JP2013542179A5 - - Google Patents

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Publication number
JP2013542179A5
JP2013542179A5 JP2013527063A JP2013527063A JP2013542179A5 JP 2013542179 A5 JP2013542179 A5 JP 2013542179A5 JP 2013527063 A JP2013527063 A JP 2013527063A JP 2013527063 A JP2013527063 A JP 2013527063A JP 2013542179 A5 JP2013542179 A5 JP 2013542179A5
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JP
Japan
Prior art keywords
medicament
tgf
antibody
seq
antagonist
Prior art date
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Application number
JP2013527063A
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English (en)
Japanese (ja)
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JP6377348B2 (ja
JP2013542179A (ja
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Priority claimed from PCT/US2011/001536 external-priority patent/WO2012030394A1/en
Publication of JP2013542179A publication Critical patent/JP2013542179A/ja
Publication of JP2013542179A5 publication Critical patent/JP2013542179A5/ja
Application granted granted Critical
Publication of JP6377348B2 publication Critical patent/JP6377348B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2013527063A 2010-09-01 2011-09-01 TGF−βアンタゴニストを使用する心筋梗塞の処置 Expired - Fee Related JP6377348B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37931510P 2010-09-01 2010-09-01
US61/379,315 2010-09-01
PCT/US2011/001536 WO2012030394A1 (en) 2010-09-01 2011-09-01 Treatment of myocardial infarction using tgf - beta antagonists

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017083499A Division JP2017193543A (ja) 2010-09-01 2017-04-20 TGF−βアンタゴニストを使用する心筋梗塞の処置

Publications (3)

Publication Number Publication Date
JP2013542179A JP2013542179A (ja) 2013-11-21
JP2013542179A5 true JP2013542179A5 (https=) 2014-10-09
JP6377348B2 JP6377348B2 (ja) 2018-08-22

Family

ID=44654454

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2013527063A Expired - Fee Related JP6377348B2 (ja) 2010-09-01 2011-09-01 TGF−βアンタゴニストを使用する心筋梗塞の処置
JP2017083499A Pending JP2017193543A (ja) 2010-09-01 2017-04-20 TGF−βアンタゴニストを使用する心筋梗塞の処置

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2017083499A Pending JP2017193543A (ja) 2010-09-01 2017-04-20 TGF−βアンタゴニストを使用する心筋梗塞の処置

Country Status (19)

Country Link
US (2) US20130330352A1 (https=)
EP (1) EP2611831B1 (https=)
JP (2) JP6377348B2 (https=)
KR (1) KR101939965B1 (https=)
CN (1) CN103201292B (https=)
BR (1) BR112013004850B1 (https=)
CA (1) CA2809568C (https=)
CL (1) CL2013000586A1 (https=)
ES (1) ES2715177T3 (https=)
IL (1) IL225018A (https=)
MX (1) MX354535B (https=)
MY (1) MY165160A (https=)
NZ (2) NZ608813A (https=)
PH (1) PH12013500411A1 (https=)
PL (1) PL2611831T3 (https=)
RU (1) RU2637088C2 (https=)
SG (2) SG187953A1 (https=)
TR (1) TR201903101T4 (https=)
WO (1) WO2012030394A1 (https=)

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Publication number Priority date Publication date Assignee Title
BRPI1008628A2 (pt) * 2009-02-18 2016-03-01 Cormatrix Cardiovascular Inc método de tratamento ou prevenção de arritmia cardíaca em um indivíduo
PT2971048T (pt) * 2013-03-11 2019-02-06 Genzyme Corp Anticorpos anti-tgf-beta manipulados e fragmentos de ligação a antigénios
CA2921805C (en) 2013-08-22 2023-03-07 Acceleron Pharma, Inc. Tgf-beta receptor type ii variants and uses thereof
EP3234120B1 (en) 2014-12-15 2025-09-03 The Regents of the University of California Cytotoxic molecules responsive to intracellular ligands for selective t cell mediated killing
EP4400516A1 (en) 2014-12-15 2024-07-17 The Regents of the University of California Bispecific or-gate chimeric antigen receptor responsive to cd19 and cd20
HK1256638A1 (zh) 2015-08-04 2019-09-27 Acceleron Pharma Inc. 用於治疗骨髓增生性病症的方法
DK3368571T5 (da) 2015-10-30 2024-09-30 Univ California Transformerende, vækstfaktor-beta-responsive polypeptider og fremgangsmåder til anvendelse deraf
TW201726744A (zh) 2016-01-11 2017-08-01 奧托德里克有限公司 用於檢測奧美沙坦(olmesartan)及改善治療高血壓之遵從性的組成物、裝置及方法
US20170218040A1 (en) * 2016-02-02 2017-08-03 Julio A. Camarero Palao Proteolically resistant cyclotides with angiotensin 1-7 like activity
JP2019533003A (ja) * 2016-08-11 2019-11-14 プレシセラ,インコーポレイテッド TGF−βアンタゴニストコンジュゲート
LT3628049T (lt) 2017-05-04 2023-08-25 Acceleron Pharma Inc. Tgf-beta ii tipo receptoriaus sulieti baltymai ir jų panaudojimo būdai
AU2021339468A1 (en) * 2020-09-10 2023-03-30 Implicit Bioscience Limited Therapeutic methods and agents for the treatment of myocardial infarction
US20250034212A1 (en) 2021-09-30 2025-01-30 Peptidream Inc. Peptide

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
JPS61134325A (ja) 1984-12-04 1986-06-21 Teijin Ltd ハイブリツド抗体遺伝子の発現方法
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5571714A (en) 1988-12-22 1996-11-05 Celtrix Pharmaceuticals, Inc. Monoclonal antibodies which bind both transforming growth factors β1 and β2 and methods of use
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
ATE199392T1 (de) 1992-12-04 2001-03-15 Medical Res Council Multivalente und multispezifische bindungsproteine, deren herstellung und verwendung
DE69941267D1 (de) 1998-12-10 2009-09-24 Bristol Myers Squibb Co Proteingerüste für antikörper-nachahmer und andere bindende proteine
US7763580B2 (en) * 1999-01-05 2010-07-27 University Of Utah Research Foundation Methods for treating conditions associated with the accumulation of excess extracellular matrix
CN1961003B (zh) * 2004-03-31 2013-03-27 健泰科生物技术公司 人源化抗TGF-β抗体
WO2006083779A2 (en) 2005-01-31 2006-08-10 Mylan Laboratories, Inc. Pharmaceutical composition comprising hydroxylated nebivolol
WO2006086469A2 (en) * 2005-02-08 2006-08-17 Genzyme Corporation Antibodies to tgfbeta
AU2010206543A1 (en) * 2009-01-26 2011-07-07 Intermune, Inc. Methods for treating acute myocardial infarctions and associated disorders
ITMI20110376A1 (it) 2011-03-10 2012-09-11 Wilic Sarl Aerogeneratore raffreddato a fluido

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