JP2014515372A5 - - Google Patents

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Publication number
JP2014515372A5
JP2014515372A5 JP2014512145A JP2014512145A JP2014515372A5 JP 2014515372 A5 JP2014515372 A5 JP 2014515372A5 JP 2014512145 A JP2014512145 A JP 2014512145A JP 2014512145 A JP2014512145 A JP 2014512145A JP 2014515372 A5 JP2014515372 A5 JP 2014515372A5
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JP
Japan
Prior art keywords
crystalline form
cyclosporin
ophthalmically acceptable
crystalline
diffraction pattern
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2014512145A
Other languages
English (en)
Japanese (ja)
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JP2014515372A (ja
JP6163482B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2012/039611 external-priority patent/WO2012166610A1/en
Publication of JP2014515372A publication Critical patent/JP2014515372A/ja
Publication of JP2014515372A5 publication Critical patent/JP2014515372A5/ja
Application granted granted Critical
Publication of JP6163482B2 publication Critical patent/JP6163482B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2014512145A 2011-05-27 2012-05-25 シクロスポリンaの結晶形態、その調製方法、およびその使用のための方法 Expired - Fee Related JP6163482B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161490887P 2011-05-27 2011-05-27
US61/490,887 2011-05-27
PCT/US2012/039611 WO2012166610A1 (en) 2011-05-27 2012-05-25 A crystalline form of cyclosporine a, methods of preparation, and methods for use thereof

Publications (3)

Publication Number Publication Date
JP2014515372A JP2014515372A (ja) 2014-06-30
JP2014515372A5 true JP2014515372A5 (https=) 2015-04-30
JP6163482B2 JP6163482B2 (ja) 2017-07-12

Family

ID=46178866

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014512145A Expired - Fee Related JP6163482B2 (ja) 2011-05-27 2012-05-25 シクロスポリンaの結晶形態、その調製方法、およびその使用のための方法

Country Status (19)

Country Link
US (4) US8772245B2 (https=)
EP (2) EP2714720B1 (https=)
JP (1) JP6163482B2 (https=)
KR (1) KR102079402B1 (https=)
CN (1) CN103649108B (https=)
AR (1) AR086586A1 (https=)
AU (4) AU2012262513B2 (https=)
BR (1) BR112013030554B1 (https=)
CA (1) CA2836946C (https=)
CL (1) CL2013003400A1 (https=)
IL (2) IL229475A0 (https=)
MX (1) MX362271B (https=)
MY (1) MY180581A (https=)
RU (1) RU2602062C2 (https=)
SG (1) SG10201607344UA (https=)
TW (1) TWI554522B (https=)
UA (1) UA113627C2 (https=)
WO (1) WO2012166610A1 (https=)
ZA (1) ZA201308665B (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3701939A1 (en) * 2011-11-15 2020-09-02 Allergan, Inc. Suspensions of cyclosporin a form 2
WO2013074610A1 (en) 2011-11-15 2013-05-23 Allergan, Inc. Sustained action formulation of cyclosporin form 2
BR112014011768A2 (pt) * 2011-11-15 2017-05-09 Allergan Inc forma 2 de ciclosporina a e método de produção da mesma
US20130123194A1 (en) * 2011-11-15 2013-05-16 Allergan, Inc. Autoclavable suspensions of cyclosporin a form 2
JP2015519368A (ja) 2012-06-01 2015-07-09 アラーガン インコーポレイテッドAllergan,Incorporated シクロスポリンa類似体
GB201222455D0 (en) * 2012-12-13 2013-01-30 Perioc Ltd Novel pharmaceutical formulations and their use in the treatment of periodontaldisease
US10524661B2 (en) * 2013-06-12 2020-01-07 Proactive Live, Inc. Sleep monitoring and stimulation
RU2713953C2 (ru) 2014-07-18 2020-02-11 Аллерган, Инк. Суспензионные составы циклоспорина а для субконъюнктивального и периокулярного введения
US9914755B2 (en) 2015-01-08 2018-03-13 Allergan, Inc. Cyclosporin derivatives wherein the MeBmt sidechain has been cyclized
US10443292B2 (en) * 2016-04-25 2019-10-15 Magna Closures, Inc. Non-contact obstacle detection system for motor vehicles
RU2766160C2 (ru) 2017-05-17 2022-02-08 Юю Фарма, Инк. Новый пептид и фармацевтический состав для лечения глазного заболевания, содержащий пептид в качестве активного фармацевтического ингредиента
US11613558B2 (en) 2018-11-14 2023-03-28 Yuyu Pharma, Inc. Peptides and pharmaceutical compositions for treating eye diseases
MX2024002234A (es) * 2021-08-20 2024-04-17 Sun Pharmaceutical Ind Ltd Formulación oftalmológica de ciclosporina estable y proceso de fabricación de esta.
TW202430537A (zh) 2022-10-20 2024-08-01 日商中外製藥股份有限公司 環狀胜肽的結晶的製造方法
WO2024195801A1 (ja) 2023-03-20 2024-09-26 中外製薬株式会社 環状ペプチドの共結晶の製造方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU203564B (en) * 1987-12-21 1991-08-28 Sandoz Ag Process for producing new orthorombos cyclosporin without solvatation
GB9105705D0 (en) * 1991-03-18 1991-05-01 Sandoz Ltd Improvements in or relating to organic compounds
US5474979A (en) 1994-05-17 1995-12-12 Allergan, Inc. Nonirritating emulsions for sensitive tissue
US6254860B1 (en) * 1999-04-13 2001-07-03 Allergan Sales, Inc. Ocular treatment using cyclosporin-A derivatives
US6656504B1 (en) * 1999-09-09 2003-12-02 Elan Pharma International Ltd. Nanoparticulate compositions comprising amorphous cyclosporine and methods of making and using such compositions
RU2009144186A (ru) 2007-05-04 2011-06-10 Аллерган, Инк. (Us) Применение циклоспоринов при лечении пациентов с интраокулярными линзами
US20090286718A1 (en) * 2008-01-04 2009-11-19 Sirion Therapeutics, Inc. Stable Aqueous Cyclosporin Compositions

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