UA113627C2 - Кристалічна форма циклоспорину a, фармацевтична композиція та спосіб лікування - Google Patents

Кристалічна форма циклоспорину a, фармацевтична композиція та спосіб лікування

Info

Publication number
UA113627C2
UA113627C2 UAA201314231A UAA201314231A UA113627C2 UA 113627 C2 UA113627 C2 UA 113627C2 UA A201314231 A UAA201314231 A UA A201314231A UA A201314231 A UAA201314231 A UA A201314231A UA 113627 C2 UA113627 C2 UA 113627C2
Authority
UA
Ukraine
Prior art keywords
cyclosporin
treatment
pharmaceutical composition
crystal form
present
Prior art date
Application number
UAA201314231A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46178866&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA113627(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of UA113627C2 publication Critical patent/UA113627C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C07K1/306—Extraction; Separation; Purification by precipitation by crystallization
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Даний винахід у цілому стосується кристалічних форм циклоспорину А і, зокрема, нещодавно виявленої форми циклоспорину А. Крім того даний винахід стосується способу його одержання й способів лікування певних захворювань очей.
UAA201314231A 2011-05-27 2012-05-25 Кристалічна форма циклоспорину a, фармацевтична композиція та спосіб лікування UA113627C2 (xx)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161490887P 2011-05-27 2011-05-27
PCT/US2012/039611 WO2012166610A1 (en) 2011-05-27 2012-05-25 A crystalline form of cyclosporine a, methods of preparation, and methods for use thereof

Publications (1)

Publication Number Publication Date
UA113627C2 true UA113627C2 (xx) 2017-02-27

Family

ID=46178866

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201314231A UA113627C2 (xx) 2011-05-27 2012-05-25 Кристалічна форма циклоспорину a, фармацевтична композиція та спосіб лікування

Country Status (19)

Country Link
US (4) US8772245B2 (uk)
EP (2) EP3521302A1 (uk)
JP (1) JP6163482B2 (uk)
KR (1) KR102079402B1 (uk)
CN (1) CN103649108B (uk)
AR (1) AR086586A1 (uk)
AU (4) AU2012262513B2 (uk)
BR (1) BR112013030554B1 (uk)
CA (1) CA2836946C (uk)
CL (1) CL2013003400A1 (uk)
IL (2) IL229475A0 (uk)
MX (1) MX362271B (uk)
MY (1) MY180581A (uk)
RU (1) RU2602062C2 (uk)
SG (1) SG10201607344UA (uk)
TW (1) TWI554522B (uk)
UA (1) UA113627C2 (uk)
WO (1) WO2012166610A1 (uk)
ZA (1) ZA201308665B (uk)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2779993B1 (en) 2011-11-15 2018-04-04 Allergan, Inc. Autoclavable suspensions of cyclosporin a form 2
CN108175742B (zh) * 2011-11-15 2021-10-22 阿勒根公司 环孢菌素形式2的持续作用型制剂
AU2012339693B2 (en) * 2011-11-15 2017-09-07 Allergan, Inc. Cyclosporine A Form 2 and method of making same
AU2012339632A1 (en) * 2011-11-15 2014-06-05 Allergan, Inc. Suspensions of cyclosporin A Form 2
JP2015519368A (ja) 2012-06-01 2015-07-09 アラーガン インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ シクロスポリンａ類似体
GB201222455D0 (en) * 2012-12-13 2013-01-30 Perioc Ltd Novel pharmaceutical formulations and their use in the treatment of periodontaldisease
US10524661B2 (en) * 2013-06-12 2020-01-07 Proactive Live, Inc. Sleep monitoring and stimulation
MY196111A (en) 2014-07-18 2023-03-15 Allergan Inc Suspension Compositions of Cyclosporin a for Subconjunctival and Periocular Injection
US9914755B2 (en) 2015-01-08 2018-03-13 Allergan, Inc. Cyclosporin derivatives wherein the MeBmt sidechain has been cyclized
US10443292B2 (en) * 2016-04-25 2019-10-15 Magna Closures, Inc. Non-contact obstacle detection system for motor vehicles
BR112019024040A2 (pt) * 2017-05-17 2020-09-24 Yuyu Pharma, Inc. peptídeo e composição farmacêutica para tratamen-to de doenças oculares comprendendo o mesmo peptídeo como ingrediente ativo
US11613558B2 (en) 2018-11-14 2023-03-28 Yuyu Pharma, Inc. Peptides and pharmaceutical compositions for treating eye diseases
WO2024085235A1 (ja) * 2022-10-20 2024-04-25 中外製薬株式会社 環状ペプチドの結晶の製造方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU203564B (en) * 1987-12-21 1991-08-28 Sandoz Ag Process for producing new orthorombos cyclosporin without solvatation
GB9105705D0 (en) * 1991-03-18 1991-05-01 Sandoz Ltd Improvements in or relating to organic compounds
US5474979A (en) 1994-05-17 1995-12-12 Allergan, Inc. Nonirritating emulsions for sensitive tissue
US6254860B1 (en) * 1999-04-13 2001-07-03 Allergan Sales, Inc. Ocular treatment using cyclosporin-A derivatives
US6656504B1 (en) * 1999-09-09 2003-12-02 Elan Pharma International Ltd. Nanoparticulate compositions comprising amorphous cyclosporine and methods of making and using such compositions
BRPI0811538A2 (pt) * 2007-05-04 2015-08-11 Allergan Inc Uso de ciclosporinas no tratamento de pacientes com lentes intraoculares.
BRPI0822221A2 (pt) * 2008-01-04 2015-06-23 Alcon Pharmaceuticals Ltd Composições aquosas e estáveis de ciclosporina

Also Published As

Publication number Publication date
JP2014515372A (ja) 2014-06-30
US8772245B2 (en) 2014-07-08
CN103649108B (zh) 2017-03-29
CL2013003400A1 (es) 2014-08-18
US20210269484A1 (en) 2021-09-02
AU2012262513A1 (en) 2013-12-12
EP2714720A1 (en) 2014-04-09
US20130023482A1 (en) 2013-01-24
AR086586A1 (es) 2014-01-08
AU2012262513B2 (en) 2016-03-17
NZ618213A (en) 2016-05-27
AU2017265008A1 (en) 2017-12-07
US9206228B2 (en) 2015-12-08
CN103649108A (zh) 2014-03-19
TWI554522B (zh) 2016-10-21
JP6163482B2 (ja) 2017-07-12
AU2019204192B2 (en) 2021-02-04
MX362271B (es) 2019-01-10
KR20140047054A (ko) 2014-04-21
KR102079402B1 (ko) 2020-02-19
IL290158A (en) 2022-03-01
CA2836946A1 (en) 2012-12-06
MY180581A (en) 2020-12-02
RU2602062C2 (ru) 2016-11-10
EP2714720B1 (en) 2018-12-26
AU2019204192A1 (en) 2019-07-04
ZA201308665B (en) 2014-07-30
AU2016203990A1 (en) 2016-06-30
US20160083432A1 (en) 2016-03-24
EP3521302A1 (en) 2019-08-07
MX2013013855A (es) 2014-02-17
TW201311730A (zh) 2013-03-16
BR112013030554A2 (pt) 2016-09-06
IL229475A0 (en) 2014-01-30
NZ719272A (en) 2017-10-27
US20140315827A1 (en) 2014-10-23
BR112013030554B1 (pt) 2020-12-15
SG10201607344UA (en) 2016-10-28
RU2013155033A (ru) 2015-07-20
CA2836946C (en) 2017-08-01
WO2012166610A1 (en) 2012-12-06

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