JP2014510748A5 - - Google Patents
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- Publication number
- JP2014510748A5 JP2014510748A5 JP2014501811A JP2014501811A JP2014510748A5 JP 2014510748 A5 JP2014510748 A5 JP 2014510748A5 JP 2014501811 A JP2014501811 A JP 2014501811A JP 2014501811 A JP2014501811 A JP 2014501811A JP 2014510748 A5 JP2014510748 A5 JP 2014510748A5
- Authority
- JP
- Japan
- Prior art keywords
- skin
- trp
- pglu
- asn
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010037844 rash Diseases 0.000 claims description 10
- 208000017520 skin disease Diseases 0.000 claims description 10
- 208000010201 Exanthema Diseases 0.000 claims description 9
- 201000005884 exanthem Diseases 0.000 claims description 9
- 230000003902 lesion Effects 0.000 claims description 9
- 208000003251 Pruritus Diseases 0.000 claims description 7
- 230000007803 itching Effects 0.000 claims description 6
- 201000004681 Psoriasis Diseases 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 5
- 208000024891 symptom Diseases 0.000 claims description 5
- 230000009385 viral infection Effects 0.000 claims description 5
- 208000029433 Herpesviridae infectious disease Diseases 0.000 claims description 4
- 206010020751 Hypersensitivity Diseases 0.000 claims description 4
- 208000006877 Insect Bites and Stings Diseases 0.000 claims description 4
- 208000002193 Pain Diseases 0.000 claims description 4
- 239000003814 drug Substances 0.000 claims description 4
- 229940079593 drug Drugs 0.000 claims description 4
- 230000000694 effects Effects 0.000 claims description 4
- 230000008961 swelling Effects 0.000 claims description 4
- 206010030113 Oedema Diseases 0.000 claims description 3
- 206010040882 skin lesion Diseases 0.000 claims description 3
- 231100000444 skin lesion Toxicity 0.000 claims description 3
- 206010006784 Burning sensation Diseases 0.000 claims 1
- 206010015150 Erythema Diseases 0.000 claims 1
- 206010063562 Radiation skin injury Diseases 0.000 claims 1
- 241000242583 Scyphozoa Species 0.000 claims 1
- 206010042674 Swelling Diseases 0.000 claims 1
- 238000005299 abrasion Methods 0.000 claims 1
- 208000035824 paresthesia Diseases 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 14
- 125000003275 alpha amino acid group Chemical group 0.000 description 5
- 150000008575 L-amino acids Chemical class 0.000 description 4
- 208000007514 Herpes zoster Diseases 0.000 description 3
- 206010053510 Venomous sting Diseases 0.000 description 3
- 239000004480 active ingredient Substances 0.000 description 3
- 102000004196 processed proteins & peptides Human genes 0.000 description 3
- 241000124008 Mammalia Species 0.000 description 2
- 125000000217 alkyl group Chemical group 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 230000035614 depigmentation Effects 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000000546 pharmaceutical excipient Substances 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- 238000004904 shortening Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 239000012049 topical pharmaceutical composition Substances 0.000 description 2
- 241000251468 Actinopterygii Species 0.000 description 1
- 208000004898 Herpes Labialis Diseases 0.000 description 1
- 208000009889 Herpes Simplex Diseases 0.000 description 1
- 101000653360 Homo sapiens Methylcytosine dioxygenase TET1 Proteins 0.000 description 1
- 241000725303 Human immunodeficiency virus Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 102100030819 Methylcytosine dioxygenase TET1 Human genes 0.000 description 1
- 206010067152 Oral herpes Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 125000005907 alkyl ester group Chemical group 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- 230000003292 diminished effect Effects 0.000 description 1
- 231100000673 dose–response relationship Toxicity 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 231100000046 skin rash Toxicity 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161468212P | 2011-03-28 | 2011-03-28 | |
| US61/468,212 | 2011-03-28 | ||
| PCT/IL2012/050105 WO2012131676A1 (en) | 2011-03-28 | 2012-03-25 | Method for treating disorders of the skin |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014510748A JP2014510748A (ja) | 2014-05-01 |
| JP2014510748A5 true JP2014510748A5 (https=) | 2015-12-17 |
| JP5872673B2 JP5872673B2 (ja) | 2016-03-01 |
Family
ID=46052836
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014501811A Active JP5872673B2 (ja) | 2011-03-28 | 2012-03-25 | 皮膚疾患を治療するための方法 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9012397B2 (https=) |
| EP (1) | EP2691103B1 (https=) |
| JP (1) | JP5872673B2 (https=) |
| KR (1) | KR101782671B1 (https=) |
| CN (1) | CN103458912B (https=) |
| AU (1) | AU2012235632B2 (https=) |
| BR (1) | BR112013023537B1 (https=) |
| CA (1) | CA2830135C (https=) |
| DK (1) | DK2691103T3 (https=) |
| ES (1) | ES2598829T3 (https=) |
| HR (1) | HRP20161006T1 (https=) |
| HU (1) | HUE030152T2 (https=) |
| IL (1) | IL228292A (https=) |
| MX (1) | MX2013011219A (https=) |
| PL (1) | PL2691103T3 (https=) |
| PT (1) | PT2691103T (https=) |
| RU (1) | RU2583137C2 (https=) |
| WO (1) | WO2012131676A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016116948A1 (en) | 2015-01-22 | 2016-07-28 | Ram Isanaka | Peptide for treating inflammatory diseases |
| BR102017010169A2 (pt) * | 2017-05-15 | 2019-02-26 | Remer Consultores Assessoria Empresarial Ltda. | composto, intermediário de síntese, uso na preparação de anticonvulsivante, composição farmacêutica anticonvulsivante |
| SG11202009257TA (en) * | 2018-03-29 | 2020-10-29 | S I S Shulov Innovative Science Ltd | Pharmaceutical compositions for inhibiting inflammatory cytokines |
| EP4034147A4 (en) * | 2019-09-26 | 2023-10-18 | S.I.S. Shulov Innovative Science Ltd. | COMPOSITIONS AND METHODS FOR TREATING DEGENERATIVE, AGE-RELATED AND TRAUMA-INDUCED DISORDERS |
| AU2020356605A1 (en) | 2019-09-26 | 2022-04-14 | S.I.S. Shulov Innovative Science Ltd. | Anti-aging compositions and methods of use thereof |
| KR102911055B1 (ko) * | 2023-05-16 | 2026-01-09 | 황현호 | 구리원사를 적용한 원단을 사용한 섬유제품 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1172391B (it) | 1983-12-23 | 1987-06-18 | Polifarma Spa | Composti tirpeptidici contenenti acido piroglutaminico e triptofano,procedimentio di produzione ed applicazioni terapeutiche |
| IT1237474B (it) * | 1989-10-05 | 1993-06-07 | Polifarma Spa | Composti tripeptidici e loro uso farmaceutico come immuno-modulatori |
| WO1992019254A1 (en) | 1991-04-24 | 1992-11-12 | Warner-Lambert Company | α-SUBSTITUTED POLYPEPTIDES HAVING THERAPEUTIC ACTIVITY |
| IL123001A (en) | 1998-01-20 | 1998-12-06 | Shulov Inst For Venom Research | Analgesic fraction from snake March and pharmacy preparations containing it |
| WO2001001748A2 (en) * | 1999-07-02 | 2001-01-11 | Genentech, Inc. | Peptide compounds that bind her2 |
| AU767940B2 (en) * | 1999-07-14 | 2003-11-27 | S.I.S Shulov Institute For Science Ltd. | Analgesic from snake venom |
| IL137820A (en) * | 2000-08-10 | 2009-06-15 | S I S Shulov Inst For Science | Pharmaceutical composition for topical administration comprising an analgesic peptide |
| AU2002307369A1 (en) * | 2001-04-13 | 2002-10-28 | Genome Therapeutics Corporation | Novel human gene relating to respiratory diseases, obesity, and inflammatory bowel disease |
| CN101048170B (zh) * | 2004-05-06 | 2011-04-13 | 生物合成实验室有限公司 | 源自响尾蛇crotalus durissus terrificus蛇毒的止痛肽的类似化合物、它们的用途、组合物、 制备和纯化方法 |
| CN101058572A (zh) * | 2007-03-13 | 2007-10-24 | 中国药科大学 | 一种新的具有抗肿瘤活性的肽类化合物 |
| CN101239178A (zh) * | 2008-03-13 | 2008-08-13 | 中国药科大学 | 一种肽类化合物的抗血栓用途 |
| US8518399B2 (en) * | 2010-11-17 | 2013-08-27 | Tamir Biotechnology, Inc. | Methods of treating infections originating from viruses in the herpesviridae family |
-
2012
- 2012-03-25 BR BR112013023537-3A patent/BR112013023537B1/pt active IP Right Grant
- 2012-03-25 HR HRP20161006TT patent/HRP20161006T1/hr unknown
- 2012-03-25 WO PCT/IL2012/050105 patent/WO2012131676A1/en not_active Ceased
- 2012-03-25 JP JP2014501811A patent/JP5872673B2/ja active Active
- 2012-03-25 EP EP12720285.1A patent/EP2691103B1/en active Active
- 2012-03-25 HU HUE12720285A patent/HUE030152T2/en unknown
- 2012-03-25 US US13/982,708 patent/US9012397B2/en active Active
- 2012-03-25 AU AU2012235632A patent/AU2012235632B2/en active Active
- 2012-03-25 CN CN201280015711.5A patent/CN103458912B/zh active Active
- 2012-03-25 MX MX2013011219A patent/MX2013011219A/es active IP Right Grant
- 2012-03-25 KR KR1020137025194A patent/KR101782671B1/ko active Active
- 2012-03-25 DK DK12720285.1T patent/DK2691103T3/en active
- 2012-03-25 PL PL12720285.1T patent/PL2691103T3/pl unknown
- 2012-03-25 ES ES12720285.1T patent/ES2598829T3/es active Active
- 2012-03-25 PT PT127202851T patent/PT2691103T/pt unknown
- 2012-03-25 CA CA2830135A patent/CA2830135C/en active Active
- 2012-03-25 RU RU2013143041/15A patent/RU2583137C2/ru active
-
2013
- 2013-09-08 IL IL228292A patent/IL228292A/en active IP Right Grant
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