JP2014514927A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2014514927A5 JP2014514927A5 JP2014504319A JP2014504319A JP2014514927A5 JP 2014514927 A5 JP2014514927 A5 JP 2014514927A5 JP 2014504319 A JP2014504319 A JP 2014504319A JP 2014504319 A JP2014504319 A JP 2014504319A JP 2014514927 A5 JP2014514927 A5 JP 2014514927A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- antigen
- specific
- administered
- dendritic cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000001744 T-lymphocyte Anatomy 0.000 claims 19
- 238000000034 method Methods 0.000 claims 15
- 239000000427 antigen Substances 0.000 claims 11
- 102000036639 antigens Human genes 0.000 claims 11
- 108091007433 antigens Proteins 0.000 claims 11
- 210000004443 dendritic cell Anatomy 0.000 claims 9
- 206010028980 Neoplasm Diseases 0.000 claims 6
- 230000000735 allogeneic effect Effects 0.000 claims 5
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 5
- 210000004698 lymphocyte Anatomy 0.000 claims 5
- 210000004027 cell Anatomy 0.000 claims 4
- 239000003446 ligand Substances 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 210000003819 peripheral blood mononuclear cell Anatomy 0.000 claims 4
- 101000831496 Homo sapiens Toll-like receptor 3 Proteins 0.000 claims 3
- 102100024324 Toll-like receptor 3 Human genes 0.000 claims 3
- 238000012258 culturing Methods 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 230000037452 priming Effects 0.000 claims 3
- 102000006306 Antigen Receptors Human genes 0.000 claims 2
- 108010083359 Antigen Receptors Proteins 0.000 claims 2
- 108010019670 Chimeric Antigen Receptors Proteins 0.000 claims 2
- 101000669447 Homo sapiens Toll-like receptor 4 Proteins 0.000 claims 2
- 102000008070 Interferon-gamma Human genes 0.000 claims 2
- 108010074328 Interferon-gamma Proteins 0.000 claims 2
- 108090000172 Interleukin-15 Proteins 0.000 claims 2
- 108010002350 Interleukin-2 Proteins 0.000 claims 2
- 108010002586 Interleukin-7 Proteins 0.000 claims 2
- 108091036414 Polyinosinic:polycytidylic acid Proteins 0.000 claims 2
- 108091008874 T cell receptors Proteins 0.000 claims 2
- 102000016266 T-Cell Antigen Receptors Human genes 0.000 claims 2
- 229940124614 TLR 8 agonist Drugs 0.000 claims 2
- 102100039360 Toll-like receptor 4 Human genes 0.000 claims 2
- 108060008682 Tumor Necrosis Factor Proteins 0.000 claims 2
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 claims 2
- 238000004113 cell culture Methods 0.000 claims 2
- 229960003130 interferon gamma Drugs 0.000 claims 2
- 229940022511 therapeutic cancer vaccine Drugs 0.000 claims 2
- 102000004121 Annexin A5 Human genes 0.000 claims 1
- 108090000672 Annexin A5 Proteins 0.000 claims 1
- 102100027207 CD27 antigen Human genes 0.000 claims 1
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 claims 1
- 102100039620 Granulocyte-macrophage colony-stimulating factor Human genes 0.000 claims 1
- 101000914511 Homo sapiens CD27 antigen Proteins 0.000 claims 1
- 101000914514 Homo sapiens T-cell-specific surface glycoprotein CD28 Proteins 0.000 claims 1
- 101000669402 Homo sapiens Toll-like receptor 7 Proteins 0.000 claims 1
- -1 IL-1β Proteins 0.000 claims 1
- 102000006992 Interferon-alpha Human genes 0.000 claims 1
- 108010047761 Interferon-alpha Proteins 0.000 claims 1
- 102000003996 Interferon-beta Human genes 0.000 claims 1
- 108090000467 Interferon-beta Proteins 0.000 claims 1
- 108090000978 Interleukin-4 Proteins 0.000 claims 1
- 102000043129 MHC class I family Human genes 0.000 claims 1
- 108091054437 MHC class I family Proteins 0.000 claims 1
- 102000043131 MHC class II family Human genes 0.000 claims 1
- 108091054438 MHC class II family Proteins 0.000 claims 1
- 206010070834 Sensitisation Diseases 0.000 claims 1
- 102100027213 T-cell-specific surface glycoprotein CD28 Human genes 0.000 claims 1
- 102100039390 Toll-like receptor 7 Human genes 0.000 claims 1
- 230000004913 activation Effects 0.000 claims 1
- 230000005975 antitumor immune response Effects 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 210000000265 leukocyte Anatomy 0.000 claims 1
- 210000001616 monocyte Anatomy 0.000 claims 1
- 230000002062 proliferating effect Effects 0.000 claims 1
- 230000008313 sensitization Effects 0.000 claims 1
- 238000010186 staining Methods 0.000 claims 1
- 229940044616 toll-like receptor 7 agonist Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161474904P | 2011-04-13 | 2011-04-13 | |
| US61/474,904 | 2011-04-13 | ||
| PCT/EP2012/056661 WO2012140130A1 (en) | 2011-04-13 | 2012-04-12 | Method for proliferation of antigen-specific t cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017049576A Division JP6207783B2 (ja) | 2011-04-13 | 2017-03-15 | 抗原特異的ｔ細胞の増殖のための方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014514927A JP2014514927A (ja) | 2014-06-26 |
| JP2014514927A5 true JP2014514927A5 (enExample) | 2015-05-07 |
Family
ID=45937382
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014504319A Pending JP2014514927A (ja) | 2011-04-13 | 2012-04-12 | 抗原特異的ｔ細胞の増殖のための方法 |
| JP2017049576A Expired - Fee Related JP6207783B2 (ja) | 2011-04-13 | 2017-03-15 | 抗原特異的ｔ細胞の増殖のための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017049576A Expired - Fee Related JP6207783B2 (ja) | 2011-04-13 | 2017-03-15 | 抗原特異的ｔ細胞の増殖のための方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US9476028B2 (enExample) |
| EP (1) | EP2697367B1 (enExample) |
| JP (2) | JP2014514927A (enExample) |
| KR (1) | KR102028340B1 (enExample) |
| CN (1) | CN103502439B (enExample) |
| WO (1) | WO2012140130A1 (enExample) |
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5825966B2 (ja) * | 2011-10-11 | 2015-12-02 | 株式会社日本バイオセラピー研究所 | Ｃｄ５６陽性ｔ細胞増強方法 |
| RU2668816C2 (ru) * | 2012-12-18 | 2018-10-02 | Иммуникум Аб | Совместная дифференцировка моноцитов от аллогенных доноров |
| EP2934532B1 (en) | 2012-12-20 | 2019-10-23 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| EP2997134B1 (en) * | 2013-05-14 | 2020-06-24 | Board of Regents, The University of Texas System | Human application of engineered chimeric antigen receptor (car) t-cells |
| EP3572510B1 (en) | 2013-11-21 | 2022-09-21 | Repertoire Genesis Incorporation | T cell receptor and b cell receptor repertoire analysis system, and use of same in treatment and diagnosis |
| SG10201808811QA (en) * | 2014-04-10 | 2018-11-29 | Seattle Childrens Hospital Dba Seattle Childrens Res Inst | Method and compositions for cellular immunotherapy |
| ES2980788T3 (es) | 2014-04-10 | 2024-10-03 | H Lee Moffitt Cancer Ct & Res | Expansión mejorada de linfocitos infiltrantes de tumores para terapia celular adoptiva |
| WO2015164759A2 (en) | 2014-04-25 | 2015-10-29 | Bluebird Bio, Inc. | Mnd promoter chimeric antigen receptors |
| CN106456670B (zh) * | 2014-04-25 | 2020-01-07 | 蓝鸟生物公司 | 制备过继性细胞疗法的改善方法 |
| RS61406B1 (sr) | 2014-06-06 | 2021-03-31 | Bluebird Bio Inc | Poboljšane kompozicije t ćelija |
| EP3172231B1 (en) | 2014-07-24 | 2021-05-05 | Bluebird Bio, Inc. | Bcma chimeric antigen receptors |
| RU2716716C2 (ru) * | 2014-10-27 | 2020-03-16 | Фред Хатчинсон Кэнсер Рисёрч Сентер | Композиции и способы для бустинга эффективности адоптивной клеточной иммунотерапии |
| CN104593325A (zh) * | 2014-12-09 | 2015-05-06 | 深圳源正细胞医疗技术有限公司 | 诱导dc成熟并分泌高浓度促炎因子的方法 |
| US10383929B2 (en) | 2014-12-12 | 2019-08-20 | Bluebird Bio, Inc. | BCMA chimeric antigen receptors |
| US10544392B2 (en) | 2015-05-01 | 2020-01-28 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of isolating T cells and T cell receptors having antigenic specificity for a cancer-specific mutation from peripheral blood |
| PT3291821T (pt) | 2015-05-07 | 2026-03-18 | Baylor College Medicine | Imunoterapêutica com células dendríticas |
| CN114107197A (zh) * | 2015-05-13 | 2022-03-01 | 泰尔茂比司特公司 | 细胞扩增 |
| CA3172801A1 (en) * | 2015-06-12 | 2016-12-15 | Lentigen Technology, Inc. | Method to treat cancer with engineered t-cells |
| WO2017024006A1 (en) * | 2015-08-03 | 2017-02-09 | The Johns Hopkins University | Personalized, allogeneic cell therapy of cancer |
| MX2018001568A (es) | 2015-08-07 | 2019-04-25 | Seattle Children´S Hospital Dba Seattle Children´S Res Institute | Celulas t biespecificas de receptor quimerico de antigeno (car) para focalizacion a tumores solidos. |
| EP3364949A4 (en) | 2015-10-22 | 2019-07-31 | ModernaTX, Inc. | CANCER VACCINES |
| WO2017099712A1 (en) | 2015-12-07 | 2017-06-15 | Bluebird Bio, Inc. | Improved t cell compositions |
| JP7019578B2 (ja) * | 2015-12-30 | 2022-02-15 | セルジーン コーポレイション | Ｔリンパ球の産生方法及びそれにより産生されるｔリンパ球 |
| WO2017120481A1 (en) * | 2016-01-08 | 2017-07-13 | Prospect CharterCare RWMC, LLC d/b/a Roger Williams Medical Center | Geriatric car-t cells and uses thereof |
| CN108697777A (zh) * | 2016-02-08 | 2018-10-23 | 国立大学法人三重大学 | 对免疫检查点抑制剂抵抗性肿瘤的t细胞输注疗法的预处理药物 |
| CA3019835A1 (en) | 2016-04-08 | 2017-10-12 | Purdue Research Foundation | Methods and compositions for car t cell therapy |
| LT3444334T (lt) | 2016-04-15 | 2021-12-10 | Kyoto University | Antigenui specifinių cd8 teigiamų t ląstelių indikavimo būdas |
| WO2017192924A1 (en) | 2016-05-04 | 2017-11-09 | Fred Hutchinson Cancer Research Center | Cell-based neoantigen vaccines and uses thereof |
| CN109715196A (zh) | 2016-06-13 | 2019-05-03 | 转矩医疗股份有限公司 | 用于促进免疫细胞功能的组合物和方法 |
| JP7054397B2 (ja) * | 2016-06-27 | 2022-04-13 | ジュノー セラピューティクス インコーポレイテッド | Ｍｈｃ－ｅ拘束性エピトープ、結合分子ならびに関連する方法および使用 |
| CN107779433A (zh) * | 2016-08-30 | 2018-03-09 | 天津市康婷生物工程有限公司 | 便捷的刺激nk细胞增殖和分化的饲养层制备方法 |
| JP2018042481A (ja) * | 2016-09-13 | 2018-03-22 | テラ株式会社 | 抗原特異的ｔ細胞含有組成物及びその製造方法 |
| CN110099998A (zh) | 2016-10-26 | 2019-08-06 | 艾欧凡斯生物治疗公司 | 冷冻保存的肿瘤浸润淋巴细胞的再刺激 |
| TWI788307B (zh) | 2016-10-31 | 2023-01-01 | 美商艾歐凡斯生物治療公司 | 用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞 |
| MX2019005277A (es) | 2016-11-04 | 2019-09-27 | Bluebird Bio Inc | Composiciones de celulas t con car anti-bcma. |
| TWI826360B (zh) | 2016-11-17 | 2023-12-21 | 美商艾歐凡斯生物治療公司 | 殘餘腫瘤浸潤性淋巴細胞及製備和使用彼之方法 |
| US20200078400A1 (en) | 2016-12-03 | 2020-03-12 | Juno Therapeutics, Inc. | Methods for determining car-t cells dosing |
| WO2018106732A1 (en) | 2016-12-05 | 2018-06-14 | Juno Therapeutics, Inc. | Production of engineered cells for adoptive cell therapy |
| WO2018111763A1 (en) | 2016-12-12 | 2018-06-21 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Chimeric transcription factor variants with augmented sensitivity to drug ligand induction of transgene expression in mammalian cells |
| ES3055314T3 (en) | 2017-01-06 | 2026-02-11 | Iovance Biotherapeutics Inc | Expansion of tumor infiltrating lymphocytes with potassium channel agonists and therapeutic uses thereof |
| AU2018219226B2 (en) | 2017-02-07 | 2024-12-19 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents |
| CN110582288B (zh) | 2017-02-28 | 2024-09-20 | 恩多塞特公司 | 用于car t细胞疗法的组合物和方法 |
| US11254913B1 (en) | 2017-03-29 | 2022-02-22 | Iovance Biotherapeutics, Inc. | Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy |
| JOP20190224A1 (ar) | 2017-03-29 | 2019-09-26 | Iovance Biotherapeutics Inc | عمليات من أجل إنتاج الخلايا اللمفاوية المرتشحة للأورام واستخداماتها في العلاج المناعي |
| JP2020517259A (ja) | 2017-04-19 | 2020-06-18 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | 操作された抗原受容体を発現する免疫細胞 |
| CN107502589A (zh) * | 2017-08-04 | 2017-12-22 | 北京世纪劲得生物技术有限公司 | 一种肿瘤浸润淋巴细胞与单个核细胞共培养方法 |
| CA3074826A1 (en) | 2017-09-05 | 2019-03-14 | Torque Therapeutics, Inc. | Therapeutic protein compositions and methods of making and using the same |
| MA51210A (fr) | 2017-12-01 | 2020-10-07 | Juno Therapeutics Inc | Procédés de dosage et de modulation de cellules génétiquement modifiées |
| EP3737743A1 (en) | 2018-01-08 | 2020-11-18 | Iovance Biotherapeutics, Inc. | Processes for generating til products enriched for tumor antigen-specific t-cells |
| WO2019144095A1 (en) | 2018-01-22 | 2019-07-25 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Methods of use for car t cells |
| AU2019218729B2 (en) | 2018-02-06 | 2025-12-04 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Fluorescein-specific CARs exhibiting optimal T cell function against FL-PLE labelled tumors |
| WO2019165121A1 (en) | 2018-02-21 | 2019-08-29 | Board Of Regents, The University Of Texas System | Methods for activation and expansion of natural killer cells and uses therof |
| JP7568224B2 (ja) | 2018-02-23 | 2024-10-16 | エンドサイト・インコーポレイテッド | Ｃａｒ ｔ細胞療法のための配列決定法 |
| WO2019183924A1 (en) * | 2018-03-30 | 2019-10-03 | Syz Cell Therapy Co. | Improved multiple antigen specific cell therapy methods |
| WO2019217753A1 (en) | 2018-05-10 | 2019-11-14 | Iovance Biotherapeutics, Inc. | Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy |
| CN108841792A (zh) * | 2018-06-14 | 2018-11-20 | 浙江大学 | 靶向cd19和ebna1基因修饰的t细胞及其制备方法与应用 |
| BR112021008549A2 (pt) | 2018-11-05 | 2022-01-04 | Iovance Biotherapeutics Inc | Método de tratamento de carcinoma pulmonar de células não pequenas com uma população de linfócitos infiltrantes de tumor |
| US12453697B2 (en) | 2018-11-05 | 2025-10-28 | Iovance Biotherapeutics, Inc. | Processes for production of tumor infiltrating lymphocytes and uses of the same in immunotherapy |
| CN109370987A (zh) * | 2018-11-23 | 2019-02-22 | 见多视光(北京)科技有限公司 | 外周血ctl细胞改良的培养方法 |
| JP2022535006A (ja) * | 2019-05-31 | 2022-08-04 | モデルナティエックス インコーポレイテッド | 増殖ｔ細胞アッセイ |
| EP3994245A1 (en) * | 2019-07-05 | 2022-05-11 | Case Western Reserve University | Priming media and methods for stem cell culture and therapy |
| IL295063A (en) | 2020-02-04 | 2022-09-01 | Seattle Childrens Hospital Dba Seattle Childrens Res Inst | Chimeric antigen receptors (car) against dinitrophenol |
| US12091681B2 (en) * | 2020-03-27 | 2024-09-17 | Mendus B.V. | Ex vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy |
| WO2022003568A1 (en) | 2020-06-30 | 2022-01-06 | Dcprime B.V. | Use of leukemia-derived cells in ovarian cancer vaccines |
| CA3195019A1 (en) | 2020-10-06 | 2022-04-14 | Maria Fardis | Treatment of nsclc patients with tumor infiltrating lymphocyte therapies |
| JP2023554395A (ja) | 2020-12-17 | 2023-12-27 | アイオバンス バイオセラピューティクス，インコーポレイテッド | Ｃｔｌａ－４及びｐｄ－１阻害剤と併用した腫瘍浸潤リンパ球療法による治療 |
| CN113234674B (zh) * | 2021-03-15 | 2023-02-07 | 青岛华赛伯曼医学细胞生物有限公司 | 一种t细胞活化扩增的方法及其应用 |
| EP4314253A2 (en) | 2021-03-25 | 2024-02-07 | Iovance Biotherapeutics, Inc. | Methods and compositions for t-cell coculture potency assays and use with cell therapy products |
| EP4507704A1 (en) | 2022-04-15 | 2025-02-19 | Iovance Biotherapeutics, Inc. | Til expansion processes using specific cytokine combinations and/or akti treatment |
| CN115068598A (zh) * | 2022-04-25 | 2022-09-20 | 福建医科大学孟超肝胆医院(福州市传染病医院) | Tlr激动剂以及包含新生抗原的免疫原性组合物在制备药物中的应用 |
| WO2025212473A1 (en) * | 2024-04-01 | 2025-10-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods to identify and selectively expand tumor antigen-specific t cells |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6821778B1 (en) * | 1993-12-01 | 2004-11-23 | The Board Of Trustees Of Leland Stanford Junior University | Methods for using dendritic cells to activate gamma/delta-T cell receptor-positive T cells |
| US5827642A (en) | 1994-08-31 | 1998-10-27 | Fred Hutchinson Cancer Research Center | Rapid expansion method ("REM") for in vitro propagation of T lymphocytes |
| ATE428769T1 (de) * | 1997-10-27 | 2009-05-15 | Univ Rockefeller | Methode und zusammensetzung zur herstellung von reifen dendritischen zellen |
| EP1814580B1 (en) * | 2004-11-24 | 2016-08-10 | Fred Hutchinson Cancer Research Center | Methods of using il-21 for adoptive immunotherapy and identification of tumor antigens |
| US9211321B2 (en) * | 2009-10-27 | 2015-12-15 | Immunicum Ab | Method for proliferation of antigen-specific T cells |
-
2012
- 2012-04-12 CN CN201280018193.2A patent/CN103502439B/zh not_active Expired - Fee Related
- 2012-04-12 US US14/110,901 patent/US9476028B2/en active Active
- 2012-04-12 EP EP12713167.0A patent/EP2697367B1/en active Active
- 2012-04-12 JP JP2014504319A patent/JP2014514927A/ja active Pending
- 2012-04-12 WO PCT/EP2012/056661 patent/WO2012140130A1/en not_active Ceased
- 2012-04-12 KR KR1020137029248A patent/KR102028340B1/ko not_active Expired - Fee Related
-
2016
- 2016-10-24 US US15/331,924 patent/US9789174B2/en active Active
-
2017
- 2017-03-15 JP JP2017049576A patent/JP6207783B2/ja not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2796379A1 (en) | Method for proliferation of antigen-specific t cells | |
| EP2696894B1 (en) | Method for priming of t cells | |
| JP2014511704A5 (enExample) | ||
| KR102028340B1 (ko) | 항원-특이적 t 세포의 증식 방법 | |
| JP6022667B2 (ja) | 炎症性ヒトＴｈ１７細胞の増殖および機能を決定的に調節するＩＣＯＳ | |
| Hont et al. | The generation and application of antigen-specific T cell therapies for cancer and viral-associated disease | |
| EP1930414B1 (en) | Method for activation treatment of antigen-presenting cell | |
| Liu et al. | Induction on differentiation and modulation of bone marrow progenitor of dendritic cell by methionine enkephalin (MENK) | |
| JP6697076B2 (ja) | ウイルス抗原特異的ｔ細胞の濃縮および拡大方法 | |
| KR102121492B1 (ko) | 면역치료를 사용하는 il-12의 유도 | |
| Li et al. | Artificial antigen-presenting cells: the booster for the obtaining of functional adoptive cells | |
| JP2010265327A (ja) | 癌抗原非特異的な標的化ｔ細胞の製造方法及び医薬 | |
| CN113444688B (zh) | 用于抗病毒抗肿瘤的人树突状细胞诱导方法及组合物 | |
| RU2520091C2 (ru) | Способ стимуляции цитотоксического иммунного ответа против клеток опухолевой линии аденокарциномы молочной железы, экспрессирующих специфические антигены, с помощью дендритных клеток, трансфецированных полиэпитопной днк-конструкцией | |
| RU2012116602A (ru) | Способ пролиферации антигенспецифических т-клеток | |
| Foster et al. | Ex-vivo uses and applications of cytokines for adoptive immunotherapy in cancer | |
| US10030227B2 (en) | Canine autologous immunotherapy using dendritic cell induced cancer killing immunocytes | |
| De Bruijn et al. | ANTIGEN BY MURINE DENDRITIC CELLS FOR PRESENTATION TO CYTOTOXIC T LYMPHOCYTES | |
| Hatoya et al. | WS/PP-071-04 Effect of interferon-gamma on immune and clinical responses in dendritic cell-based immunotherapy against cancer K. Sugiura1, K. Mito1, K. Ueda1, T. Hori1, T. Akazawa2, J. Yamate1 | |
| de Pagter et al. | Fast B-And NK-, Reconstitution Early After Unrelated Cord Blood Transplantation Compared To (UN) Related Bone Marrow Transplantation In Children | |
| Leen et al. | Multivirus-Specific T Cell Immunotherapy To Prevent Or Treat Infections Of Allogeneic Stem Cell Transplant Recipients | |
| HK1168869B (en) | Method for proliferation of antigen-specific t cells |