RU2606169C2 - Система интравентрикулярной доставки лекарственного средства для улучшения исхода после повреждения головного мозга, нарушающего мозговое кровообращение - Google Patents

Система интравентрикулярной доставки лекарственного средства для улучшения исхода после повреждения головного мозга, нарушающего мозговое кровообращение Download PDF

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RU2606169C2
RU2606169C2 RU2013148938A RU2013148938A RU2606169C2 RU 2606169 C2 RU2606169 C2 RU 2606169C2 RU 2013148938 A RU2013148938 A RU 2013148938A RU 2013148938 A RU2013148938 A RU 2013148938A RU 2606169 C2 RU2606169 C2 RU 2606169C2
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brain
composition
sterile
cerebral
therapeutic agent
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RU2013148938A (ru
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Р. Лок МАКДОНАЛЬД
Брайан А. ЛЕЙТНЕР
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Эдж Терапьютикс
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • AHUMAN NECESSITIES
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/33Heterocyclic compounds
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/44221,4-Dihydropyridines, e.g. nifedipine, nicardipine
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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RU2013148938A 2011-04-05 2012-04-05 Система интравентрикулярной доставки лекарственного средства для улучшения исхода после повреждения головного мозга, нарушающего мозговое кровообращение RU2606169C2 (ru)

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US201161471779P 2011-04-05 2011-04-05
US61/471,779 2011-04-05
PCT/US2012/032317 WO2012138854A1 (en) 2011-04-05 2012-04-05 Intraventricular drug delivery system for improving outcome after a brain injury affecting cerebral blood flow

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RU2016144847A Division RU2016144847A (ru) 2011-04-05 2016-11-16 Система интравентрикулярной доставки лекарственного средства для улучшения исхода после повреждения головного мозга, нарушающего мозговое кровообращение

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RU2016144847A RU2016144847A (ru) 2011-04-05 2016-11-16 Система интравентрикулярной доставки лекарственного средства для улучшения исхода после повреждения головного мозга, нарушающего мозговое кровообращение

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US (2) US9364432B2 (https=)
EP (1) EP2694133B1 (https=)
JP (2) JP6336899B2 (https=)
KR (1) KR20140052992A (https=)
CN (1) CN103517726B (https=)
AU (1) AU2012240131B2 (https=)
CA (1) CA2832501A1 (https=)
GB (1) GB2513675A (https=)
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US11752254B2 (en) 2016-09-20 2023-09-12 Bracco Diagnostics Inc. Radioisotope delivery system with multiple detectors to detect gamma and beta emissions
US11810685B2 (en) 2018-03-28 2023-11-07 Bracco Diagnostics Inc. Early detection of radioisotope generator end life
US12170153B2 (en) 2018-03-28 2024-12-17 Bracco Diagnostics Inc. Systems and techniques for calibrating radioisotope delivery systems with a gamma detector
US12573516B2 (en) 2020-02-21 2026-03-10 Bracco Diagnostics Inc. Radioisotope generator early breakthrough detection

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US20190060109A1 (en) * 2017-08-31 2019-02-28 Gregory Todd Johnson Method of Preventing Traumatic Brain Injury (TBI)
US12016774B2 (en) 2020-05-08 2024-06-25 Medtronic Vascular, Inc. Delivery system for prosthetic valve device having controlled release of inflow and outflow ends
RU2763254C1 (ru) * 2020-08-31 2021-12-28 Федеральное государственное бюджетное образовательное учреждение высшего образования "Волгоградский государственный медицинский университет" Министерства здравоохранения Российской Федерации ФГБОУ ВО ВолгГМУ МЗ РФ Способ лечения церебрального вазоспазма при аневризматическом субарахноидальном кровоизлиянии
US11992642B2 (en) 2020-10-30 2024-05-28 Medtronic, Inc. Implantable medical device for delivery of pharmacological agents to the deep brain structures
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US11745003B2 (en) 2020-10-30 2023-09-05 Medtronic, Inc. Implantable access port with one-directional filter
US12551613B2 (en) 2020-10-30 2026-02-17 Medtronic, Inc. Implantable drug delivery port
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