JP2014506923A5 - - Google Patents
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- JP2014506923A5 JP2014506923A5 JP2013556608A JP2013556608A JP2014506923A5 JP 2014506923 A5 JP2014506923 A5 JP 2014506923A5 JP 2013556608 A JP2013556608 A JP 2013556608A JP 2013556608 A JP2013556608 A JP 2013556608A JP 2014506923 A5 JP2014506923 A5 JP 2014506923A5
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- 239000000203 mixture Substances 0.000 claims description 77
- 238000000034 method Methods 0.000 claims description 40
- 241001465754 Metazoa Species 0.000 claims description 15
- 230000001684 chronic effect Effects 0.000 claims description 14
- 239000000284 extract Substances 0.000 claims description 13
- 230000000694 effects Effects 0.000 claims description 12
- 230000002757 inflammatory effect Effects 0.000 claims description 12
- 244000005706 microflora Species 0.000 claims description 10
- 150000001875 compounds Chemical class 0.000 claims description 8
- 239000011159 matrix material Substances 0.000 claims description 8
- 230000007246 mechanism Effects 0.000 claims description 8
- 239000002609 medium Substances 0.000 claims description 8
- 230000018612 quorum sensing Effects 0.000 claims description 8
- 230000028327 secretion Effects 0.000 claims description 8
- 230000006378 damage Effects 0.000 claims description 7
- 239000006041 probiotic Substances 0.000 claims description 7
- 235000018291 probiotics Nutrition 0.000 claims description 7
- 230000004071 biological effect Effects 0.000 claims description 6
- 239000002537 cosmetic Substances 0.000 claims description 6
- 230000005764 inhibitory process Effects 0.000 claims description 6
- 239000004094 surface-active agent Substances 0.000 claims description 6
- 206010006451 bronchitis Diseases 0.000 claims description 5
- 230000009036 growth inhibition Effects 0.000 claims description 5
- 201000001245 periodontitis Diseases 0.000 claims description 5
- 230000002265 prevention Effects 0.000 claims description 5
- 230000000529 probiotic effect Effects 0.000 claims description 5
- 241000736262 Microbiota Species 0.000 claims description 4
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- 239000012472 biological sample Substances 0.000 claims description 4
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- 206010039083 rhinitis Diseases 0.000 claims description 4
- 206010006458 Bronchitis chronic Diseases 0.000 claims description 3
- 208000003556 Dry Eye Syndromes Diseases 0.000 claims description 3
- 206010013774 Dry eye Diseases 0.000 claims description 3
- 206010061218 Inflammation Diseases 0.000 claims description 3
- 208000005141 Otitis Diseases 0.000 claims description 3
- 208000007451 chronic bronchitis Diseases 0.000 claims description 3
- 208000001277 chronic periodontitis Diseases 0.000 claims description 3
- 208000027157 chronic rhinosinusitis Diseases 0.000 claims description 3
- 208000019258 ear infection Diseases 0.000 claims description 3
- 230000004054 inflammatory process Effects 0.000 claims description 3
- 206010033072 otitis externa Diseases 0.000 claims description 3
- 239000008194 pharmaceutical composition Substances 0.000 claims description 3
- 230000000241 respiratory effect Effects 0.000 claims description 3
- 206010001076 Acute sinusitis Diseases 0.000 claims description 2
- 208000007882 Gastritis Diseases 0.000 claims description 2
- 208000038016 acute inflammation Diseases 0.000 claims description 2
- 230000006022 acute inflammation Effects 0.000 claims description 2
- 201000009329 acute pericementitis Diseases 0.000 claims description 2
- 239000003242 anti bacterial agent Substances 0.000 claims description 2
- 229940088710 antibiotic agent Drugs 0.000 claims description 2
- 210000005252 bulbus oculi Anatomy 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims description 2
- 208000037976 chronic inflammation Diseases 0.000 claims description 2
- 230000006020 chronic inflammation Effects 0.000 claims description 2
- 201000009151 chronic rhinitis Diseases 0.000 claims description 2
- 239000003581 cosmetic carrier Substances 0.000 claims description 2
- 239000003937 drug carrier Substances 0.000 claims description 2
- 230000002526 effect on cardiovascular system Effects 0.000 claims description 2
- 238000000605 extraction Methods 0.000 claims description 2
- 239000000835 fiber Substances 0.000 claims description 2
- 208000021302 gastroesophageal reflux disease Diseases 0.000 claims description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 claims description 2
- 239000001963 growth medium Substances 0.000 claims description 2
- 239000004615 ingredient Substances 0.000 claims description 2
- 230000002934 lysing effect Effects 0.000 claims description 2
- 201000009240 nasopharyngitis Diseases 0.000 claims description 2
- 210000000056 organ Anatomy 0.000 claims description 2
- 210000003300 oropharynx Anatomy 0.000 claims description 2
- 239000003002 pH adjusting agent Substances 0.000 claims description 2
- 230000003239 periodontal effect Effects 0.000 claims description 2
- 239000000419 plant extract Substances 0.000 claims description 2
- 235000013406 prebiotics Nutrition 0.000 claims description 2
- 210000002345 respiratory system Anatomy 0.000 claims description 2
- 230000000087 stabilizing effect Effects 0.000 claims description 2
- 239000000126 substance Substances 0.000 claims description 2
- 238000011200 topical administration Methods 0.000 claims description 2
- 239000011782 vitamin Substances 0.000 claims description 2
- 229940088594 vitamin Drugs 0.000 claims description 2
- 229930003231 vitamin Natural products 0.000 claims description 2
- 235000013343 vitamin Nutrition 0.000 claims description 2
- 244000005700 microbiome Species 0.000 claims 6
- 230000000813 microbial effect Effects 0.000 claims 5
- 230000028993 immune response Effects 0.000 claims 4
- 241000191967 Staphylococcus aureus Species 0.000 claims 3
- 230000001737 promoting effect Effects 0.000 claims 3
- 241000606768 Haemophilus influenzae Species 0.000 claims 2
- 241000192132 Leuconostoc Species 0.000 claims 2
- 230000033228 biological regulation Effects 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 241000193798 Aerococcus Species 0.000 claims 1
- 241000228212 Aspergillus Species 0.000 claims 1
- 241000193830 Bacillus <bacterium> Species 0.000 claims 1
- 241000222120 Candida <Saccharomycetales> Species 0.000 claims 1
- 241000186216 Corynebacterium Species 0.000 claims 1
- 241000194033 Enterococcus Species 0.000 claims 1
- 241000588724 Escherichia coli Species 0.000 claims 1
- 241000605909 Fusobacterium Species 0.000 claims 1
- 241000194036 Lactococcus Species 0.000 claims 1
- RJQXTJLFIWVMTO-TYNCELHUSA-N Methicillin Chemical compound COC1=CC=CC(OC)=C1C(=O)N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@@H]21 RJQXTJLFIWVMTO-TYNCELHUSA-N 0.000 claims 1
- 241000192041 Micrococcus Species 0.000 claims 1
- 241000202223 Oenococcus Species 0.000 claims 1
- 241000192001 Pediococcus Species 0.000 claims 1
- 241000191992 Peptostreptococcus Species 0.000 claims 1
- 241000589516 Pseudomonas Species 0.000 claims 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 claims 1
- 241000235070 Saccharomyces Species 0.000 claims 1
- 241000204117 Sporolactobacillus Species 0.000 claims 1
- 206010041925 Staphylococcal infections Diseases 0.000 claims 1
- 241000191940 Staphylococcus Species 0.000 claims 1
- 241000191963 Staphylococcus epidermidis Species 0.000 claims 1
- 241000194017 Streptococcus Species 0.000 claims 1
- 241000202221 Weissella Species 0.000 claims 1
- 230000003214 anti-biofilm Effects 0.000 claims 1
- 230000003110 anti-inflammatory effect Effects 0.000 claims 1
- 230000000845 anti-microbial effect Effects 0.000 claims 1
- 229940047650 haemophilus influenzae Drugs 0.000 claims 1
- 244000005702 human microbiome Species 0.000 claims 1
- 231100001231 less toxic Toxicity 0.000 claims 1
- 208000015688 methicillin-resistant staphylococcus aureus infectious disease Diseases 0.000 claims 1
- 229960003085 meticillin Drugs 0.000 claims 1
- 230000006641 stabilisation Effects 0.000 claims 1
- 238000011105 stabilization Methods 0.000 claims 1
- 206010012438 Dermatitis atopic Diseases 0.000 description 2
- 201000008937 atopic dermatitis Diseases 0.000 description 2
- 210000000987 immune system Anatomy 0.000 description 2
- 230000004968 inflammatory condition Effects 0.000 description 2
- 230000028709 inflammatory response Effects 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 201000002909 Aspergillosis Diseases 0.000 description 1
- 208000036641 Aspergillus infections Diseases 0.000 description 1
- 201000003883 Cystic fibrosis Diseases 0.000 description 1
- 208000037581 Persistent Infection Diseases 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000032770 biofilm formation Effects 0.000 description 1
- 210000005069 ears Anatomy 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000007310 pathophysiology Effects 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161447735P | 2011-03-01 | 2011-03-01 | |
| US61/447,735 | 2011-03-01 | ||
| PCT/US2011/059370 WO2012118535A1 (en) | 2011-03-01 | 2011-11-04 | Materials and methods for treating conditions associated with pathogenic biofilm |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016148281A Division JP6594269B2 (ja) | 2011-03-01 | 2016-07-28 | 病原性バイオフィルムと関連した状態を治療するための物質および方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014506923A JP2014506923A (ja) | 2014-03-20 |
| JP2014506923A5 true JP2014506923A5 (https=) | 2014-05-29 |
Family
ID=45440615
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013556608A Pending JP2014506923A (ja) | 2011-03-01 | 2011-11-04 | 病原性バイオフィルムと関連した状態を治療するための物質および方法 |
| JP2016148281A Active JP6594269B2 (ja) | 2011-03-01 | 2016-07-28 | 病原性バイオフィルムと関連した状態を治療するための物質および方法 |
| JP2018195775A Active JP6908568B2 (ja) | 2011-03-01 | 2018-10-17 | 病原性バイオフィルムと関連した状態を治療するための物質および方法 |
| JP2021036803A Pending JP2021080303A (ja) | 2011-03-01 | 2021-03-09 | 病原性バイオフィルムと関連した状態を治療するための物質および方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016148281A Active JP6594269B2 (ja) | 2011-03-01 | 2016-07-28 | 病原性バイオフィルムと関連した状態を治療するための物質および方法 |
| JP2018195775A Active JP6908568B2 (ja) | 2011-03-01 | 2018-10-17 | 病原性バイオフィルムと関連した状態を治療するための物質および方法 |
| JP2021036803A Pending JP2021080303A (ja) | 2011-03-01 | 2021-03-09 | 病原性バイオフィルムと関連した状態を治療するための物質および方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (11) | US9504739B2 (https=) |
| EP (1) | EP2680866A1 (https=) |
| JP (4) | JP2014506923A (https=) |
| CN (2) | CN103687604A (https=) |
| WO (1) | WO2012118535A1 (https=) |
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| JP5548121B2 (ja) | 2007-05-14 | 2014-07-16 | リサーチ ファウンデーション オブ ステイト ユニバーシティ オブ ニューヨーク | バイオフィルム中の細菌細胞における生理学的分散応答の誘導 |
| DK3564357T3 (da) | 2010-02-01 | 2022-06-20 | Rebiotix Inc | Bakterieterapi mod clostridium difficile colitis |
| CN103687604A (zh) | 2011-03-01 | 2014-03-26 | 群体创新有限责任公司 | 用于治疗与致病生物膜相关之病症的材料和方法 |
| EP2836224A4 (en) | 2012-02-29 | 2015-12-16 | Ethicon Endo Surgery Inc | COMPOSITIONS OF BIOZOOSE AND RELATED METHODS |
| US10557234B2 (en) | 2012-05-29 | 2020-02-11 | Neozyme International, Inc. | Papermaking additive compositions and methods and uses thereof |
| US10681914B2 (en) | 2012-05-29 | 2020-06-16 | Neozyme International, Inc. | Non-toxic plant agent compositions and methods and uses thereof |
| US10334856B2 (en) | 2012-05-29 | 2019-07-02 | Neozyme International, Inc. | Non-toxic pest control compositions and methods and uses thereof |
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2011
- 2011-11-04 CN CN201180070309.2A patent/CN103687604A/zh active Pending
- 2011-11-04 WO PCT/US2011/059370 patent/WO2012118535A1/en not_active Ceased
- 2011-11-04 EP EP11802987.5A patent/EP2680866A1/en active Pending
- 2011-11-04 JP JP2013556608A patent/JP2014506923A/ja active Pending
- 2011-11-04 CN CN202010329772.5A patent/CN111518866A/zh active Pending
- 2011-11-04 US US13/503,325 patent/US9504739B2/en active Active
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