位胜肽及含此胜肽的疫苗 |
| US20150323547A1 (en) * | 2014-03-14 | 2015-11-12 | Brian J. Czerniecki | Methods for monitoring cd4+ t-helper type 1 response in cancer and immune restoration |
| SG11201700839SA (en) * | 2014-08-04 | 2017-03-30 | Oncotherapy Science Inc | Cdca1-derived peptide and vaccine containing same |
| CN107533065A (zh) * | 2015-03-13 | 2018-01-02 | 布莱恩·J·赫尔尼奇 | 在癌症和免疫恢复中监测cd4+1型t辅助细胞应答的方法 |
| TW202023581A (zh) * | 2018-08-02 | 2020-07-01 | 日商腫瘤療法 科學股份有限公司 | 來自cdca1的胜肽及含有此的疫苗 |
| CN117843735B (zh) * | 2023-09-04 | 2025-06-10 | 中国人民解放军海军军医大学 | 新型冠状病毒s1全蛋白组筛选的特异性cd4t细胞表位肽及应用 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002516572A (ja) * | 1997-05-23 | 2002-06-04 | バイオジェン，インコーポレイテッド | 組織の再生の調節 |
| US6800744B1 (en) | 1997-07-02 | 2004-10-05 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
| US7157091B1 (en) | 1999-06-18 | 2007-01-02 | Ludwig Institute For Cancer Research | MAGE-A1 peptides presented by HLA class II molecules |
| US20030211510A1 (en) | 1999-06-30 | 2003-11-13 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
| US6858204B2 (en) | 1999-06-30 | 2005-02-22 | Corxia Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
| US20030170255A1 (en) | 1999-06-30 | 2003-09-11 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
| WO2001022920A2 (en) | 1999-09-29 | 2001-04-05 | Human Genome Sciences, Inc. | Colon and colon cancer associated polynucleotides and polypeptides |
| US7026443B1 (en) | 1999-12-10 | 2006-04-11 | Epimmune Inc. | Inducing cellular immune responses to human Papillomavirus using peptide and nucleic acid compositions |
| JP2003532419A (ja) * | 2000-05-05 | 2003-11-05 | インサイト・ゲノミックス・インコーポレイテッド | 細胞骨格結合タンパク質 |
| AU2002218770A1 (en) * | 2000-07-11 | 2002-01-21 | Corixa Corporaton | Compositions and methods for the therapy and diagnosis of lung cancer |
| US7214786B2 (en) | 2000-12-14 | 2007-05-08 | Kovalic David K | Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement |
| US6867283B2 (en) | 2001-05-16 | 2005-03-15 | Technion Research & Development Foundation Ltd. | Peptides capable of binding to MHC molecules, cells presenting such peptides, and pharmaceutical compositions comprising such peptides and/or cells |
| US20060088825A1 (en) | 2001-09-17 | 2006-04-27 | Ian Hayes | Human delta-n p73 molecules and uses thereof |
| US7892559B2 (en) | 2002-01-30 | 2011-02-22 | Survac Aps | Survivin-derived peptides and use thereof |
| EP2267021B1 (en) | 2002-09-12 | 2015-02-18 | Oncotherapy Science, Inc. | KDR peptides and vaccines comprising the same |
| TW200413725A (en) | 2002-09-30 | 2004-08-01 | Oncotherapy Science Inc | Method for diagnosing non-small cell lung cancers |
| WO2004080148A2 (en) | 2002-10-02 | 2004-09-23 | Nuvelo, Inc. | Novel nucleic acids and polypeptides |
| TW200512298A (en) | 2003-09-24 | 2005-04-01 | Oncotherapy Science Inc | Method of diagnosing breast cancer |
| EP1730534A2 (en) | 2004-03-24 | 2006-12-13 | Oncotherapy Science, Inc. | Compositions and methods for treating lung cancer |
| WO2006085684A2 (en) | 2005-02-10 | 2006-08-17 | Oncotherapy Science, Inc. | Method of diagnosing bladder cancer |
| US8088976B2 (en) * | 2005-02-24 | 2012-01-03 | Monsanto Technology Llc | Methods for genetic control of plant pest infestation and compositions thereof |
| EP1907582B1 (en) | 2005-07-27 | 2012-01-04 | Oncotherapy Science, Inc. | Ect2 as a therapeutic target for esophageal cancer |
| JP2009502115A (ja) | 2005-07-27 | 2009-01-29 | オンコセラピー・サイエンス株式会社 | 小細胞肺癌の診断方法 |
| US7943295B2 (en) | 2005-07-29 | 2011-05-17 | Oncotherapy Science, Inc. | Screening and therapeutic method for NSCLC targeting CDCA1-KNTC2 complex |
| US7776341B2 (en) | 2006-08-10 | 2010-08-17 | Colorado State University Research Foundation | Biomarkers of tuberculosis that distinguish disease categories: use as serodiagnostic antigens |
| RU2486195C2 (ru) * | 2007-08-20 | 2013-06-27 | Онкотерапи Сайенс, Инк. | Пептид cdca1 и включающее его фармацевтическое средство |
| TWI526219B (zh) * | 2008-06-19 | 2016-03-21 | 腫瘤療法 科學股份有限公司 | Ｃｄｃａ１抗原決定位胜肽及含此胜肽的疫苗 |
| GB201004551D0 (en) * | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer |
| GB201004575D0 (en) * | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | Composition of tumor associated peptides and related anti cancer vaccine for the treatment of gastric cancer and other cancers |
| EP2771349B1 (en) * | 2011-09-16 | 2020-02-26 | Iogenetics, LLC. | Bioinformatic processes for determination of peptide binding |
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2013
- 2013-07-09 JP JP2015501988A patent/JP6255593B2/ja not_active Expired - Fee Related
- 2013-07-09 US US14/413,413 patent/US9687538B2/en not_active Expired - Fee Related
- 2013-07-09 EP EP13817533.6A patent/EP2872532A4/en not_active Withdrawn
- 2013-07-09 WO PCT/JP2013/004244 patent/WO2014010229A1/en not_active Ceased
- 2013-07-10 TW TW106112532A patent/TWI627183B/zh not_active IP Right Cessation
- 2013-07-10 TW TW102124658A patent/TWI624475B/zh not_active IP Right Cessation
-
2017
- 2017-01-20 US US15/411,115 patent/US10206989B2/en not_active Expired - Fee Related