JP2014040431A5 - - Google Patents

Download PDF

Info

Publication number
JP2014040431A5
JP2014040431A5 JP2013194484A JP2013194484A JP2014040431A5 JP 2014040431 A5 JP2014040431 A5 JP 2014040431A5 JP 2013194484 A JP2013194484 A JP 2013194484A JP 2013194484 A JP2013194484 A JP 2013194484A JP 2014040431 A5 JP2014040431 A5 JP 2014040431A5
Authority
JP
Japan
Prior art keywords
seq
residues
pth
collagen
polypeptide fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013194484A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014040431A (ja
JP5821066B2 (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2014040431A publication Critical patent/JP2014040431A/ja
Publication of JP2014040431A5 publication Critical patent/JP2014040431A5/ja
Application granted granted Critical
Publication of JP5821066B2 publication Critical patent/JP5821066B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2013194484A 2007-04-09 2013-09-19 コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク Active JP5821066B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92243307P 2007-04-09 2007-04-09
US60/922,433 2007-04-09

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2010503048A Division JP5520811B2 (ja) 2007-04-09 2008-04-09 コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015173678A Division JP5989876B2 (ja) 2007-04-09 2015-09-03 コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク

Publications (3)

Publication Number Publication Date
JP2014040431A JP2014040431A (ja) 2014-03-06
JP2014040431A5 true JP2014040431A5 (enExample) 2014-10-02
JP5821066B2 JP5821066B2 (ja) 2015-11-24

Family

ID=39831527

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2010503048A Active JP5520811B2 (ja) 2007-04-09 2008-04-09 コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク
JP2013194484A Active JP5821066B2 (ja) 2007-04-09 2013-09-19 コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク
JP2015173678A Active JP5989876B2 (ja) 2007-04-09 2015-09-03 コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク
JP2016157345A Active JP6366653B2 (ja) 2007-04-09 2016-08-10 コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2010503048A Active JP5520811B2 (ja) 2007-04-09 2008-04-09 コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2015173678A Active JP5989876B2 (ja) 2007-04-09 2015-09-03 コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク
JP2016157345A Active JP6366653B2 (ja) 2007-04-09 2016-08-10 コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク

Country Status (7)

Country Link
US (6) US8450273B2 (enExample)
EP (2) EP3091075B1 (enExample)
JP (4) JP5520811B2 (enExample)
CA (2) CA2930681C (enExample)
DK (2) DK3091075T3 (enExample)
ES (2) ES2675174T3 (enExample)
WO (1) WO2008124166A2 (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2675174T3 (es) * 2007-04-09 2018-07-09 The Board Of Trustees Of The University Of Arkansas Proteínas de fusión de un dominio de enlazamiento a colágeno y hormona paratiroidea
EP2363461B1 (en) * 2008-11-19 2014-12-24 Meiji Seika Pharma Co., Ltd. Fusion collagenase to which affinity tag is attached, and method for producing same
EP2405008A1 (en) * 2010-07-06 2012-01-11 LanthioPep B.V. Bacterial surface display of thioether-bridge-containing peptides
US9173919B2 (en) 2011-02-16 2015-11-03 Purdue Research Foundation Collagen-targeted nanoparticles
US9248164B2 (en) 2011-05-13 2016-02-02 School Juridical Person Kitasato Institute Growth factor anchoring type bone graft material, method for producing growth factor anchoring type bone graft material, kit for producing growth factor anchoring type bone graft material, and method for forming bone
US9579273B2 (en) 2011-12-14 2017-02-28 The Kitasato Institute Delivery of therapeutic agents by a collagen binding protein
WO2013120060A1 (en) 2012-02-09 2013-08-15 The Board Of Trustees Of The University Of Arkansas Delivery of therapeutic agents by a collagen binding protein
US8969290B2 (en) * 2012-06-26 2015-03-03 Worcester Polytechnic Institute Matrix scaffold with antimicrobial activity
WO2016085280A1 (ko) 2014-11-28 2016-06-02 서울대학교산학협력단 세포 투과성 스테이플 펩타이드, 이의 제조방법 및 그 용도
WO2016197491A1 (en) 2015-06-12 2016-12-15 Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences A three-dimensional tissue scaffold with stem cell attracting element and use thereof
CN109069659B (zh) 2016-03-01 2022-04-19 阿森迪斯药物骨疾病股份有限公司 Pth前药
DK3518982T3 (da) 2016-09-29 2025-02-03 Ascendis Pharma Bone Diseases As Pth-forbindelser med kontrolleret frigivelse
IL304086A (en) 2016-09-29 2023-08-01 Ascendis Pharma Bone Diseases As Dosing regimen for a controlled-release PTH compound
NZ792622A (en) 2016-09-29 2025-08-29 Ascendis Pharma Bone Diseases As Pth compounds with low peak-to-trough ratios
CN110114065A (zh) * 2016-11-30 2019-08-09 珀杜研究基金会 通过甲状旁腺激素受体刺激进行的骨折靶向性骨再生
WO2018148573A1 (en) * 2017-02-10 2018-08-16 The Board Of Trustees Of The University Of Arkansas Collagen-binding agent compositions and methods of using the same
GB201706781D0 (en) 2017-04-28 2017-06-14 Univ Sheffield Parathyroid hormone fusion polypeptide
CN107213517B (zh) * 2017-05-17 2020-03-27 宁波大学 一种复合骨水泥及其制备方法
EP3685849A4 (en) * 2017-09-22 2021-12-22 Asahi Kasei Pharma Corporation LIQUID PHARMACEUTICAL COMPOSITION CONTAINING TERIPARATIDE WITH EXCELLENT STABILITY
KR101964376B1 (ko) * 2017-09-29 2019-04-01 주식회사 나이벡 부갑상선호르몬(parathyroid hormone, PTH)에 골조직 선택성 펩타이드가 결합되어 있는 융합 펩타이드를 포함하는 약학 조성물 및 생체재료
EP3796941A4 (en) 2018-05-30 2022-12-28 Purdue Research Foundation Targeting anabolic drugs for accelerated fracture repair
MY209748A (en) 2019-02-11 2025-07-31 Ascendis Pharma Bone Diseases As Liquid pharmaceutical formulations of pth conjugates
WO2021030196A1 (en) * 2019-08-09 2021-02-18 Phasebio Pharmaceuticals, Inc. Elp fusion proteins comprising parathyroid hormone for controlled and sustained release
US12403179B2 (en) 2021-02-18 2025-09-02 The Board Of Trustees Of The University Of Arkansas Release of growth factors at wound healing stages
KR20250075704A (ko) 2022-09-30 2025-05-28 익스텐드 바이오사이언시즈, 인크. 장기-지속형 부갑상선 호르몬

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8516421D0 (en) 1985-06-28 1985-07-31 Biotechnology Interface Ltd Fibronectins
WO1994022468A1 (en) 1993-04-02 1994-10-13 Anticancer, Inc. Method for delivering beneficial compositions to hair follicles
US5925552A (en) 1996-04-25 1999-07-20 Medtronic, Inc. Method for attachment of biomolecules to medical devices surfaces
EP0917537B1 (en) 1996-07-31 2005-09-07 The General Hospital Corporation Novel parathyroid hormone-related peptide analogs
US6428579B1 (en) 1998-07-01 2002-08-06 Brown University Research Foundation Implantable prosthetic devices coated with bioactive molecules
US6387663B1 (en) 1998-07-31 2002-05-14 University Of Southern California Targeting pharmaceutical agents to injured tissues
US7601685B2 (en) 1998-08-27 2009-10-13 Eidgenossische Technische Hochschule Zurich Growth factor modified protein matrices for tissue engineering
JP2001190280A (ja) * 1999-02-19 2001-07-17 Terumo Corp コラーゲン結合性生理活性ポリペプチド
US20020102709A1 (en) * 1999-02-19 2002-08-01 Tetsuya Ishikawa Collagen-binding physiologically active polypeptide
WO2000049159A1 (en) 1999-02-19 2000-08-24 Terumo Kabushiki Kaisha Collagen-binding physiologically active polypeptide
US6908994B1 (en) 1999-05-10 2005-06-21 The Texas A&M University System Collagen-binding proteins from enterococcal bacteria
US20050124537A1 (en) 2000-04-27 2005-06-09 Amgen Inc. Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
US20040053368A1 (en) 2000-08-15 2004-03-18 Tetsuya Ishikawa Collagen-binding hybrid polypeptide
JP2002058485A (ja) 2000-08-16 2002-02-26 Terumo Corp コラーゲン結合性を有する骨形成促進融合蛋白質
US20020063621A1 (en) 2000-09-01 2002-05-30 Next Planet, Inc. Method and apparatus for device communications
US6812217B2 (en) 2000-12-04 2004-11-02 Medtronic, Inc. Medical device and methods of use
ES2301697T3 (es) 2001-12-18 2008-07-01 Eidgenossisch Technische Hochschule Zurich Matrices de proteina modificada con factor de crecimiento para ingenieria de tejidos.
US7429383B2 (en) 2002-07-25 2008-09-30 The General Hospital Corporation Parathyroid hormone receptor activation and hematopoietic progenitor cell expansion
US7060299B2 (en) 2002-12-31 2006-06-13 Battelle Memorial Institute Biodegradable microparticles that stabilize and control the release of proteins
DE60307683T2 (de) 2003-02-13 2008-05-15 Synthes Gmbh Injizierbare mischung zum ersatz von knochengewebe in situ
US20040220094A1 (en) 2003-05-01 2004-11-04 Skinner Keith K. Inverse agonist and agonist peptides that stimulate/inhibit hair growth
JP4836798B2 (ja) 2003-10-21 2011-12-14 アイジーエフ オンコロジー エルエルシー 癌を治療するための化合物および方法
US20050119183A1 (en) * 2003-11-12 2005-06-02 Nps Allelix Corp. Method for treating bone loss using parathyroid hormone
EP1557176A1 (en) 2004-01-26 2005-07-27 Ferring B.V. Treatment of bone metastases by means of PTH receptor agonists
US20090005298A1 (en) 2004-02-27 2009-01-01 The University Of Western Ontario Bone Sialoprotein Collagen-Binding Peptides
HUE055861T2 (hu) 2004-04-21 2021-12-28 Alexion Pharma Inc Csontbejuttató konjugátumok és azok alkalmazási módszere fehérjék csonthoz kötéséhez
JP2008517917A (ja) 2004-10-21 2008-05-29 アイジーエフ オンコロジー エルエルシー 癌を治療するための毒素および放射性核種結合igf−1受容体リガンド
WO2006073711A2 (en) * 2005-01-06 2006-07-13 Kuros Biosurgery Ag Use of a matrix comprising a contrast agent in soft tissues
EP1970382B1 (en) 2005-12-26 2011-06-29 Yantai Zhenghai Bio-Technology Co., Ltd. Activated collagen scaffold materials and their special fused active restoration factors
ES2675174T3 (es) 2007-04-09 2018-07-09 The Board Of Trustees Of The University Of Arkansas Proteínas de fusión de un dominio de enlazamiento a colágeno y hormona paratiroidea
JP2010172247A (ja) 2009-01-29 2010-08-12 Kitasato Institute 積層型高密度培養人工組織の製造方法及び積層型高密度培養人工組織
JPWO2011142425A1 (ja) 2010-05-12 2013-07-22 国立大学法人 香川大学 上皮層含有組織の再生材および再生評価方法
US9248164B2 (en) 2011-05-13 2016-02-02 School Juridical Person Kitasato Institute Growth factor anchoring type bone graft material, method for producing growth factor anchoring type bone graft material, kit for producing growth factor anchoring type bone graft material, and method for forming bone
US9579273B2 (en) 2011-12-14 2017-02-28 The Kitasato Institute Delivery of therapeutic agents by a collagen binding protein
WO2013120060A1 (en) 2012-02-09 2013-08-15 The Board Of Trustees Of The University Of Arkansas Delivery of therapeutic agents by a collagen binding protein

Similar Documents

Publication Publication Date Title
JP2014040431A5 (enExample)
JP2016532693A5 (enExample)
MX2011009810A (es) Composiciones y metodos para usar proteinas de union multiespecificas que comprenden una combinacion anticuerporeceptor.
WO2014089169A4 (en) Immunotherapy with binding agents
JP2015525217A5 (enExample)
JP2010523671A5 (enExample)
MY192113A (en) Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment of anti-adm non-ig protein scaffold for reducing the risk of mortality in a patient having a chronic or acute disease or acute condition
EA201100072A1 (ru) Новые композиции и способы
IN2014KN01713A (enExample)
JP2015120706A5 (enExample)
MX2014000054A (es) Moleculas de union anti-alfa sinucleina.
HRP20190799T1 (hr) Imunocitokini na bazi il-15 i sushi domene il-15r alfa
NZ602943A (en) Modified binding proteins inhibiting the vegf-a receptor interaction
EP3412304A3 (en) Hla-a24 agonist epitopes of muc1-c oncoprotein and compositions and methods of use
JP2012082206A5 (enExample)
MX340014B (es) Composicion farmaceutica para el tratamiento y/o prevencion del cancer.
MX2012008998A (es) Composicion farmaceutica para el tratamiento y/o prevencion del cancer.
MX342291B (es) Composicion farmaceutica para el tratamiento y/o prevencion del cancer.
JP2010189394A5 (enExample)
NZ612161A (en) Radiolabled her2 binding peptides
MX2017006016A (es) Composiciones conjugadas de xten direccionadas y metodos para producir las mismas.
NZ603813A (en) Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-trna synthetases
PE20141727A1 (es) Composiciones, usos y metodos para tratamiento de trastornos y enfermedades metabolicas
HK1220376A1 (zh) 修饰的毒素
PE20140133A1 (es) Nuevas proteinas de union a antigenos