EA201490516A1 - Бифенилкарбоксиамиды в качестве ингибиторов rock-киназ - Google Patents

Бифенилкарбоксиамиды в качестве ингибиторов rock-киназ

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Publication number
EA201490516A1
EA201490516A1 EA201490516A EA201490516A EA201490516A1 EA 201490516 A1 EA201490516 A1 EA 201490516A1 EA 201490516 A EA201490516 A EA 201490516A EA 201490516 A EA201490516 A EA 201490516A EA 201490516 A1 EA201490516 A1 EA 201490516A1
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Eurasian Patent Office
Prior art keywords
inhibitors
diseases
rock
relates
present
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EA201490516A
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English (en)
Inventor
Йо Ален
Сандро Боланд
Арно Пьер Жан Бурен
Оливье Дефер
Дирк Лейзен
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Амакем Нв
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Publication of EA201490516A1 publication Critical patent/EA201490516A1/ru

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Abstract

Настоящее изобретение относится к новым ингибиторам киназ, а именно к ингибиторам ROCK, к композициям, в частности фармацевтическим препаратам, содержащим такие ингибиторы, и к применениям таких ингибиторов в лечении и профилактике заболеваний. В частности, настоящее изобретение относится к новым ингибиторам ROCK, к композициям, в частности фармацевтическим препаратам, содержащим такие ингибиторы, и к применениям таких ингибиторов в лечении и профилактике заболеваний. Помимо этого, настоящее изобретение относится к способам лечения и использованию указанных соединений в производстве лекарственного препарата для применения при ряде терапевтических показаний, включая сексуальную дисфункцию, воспалительные заболевания, глазные заболевания, желудочно-кишечные заболевания и респираторные заболевания.
EA201490516A 2011-08-31 2012-08-31 Бифенилкарбоксиамиды в качестве ингибиторов rock-киназ EA201490516A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11179491 2011-08-31
PCT/EP2012/067018 WO2013030367A1 (en) 2011-08-31 2012-08-31 Biphenylcarboxamides as rock kinase inhibitors

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EA201490516A1 true EA201490516A1 (ru) 2014-07-30

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EA201490495A EA024232B1 (ru) 2011-08-31 2012-08-31 Новые легкоразрушающиеся ингибиторы rock
EA201490515A EA201490515A1 (ru) 2011-08-31 2012-08-31 Новые ингибиторы rock-киназ
EA201490516A EA201490516A1 (ru) 2011-08-31 2012-08-31 Бифенилкарбоксиамиды в качестве ингибиторов rock-киназ

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EA201490515A EA201490515A1 (ru) 2011-08-31 2012-08-31 Новые ингибиторы rock-киназ

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US (3) US9067889B2 (ru)
EP (3) EP2751078A1 (ru)
JP (3) JP2014525426A (ru)
KR (2) KR20140072879A (ru)
CN (3) CN103874682A (ru)
AU (3) AU2012300834A1 (ru)
BR (3) BR112014004447A2 (ru)
CA (3) CA2846694A1 (ru)
EA (3) EA024232B1 (ru)
ES (1) ES2560830T3 (ru)
IL (2) IL231122A0 (ru)
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PT (1) PT2751080E (ru)
SG (2) SG11201400058PA (ru)
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