JP2014516036A5 - - Google Patents
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- JP2014516036A5 JP2014516036A5 JP2014511553A JP2014511553A JP2014516036A5 JP 2014516036 A5 JP2014516036 A5 JP 2014516036A5 JP 2014511553 A JP2014511553 A JP 2014511553A JP 2014511553 A JP2014511553 A JP 2014511553A JP 2014516036 A5 JP2014516036 A5 JP 2014516036A5
- Authority
- JP
- Japan
- Prior art keywords
- beta
- acid
- phe
- peptide product
- tic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161487636P | 2011-05-18 | 2011-05-18 | |
| US201161487638P | 2011-05-18 | 2011-05-18 | |
| US61/487,638 | 2011-05-18 | ||
| US61/487,636 | 2011-05-18 | ||
| US201161543725P | 2011-10-05 | 2011-10-05 | |
| US201161543721P | 2011-10-05 | 2011-10-05 | |
| US61/543,721 | 2011-10-05 | ||
| US61/543,725 | 2011-10-05 | ||
| PCT/US2012/038429 WO2012158962A2 (en) | 2011-05-18 | 2012-05-17 | Improved peptide pharmaceuticals |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017008902A Division JP6883912B2 (ja) | 2011-05-18 | 2017-01-20 | 改善されたペプチド製剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014516036A JP2014516036A (ja) | 2014-07-07 |
| JP2014516036A5 true JP2014516036A5 (enExample) | 2015-07-09 |
| JP6148228B2 JP6148228B2 (ja) | 2017-06-14 |
Family
ID=47177640
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014511553A Active JP6148228B2 (ja) | 2011-05-18 | 2012-05-17 | 改善されたペプチド製剤 |
| JP2017008902A Active JP6883912B2 (ja) | 2011-05-18 | 2017-01-20 | 改善されたペプチド製剤 |
| JP2019103108A Active JP6929610B2 (ja) | 2011-05-18 | 2019-05-31 | 改善されたペプチド製剤 |
| JP2020174102A Pending JP2021020925A (ja) | 2011-05-18 | 2020-10-15 | 改善されたペプチド製剤 |
| JP2022177489A Pending JP2023022045A (ja) | 2011-05-18 | 2022-11-04 | 改善されたペプチド製剤 |
| JP2024205047A Pending JP2025043342A (ja) | 2011-05-18 | 2024-11-25 | 改善されたペプチド製剤 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017008902A Active JP6883912B2 (ja) | 2011-05-18 | 2017-01-20 | 改善されたペプチド製剤 |
| JP2019103108A Active JP6929610B2 (ja) | 2011-05-18 | 2019-05-31 | 改善されたペプチド製剤 |
| JP2020174102A Pending JP2021020925A (ja) | 2011-05-18 | 2020-10-15 | 改善されたペプチド製剤 |
| JP2022177489A Pending JP2023022045A (ja) | 2011-05-18 | 2022-11-04 | 改善されたペプチド製剤 |
| JP2024205047A Pending JP2025043342A (ja) | 2011-05-18 | 2024-11-25 | 改善されたペプチド製剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US10010617B2 (enExample) |
| EP (3) | EP2709645B1 (enExample) |
| JP (6) | JP6148228B2 (enExample) |
| KR (2) | KR102512178B1 (enExample) |
| CN (2) | CN103796666B (enExample) |
| AU (4) | AU2012255116B2 (enExample) |
| CA (1) | CA2836573C (enExample) |
| WO (2) | WO2012158964A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012255116B2 (en) | 2011-05-18 | 2017-05-25 | Mederis Diabetes, Llc | Improved peptide pharmaceuticals |
| KR102011924B1 (ko) | 2011-05-18 | 2019-08-21 | 메더리스 다이어비티즈, 엘엘씨 | 인슐린 저항성에 대한 개선된 펩티드 제약 |
| MY167234A (en) | 2011-09-23 | 2018-08-14 | Novo Nordisk As | Novel glucagon analogues |
| KR20220051197A (ko) | 2012-05-17 | 2022-04-26 | 익스텐드 바이오사이언시즈, 인크. | 개선된 약물 전달용 캐리어 |
| EP3444281B1 (en) * | 2012-11-20 | 2021-11-03 | Eumederis Pharmaceuticals, Inc. | Improved peptide pharmaceuticals |
| JP6525456B2 (ja) | 2012-11-20 | 2019-06-05 | メデリス ダイアビーティーズ,エルエルシー | インスリン抵抗性のための改善されたペプチド製剤 |
| MY174727A (en) | 2013-04-18 | 2020-05-11 | Novo Nordisk As | Stable, protracted glp-1/glucagon receptor co-agonists for medical use |
| PT3155017T (pt) | 2014-05-28 | 2024-05-14 | Mederis Diabetes Llc | Farmacêuticos peptídicos melhorados para resistência à insulina |
| US10570184B2 (en) | 2014-06-04 | 2020-02-25 | Novo Nordisk A/S | GLP-1/glucagon receptor co-agonists for medical use |
| JP2017532292A (ja) | 2014-08-11 | 2017-11-02 | オルバニー メディカル カレッジ | ミリストイル化レプチン関連ペプチド及びその使用 |
| WO2016065052A1 (en) | 2014-10-22 | 2016-04-28 | Extend Biosciences, Inc. | Insulin vitamin d conjugates |
| US9585934B2 (en) | 2014-10-22 | 2017-03-07 | Extend Biosciences, Inc. | Therapeutic vitamin D conjugates |
| US9789197B2 (en) | 2014-10-22 | 2017-10-17 | Extend Biosciences, Inc. | RNAi vitamin D conjugates |
| JP2020514407A (ja) | 2017-01-24 | 2020-05-21 | マクリーゲン, インク.Macregen, Inc. | アポリポプロテイン模倣物を用いる加齢黄斑変性と他の眼疾患の治療 |
| EP3570888A1 (en) | 2017-03-03 | 2019-11-27 | MacRegen, Inc. | Treatment of age-related macular degeneration and other eye diseases with one or more therapeutic agents |
| US11512111B2 (en) * | 2017-11-27 | 2022-11-29 | The University Of Hong Kong | Yeats inhibitors and methods of use thereof |
| FI3735295T3 (fi) * | 2018-01-03 | 2024-11-20 | Mederis Diabetes Llc | Parannetut peptidilääkkeet nashin ja muiden sairauksien hoitoon |
| MX2020007410A (es) | 2018-01-23 | 2020-11-09 | Gila Therapeutics Inc | Formulaciones, composiciones y métodos farmacéuticos de péptido yy. |
| TWI764248B (zh) * | 2019-08-23 | 2022-05-11 | 大陸商四川海思科製藥有限公司 | 肽醯胺類組合物及其製備 |
| JP7752619B2 (ja) * | 2020-02-21 | 2025-10-10 | スピットファイア ファーマ エルエルシー | Glp-1rおよびgcgrアゴニスト、製剤、ならびに使用方法 |
| US12171806B2 (en) | 2021-09-28 | 2024-12-24 | Spitfire Pharma Llc | Therapeutic regimens and methods for lowering blood glucose and/or body weight using GLP-1R and GCGR balanced agonists |
| WO2022270482A1 (ja) * | 2021-06-24 | 2022-12-29 | 国立大学法人茨城大学 | 糖鎖固定化ポリマー粒子及びその製造方法 |
| KR102844771B1 (ko) * | 2022-07-22 | 2025-08-12 | 주식회사 아이큐어비앤피 | 테리파라타이드를 포함하는 골다공증 예방 또는 치료를 위한 경구용 약학적 조성물 및 이의 제조방법 |
| EP4593867A2 (en) | 2022-09-30 | 2025-08-06 | Extend Biosciences, Inc. | Long-acting parathyroid hormone |
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| FR18245E (fr) | 1913-01-10 | 1914-02-28 | Gedeon Guibal | Flotteur avec index indicateur de niveau, pour chaudières à vapeur et autres appareils, permettant de connaitre le niveau d'un liquide quelconque à une hauteur inférieur au niveau lui-meme |
| US3219656A (en) | 1963-08-12 | 1965-11-23 | Rohm & Haas | Alkylpolyalkoxyalkyl glucosides and process of preparation therefor |
| US3839318A (en) | 1970-09-27 | 1974-10-01 | Rohm & Haas | Process for preparation of alkyl glucosides and alkyl oligosaccharides |
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| JPS6023084B2 (ja) | 1979-07-11 | 1985-06-05 | 味の素株式会社 | 代用血液 |
| US4675189A (en) | 1980-11-18 | 1987-06-23 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble active polypeptides |
| US4640835A (en) | 1981-10-30 | 1987-02-03 | Nippon Chemiphar Company, Ltd. | Plasminogen activator derivatives |
| DE3378121D1 (de) * | 1982-10-18 | 1988-11-03 | Ici Plc | Peptide and pseudopeptide derivatives |
| US4496689A (en) | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
| DK149776C (da) | 1984-01-06 | 1987-04-21 | Orion Yhtymae Oy | Antibiotisk virksom erytromycinforbindelse og praeparat indeholdende forbindelsen |
| AT382381B (de) | 1984-10-02 | 1987-02-25 | Oesterr Zuckerfab Evidenz | Verfahren zur herstellung neuer grenzfl|chenaktiver kohlenhydrat-derivate |
| DE3675588D1 (de) | 1985-06-19 | 1990-12-20 | Ajinomoto Kk | Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist. |
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| JPS63152393A (ja) * | 1986-07-03 | 1988-06-24 | Takeda Chem Ind Ltd | グリコシル誘導体 |
| US5252318A (en) | 1990-06-15 | 1993-10-12 | Allergan, Inc. | Reversible gelation compositions and methods of use |
| US5589452A (en) * | 1992-07-14 | 1996-12-31 | Syntex (U.S.A.) Inc. | Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis |
| US5661130A (en) | 1993-06-24 | 1997-08-26 | The Uab Research Foundation | Absorption enhancers for drug administration |
| SE9401596D0 (sv) * | 1994-05-06 | 1994-05-06 | Astra Ab | New compounds |
| JPH1160598A (ja) | 1997-08-15 | 1999-03-02 | Asahi Glass Co Ltd | オピオイド様ペプチド |
| US20010010919A1 (en) * | 1998-10-13 | 2001-08-02 | David K. Grandy | Opioid antagonists and methods of their use |
| US6924264B1 (en) | 1999-04-30 | 2005-08-02 | Amylin Pharmaceuticals, Inc. | Modified exendins and exendin agonists |
| US6309633B1 (en) * | 1999-06-19 | 2001-10-30 | Nobex Corporation | Amphiphilic drug-oligomer conjugates with hydroyzable lipophile components and methods for making and using the same |
| RU2181729C1 (ru) * | 2000-09-20 | 2002-04-27 | Калюжин Олег Витальевич | Производные мурамовой кислоты |
| US6835802B2 (en) | 2001-06-04 | 2004-12-28 | Nobex Corporation | Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties |
| US6858580B2 (en) | 2001-06-04 | 2005-02-22 | Nobex Corporation | Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same |
| US6864069B2 (en) | 2001-10-05 | 2005-03-08 | Bayer Pharmaceuticals Corporation | Peptides acting as both GLP-1 receptor agonists and glucagon receptor antagonists and their pharmacological methods of use |
| EP2042196B1 (en) | 2001-10-10 | 2016-07-13 | ratiopharm GmbH | Remodelling and glycoconjugation of Granulocyte Colony Stimulating Factor (G-CSF) |
| US20050255038A1 (en) * | 2002-04-12 | 2005-11-17 | A And D Bioscience, Inc. | Conjugates comprising cancer cell specific ligands, a sugar and diagnostic agents and uses thereof |
| US6881829B2 (en) * | 2002-04-26 | 2005-04-19 | Chimeracom, L.L.C. | Chimeric hybrid analgesics |
| WO2004093902A1 (en) * | 2003-03-19 | 2004-11-04 | The General Hospital Corporation | CONFORMATIONALLY CONSTRAINED PARATHYROID HORMONES WITH α-HELIX STABILIZERS |
| US20060046962A1 (en) | 2004-08-25 | 2006-03-02 | Aegis Therapeutics Llc | Absorption enhancers for drug administration |
| US20110257096A1 (en) | 2004-08-25 | 2011-10-20 | Aegis Therapeutics, Inc. | Compositions for drug administration |
| ITRM20040607A1 (it) * | 2004-12-15 | 2005-03-15 | Biogen S R L | Analoghi della dermorfina ad attivita' analgesica. |
| US7776819B2 (en) * | 2005-03-03 | 2010-08-17 | The Board Of Trustees Of The University Of Illinois | Targeted drug delivery of pain and addiction therapies using opioid receptor-mediated internalization |
| JP2008539735A (ja) | 2005-05-06 | 2008-11-20 | バイエル・フアーマシユーチカルズ・コーポレーシヨン | グルカゴン様ペプチド1(glp−1)受容体アンタゴニストおよびそれらの薬理学的使用方法 |
| WO2007002465A2 (en) | 2005-06-23 | 2007-01-04 | Rapid Pharmaceuticals, Llc | Stabilizing alkylglycoside compositions and methods thereof |
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| CN101784281B (zh) * | 2007-08-01 | 2014-07-02 | 总医院有限公司 | 确定g蛋白偶联受体激动剂的方法 |
| EP2052736A1 (en) * | 2007-10-26 | 2009-04-29 | Nycomed Danmark ApS | Parathyroid hormone formulations und uses thereof |
| EP2300037B1 (en) | 2008-06-17 | 2016-03-30 | Indiana University Research and Technology Corporation | Glucagon/glp-1 receptor co-agonists |
| AU2012255116B2 (en) | 2011-05-18 | 2017-05-25 | Mederis Diabetes, Llc | Improved peptide pharmaceuticals |
| KR102011924B1 (ko) | 2011-05-18 | 2019-08-21 | 메더리스 다이어비티즈, 엘엘씨 | 인슐린 저항성에 대한 개선된 펩티드 제약 |
| EP3444281B1 (en) | 2012-11-20 | 2021-11-03 | Eumederis Pharmaceuticals, Inc. | Improved peptide pharmaceuticals |
| JP6525456B2 (ja) * | 2012-11-20 | 2019-06-05 | メデリス ダイアビーティーズ,エルエルシー | インスリン抵抗性のための改善されたペプチド製剤 |
| PT3155017T (pt) | 2014-05-28 | 2024-05-14 | Mederis Diabetes Llc | Farmacêuticos peptídicos melhorados para resistência à insulina |
| FI3735295T3 (fi) * | 2018-01-03 | 2024-11-20 | Mederis Diabetes Llc | Parannetut peptidilääkkeet nashin ja muiden sairauksien hoitoon |
| JP7752619B2 (ja) * | 2020-02-21 | 2025-10-10 | スピットファイア ファーマ エルエルシー | Glp-1rおよびgcgrアゴニスト、製剤、ならびに使用方法 |
-
2012
- 2012-05-17 AU AU2012255116A patent/AU2012255116B2/en active Active
- 2012-05-17 CN CN201280035528.1A patent/CN103796666B/zh active Active
- 2012-05-17 KR KR1020207017489A patent/KR102512178B1/ko active Active
- 2012-05-17 US US14/118,546 patent/US10010617B2/en active Active
- 2012-05-17 EP EP12784971.9A patent/EP2709645B1/en active Active
- 2012-05-17 CA CA2836573A patent/CA2836573C/en active Active
- 2012-05-17 CN CN201810595590.5A patent/CN108892709A/zh active Pending
- 2012-05-17 EP EP19176297.0A patent/EP3566711A1/en not_active Withdrawn
- 2012-05-17 WO PCT/US2012/038433 patent/WO2012158964A2/en not_active Ceased
- 2012-05-17 EP EP23168618.9A patent/EP4286400A3/en active Pending
- 2012-05-17 JP JP2014511553A patent/JP6148228B2/ja active Active
- 2012-05-17 WO PCT/US2012/038429 patent/WO2012158962A2/en not_active Ceased
- 2012-05-17 KR KR1020137033672A patent/KR102126484B1/ko active Active
-
2017
- 2017-01-20 JP JP2017008902A patent/JP6883912B2/ja active Active
- 2017-08-17 AU AU2017216533A patent/AU2017216533B2/en active Active
-
2018
- 2018-03-06 US US15/913,845 patent/US10420844B2/en active Active
-
2019
- 2019-05-31 JP JP2019103108A patent/JP6929610B2/ja active Active
- 2019-09-23 US US16/579,799 patent/US20210077629A1/en not_active Abandoned
- 2019-12-05 AU AU2019275610A patent/AU2019275610A1/en not_active Abandoned
-
2020
- 2020-03-21 US US16/826,208 patent/US20200289653A1/en active Pending
- 2020-10-15 JP JP2020174102A patent/JP2021020925A/ja active Pending
-
2021
- 2021-11-01 AU AU2021258101A patent/AU2021258101B2/en active Active
-
2022
- 2022-11-04 JP JP2022177489A patent/JP2023022045A/ja active Pending
-
2024
- 2024-11-25 JP JP2024205047A patent/JP2025043342A/ja active Pending
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