JP2013544877A5 - - Google Patents
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- Publication number
- JP2013544877A5 JP2013544877A5 JP2013542630A JP2013542630A JP2013544877A5 JP 2013544877 A5 JP2013544877 A5 JP 2013544877A5 JP 2013542630 A JP2013542630 A JP 2013542630A JP 2013542630 A JP2013542630 A JP 2013542630A JP 2013544877 A5 JP2013544877 A5 JP 2013544877A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- thiadiazol
- pyridin
- carbon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CC([C+]N=C([C@@]([C@]([C@@](C)C([C@](C)CC(C[C@@](C)C([C@](C)C(OC1)=O)=O)OC)=O)[C@@]1(C)O1)C1=O)N)P* Chemical compound CC([C+]N=C([C@@]([C@]([C@@](C)C([C@](C)CC(C[C@@](C)C([C@](C)C(OC1)=O)=O)OC)=O)[C@@]1(C)O1)C1=O)N)P* 0.000 description 2
- MIZDRGWPIKBPQC-UHFFFAOYSA-N BrCc1nnc(-c2ncccn2)[s]1 Chemical compound BrCc1nnc(-c2ncccn2)[s]1 MIZDRGWPIKBPQC-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3352/MUM/2010 | 2010-12-09 | ||
| IN3352MU2010 | 2010-12-09 | ||
| PCT/IB2011/050464 WO2012076989A1 (en) | 2010-12-09 | 2011-02-03 | Ketolide compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015135252A Division JP6102991B2 (ja) | 2010-12-09 | 2015-07-06 | ケトライド化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013544877A JP2013544877A (ja) | 2013-12-19 |
| JP2013544877A5 true JP2013544877A5 (https=) | 2014-03-20 |
| JP5851516B2 JP5851516B2 (ja) | 2016-02-03 |
Family
ID=54259620
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013542630A Expired - Fee Related JP5851516B2 (ja) | 2010-12-09 | 2011-02-03 | ケトライド化合物 |
| JP2015135252A Expired - Fee Related JP6102991B2 (ja) | 2010-12-09 | 2015-07-06 | ケトライド化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015135252A Expired - Fee Related JP6102991B2 (ja) | 2010-12-09 | 2015-07-06 | ケトライド化合物 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US9175031B2 (https=) |
| EP (2) | EP3216798A3 (https=) |
| JP (2) | JP5851516B2 (https=) |
| KR (1) | KR101657751B1 (https=) |
| CN (2) | CN105669803A (https=) |
| AU (1) | AU2011340204B2 (https=) |
| BR (1) | BR112013014392B1 (https=) |
| CA (2) | CA2820451C (https=) |
| DK (1) | DK2673285T3 (https=) |
| ES (1) | ES2642287T3 (https=) |
| HU (1) | HUE036658T2 (https=) |
| MX (1) | MX348084B (https=) |
| NZ (1) | NZ623574A (https=) |
| PL (1) | PL2673285T3 (https=) |
| PT (1) | PT2673285T (https=) |
| RU (1) | RU2601550C2 (https=) |
| WO (1) | WO2012076989A1 (https=) |
| ZA (1) | ZA201304150B (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ587490A (en) * | 2010-08-20 | 2013-03-28 | Greentide Ltd | Anti-Microbial Compounds containing compounds with a sugar substituent |
| CN103619863B (zh) * | 2011-03-22 | 2016-03-16 | 沃克哈特有限公司 | 酮内酯化合物的制备方法 |
| US9346828B2 (en) * | 2013-06-07 | 2016-05-24 | Wisconsin Alumni Research Foundation | Forazolines, compositions thereof and uses thereof |
| ES2774510T3 (es) | 2015-07-27 | 2020-07-21 | Chong Kun Dang Pharmaceutical Corp | Derivados de 1,3,4-oxadiazol sulfamida como inhibidores de histona desacetilasa 6 y composición farmacéutica que comprende los mismos |
| FI3328843T3 (fi) | 2015-07-27 | 2023-01-31 | 1,3,4-oksadiatsolisulfonamidijohdannaisyhdisteitä histonideasetylaasi-6:n inhibiittoreina ja samaa käsittävä farmaseuttinen koostumus | |
| DK3330259T3 (da) * | 2015-07-27 | 2020-08-10 | Chong Kun Dang Pharmaceutical Corp | 1,3,4-oxadiazolamidderivativ-forbindelse som histondeacetylase-6-inhibitor og farmaceutisk sammensætning indeholdende denne |
| RU2709207C2 (ru) | 2015-08-04 | 2019-12-17 | Чонг Кун Данг Фармасьютикал Корп. | 1,3,4-оксадиазольные производные соединения в качестве ингибитора гистондеацетилазы 6 и фармацевтическая композиция, содержащая их |
| HRP20230201T1 (hr) | 2015-10-12 | 2023-03-31 | Chong Kun Dang Pharmaceutical Corp. | Oksadiazol aminski spojevi derivati kao inhibitor histonske deacetilaze 6 i farmaceutska kompozicija koja sadrži iste |
| WO2017122146A1 (en) * | 2016-01-12 | 2017-07-20 | Wockhardt Limited | Pharmaceutical compositions for the treatment of bacterial infections |
| CN108778255B (zh) * | 2016-01-12 | 2020-11-13 | 沃克哈特有限公司 | 药物组合物 |
| WO2017122127A1 (en) * | 2016-01-12 | 2017-07-20 | Wockhardt Limited | Pharmaceutical compositions |
| KR20190129863A (ko) * | 2017-03-16 | 2019-11-20 | 욱크하르트 리미티드 | 케톨라이드 화합물의 제조 방법 |
| KR102316234B1 (ko) | 2018-07-26 | 2021-10-22 | 주식회사 종근당 | 히스톤 탈아세틸화효소 6 억제제로서의 1,3,4-옥사다이아졸 유도체 화합물 및 이를 포함하는 약제학적 조성물 |
| AU2020284606B2 (en) | 2019-05-31 | 2023-01-19 | Chong Kun Dang Pharmaceutical Corp. | 1,3,4-oxadiazole homophthalimide derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same |
| EP4055011A1 (en) * | 2019-11-05 | 2022-09-14 | Dermira, Inc | Mrgprx2 antagonists and uses thereof |
| CN114845709B (zh) | 2019-11-05 | 2024-10-01 | 德米拉公司 | 用于治疗炎性病症的mrgprx2拮抗剂 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2473525A1 (fr) | 1980-01-11 | 1981-07-17 | Roussel Uclaf | Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments |
| US4331803A (en) | 1980-06-04 | 1982-05-25 | Taisho Pharmaceutical Co., Ltd. | Novel erythromycin compounds |
| SI8110592A8 (en) | 1981-03-06 | 1996-06-30 | Pliva Pharm & Chem Works | Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof |
| FR2719587B1 (fr) | 1994-05-03 | 1996-07-12 | Roussel Uclaf | Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments. |
| DE69733723T2 (de) | 1996-09-04 | 2006-04-20 | Abbott Laboratories, Abbott Park | 6-o-Substituierte Ketoliden mit antibakteriellen Wirkung |
| WO1999021870A1 (en) * | 1997-10-29 | 1999-05-06 | Taisho Pharmaceutical Co., Ltd. | Erythromycin a 11, 12-carbamate derivatives |
| HRP980189B1 (en) * | 1998-04-06 | 2004-04-30 | Pliva Pharm & Chem Works | Novel 15-membered lactams ketolides |
| FR2777282B1 (fr) * | 1998-04-08 | 2001-04-20 | Hoechst Marion Roussel Inc | Nouveaux derives de la 2-fluoro 3-de((2,6-dideoxy 3-c-methyl 3-0-methyl-alpha-l-ribohexopyranosyl) oxyl) 6-o-methyl 3-oxo erythromycine, leur procede de preparation et leur application a la synthese de principes actifs de medicaments |
| BR0113472A (pt) | 2000-08-22 | 2003-07-01 | Basilea Pharmaceutica Ag | Macrolìdeos com atividade antibacteriana |
| GB0031312D0 (en) | 2000-12-21 | 2001-02-07 | Glaxo Group Ltd | Macrolides |
| CN1492874A (zh) | 2000-12-21 | 2004-04-28 | 大环内酯 | |
| GB0127349D0 (en) | 2001-11-14 | 2002-01-02 | Glaxo Group Ltd | Macrolides |
| US6995143B2 (en) * | 2002-02-28 | 2006-02-07 | Basilea Pharmaceutica Ag | Macrolides with antibacterial activity |
| US6727229B2 (en) | 2002-08-19 | 2004-04-27 | Enanta Pharmaceuticals, Inc. | 11,12-substituted lactone ketolide derivatives having antibacterial activity |
| WO2004108744A2 (en) * | 2003-05-19 | 2004-12-16 | Prasad K Deshpande | Azalides and azaketolides having antimicrobial activity |
| JP2008508322A (ja) * | 2004-07-28 | 2008-03-21 | ランバクシー ラボラトリーズ リミテッド | 抗菌剤としてのケトライド誘導体 |
| WO2008023248A2 (en) * | 2006-08-24 | 2008-02-28 | Wockhardt Research Centre | Novel macrolides and ketolides having antimicrobial activity |
| ES2691252T3 (es) * | 2007-09-17 | 2018-11-26 | Enanta Pharmaceuticals, Inc. | Macrólidos de biarilo con puente en 6,11 |
| WO2009137787A1 (en) * | 2008-05-09 | 2009-11-12 | Enanta Pharmaceuticals, Inc. | Processes for the preparation of 2-fluoro 6-11 bicyclic erythromycin derivatives |
| BRPI1011959A2 (pt) * | 2009-05-27 | 2016-04-26 | Wockhardt Research Center | compostos de cetolídeo tendo atividade antimicrobiana. |
-
2011
- 2011-02-03 WO PCT/IB2011/050464 patent/WO2012076989A1/en not_active Ceased
- 2011-02-03 PT PT117080929T patent/PT2673285T/pt unknown
- 2011-02-03 KR KR1020137016527A patent/KR101657751B1/ko not_active Expired - Fee Related
- 2011-02-03 NZ NZ623574A patent/NZ623574A/en not_active IP Right Cessation
- 2011-02-03 PL PL11708092T patent/PL2673285T3/pl unknown
- 2011-02-03 RU RU2013131234/04A patent/RU2601550C2/ru active
- 2011-02-03 ES ES11708092.9T patent/ES2642287T3/es active Active
- 2011-02-03 AU AU2011340204A patent/AU2011340204B2/en not_active Ceased
- 2011-02-03 JP JP2013542630A patent/JP5851516B2/ja not_active Expired - Fee Related
- 2011-02-03 HU HUE11708092A patent/HUE036658T2/hu unknown
- 2011-02-03 CN CN201610004950.0A patent/CN105669803A/zh active Pending
- 2011-02-03 DK DK11708092.9T patent/DK2673285T3/en active
- 2011-02-03 MX MX2013006461A patent/MX348084B/es active IP Right Grant
- 2011-02-03 CA CA2820451A patent/CA2820451C/en not_active Expired - Fee Related
- 2011-02-03 EP EP17164547.6A patent/EP3216798A3/en not_active Withdrawn
- 2011-02-03 BR BR112013014392-4A patent/BR112013014392B1/pt active IP Right Grant
- 2011-02-03 US US13/991,762 patent/US9175031B2/en active Active
- 2011-02-03 CN CN201180066627.1A patent/CN103384676B/zh active Active
- 2011-02-03 CA CA2964104A patent/CA2964104A1/en not_active Abandoned
- 2011-02-03 EP EP11708092.9A patent/EP2673285B1/en active Active
-
2013
- 2013-06-06 ZA ZA2013/04150A patent/ZA201304150B/en unknown
-
2015
- 2015-07-06 JP JP2015135252A patent/JP6102991B2/ja not_active Expired - Fee Related
- 2015-09-19 US US14/859,254 patent/US20160083412A1/en not_active Abandoned
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