JP2012517241A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012517241A5 JP2012517241A5 JP2011550213A JP2011550213A JP2012517241A5 JP 2012517241 A5 JP2012517241 A5 JP 2012517241A5 JP 2011550213 A JP2011550213 A JP 2011550213A JP 2011550213 A JP2011550213 A JP 2011550213A JP 2012517241 A5 JP2012517241 A5 JP 2012517241A5
- Authority
- JP
- Japan
- Prior art keywords
- sample
- bcl
- gene
- patient
- tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15174909P | 2009-02-11 | 2009-02-11 | |
| US61/151,749 | 2009-02-11 | ||
| PCT/US2010/023818 WO2010093742A1 (en) | 2009-02-11 | 2010-02-11 | Methods and compositions for identifying, classifying and monitoring subject having bcl-2 family inhibitor-resistant tumors and cancers |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015162761A Division JP2016047044A (ja) | 2009-02-11 | 2015-08-20 | Ｂｃｌ−２ファミリー阻害剤耐性腫瘍及び癌を有する被験者を同定、分類及びモニターするための方法及び組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012517241A JP2012517241A (ja) | 2012-08-02 |
| JP2012517241A5 true JP2012517241A5 (https=) | 2013-03-28 |
Family
ID=42112120
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011550213A Pending JP2012517241A (ja) | 2009-02-11 | 2010-02-11 | Ｂｃｌ−２ファミリー阻害剤耐性腫瘍及び癌を有する被験者を同定、分類及びモニターするための方法及び組成物 |
| JP2015162761A Pending JP2016047044A (ja) | 2009-02-11 | 2015-08-20 | Ｂｃｌ−２ファミリー阻害剤耐性腫瘍及び癌を有する被験者を同定、分類及びモニターするための方法及び組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015162761A Pending JP2016047044A (ja) | 2009-02-11 | 2015-08-20 | Ｂｃｌ−２ファミリー阻害剤耐性腫瘍及び癌を有する被験者を同定、分類及びモニターするための方法及び組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9045800B2 (https=) |
| EP (1) | EP2396427A1 (https=) |
| JP (2) | JP2012517241A (https=) |
| CN (1) | CN102388151A (https=) |
| CA (1) | CA2751293A1 (https=) |
| MX (1) | MX2011008488A (https=) |
| WO (1) | WO2010093742A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102062416B1 (ko) * | 2012-05-10 | 2020-01-03 | 유트로픽스 파마슈티컬스, 인크. | 실용 가능한 암 진단 대체 법 |
| US20150150869A1 (en) | 2012-06-20 | 2015-06-04 | Eutropics Pharmaceuticals, Inc. | Methods and compositions useful for treating diseases involving bcl-2 family proteins with quinoline derivatives |
| EP2922544B1 (en) | 2012-11-21 | 2018-08-01 | Eutropics Pharmaceuticals, Inc. | Methods and compositions useful for treating diseases involving bcl-2 family proteins with quinoline derivatives |
| WO2015017788A1 (en) | 2013-08-01 | 2015-02-05 | Eutropics Pharmaceuticals, Inc. | Method for predicting cancer sensitivity |
| WO2015066305A1 (en) | 2013-10-30 | 2015-05-07 | Eutropics Pharmaceuticals, Inc. | Methods for determining chemosensitivity and chemotoxicity |
| US10793915B2 (en) | 2015-01-12 | 2020-10-06 | Eutropics Pharmaceuticals, Inc. | Context dependent diagnostics test for guiding cancer treatment |
| US9901574B2 (en) | 2015-04-20 | 2018-02-27 | Tolero Pharmaceuticals, Inc. | Predicting response to alvocidib by mitochondrial profiling |
| ES2739749T3 (es) | 2015-05-18 | 2020-02-03 | Tolero Pharmaceuticals Inc | Profármacos de alvocidib que tienen biodisponibilidad aumentada |
| MX2018001289A (es) | 2015-08-03 | 2018-04-30 | Tolero Pharmaceuticals Inc | Terapias de combinacion para el tratamiento del cancer. |
| KR102376764B1 (ko) | 2016-08-05 | 2022-03-18 | 더 리젠츠 오브 더 유니버시티 오브 미시건 | Bcl-2 억제제로서의 n-(페닐설포닐)벤즈아미드 및 관련 화합물 |
| WO2018094275A1 (en) | 2016-11-18 | 2018-05-24 | Tolero Pharmaceuticals, Inc. | Alvocidib prodrugs and their use as protein kinase inhibitors |
| KR20190099260A (ko) | 2016-12-19 | 2019-08-26 | 톨레로 파마수티컬스, 인크. | 프로파일링 펩티드 및 감도 프로파일링을 위한 방법 |
| WO2019055579A1 (en) | 2017-09-12 | 2019-03-21 | Tolero Pharmaceuticals, Inc. | TREATMENT REGIME FOR CANCERS THAT ARE INSENSITIVE TO BCL-2 INHIBITORS USING THE MCL-1 ALVOCIDIB INHIBITOR |
| CA3094449C (en) | 2018-07-31 | 2023-02-28 | Ascentage Pharma (Suzhou) Co., Ltd. | Combination product of bcl-2 inhibitor and mdm2 inhibitor and use thereof in the prevention and/or treatment of diseases |
| TWI725488B (zh) | 2018-07-31 | 2021-04-21 | 大陸商蘇州亞盛藥業有限公司 | Bcl-2抑制劑與化療藥的組合產品及其在預防及/或治療疾病中的用途 |
| JP2021516262A (ja) | 2018-07-31 | 2021-07-01 | アセンテージ ファーマ（スーチョウ）カンパニー，リミティド | リツキシマブ及び／若しくはベンダムスチンと組み合わされたＢｃｌ−２阻害剤又はＣＨＯＰと組み合わされたＢｃｌ−２阻害剤の相乗的な抗腫瘍効果 |
| CN110772521A (zh) | 2018-07-31 | 2020-02-11 | 苏州亚盛药业有限公司 | Bcl-2抑制剂或Bcl-2/Bcl-xL抑制剂与BTK抑制剂的组合产品及其用途 |
| US11034710B2 (en) | 2018-12-04 | 2021-06-15 | Sumitomo Dainippon Pharma Oncology, Inc. | CDK9 inhibitors and polymorphs thereof for use as agents for treatment of cancer |
| US11793802B2 (en) | 2019-03-20 | 2023-10-24 | Sumitomo Pharma Oncology, Inc. | Treatment of acute myeloid leukemia (AML) with venetoclax failure |
| EP3758005A1 (en) * | 2019-06-24 | 2020-12-30 | Koninklijke Philips N.V. | Identification of the cellular function of an active nfkb pathway |
| WO2025136456A1 (en) * | 2023-07-14 | 2025-06-26 | Eil Therapeutics, Inc. | Compounds having ((3-nitrophenyl)sulfonyl)acetamide as bcl-2 inhibitors |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL63907A0 (en) | 1980-09-24 | 1981-12-31 | Cetus Corp | Diagnostic method and antibody probe for use therein |
| ATE53862T1 (de) | 1982-01-22 | 1990-06-15 | Cetus Corp | Verfahren zur charakterisierung von hla und die darin benutzten cdns-testmittel. |
| US4582788A (en) * | 1982-01-22 | 1986-04-15 | Cetus Corporation | HLA typing method and cDNA probes used therein |
| US4948882A (en) * | 1983-02-22 | 1990-08-14 | Syngene, Inc. | Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis |
| US4683194A (en) * | 1984-05-29 | 1987-07-28 | Cetus Corporation | Method for detection of polymorphic restriction sites and nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5756696A (en) * | 1986-01-16 | 1998-05-26 | Regents Of The University Of California | Compositions for chromosome-specific staining |
| US5447841A (en) * | 1986-01-16 | 1995-09-05 | The Regents Of The Univ. Of California | Methods for chromosome-specific staining |
| CA1284931C (en) | 1986-03-13 | 1991-06-18 | Henry A. Erlich | Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids |
| CA1338457C (en) | 1986-08-22 | 1996-07-16 | Henry A. Erlich | Purified thermostable enzyme |
| US5006309A (en) | 1988-04-22 | 1991-04-09 | Abbott Laboratories | Immunoassay device with liquid transfer between wells by washing |
| US5089424A (en) * | 1988-06-14 | 1992-02-18 | Abbott Laboratories | Method and apparatus for heterogeneous chemiluminescence assay |
| US5063081A (en) | 1988-11-14 | 1991-11-05 | I-Stat Corporation | Method of manufacturing a plurality of uniform microfabricated sensing devices having an immobilized ligand receptor |
| US5231020A (en) | 1989-03-30 | 1993-07-27 | Dna Plant Technology Corporation | Genetic engineering of novel plant phenotypes |
| US5491224A (en) | 1990-09-20 | 1996-02-13 | Bittner; Michael L. | Direct label transaminated DNA probe compositions for chromosome identification and methods for their manufacture |
| US5464746A (en) * | 1991-12-17 | 1995-11-07 | Abbott Laboratories | Haptens, tracers, immunogens and antibodies for carbazole and dibenzofuran derivatives |
| US5424414A (en) | 1991-12-17 | 1995-06-13 | Abbott Laboratories | Haptens, tracers, immunogens and antibodies for 3-phenyl-1-adamantaneacetic acids |
| US6214986B1 (en) * | 1998-10-07 | 2001-04-10 | Isis Pharmaceuticals, Inc. | Antisense modulation of bcl-x expression |
| US6395472B1 (en) * | 1999-02-05 | 2002-05-28 | Abbott Laboratories | Methods of utilizing the TT virus |
| US7419821B2 (en) * | 2002-03-05 | 2008-09-02 | I-Stat Corporation | Apparatus and methods for analyte measurement and immunoassay |
| US20040018577A1 (en) | 2002-07-29 | 2004-01-29 | Emerson Campbell John Lewis | Multiple hybrid immunoassay |
| US7723099B2 (en) | 2003-09-10 | 2010-05-25 | Abbott Point Of Care Inc. | Immunoassay device with immuno-reference electrode |
| US7682833B2 (en) * | 2003-09-10 | 2010-03-23 | Abbott Point Of Care Inc. | Immunoassay device with improved sample closure |
| CN1834261A (zh) * | 2005-11-15 | 2006-09-20 | 北京博奥生物芯片有限责任公司 | 基因分型芯片及其制备方法与应用 |
| US20080233567A1 (en) * | 2006-09-05 | 2008-09-25 | Murray William E | Companion diagnostic assays for cancer therapy |
| WO2008082673A2 (en) | 2006-12-28 | 2008-07-10 | Abbott Laboratories | Companion diagnostic assays for cancer therapy |
| MX2011004589A (es) * | 2008-10-31 | 2011-05-25 | Abbott Lab | Metodos para ensamblar paneles de lineas de celulas de cancer para uso para probar la eficiencia de una o mas composiciones farmaceuticas. |
| JP6812855B2 (ja) | 2017-03-10 | 2021-01-13 | Jnc株式会社 | ジアルキルアミノシランの製造方法 |
-
2010
- 2010-02-11 MX MX2011008488A patent/MX2011008488A/es active IP Right Grant
- 2010-02-11 JP JP2011550213A patent/JP2012517241A/ja active Pending
- 2010-02-11 CA CA2751293A patent/CA2751293A1/en not_active Abandoned
- 2010-02-11 EP EP10706075A patent/EP2396427A1/en not_active Withdrawn
- 2010-02-11 WO PCT/US2010/023818 patent/WO2010093742A1/en not_active Ceased
- 2010-02-11 CN CN2010800160886A patent/CN102388151A/zh active Pending
- 2010-02-11 US US12/704,165 patent/US9045800B2/en not_active Expired - Fee Related
-
2015
- 2015-04-06 US US14/679,889 patent/US20150211075A1/en not_active Abandoned
- 2015-08-20 JP JP2015162761A patent/JP2016047044A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2012517241A5 (https=) | ||
| JP2013500001A5 (https=) | ||
| CN111662982B (zh) | 用于脑胶质瘤早期诊断和/或复发监测的生物标志物及其应用 | |
| RU2014120427A (ru) | Определение микрорнк в плазме для обнаружения ранних стадий колоректального рака | |
| CN102333887B (zh) | 用于检测gi癌转移的方法 | |
| JP2019150027A5 (https=) | ||
| JP2014509515A5 (https=) | ||
| EP2036987A1 (en) | Molecular markers for tumor cell content in tissue samples | |
| WO2016029260A1 (en) | Treatment and detection of melanoma | |
| TWI682034B (zh) | 用於評估子宮內膜癌的發展風險或診斷子宮內膜癌的方法 | |
| CN114032308A (zh) | Fam83a、kpna2、krt6a和ldha联合作为肺腺癌生物标志物的用途 | |
| CN110592223B (zh) | 一种NSCLC的诊断和预后标记物hsa_circRNA_012515的应用 | |
| TW201625797A (zh) | 評估罹患大腸直腸癌風險的方法及標誌物 | |
| TWI598444B (zh) | 用以評估乳癌罹患風險之方法及基因標記 | |
| CN111315897B (zh) | 用于黑素瘤检测的方法 | |
| KR102241455B1 (ko) | 조기 간암 진단을 위한 엑소좀 유래 microRNA 바이오마커 및 그 용도 | |
| CN112813167B (zh) | 标志物linc01977及其应用 | |
| CN110577999A (zh) | 一种cxcr4作为胃癌预后评估生物标志物的应用及诊断试剂盒 | |
| CN116287180A (zh) | 检测标志物的试剂在制备用于诊断哮喘的试剂盒中的应用 | |
| CN118922561A (zh) | 肾癌诊断用尿液miRNA标志物、诊断试剂及试剂盒 | |
| EP2716767A1 (en) | Method for determining the prognosis of pancreatic cancer | |
| JP2014003925A (ja) | 予後不良の肺小細胞がんの検査方法及び治療手段 | |
| US20150087549A1 (en) | Methods of using tissue biomarkers for indication of progression from barretts esophagus to esophageal adenocarcinoma | |
| US20120149027A1 (en) | Method for Determining the Risk of Metastasis as an Indicator for Diagnostic Imaging | |
| ES2856232A1 (es) | Biomarcadores para predecir la respuesta de un sujeto a una terapia con bcg, metodos y usos basados en los mismos |