JP2014515744A5 - - Google Patents

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JP2014515744A5
JP2014515744A5 JP2014503978A JP2014503978A JP2014515744A5 JP 2014515744 A5 JP2014515744 A5 JP 2014515744A5 JP 2014503978 A JP2014503978 A JP 2014503978A JP 2014503978 A JP2014503978 A JP 2014503978A JP 2014515744 A5 JP2014515744 A5 JP 2014515744A5
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JP
Japan
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calcium channel
microparticle
therapeutic agent
sterile
type voltage
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JP2014503978A
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English (en)
Japanese (ja)
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JP6336899B2 (ja
JP2014515744A (ja
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Priority claimed from PCT/US2012/032317 external-priority patent/WO2012138854A1/en
Publication of JP2014515744A publication Critical patent/JP2014515744A/ja
Publication of JP2014515744A5 publication Critical patent/JP2014515744A5/ja
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Publication of JP6336899B2 publication Critical patent/JP6336899B2/ja
Expired - Fee Related legal-status Critical Current
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JP2014503978A 2011-04-05 2012-04-05 脳血流に影響する脳損傷後の結果を改善するための脳室内ドラッグデリバリーシステム Expired - Fee Related JP6336899B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161471779P 2011-04-05 2011-04-05
US61/471,779 2011-04-05
PCT/US2012/032317 WO2012138854A1 (en) 2011-04-05 2012-04-05 Intraventricular drug delivery system for improving outcome after a brain injury affecting cerebral blood flow

Related Child Applications (1)

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JP2016205897A Division JP2017036320A (ja) 2011-04-05 2016-10-20 脳血流に影響する脳損傷後の結果を改善するための脳室内ドラッグデリバリーシステム

Publications (3)

Publication Number Publication Date
JP2014515744A JP2014515744A (ja) 2014-07-03
JP2014515744A5 true JP2014515744A5 (https=) 2017-01-12
JP6336899B2 JP6336899B2 (ja) 2018-06-06

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JP2014503978A Expired - Fee Related JP6336899B2 (ja) 2011-04-05 2012-04-05 脳血流に影響する脳損傷後の結果を改善するための脳室内ドラッグデリバリーシステム
JP2016205897A Withdrawn JP2017036320A (ja) 2011-04-05 2016-10-20 脳血流に影響する脳損傷後の結果を改善するための脳室内ドラッグデリバリーシステム

Family Applications After (1)

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JP2016205897A Withdrawn JP2017036320A (ja) 2011-04-05 2016-10-20 脳血流に影響する脳損傷後の結果を改善するための脳室内ドラッグデリバリーシステム

Country Status (13)

Country Link
US (2) US9364432B2 (https=)
EP (1) EP2694133B1 (https=)
JP (2) JP6336899B2 (https=)
KR (1) KR20140052992A (https=)
CN (1) CN103517726B (https=)
AU (1) AU2012240131B2 (https=)
CA (1) CA2832501A1 (https=)
GB (1) GB2513675A (https=)
HK (1) HK1198933A1 (https=)
IL (1) IL228539B (https=)
RU (2) RU2606169C2 (https=)
SG (2) SG193991A1 (https=)
WO (1) WO2012138854A1 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10092524B2 (en) * 2008-06-11 2018-10-09 Edge Therapeutics, Inc. Compositions and their use to treat complications of aneurysmal subarachnoid hemorrhage
RU2606169C2 (ru) * 2011-04-05 2017-01-10 Эдж Терапьютикс Система интравентрикулярной доставки лекарственного средства для улучшения исхода после повреждения головного мозга, нарушающего мозговое кровообращение
US9399019B2 (en) 2012-05-09 2016-07-26 Evonik Corporation Polymorph compositions, methods of making, and uses thereof
WO2014027042A2 (en) * 2012-08-17 2014-02-20 Amsilk Gmbh Use of self-assembling polypeptides as tissue adhesives
CN103211812A (zh) * 2013-04-02 2013-07-24 苏州大学附属第一医院 Skf96365在治疗蛛网膜下腔出血后发生的脑血管痉挛的应用
RU2741629C2 (ru) 2016-09-20 2021-01-28 Бракко Дайэгностикс Инк. Системы и способы производства, инфузионного ввода и контроля доставки радиоактивного изотопа
US10646227B2 (en) 2016-12-29 2020-05-12 Cerepeutics, LLC Systems and methods for acute treatment to limit intracerebral hemorrhage growth
WO2019018306A1 (en) * 2017-07-17 2019-01-24 Edge Therapeutics, Inc. ADVANCED MICROPARTICULAR FORMULATIONS CONTAINING FORM 2 OF MICRONIZED POLYMORPHIC NIMODIPINE
US20190060109A1 (en) * 2017-08-31 2019-02-28 Gregory Todd Johnson Method of Preventing Traumatic Brain Injury (TBI)
SG11202009326XA (en) 2018-03-28 2020-10-29 Bracco Diagnostics Inc Early detection of radioisotope generator end life
US12170153B2 (en) 2018-03-28 2024-12-17 Bracco Diagnostics Inc. Systems and techniques for calibrating radioisotope delivery systems with a gamma detector
CN115104159A (zh) 2020-02-21 2022-09-23 布拉科诊断公司 放射性同位素发生器早期突破检测
US12016774B2 (en) 2020-05-08 2024-06-25 Medtronic Vascular, Inc. Delivery system for prosthetic valve device having controlled release of inflow and outflow ends
RU2763254C1 (ru) * 2020-08-31 2021-12-28 Федеральное государственное бюджетное образовательное учреждение высшего образования "Волгоградский государственный медицинский университет" Министерства здравоохранения Российской Федерации ФГБОУ ВО ВолгГМУ МЗ РФ Способ лечения церебрального вазоспазма при аневризматическом субарахноидальном кровоизлиянии
US11992642B2 (en) 2020-10-30 2024-05-28 Medtronic, Inc. Implantable medical device for delivery of pharmacological agents to the deep brain structures
US11931545B2 (en) 2020-10-30 2024-03-19 Medtronic, Inc. Drug infusion port
US11745003B2 (en) 2020-10-30 2023-09-05 Medtronic, Inc. Implantable access port with one-directional filter
US12551613B2 (en) 2020-10-30 2026-02-17 Medtronic, Inc. Implantable drug delivery port
US12226609B2 (en) 2020-12-16 2025-02-18 Medtronic, Inc. Method to detect inadvertent delivery of drug to a subcutaneous pocket

Family Cites Families (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4757128A (en) 1986-08-01 1988-07-12 Massachusetts Institute Of Technology High molecular weight polyanhydride and preparation thereof
DK0471036T4 (da) 1989-05-04 2004-07-19 Southern Res Inst Indkapslingsfremgangsmåde
US5650489A (en) 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
IT1243390B (it) 1990-11-22 1994-06-10 Vectorpharma Int Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione.
US5399665A (en) 1992-11-05 1995-03-21 Massachusetts Institute Of Technology Biodegradable polymers for cell transplantation
AU704183B2 (en) 1994-01-05 1999-04-15 Arqule, Inc. Systematic modular production of aminimide- and oxazolone-based molecules having selected properties
US5712171A (en) 1995-01-20 1998-01-27 Arqule, Inc. Method of generating a plurality of chemical compounds in a spatially arranged array
US5968542A (en) 1995-06-07 1999-10-19 Southern Biosystems, Inc. High viscosity liquid controlled delivery system as a device
US5747058A (en) 1995-06-07 1998-05-05 Southern Biosystems, Inc. High viscosity liquid controlled delivery system
AT404429B (de) 1995-06-09 1998-11-25 Immuno Ag Anti-plasma-antikörper-präparation
JP2909418B2 (ja) * 1995-09-18 1999-06-23 株式会社資生堂 薬物の遅延放出型マイクロスフイア
CN1304058C (zh) 1996-03-12 2007-03-14 Pg－Txl有限公司 水溶性紫杉醇产品
JP4642946B2 (ja) * 1996-12-20 2011-03-02 アルザ コーポレイション ゲル組成物および方法
US6123956A (en) * 1997-07-10 2000-09-26 Keith Baker Methods for universally distributing therapeutic agents to the brain
US6358536B1 (en) * 1997-10-15 2002-03-19 Thomas Jefferson University Nitric oxide donor compositions, methods, apparatus, and kits for preventing or alleviating vasoconstriction or vasospasm in a mammal
JP2000070366A (ja) * 1998-09-02 2000-03-07 Arute:Kk 容器兼用注射器及び容器兼用注射器への凍結乾燥製剤の封入方法
CA2396016A1 (en) * 1999-12-29 2001-07-05 Andy Bernhardt System for reconstituting pastes and methods of using same
JP2003520830A (ja) 2000-01-25 2003-07-08 エドワーズ ライフサイエンシーズ コーポレイション 再狭窄および吻合内膜過形成処置のための送達系
WO2003020208A2 (en) * 2001-08-31 2003-03-13 Neuron Therapeutics, Inc. Treatment of neurologic hemorrhage
US20040235801A1 (en) 2001-10-25 2004-11-25 Jean-Pierre Julien Therapy for stroke
DE60236686D1 (de) 2001-11-22 2010-07-22 Dainippon Sumitomo Pharma Co Nichtmenschliches tiermodell, das nicht auf eine immunopotenzierende synthetische verbindung anspricht
DE60335608D1 (de) 2002-02-27 2011-02-17 Pharmain Corp Zusammensetzungen zur abgabe von therapeutika und anderen materialien und verfahren zu ihrer herstellung und verwendung
TW200307011A (en) * 2002-04-18 2003-12-01 Chugai Pharmaceutical Co Ltd Hyaluronic acid modifier
WO2003093465A1 (en) 2002-04-30 2003-11-13 Maxygen Holdings Ltd. FACTOR VII OR VIIa POLYPEPTIDE VARIANTS
RU2005102604A (ru) 2002-07-03 2005-09-10 Перикор Сайенс, Инк. (Us) Композиция гиалуроновой кислоты и способы применения
ATE487470T1 (de) 2002-09-11 2010-11-15 Elan Pharma Int Ltd Gel-stabilisierte wirkstoff-zusammensetzungen in nanoteilchengrösse
JP4092994B2 (ja) * 2002-09-13 2008-05-28 ニプロ株式会社 プレフィルドシリンジキット
EP1575562B1 (en) * 2002-11-26 2016-10-05 Seacoast Neurosciene, Inc. Buoyant polymer particles delivering therapeutic agents
US20070207211A1 (en) 2003-04-10 2007-09-06 Pr Pharmaceuticals, Inc. Emulsion-based microparticles and methods for the production thereof
ES2427092T3 (es) 2003-04-10 2013-10-28 Evonik Corporation Un método para la producción de micropartículas a base de emulsión
JP5165240B2 (ja) 2003-07-23 2013-03-21 ピーアール ファーマシューティカルズ， インコーポレイテッド 徐放組成物
US9149440B2 (en) * 2003-09-02 2015-10-06 University Of South Florida Nanoparticles for drug-delivery
WO2006002365A2 (en) * 2004-06-24 2006-01-05 Angiotech International Ag Microparticles with high loadings of a bioactive agent
US20060205733A1 (en) 2004-08-26 2006-09-14 Encysive Pharmaceuticals Endothelin a receptor antagonists in combination with phosphodiesterase 5 inhibitors and uses thereof
US8034762B2 (en) * 2004-09-02 2011-10-11 Cognosci, Inc. Treatment of subarachnoid hemorrhage with Apo E analogs
WO2006084005A2 (en) 2005-02-02 2006-08-10 University Of Vermont And State Agricultural College Emergence of a r-type ca2+channel(cav2.3) contributes to cerebral artery constriction following subarachnoid hemorrhage
EP1858542A4 (en) 2005-02-24 2009-08-19 Joslin Diabetes Center Inc COMPOSITIONS AND METHOD FOR THE TREATMENT OF VASPEREPERMABILITY
US20060217340A1 (en) * 2005-03-23 2006-09-28 University Of Vermont And State Agricultural College Methods and products for treating hypertension by modulation of TRPC3 channel activity
WO2006103112A2 (en) * 2005-03-31 2006-10-05 Lidds Ab Method for treating prostate diseases based on local delivery of active substances
WO2006114105A2 (en) 2005-04-26 2006-11-02 Maxygen Holdings Ltd. Use of modified factor vii for treating bleeding
EP1883465B1 (fr) * 2005-05-24 2010-01-20 Utéron Pharma S.A. Dispositif de melange a double chambre pour substances pharmaceutiques visqueuses et procede
WO2006133045A1 (en) * 2005-06-03 2006-12-14 Elan Pharma International, Limited Nanoparticulate benidipine compositions
US20090156481A1 (en) 2005-07-15 2009-06-18 Novo Nordisk Healthcare A/G Use of Factor VIIa or Factor VIIa Equivalents for Preventing or Attenuating Haemorrhage Growth, and/or Oedema Generation Following Intracerebral Haemorrhage (ICH) in Patients Treated with Antiplatelet Therapy
EP1951262A4 (en) * 2005-11-21 2010-09-15 Univ Alabama METHOD OF USING SMALL-MOLECOLLAR COMPOUNDS FOR NERVE PROTECTION
US9005183B2 (en) * 2007-05-16 2015-04-14 Health Knight, Llc System and method for treating erectile dysfunction
US10092524B2 (en) 2008-06-11 2018-10-09 Edge Therapeutics, Inc. Compositions and their use to treat complications of aneurysmal subarachnoid hemorrhage
WO2008154585A1 (en) * 2007-06-11 2008-12-18 Macdonald R Loch A drug delivery system for the prevention of cerebral vasospasm
WO2009085952A1 (en) 2007-12-20 2009-07-09 Brookwood Pharmaceuticals, Inc. Process for preparing microparticles having a low residual solvent volume
JP2009067771A (ja) * 2008-05-27 2009-04-02 Pacira Pharmaceuticals Inc 神経学的疾患の治療方法
US20100008968A1 (en) 2008-06-26 2010-01-14 Lampe John W Method for treating cardiovascular diseases using rho kinase inhibitor compounds
WO2010030868A1 (en) 2008-09-11 2010-03-18 Surmodics Pharmaceuticals, Inc. Solvent extraction microencapsulation with tunable extraction rates
JP5769626B2 (ja) 2008-09-18 2015-08-26 エボニック コーポレイションＥｖｏｎｉｋ Ｃｏｒｐｏｒａｔｉｏｎ 溶媒および塩を用いるマイクロカプセル封入プロセス
CA2750003A1 (en) 2009-01-23 2010-07-29 Surmodics Pharmaceuticals, Inc. Controlled release systems from polymer blends
US20130059008A1 (en) 2009-01-23 2013-03-07 Jeffrey L. Atkinson Drying methods for tuning microparticle properties
WO2010085608A1 (en) 2009-01-23 2010-07-29 Surmodics Pharmaceuticals, Inc. Polymer mixtures comprising polymers having different non-repeating units and methods for making and using same
US20100291027A1 (en) 2009-05-14 2010-11-18 Jason Campbell Hyaluronic acid (ha) injection vehicle
US20110033463A1 (en) 2009-08-06 2011-02-10 Medtronic, Inc. Apheresis, administration of agent, or combination thereof
CA2784287C (en) 2009-12-22 2017-07-18 Evonik Degussa Corporation Emulsion-based process for preparing microparticles and workhead assembly for use with same
EP2538956A4 (en) 2010-02-22 2015-04-22 Edge Therapeutics Inc METHODS AND COMPOSITIONS FOR TREATING HEMORRHAGIC BRAIN DISORDERS
CA2794328C (en) 2010-03-29 2018-01-16 Evonik Degussa Corporation Compositions and methods for improved retention of a pharmaceutical composition at a local administration site
WO2012102587A2 (ko) * 2011-01-27 2012-08-02 (주)Lg화학 간극 충진용 스웰링 테이프
RU2606169C2 (ru) * 2011-04-05 2017-01-10 Эдж Терапьютикс Система интравентрикулярной доставки лекарственного средства для улучшения исхода после повреждения головного мозга, нарушающего мозговое кровообращение

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