JP2014509515A5 - - Google Patents
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- Publication number
- JP2014509515A5 JP2014509515A5 JP2013558214A JP2013558214A JP2014509515A5 JP 2014509515 A5 JP2014509515 A5 JP 2014509515A5 JP 2013558214 A JP2013558214 A JP 2013558214A JP 2013558214 A JP2013558214 A JP 2013558214A JP 2014509515 A5 JP2014509515 A5 JP 2014509515A5
- Authority
- JP
- Japan
- Prior art keywords
- biomarker
- expression level
- subject
- breast cancer
- eribulin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161454426P | 2011-03-18 | 2011-03-18 | |
| US61/454,426 | 2011-03-18 | ||
| PCT/US2012/029479 WO2012129100A1 (en) | 2011-03-18 | 2012-03-16 | Methods and compositions for predicting response to eribulin |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017046070A Division JP6612280B2 (ja) | 2011-03-18 | 2017-03-10 | エリブリンに対する応答を予測するための方法及び組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014509515A JP2014509515A (ja) | 2014-04-21 |
| JP2014509515A5 true JP2014509515A5 (https=) | 2015-04-23 |
Family
ID=45879070
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013558214A Pending JP2014509515A (ja) | 2011-03-18 | 2012-03-16 | エリブリンに対する応答を予測するための方法及び組成物 |
| JP2017046070A Expired - Fee Related JP6612280B2 (ja) | 2011-03-18 | 2017-03-10 | エリブリンに対する応答を予測するための方法及び組成物 |
| JP2019069638A Pending JP2019150027A (ja) | 2011-03-18 | 2019-04-01 | エリブリンに対する応答を予測するための方法及び組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017046070A Expired - Fee Related JP6612280B2 (ja) | 2011-03-18 | 2017-03-10 | エリブリンに対する応答を予測するための方法及び組成物 |
| JP2019069638A Pending JP2019150027A (ja) | 2011-03-18 | 2019-04-01 | エリブリンに対する応答を予測するための方法及び組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9637795B2 (https=) |
| EP (1) | EP2686441B1 (https=) |
| JP (3) | JP2014509515A (https=) |
| CN (1) | CN103562406B (https=) |
| CA (1) | CA2828959A1 (https=) |
| ES (1) | ES2731653T3 (https=) |
| SG (2) | SG193489A1 (https=) |
| WO (1) | WO2012129100A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102369008B (zh) | 2009-03-30 | 2014-10-29 | 卫材R&D管理有限公司 | 脂质体组合物 |
| RU2689977C2 (ru) * | 2012-12-04 | 2019-05-30 | Эйсай Ар Энд Ди Менеджмент Ко., Лтд. | Применение эрибулина для лечения рака молочной железы |
| BR112015029386B1 (pt) * | 2013-06-26 | 2023-11-14 | Eisai R&D Management Co., Ltd. | Uso de eribulina e lenvatinibe como terapia de combinação e kit |
| US20170100367A1 (en) * | 2014-05-28 | 2017-04-13 | Eisai R&D Management Co., Ltd. | Use of eribulin in the treatment of cancer |
| WO2015184145A1 (en) * | 2014-05-28 | 2015-12-03 | Eisai R&D Management Co., Ltd. | Use of eribulin and poly (adp ribose) polymerase (parp) inhibitors as combination therapy for the treatment of cancer |
| AU2016226157B2 (en) * | 2015-03-04 | 2022-01-27 | Eisai R&D Management Co., Ltd. | Combination of a PD-1 antagonist and eribulin for treating cancer |
| US10669545B2 (en) | 2015-05-01 | 2020-06-02 | Japan Science And Technology Agency | Tumor cell malignant transformation suppressor and anti-tumor agent |
| PE20231050A1 (es) | 2016-03-02 | 2023-07-11 | Eisai Randd Man Co Ltd | Conjugados de anticuerpo y farmaco basados en eribulina y metodos para su uso |
| WO2017188350A1 (ja) | 2016-04-28 | 2017-11-02 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 腫瘍の成長を抑制する方法 |
| WO2019097073A1 (en) | 2017-11-20 | 2019-05-23 | Basilea Pharmaceutica International AG | Pharmaceutical combinations for use in the treatment of neoplastic diseases |
| WO2020179712A1 (en) * | 2019-03-01 | 2020-09-10 | Eisai R&D Management Co., Ltd. | Methods for predicting tumor response to eribulin |
| US12036204B2 (en) | 2019-07-26 | 2024-07-16 | Eisai R&D Management Co., Ltd. | Pharmaceutical composition for treating tumor |
| US11083705B2 (en) | 2019-07-26 | 2021-08-10 | Eisai R&D Management Co., Ltd. | Pharmaceutical composition for treating tumor |
| CN113174427B (zh) * | 2021-04-29 | 2023-02-28 | 遵义医科大学 | 基于DNA分子检测ERGIC3 mRNA的方法 |
| CN113512733B (zh) * | 2021-05-13 | 2022-07-26 | 浙江工业大学 | 一种电化学nhk反应合成艾日布林中间体的方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5075216A (en) | 1988-09-23 | 1991-12-24 | Cetus Corporation | Methods for dna sequencing with thermus aquaticus dna polymerase |
| US5800992A (en) | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
| US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
| US6040138A (en) | 1995-09-15 | 2000-03-21 | Affymetrix, Inc. | Expression monitoring by hybridization to high density oligonucleotide arrays |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| CA2124087C (en) | 1991-11-22 | 2002-10-01 | James L. Winkler | Combinatorial strategies for polymer synthesis |
| DE69433811T2 (de) | 1993-01-07 | 2005-06-23 | Sequenom, Inc., San Diego | Dns - sequenzierung durch massenspektronomie |
| US5556752A (en) | 1994-10-24 | 1996-09-17 | Affymetrix, Inc. | Surface-bound, unimolecular, double-stranded DNA |
| US5545531A (en) | 1995-06-07 | 1996-08-13 | Affymax Technologies N.V. | Methods for making a device for concurrently processing multiple biological chip assays |
| US5854033A (en) | 1995-11-21 | 1998-12-29 | Yale University | Rolling circle replication reporter systems |
| EP0880598A4 (en) | 1996-01-23 | 2005-02-23 | Affymetrix Inc | RAPID EVALUATION OF NUCLEIC ACID ABUNDANCE DIFFERENCE, WITH A HIGH-DENSITY OLIGONUCLEOTIDE SYSTEM |
| DE69829402T2 (de) | 1997-10-31 | 2006-04-13 | Affymetrix, Inc. (a Delaware Corp.), Santa Clara | Expressionsprofile in adulten und fötalen organen |
| US6020135A (en) | 1998-03-27 | 2000-02-01 | Affymetrix, Inc. | P53-regulated genes |
| US6653341B1 (en) | 1998-06-17 | 2003-11-25 | Eisai Co., Ltd. | Methods and compositions for use in treating cancer |
| JP4454151B2 (ja) | 1998-06-17 | 2010-04-21 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 大環状類似体及びそれらの使用並びに調製方法 |
| US8097648B2 (en) | 1998-06-17 | 2012-01-17 | Eisai R&D Management Co., Ltd. | Methods and compositions for use in treating cancer |
| WO2005032347A2 (en) * | 2003-10-01 | 2005-04-14 | The Ohio State University Research Foundation | Determining the chemosensitivity of cells to cytotoxic agents |
| US20060154312A1 (en) * | 2004-12-09 | 2006-07-13 | Sergei Agoulnik | Tubulin isotype screening in cancer therapy using halichondrin B analogs |
| TW201132813A (en) * | 2010-03-03 | 2011-10-01 | Koo Foundation Sun Yat Sen Cancer Ct | Methods for classifying and treating breast cancers |
-
2012
- 2012-03-16 EP EP12710643.3A patent/EP2686441B1/en active Active
- 2012-03-16 CA CA2828959A patent/CA2828959A1/en not_active Abandoned
- 2012-03-16 US US14/001,737 patent/US9637795B2/en not_active Expired - Fee Related
- 2012-03-16 ES ES12710643T patent/ES2731653T3/es active Active
- 2012-03-16 SG SG2013069646A patent/SG193489A1/en unknown
- 2012-03-16 JP JP2013558214A patent/JP2014509515A/ja active Pending
- 2012-03-16 CN CN201280013701.8A patent/CN103562406B/zh not_active Expired - Fee Related
- 2012-03-16 SG SG10201602147YA patent/SG10201602147YA/en unknown
- 2012-03-16 WO PCT/US2012/029479 patent/WO2012129100A1/en not_active Ceased
-
2017
- 2017-03-10 JP JP2017046070A patent/JP6612280B2/ja not_active Expired - Fee Related
-
2019
- 2019-04-01 JP JP2019069638A patent/JP2019150027A/ja active Pending
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