JP2013544494A5 - - Google Patents

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Publication number
JP2013544494A5
JP2013544494A5 JP2013527595A JP2013527595A JP2013544494A5 JP 2013544494 A5 JP2013544494 A5 JP 2013544494A5 JP 2013527595 A JP2013527595 A JP 2013527595A JP 2013527595 A JP2013527595 A JP 2013527595A JP 2013544494 A5 JP2013544494 A5 JP 2013544494A5
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JP
Japan
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seq
cells
ion channel
retinal
photoinduced
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JP2013527595A
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English (en)
Japanese (ja)
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JP5933556B2 (ja
JP2013544494A (ja
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Priority claimed from PCT/EP2011/065510 external-priority patent/WO2012032103A1/en
Publication of JP2013544494A publication Critical patent/JP2013544494A/ja
Publication of JP2013544494A5 publication Critical patent/JP2013544494A5/ja
Application granted granted Critical
Publication of JP5933556B2 publication Critical patent/JP5933556B2/ja
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JP2013527595A 2010-09-08 2011-09-08 変異チャネルロドプシン２ Active JP5933556B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US38079310P 2010-09-08 2010-09-08
EP10175832 2010-09-08
US61/380,793 2010-09-08
EP10175832.4 2010-09-08
PCT/EP2011/065510 WO2012032103A1 (en) 2010-09-08 2011-09-08 Mutant channelrhodopsin 2

Publications (3)

Publication Number Publication Date
JP2013544494A JP2013544494A (ja) 2013-12-19
JP2013544494A5 true JP2013544494A5 (cg-RX-API-DMAC10.html) 2014-10-02
JP5933556B2 JP5933556B2 (ja) 2016-06-15

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JP2013527595A Active JP5933556B2 (ja) 2010-09-08 2011-09-08 変異チャネルロドプシン２

Country Status (20)

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US (1) US8748578B2 (cg-RX-API-DMAC10.html)
EP (1) EP2614079B1 (cg-RX-API-DMAC10.html)
JP (1) JP5933556B2 (cg-RX-API-DMAC10.html)
KR (1) KR101945962B1 (cg-RX-API-DMAC10.html)
CN (1) CN103261219B (cg-RX-API-DMAC10.html)
AU (1) AU2011298745B2 (cg-RX-API-DMAC10.html)
BR (1) BR112013005634A2 (cg-RX-API-DMAC10.html)
CA (1) CA2810757C (cg-RX-API-DMAC10.html)
DK (1) DK2614079T3 (cg-RX-API-DMAC10.html)
ES (1) ES2545992T3 (cg-RX-API-DMAC10.html)
HR (1) HRP20150846T1 (cg-RX-API-DMAC10.html)
HU (1) HUE025952T2 (cg-RX-API-DMAC10.html)
IL (1) IL225060A (cg-RX-API-DMAC10.html)
MX (1) MX347453B (cg-RX-API-DMAC10.html)
PL (1) PL2614079T3 (cg-RX-API-DMAC10.html)
PT (1) PT2614079E (cg-RX-API-DMAC10.html)
RU (1) RU2595384C2 (cg-RX-API-DMAC10.html)
SG (1) SG188409A1 (cg-RX-API-DMAC10.html)
SI (1) SI2614079T1 (cg-RX-API-DMAC10.html)
WO (1) WO2012032103A1 (cg-RX-API-DMAC10.html)

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US9238150B2 (en) 2005-07-22 2016-01-19 The Board Of Trustees Of The Leland Stanford Junior University Optical tissue interface method and apparatus for stimulating cells
US20090093403A1 (en) 2007-03-01 2009-04-09 Feng Zhang Systems, methods and compositions for optical stimulation of target cells
US8926959B2 (en) 2005-07-22 2015-01-06 The Board Of Trustees Of The Leland Stanford Junior University System for optical stimulation of target cells
US10052497B2 (en) 2005-07-22 2018-08-21 The Board Of Trustees Of The Leland Stanford Junior University System for optical stimulation of target cells
JP2009502140A (ja) 2005-07-22 2009-01-29 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 光活性化陽イオンチャネルおよびその使用
US9274099B2 (en) 2005-07-22 2016-03-01 The Board Of Trustees Of The Leland Stanford Junior University Screening test drugs to identify their effects on cell membrane voltage-gated ion channel
US8470790B2 (en) 2006-05-04 2013-06-25 Wayne State University Restoration of visual responses by in vivo delivery of rhodopsin nucleic acids
US8398692B2 (en) 2007-01-10 2013-03-19 The Board Of Trustees Of The Leland Stanford Junior University System for optical stimulation of target cells
US8401609B2 (en) 2007-02-14 2013-03-19 The Board Of Trustees Of The Leland Stanford Junior University System, method and applications involving identification of biological circuits such as neurological characteristics
US10434327B2 (en) 2007-10-31 2019-10-08 The Board Of Trustees Of The Leland Stanford Junior University Implantable optical stimulators
US10035027B2 (en) 2007-10-31 2018-07-31 The Board Of Trustees Of The Leland Stanford Junior University Device and method for ultrasonic neuromodulation via stereotactic frame based technique
ES2701349T3 (es) 2008-04-23 2019-02-21 Univ Leland Stanford Junior Sistemas, métodos y composiciones para la estimulación óptica de células diana
EP2294208B1 (en) 2008-05-29 2013-05-08 The Board of Trustees of The Leland Stanford Junior University Cell line, system and method for optical control of secondary messengers
EP2303405A4 (en) 2008-06-17 2017-12-27 The Board of Trustees of the Leland Stanford Junior University Apparatus and methods for controlling cellular development
JP2011525130A (ja) 2008-06-17 2011-09-15 ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティ 光伝送素子を用いた標的細胞の光刺激のための方法、システム、および装置
WO2010006049A1 (en) 2008-07-08 2010-01-14 The Board Of Trustees Of The Leland Stanford Junior University Materials and approaches for optical stimulation of the peripheral nervous system
NZ602416A (en) 2008-11-14 2014-08-29 Univ Leland Stanford Junior Optically-based stimulation of target cells and modifications thereto
EP3399024A1 (en) 2010-03-17 2018-11-07 The Board of Trustees of The Leland Stanford Junior University Light-sensitive ion-passing molecules
WO2011140279A1 (en) 2010-05-04 2011-11-10 Wayne State University Aav-mediated subcellular targeting of heterologous rhodopsins in retinal ganglion cells
CN103384469B (zh) 2010-11-05 2016-06-15 斯坦福大学托管董事会 光控cns功能障碍
US10086012B2 (en) 2010-11-05 2018-10-02 The Board Of Trustees Of The Leland Stanford Junior University Control and characterization of memory function
ES2625179T3 (es) 2010-11-05 2017-07-18 The Board Of Trustees Of The Leland Stanford Junior University Control optogenético de comportamientos relacionados con la recompensa
CN106422081B (zh) 2010-11-05 2019-06-21 斯坦福大学托管董事会 用于光遗传学方法的光的上转换
US10568307B2 (en) 2010-11-05 2020-02-25 The Board Of Trustees Of The Leland Stanford Junior University Stabilized step function opsin proteins and methods of using the same
EP3486253A1 (en) 2010-11-05 2019-05-22 The Board of Trustees of The Leland Stanford Junior University Light-activated chimeric opsins and methods of using the same
US8696722B2 (en) 2010-11-22 2014-04-15 The Board Of Trustees Of The Leland Stanford Junior University Optogenetic magnetic resonance imaging
CA2859364C (en) 2011-12-16 2019-05-07 The Board Of Trustees Of The Leland Stanford Junior University Opsin polypeptides and methods of use thereof
ES2628006T3 (es) 2012-02-21 2017-08-01 Circuit Therapeutics, Inc. Composiciones para el tratamiento de trastornos neurogénicos del suelo pélvico
EA201491643A1 (ru) 2012-03-05 2015-02-27 Уэйн Стейт Юниверсити Идентификация мутаций канал-опсина-2 (chop2) и способы применения
ES2742492T3 (es) 2013-03-15 2020-02-14 Univ Leland Stanford Junior Control optogenético del estado conductual
US9636380B2 (en) 2013-03-15 2017-05-02 The Board Of Trustees Of The Leland Stanford Junior University Optogenetic control of inputs to the ventral tegmental area
US10220092B2 (en) 2013-04-29 2019-03-05 The Board Of Trustees Of The Leland Stanford Junior University Devices, systems and methods for optogenetic modulation of action potentials in target cells
JP6621747B2 (ja) 2013-08-14 2019-12-18 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 疼痛を制御するための組成物及び方法
JP6118239B2 (ja) * 2013-11-29 2017-04-19 雅敏 堀 害虫の防除方法及び防除装置
WO2015167639A1 (en) * 2014-02-07 2015-11-05 Massachusetts Institute Of Technology Blue light-activated ion channel molecules and uses thereof
US10047130B2 (en) 2014-03-18 2018-08-14 Washington University Methods and compositions for red-shifted chromophore substitution for optogenetic applications
WO2015161308A1 (en) * 2014-04-18 2015-10-22 Massachusetts Institute Of Technology Mutant channelrhodopsins with altered ion selectivity
US10568516B2 (en) 2015-06-22 2020-02-25 The Board Of Trustees Of The Leland Stanford Junior University Methods and devices for imaging and/or optogenetic control of light-responsive neurons
US11384132B2 (en) 2016-06-03 2022-07-12 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Mutant light-inducible ion channel of chrimson
EP3464341A1 (en) * 2016-06-03 2019-04-10 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Mutant light-inducible ion channel of channelrhodopsin
WO2018044912A1 (en) 2016-08-29 2018-03-08 Wayne State University Identification of mutations in channelopsin variants having improved light sensitivity and methods of use thereof
EP3535282A4 (en) * 2016-11-06 2020-04-08 Nanoscope Technologies LLC OPTOGENETIC MODULATION BY OPSINS WITH MULTIPLE CHARACTERISTICS FOR RESTORATION OF VISION AND OTHER ASSOCIATED APPLICATIONS
US11294165B2 (en) 2017-03-30 2022-04-05 The Board Of Trustees Of The Leland Stanford Junior University Modular, electro-optical device for increasing the imaging field of view using time-sequential capture
US20200115419A1 (en) * 2017-04-12 2020-04-16 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. New optogenetic tool
CN110483645B (zh) * 2018-05-14 2023-05-12 郑州大学第一附属医院 线粒体定位质子泵型视紫红质、其突变蛋白及其应用
JP7242851B2 (ja) * 2018-07-26 2023-03-20 カウンシル・オブ・サイエンティフィック・アンド・インダストリアル・リサーチ・アン・インディアン・レジスタード・ボディ・インコーポレイテッド・アンダー・ザ・レジストレーション・オブ・ソサエティーズ・アクト・(アクト・21・オブ・1860) 子宮頸がんのグレード検出のためのスクリーニングキットおよびその調製方法
CN112689675B (zh) * 2018-09-14 2023-09-19 国立大学法人名古屋工业大学 光响应性蛋白及其应用
US20230104240A1 (en) * 2020-03-13 2023-04-06 Nagoya Institute Of Technology Photoresponsive protein for color recognition and use thereof
WO2022176754A1 (ja) * 2021-02-18 2022-08-25 国立大学法人名古屋工業大学 青色光もしくは藍色光応答性タンパク質及びその利用
EP4223768B1 (en) * 2022-02-04 2026-05-06 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin Novel mutant bacteriorhodopsin-like-channelrhodopsin ion channel
WO2024092248A1 (en) * 2022-10-28 2024-05-02 The Board Of Trustees Of The Leland Stanford Junior University Enhanced light gated potassium selective channelrhodopsin

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EP2112501A1 (de) 1998-02-05 2009-10-28 Novartis Ag Verfahren und Vorrichtung zur Lumineszenzmessung
DE10216005A1 (de) * 2002-04-11 2003-10-30 Max Planck Gesellschaft Verwendung von biologischen Photorezeptoren als direkt lichtgesteuerte Ionenkanäle
US8470790B2 (en) * 2006-05-04 2013-06-25 Wayne State University Restoration of visual responses by in vivo delivery of rhodopsin nucleic acids
DE102008020152B4 (de) * 2008-04-22 2012-04-05 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Verwendung von biologischen Photorezeptoren als direkt lichtgesteuerte Ionenkanäle
NZ602416A (en) * 2008-11-14 2014-08-29 Univ Leland Stanford Junior Optically-based stimulation of target cells and modifications thereto

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