JP2014040431A5 - - Google Patents
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- Publication number
- JP2014040431A5 JP2014040431A5 JP2013194484A JP2013194484A JP2014040431A5 JP 2014040431 A5 JP2014040431 A5 JP 2014040431A5 JP 2013194484 A JP2013194484 A JP 2013194484A JP 2013194484 A JP2013194484 A JP 2013194484A JP 2014040431 A5 JP2014040431 A5 JP 2014040431A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- residues
- pth
- collagen
- polypeptide fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92243307P | 2007-04-09 | 2007-04-09 | |
| US60/922,433 | 2007-04-09 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010503048A Division JP5520811B2 (ja) | 2007-04-09 | 2008-04-09 | コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015173678A Division JP5989876B2 (ja) | 2007-04-09 | 2015-09-03 | コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014040431A JP2014040431A (ja) | 2014-03-06 |
| JP2014040431A5 true JP2014040431A5 (enExample) | 2014-10-02 |
| JP5821066B2 JP5821066B2 (ja) | 2015-11-24 |
Family
ID=39831527
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010503048A Active JP5520811B2 (ja) | 2007-04-09 | 2008-04-09 | コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク |
| JP2013194484A Active JP5821066B2 (ja) | 2007-04-09 | 2013-09-19 | コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク |
| JP2015173678A Active JP5989876B2 (ja) | 2007-04-09 | 2015-09-03 | コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク |
| JP2016157345A Active JP6366653B2 (ja) | 2007-04-09 | 2016-08-10 | コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010503048A Active JP5520811B2 (ja) | 2007-04-09 | 2008-04-09 | コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015173678A Active JP5989876B2 (ja) | 2007-04-09 | 2015-09-03 | コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク |
| JP2016157345A Active JP6366653B2 (ja) | 2007-04-09 | 2016-08-10 | コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク |
Country Status (7)
| Country | Link |
|---|---|
| US (6) | US8450273B2 (enExample) |
| EP (2) | EP3091075B1 (enExample) |
| JP (4) | JP5520811B2 (enExample) |
| CA (2) | CA2930681C (enExample) |
| DK (2) | DK3091075T3 (enExample) |
| ES (2) | ES2675174T3 (enExample) |
| WO (1) | WO2008124166A2 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2675174T3 (es) * | 2007-04-09 | 2018-07-09 | The Board Of Trustees Of The University Of Arkansas | Proteínas de fusión de un dominio de enlazamiento a colágeno y hormona paratiroidea |
| EP2363461B1 (en) * | 2008-11-19 | 2014-12-24 | Meiji Seika Pharma Co., Ltd. | Fusion collagenase to which affinity tag is attached, and method for producing same |
| EP2405008A1 (en) * | 2010-07-06 | 2012-01-11 | LanthioPep B.V. | Bacterial surface display of thioether-bridge-containing peptides |
| US9173919B2 (en) | 2011-02-16 | 2015-11-03 | Purdue Research Foundation | Collagen-targeted nanoparticles |
| US9248164B2 (en) | 2011-05-13 | 2016-02-02 | School Juridical Person Kitasato Institute | Growth factor anchoring type bone graft material, method for producing growth factor anchoring type bone graft material, kit for producing growth factor anchoring type bone graft material, and method for forming bone |
| US9579273B2 (en) | 2011-12-14 | 2017-02-28 | The Kitasato Institute | Delivery of therapeutic agents by a collagen binding protein |
| WO2013120060A1 (en) | 2012-02-09 | 2013-08-15 | The Board Of Trustees Of The University Of Arkansas | Delivery of therapeutic agents by a collagen binding protein |
| US8969290B2 (en) * | 2012-06-26 | 2015-03-03 | Worcester Polytechnic Institute | Matrix scaffold with antimicrobial activity |
| WO2016085280A1 (ko) | 2014-11-28 | 2016-06-02 | 서울대학교산학협력단 | 세포 투과성 스테이플 펩타이드, 이의 제조방법 및 그 용도 |
| WO2016197491A1 (en) | 2015-06-12 | 2016-12-15 | Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences | A three-dimensional tissue scaffold with stem cell attracting element and use thereof |
| CN109069659B (zh) | 2016-03-01 | 2022-04-19 | 阿森迪斯药物骨疾病股份有限公司 | Pth前药 |
| DK3518982T3 (da) | 2016-09-29 | 2025-02-03 | Ascendis Pharma Bone Diseases As | Pth-forbindelser med kontrolleret frigivelse |
| IL304086A (en) | 2016-09-29 | 2023-08-01 | Ascendis Pharma Bone Diseases As | Dosing regimen for a controlled-release PTH compound |
| NZ792622A (en) | 2016-09-29 | 2025-08-29 | Ascendis Pharma Bone Diseases As | Pth compounds with low peak-to-trough ratios |
| CN110114065A (zh) * | 2016-11-30 | 2019-08-09 | 珀杜研究基金会 | 通过甲状旁腺激素受体刺激进行的骨折靶向性骨再生 |
| WO2018148573A1 (en) * | 2017-02-10 | 2018-08-16 | The Board Of Trustees Of The University Of Arkansas | Collagen-binding agent compositions and methods of using the same |
| GB201706781D0 (en) | 2017-04-28 | 2017-06-14 | Univ Sheffield | Parathyroid hormone fusion polypeptide |
| CN107213517B (zh) * | 2017-05-17 | 2020-03-27 | 宁波大学 | 一种复合骨水泥及其制备方法 |
| EP3685849A4 (en) * | 2017-09-22 | 2021-12-22 | Asahi Kasei Pharma Corporation | LIQUID PHARMACEUTICAL COMPOSITION CONTAINING TERIPARATIDE WITH EXCELLENT STABILITY |
| KR101964376B1 (ko) * | 2017-09-29 | 2019-04-01 | 주식회사 나이벡 | 부갑상선호르몬(parathyroid hormone, PTH)에 골조직 선택성 펩타이드가 결합되어 있는 융합 펩타이드를 포함하는 약학 조성물 및 생체재료 |
| EP3796941A4 (en) | 2018-05-30 | 2022-12-28 | Purdue Research Foundation | Targeting anabolic drugs for accelerated fracture repair |
| MY209748A (en) | 2019-02-11 | 2025-07-31 | Ascendis Pharma Bone Diseases As | Liquid pharmaceutical formulations of pth conjugates |
| WO2021030196A1 (en) * | 2019-08-09 | 2021-02-18 | Phasebio Pharmaceuticals, Inc. | Elp fusion proteins comprising parathyroid hormone for controlled and sustained release |
| US12403179B2 (en) | 2021-02-18 | 2025-09-02 | The Board Of Trustees Of The University Of Arkansas | Release of growth factors at wound healing stages |
| KR20250075704A (ko) | 2022-09-30 | 2025-05-28 | 익스텐드 바이오사이언시즈, 인크. | 장기-지속형 부갑상선 호르몬 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8516421D0 (en) | 1985-06-28 | 1985-07-31 | Biotechnology Interface Ltd | Fibronectins |
| WO1994022468A1 (en) | 1993-04-02 | 1994-10-13 | Anticancer, Inc. | Method for delivering beneficial compositions to hair follicles |
| US5925552A (en) | 1996-04-25 | 1999-07-20 | Medtronic, Inc. | Method for attachment of biomolecules to medical devices surfaces |
| EP0917537B1 (en) | 1996-07-31 | 2005-09-07 | The General Hospital Corporation | Novel parathyroid hormone-related peptide analogs |
| US6428579B1 (en) | 1998-07-01 | 2002-08-06 | Brown University Research Foundation | Implantable prosthetic devices coated with bioactive molecules |
| US6387663B1 (en) | 1998-07-31 | 2002-05-14 | University Of Southern California | Targeting pharmaceutical agents to injured tissues |
| US7601685B2 (en) | 1998-08-27 | 2009-10-13 | Eidgenossische Technische Hochschule Zurich | Growth factor modified protein matrices for tissue engineering |
| JP2001190280A (ja) * | 1999-02-19 | 2001-07-17 | Terumo Corp | コラーゲン結合性生理活性ポリペプチド |
| US20020102709A1 (en) * | 1999-02-19 | 2002-08-01 | Tetsuya Ishikawa | Collagen-binding physiologically active polypeptide |
| WO2000049159A1 (en) | 1999-02-19 | 2000-08-24 | Terumo Kabushiki Kaisha | Collagen-binding physiologically active polypeptide |
| US6908994B1 (en) | 1999-05-10 | 2005-06-21 | The Texas A&M University System | Collagen-binding proteins from enterococcal bacteria |
| US20050124537A1 (en) | 2000-04-27 | 2005-06-09 | Amgen Inc. | Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein |
| US20040053368A1 (en) | 2000-08-15 | 2004-03-18 | Tetsuya Ishikawa | Collagen-binding hybrid polypeptide |
| JP2002058485A (ja) | 2000-08-16 | 2002-02-26 | Terumo Corp | コラーゲン結合性を有する骨形成促進融合蛋白質 |
| US20020063621A1 (en) | 2000-09-01 | 2002-05-30 | Next Planet, Inc. | Method and apparatus for device communications |
| US6812217B2 (en) | 2000-12-04 | 2004-11-02 | Medtronic, Inc. | Medical device and methods of use |
| ES2301697T3 (es) | 2001-12-18 | 2008-07-01 | Eidgenossisch Technische Hochschule Zurich | Matrices de proteina modificada con factor de crecimiento para ingenieria de tejidos. |
| US7429383B2 (en) | 2002-07-25 | 2008-09-30 | The General Hospital Corporation | Parathyroid hormone receptor activation and hematopoietic progenitor cell expansion |
| US7060299B2 (en) | 2002-12-31 | 2006-06-13 | Battelle Memorial Institute | Biodegradable microparticles that stabilize and control the release of proteins |
| DE60307683T2 (de) | 2003-02-13 | 2008-05-15 | Synthes Gmbh | Injizierbare mischung zum ersatz von knochengewebe in situ |
| US20040220094A1 (en) | 2003-05-01 | 2004-11-04 | Skinner Keith K. | Inverse agonist and agonist peptides that stimulate/inhibit hair growth |
| JP4836798B2 (ja) | 2003-10-21 | 2011-12-14 | アイジーエフ オンコロジー エルエルシー | 癌を治療するための化合物および方法 |
| US20050119183A1 (en) * | 2003-11-12 | 2005-06-02 | Nps Allelix Corp. | Method for treating bone loss using parathyroid hormone |
| EP1557176A1 (en) | 2004-01-26 | 2005-07-27 | Ferring B.V. | Treatment of bone metastases by means of PTH receptor agonists |
| US20090005298A1 (en) | 2004-02-27 | 2009-01-01 | The University Of Western Ontario | Bone Sialoprotein Collagen-Binding Peptides |
| HUE055861T2 (hu) | 2004-04-21 | 2021-12-28 | Alexion Pharma Inc | Csontbejuttató konjugátumok és azok alkalmazási módszere fehérjék csonthoz kötéséhez |
| JP2008517917A (ja) | 2004-10-21 | 2008-05-29 | アイジーエフ オンコロジー エルエルシー | 癌を治療するための毒素および放射性核種結合igf−1受容体リガンド |
| WO2006073711A2 (en) * | 2005-01-06 | 2006-07-13 | Kuros Biosurgery Ag | Use of a matrix comprising a contrast agent in soft tissues |
| EP1970382B1 (en) | 2005-12-26 | 2011-06-29 | Yantai Zhenghai Bio-Technology Co., Ltd. | Activated collagen scaffold materials and their special fused active restoration factors |
| ES2675174T3 (es) | 2007-04-09 | 2018-07-09 | The Board Of Trustees Of The University Of Arkansas | Proteínas de fusión de un dominio de enlazamiento a colágeno y hormona paratiroidea |
| JP2010172247A (ja) | 2009-01-29 | 2010-08-12 | Kitasato Institute | 積層型高密度培養人工組織の製造方法及び積層型高密度培養人工組織 |
| JPWO2011142425A1 (ja) | 2010-05-12 | 2013-07-22 | 国立大学法人 香川大学 | 上皮層含有組織の再生材および再生評価方法 |
| US9248164B2 (en) | 2011-05-13 | 2016-02-02 | School Juridical Person Kitasato Institute | Growth factor anchoring type bone graft material, method for producing growth factor anchoring type bone graft material, kit for producing growth factor anchoring type bone graft material, and method for forming bone |
| US9579273B2 (en) | 2011-12-14 | 2017-02-28 | The Kitasato Institute | Delivery of therapeutic agents by a collagen binding protein |
| WO2013120060A1 (en) | 2012-02-09 | 2013-08-15 | The Board Of Trustees Of The University Of Arkansas | Delivery of therapeutic agents by a collagen binding protein |
-
2008
- 2008-04-09 ES ES16169069.8T patent/ES2675174T3/es active Active
- 2008-04-09 US US12/594,547 patent/US8450273B2/en active Active
- 2008-04-09 CA CA2930681A patent/CA2930681C/en active Active
- 2008-04-09 EP EP16169069.8A patent/EP3091075B1/en active Active
- 2008-04-09 JP JP2010503048A patent/JP5520811B2/ja active Active
- 2008-04-09 WO PCT/US2008/004589 patent/WO2008124166A2/en not_active Ceased
- 2008-04-09 ES ES08742686.2T patent/ES2583002T3/es active Active
- 2008-04-09 DK DK16169069.8T patent/DK3091075T3/en active
- 2008-04-09 DK DK08742686.2T patent/DK2155874T3/en active
- 2008-04-09 CA CA2683862A patent/CA2683862C/en active Active
- 2008-04-09 EP EP08742686.2A patent/EP2155874B1/en active Active
-
2013
- 2013-05-20 US US13/898,058 patent/US9062300B2/en active Active
- 2013-09-19 JP JP2013194484A patent/JP5821066B2/ja active Active
-
2015
- 2015-06-18 US US14/743,629 patent/US9528099B2/en active Active
- 2015-09-03 JP JP2015173678A patent/JP5989876B2/ja active Active
-
2016
- 2016-08-10 JP JP2016157345A patent/JP6366653B2/ja active Active
- 2016-12-22 US US15/387,817 patent/US10202434B2/en active Active
-
2019
- 2019-01-16 US US16/249,540 patent/US10358471B2/en active Active
- 2019-07-22 US US16/517,988 patent/US10519213B2/en active Active
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