ES2598829T3 - Procedimiento de tratamiento de trastornos cutáneos - Google Patents
Procedimiento de tratamiento de trastornos cutáneos Download PDFInfo
- Publication number
- ES2598829T3 ES2598829T3 ES12720285.1T ES12720285T ES2598829T3 ES 2598829 T3 ES2598829 T3 ES 2598829T3 ES 12720285 T ES12720285 T ES 12720285T ES 2598829 T3 ES2598829 T3 ES 2598829T3
- Authority
- ES
- Spain
- Prior art keywords
- amino acid
- skin
- trp
- peptide
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 208000017520 skin disease Diseases 0.000 title abstract description 4
- 238000000034 method Methods 0.000 title description 2
- 208000010201 Exanthema Diseases 0.000 abstract description 8
- 201000005884 exanthem Diseases 0.000 abstract description 8
- 206010037844 rash Diseases 0.000 abstract description 8
- 108090000765 processed proteins & peptides Proteins 0.000 abstract description 6
- 238000011282 treatment Methods 0.000 abstract description 6
- 150000008575 L-amino acids Chemical class 0.000 abstract description 4
- 208000036142 Viral infection Diseases 0.000 abstract description 4
- 231100000046 skin rash Toxicity 0.000 abstract description 4
- 230000009385 viral infection Effects 0.000 abstract description 4
- 201000004681 Psoriasis Diseases 0.000 abstract description 3
- 150000001413 amino acids Chemical group 0.000 abstract description 3
- 208000006877 Insect Bites and Stings Diseases 0.000 abstract description 2
- 206010053510 Venomous sting Diseases 0.000 abstract description 2
- 125000000217 alkyl group Chemical group 0.000 abstract description 2
- 230000000172 allergic effect Effects 0.000 abstract description 2
- 208000010668 atopic eczema Diseases 0.000 abstract description 2
- 231100000430 skin reaction Toxicity 0.000 abstract description 2
- 239000012049 topical pharmaceutical composition Substances 0.000 abstract description 2
- 239000000203 mixture Substances 0.000 abstract 2
- 206010019973 Herpes virus infection Diseases 0.000 abstract 1
- 206010063562 Radiation skin injury Diseases 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
- 208000003251 Pruritus Diseases 0.000 description 13
- 230000007803 itching Effects 0.000 description 11
- 239000006071 cream Substances 0.000 description 8
- 210000000707 wrist Anatomy 0.000 description 4
- 208000007514 Herpes zoster Diseases 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 208000025865 Ulcer Diseases 0.000 description 3
- 208000015181 infectious disease Diseases 0.000 description 3
- 230000035807 sensation Effects 0.000 description 3
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 101000653360 Homo sapiens Methylcytosine dioxygenase TET1 Proteins 0.000 description 2
- 206010020751 Hypersensitivity Diseases 0.000 description 2
- 102100030819 Methylcytosine dioxygenase TET1 Human genes 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- 208000030961 allergic reaction Diseases 0.000 description 2
- 230000003902 lesion Effects 0.000 description 2
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 231100000397 ulcer Toxicity 0.000 description 2
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 1
- FHYNZKLNCPUNEU-UHFFFAOYSA-N 4-[(3,4-dihydroxyphenyl)methyl]-3-[(4-hydroxyphenyl)methyl]oxolan-2-one Chemical compound C1=CC(O)=CC=C1CC1C(=O)OCC1CC1=CC=C(O)C(O)=C1 FHYNZKLNCPUNEU-UHFFFAOYSA-N 0.000 description 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 208000003367 Hypopigmentation Diseases 0.000 description 1
- XQFRJNBWHJMXHO-RRKCRQDMSA-N IDUR Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(I)=C1 XQFRJNBWHJMXHO-RRKCRQDMSA-N 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010072170 Skin wound Diseases 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 229940075507 glyceryl monostearate Drugs 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- WJRBRSLFGCUECM-UHFFFAOYSA-N hydantoin Chemical compound O=C1CNC(=O)N1 WJRBRSLFGCUECM-UHFFFAOYSA-N 0.000 description 1
- 230000003425 hypopigmentation Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 description 1
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 description 1
- 229960002216 methylparaben Drugs 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 235000010446 mineral oil Nutrition 0.000 description 1
- 239000001788 mono and diglycerides of fatty acids Substances 0.000 description 1
- 229960005323 phenoxyethanol Drugs 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 231100000444 skin lesion Toxicity 0.000 description 1
- 206010040882 skin lesion Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000036269 ulceration Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Birds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Meat, Egg Or Seafood Products (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161468212P | 2011-03-28 | 2011-03-28 | |
| US201161468212P | 2011-03-28 | ||
| PCT/IL2012/050105 WO2012131676A1 (en) | 2011-03-28 | 2012-03-25 | Method for treating disorders of the skin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2598829T3 true ES2598829T3 (es) | 2017-01-30 |
Family
ID=46052836
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES12720285.1T Active ES2598829T3 (es) | 2011-03-28 | 2012-03-25 | Procedimiento de tratamiento de trastornos cutáneos |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9012397B2 (https=) |
| EP (1) | EP2691103B1 (https=) |
| JP (1) | JP5872673B2 (https=) |
| KR (1) | KR101782671B1 (https=) |
| CN (1) | CN103458912B (https=) |
| AU (1) | AU2012235632B2 (https=) |
| BR (1) | BR112013023537B1 (https=) |
| CA (1) | CA2830135C (https=) |
| DK (1) | DK2691103T3 (https=) |
| ES (1) | ES2598829T3 (https=) |
| HR (1) | HRP20161006T1 (https=) |
| HU (1) | HUE030152T2 (https=) |
| IL (1) | IL228292A (https=) |
| MX (1) | MX2013011219A (https=) |
| PL (1) | PL2691103T3 (https=) |
| PT (1) | PT2691103T (https=) |
| RU (1) | RU2583137C2 (https=) |
| WO (1) | WO2012131676A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016116948A1 (en) | 2015-01-22 | 2016-07-28 | Ram Isanaka | Peptide for treating inflammatory diseases |
| BR102017010169A2 (pt) * | 2017-05-15 | 2019-02-26 | Remer Consultores Assessoria Empresarial Ltda. | composto, intermediário de síntese, uso na preparação de anticonvulsivante, composição farmacêutica anticonvulsivante |
| SG11202009257TA (en) * | 2018-03-29 | 2020-10-29 | S I S Shulov Innovative Science Ltd | Pharmaceutical compositions for inhibiting inflammatory cytokines |
| EP4034147A4 (en) * | 2019-09-26 | 2023-10-18 | S.I.S. Shulov Innovative Science Ltd. | COMPOSITIONS AND METHODS FOR TREATING DEGENERATIVE, AGE-RELATED AND TRAUMA-INDUCED DISORDERS |
| AU2020356605A1 (en) | 2019-09-26 | 2022-04-14 | S.I.S. Shulov Innovative Science Ltd. | Anti-aging compositions and methods of use thereof |
| KR102911055B1 (ko) * | 2023-05-16 | 2026-01-09 | 황현호 | 구리원사를 적용한 원단을 사용한 섬유제품 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1172391B (it) | 1983-12-23 | 1987-06-18 | Polifarma Spa | Composti tirpeptidici contenenti acido piroglutaminico e triptofano,procedimentio di produzione ed applicazioni terapeutiche |
| IT1237474B (it) * | 1989-10-05 | 1993-06-07 | Polifarma Spa | Composti tripeptidici e loro uso farmaceutico come immuno-modulatori |
| WO1992019254A1 (en) | 1991-04-24 | 1992-11-12 | Warner-Lambert Company | α-SUBSTITUTED POLYPEPTIDES HAVING THERAPEUTIC ACTIVITY |
| IL123001A (en) | 1998-01-20 | 1998-12-06 | Shulov Inst For Venom Research | Analgesic fraction from snake March and pharmacy preparations containing it |
| WO2001001748A2 (en) * | 1999-07-02 | 2001-01-11 | Genentech, Inc. | Peptide compounds that bind her2 |
| AU767940B2 (en) * | 1999-07-14 | 2003-11-27 | S.I.S Shulov Institute For Science Ltd. | Analgesic from snake venom |
| IL137820A (en) * | 2000-08-10 | 2009-06-15 | S I S Shulov Inst For Science | Pharmaceutical composition for topical administration comprising an analgesic peptide |
| AU2002307369A1 (en) * | 2001-04-13 | 2002-10-28 | Genome Therapeutics Corporation | Novel human gene relating to respiratory diseases, obesity, and inflammatory bowel disease |
| CN101048170B (zh) * | 2004-05-06 | 2011-04-13 | 生物合成实验室有限公司 | 源自响尾蛇crotalus durissus terrificus蛇毒的止痛肽的类似化合物、它们的用途、组合物、 制备和纯化方法 |
| CN101058572A (zh) * | 2007-03-13 | 2007-10-24 | 中国药科大学 | 一种新的具有抗肿瘤活性的肽类化合物 |
| CN101239178A (zh) * | 2008-03-13 | 2008-08-13 | 中国药科大学 | 一种肽类化合物的抗血栓用途 |
| US8518399B2 (en) * | 2010-11-17 | 2013-08-27 | Tamir Biotechnology, Inc. | Methods of treating infections originating from viruses in the herpesviridae family |
-
2012
- 2012-03-25 BR BR112013023537-3A patent/BR112013023537B1/pt active IP Right Grant
- 2012-03-25 HR HRP20161006TT patent/HRP20161006T1/hr unknown
- 2012-03-25 WO PCT/IL2012/050105 patent/WO2012131676A1/en not_active Ceased
- 2012-03-25 JP JP2014501811A patent/JP5872673B2/ja active Active
- 2012-03-25 EP EP12720285.1A patent/EP2691103B1/en active Active
- 2012-03-25 HU HUE12720285A patent/HUE030152T2/en unknown
- 2012-03-25 US US13/982,708 patent/US9012397B2/en active Active
- 2012-03-25 AU AU2012235632A patent/AU2012235632B2/en active Active
- 2012-03-25 CN CN201280015711.5A patent/CN103458912B/zh active Active
- 2012-03-25 MX MX2013011219A patent/MX2013011219A/es active IP Right Grant
- 2012-03-25 KR KR1020137025194A patent/KR101782671B1/ko active Active
- 2012-03-25 DK DK12720285.1T patent/DK2691103T3/en active
- 2012-03-25 PL PL12720285.1T patent/PL2691103T3/pl unknown
- 2012-03-25 ES ES12720285.1T patent/ES2598829T3/es active Active
- 2012-03-25 PT PT127202851T patent/PT2691103T/pt unknown
- 2012-03-25 CA CA2830135A patent/CA2830135C/en active Active
- 2012-03-25 RU RU2013143041/15A patent/RU2583137C2/ru active
-
2013
- 2013-09-08 IL IL228292A patent/IL228292A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| EP2691103A1 (en) | 2014-02-05 |
| CN103458912A (zh) | 2013-12-18 |
| US9012397B2 (en) | 2015-04-21 |
| WO2012131676A4 (en) | 2012-11-22 |
| PT2691103T (pt) | 2016-10-25 |
| JP5872673B2 (ja) | 2016-03-01 |
| CA2830135C (en) | 2019-12-17 |
| EP2691103B1 (en) | 2016-07-20 |
| RU2583137C2 (ru) | 2016-05-10 |
| CN103458912B (zh) | 2016-01-20 |
| US20130310309A1 (en) | 2013-11-21 |
| HK1186986A1 (zh) | 2014-03-28 |
| AU2012235632A1 (en) | 2013-09-26 |
| KR20140027122A (ko) | 2014-03-06 |
| JP2014510748A (ja) | 2014-05-01 |
| HRP20161006T1 (hr) | 2016-10-21 |
| PL2691103T3 (pl) | 2016-12-30 |
| AU2012235632B2 (en) | 2015-12-03 |
| BR112013023537B1 (pt) | 2022-05-31 |
| WO2012131676A1 (en) | 2012-10-04 |
| IL228292A (en) | 2017-05-29 |
| HUE030152T2 (en) | 2017-04-28 |
| CA2830135A1 (en) | 2012-10-04 |
| MX2013011219A (es) | 2013-10-17 |
| KR101782671B1 (ko) | 2017-09-27 |
| DK2691103T3 (en) | 2016-11-21 |
| BR112013023537A2 (pt) | 2016-12-06 |
| RU2013143041A (ru) | 2015-03-27 |
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