JP2014511709A5 - - Google Patents
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- JP2014511709A5 JP2014511709A5 JP2014506516A JP2014506516A JP2014511709A5 JP 2014511709 A5 JP2014511709 A5 JP 2014511709A5 JP 2014506516 A JP2014506516 A JP 2014506516A JP 2014506516 A JP2014506516 A JP 2014506516A JP 2014511709 A5 JP2014511709 A5 JP 2014511709A5
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- JP
- Japan
- Prior art keywords
- mir
- group
- mirna
- primer
- specific
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 229920001239 microRNA Polymers 0.000 claims 173
- 108020004388 MicroRNAs Proteins 0.000 claims 172
- 239000002679 microRNA Substances 0.000 claims 172
- 239000000523 sample Substances 0.000 claims 70
- 210000004789 organ systems Anatomy 0.000 claims 29
- 210000000056 organs Anatomy 0.000 claims 26
- 230000003902 lesions Effects 0.000 claims 24
- 229920000348 MiR-155 Polymers 0.000 claims 23
- 210000001124 Body Fluids Anatomy 0.000 claims 20
- 239000010839 body fluid Substances 0.000 claims 20
- 230000002496 gastric Effects 0.000 claims 19
- 150000001875 compounds Chemical class 0.000 claims 17
- 229920001772 MiR-203 Polymers 0.000 claims 12
- 210000001519 tissues Anatomy 0.000 claims 12
- 229920001922 Mir-145 Polymers 0.000 claims 11
- 210000004027 cells Anatomy 0.000 claims 11
- 229920000905 Mir-192/215 microRNA precursor Polymers 0.000 claims 10
- 229920002726 Mir-31 Polymers 0.000 claims 8
- 201000011510 cancer Diseases 0.000 claims 7
- 206010061218 Inflammation Diseases 0.000 claims 6
- 229920001869 Mir-126 Polymers 0.000 claims 6
- 230000000875 corresponding Effects 0.000 claims 6
- 230000004054 inflammatory process Effects 0.000 claims 6
- 229920005625 miR-34b Polymers 0.000 claims 6
- 210000002345 respiratory system Anatomy 0.000 claims 6
- 229920002862 Mir-223 Polymers 0.000 claims 4
- 238000001514 detection method Methods 0.000 claims 2
- 230000000241 respiratory Effects 0.000 claims 2
- 210000003169 Central Nervous System Anatomy 0.000 claims 1
- 206010021143 Hypoxia Diseases 0.000 claims 1
- 210000004072 Lung Anatomy 0.000 claims 1
- 229920001877 MiR-132 Polymers 0.000 claims 1
- 229920001874 Mir-127 Polymers 0.000 claims 1
- 229920002864 Mir-218 microRNA precursor family Polymers 0.000 claims 1
- 229920002828 Mir-22 Polymers 0.000 claims 1
- 229920001650 Mir-96 microRNA Polymers 0.000 claims 1
- 230000003111 delayed Effects 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 230000001146 hypoxic Effects 0.000 claims 1
- 108091007162 let-7b Proteins 0.000 claims 1
- 108091007166 let-7g Proteins 0.000 claims 1
- -1 miR-192 / miR-30e-3p Polymers 0.000 claims 1
- 229920000152 miR-382 Polymers 0.000 claims 1
- 108091007159 miR‐142 Proteins 0.000 claims 1
- 210000000653 nervous system Anatomy 0.000 claims 1
- 230000002588 toxic Effects 0.000 claims 1
- 231100000331 toxic Toxicity 0.000 claims 1
- 230000001988 toxicity Effects 0.000 claims 1
- 231100000419 toxicity Toxicity 0.000 claims 1
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161476591P | 2011-04-18 | 2011-04-18 | |
US61/476,591 | 2011-04-18 | ||
US201161478766P | 2011-04-25 | 2011-04-25 | |
US61/478,766 | 2011-04-25 | ||
US201161546431P | 2011-10-12 | 2011-10-12 | |
US61/546,431 | 2011-10-12 | ||
PCT/US2012/034098 WO2012145409A1 (en) | 2011-04-18 | 2012-04-18 | miRNA-BASED UNIVERSAL SCREENING TEST (UST) |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2017174778A Division JP2018027089A (ja) | 2011-04-18 | 2017-09-12 | miRNAに基づくユニバーサルスクリーニングテスト(UST) |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2014511709A JP2014511709A (ja) | 2014-05-19 |
JP2014511709A5 true JP2014511709A5 (ru) | 2015-06-18 |
JP6211511B2 JP6211511B2 (ja) | 2017-10-11 |
Family
ID=47041896
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014506516A Active JP6211511B2 (ja) | 2011-04-18 | 2012-04-18 | miRNAに基づくユニバーサルスクリーニングテスト(UST) |
JP2014506501A Active JP6021893B2 (ja) | 2011-04-18 | 2012-04-18 | 軽度認知機能障害(MCI)およびアルツハイマー病(AD)の早期検出ならびにモニタリングのために体液からのmiRNAを使用する方法 |
JP2017174778A Pending JP2018027089A (ja) | 2011-04-18 | 2017-09-12 | miRNAに基づくユニバーサルスクリーニングテスト(UST) |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014506501A Active JP6021893B2 (ja) | 2011-04-18 | 2012-04-18 | 軽度認知機能障害(MCI)およびアルツハイマー病(AD)の早期検出ならびにモニタリングのために体液からのmiRNAを使用する方法 |
JP2017174778A Pending JP2018027089A (ja) | 2011-04-18 | 2017-09-12 | miRNAに基づくユニバーサルスクリーニングテスト(UST) |
Country Status (9)
Country | Link |
---|---|
US (4) | US9556487B2 (ru) |
EP (4) | EP2699697B1 (ru) |
JP (3) | JP6211511B2 (ru) |
CN (3) | CN103620057B (ru) |
AU (2) | AU2012245580B2 (ru) |
CA (2) | CA2833375A1 (ru) |
ES (1) | ES2630602T3 (ru) |
RU (1) | RU2626540C2 (ru) |
WO (2) | WO2012145363A1 (ru) |
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