JP2013542179A5 - - Google Patents

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Publication number
JP2013542179A5
JP2013542179A5 JP2013527063A JP2013527063A JP2013542179A5 JP 2013542179 A5 JP2013542179 A5 JP 2013542179A5 JP 2013527063 A JP2013527063 A JP 2013527063A JP 2013527063 A JP2013527063 A JP 2013527063A JP 2013542179 A5 JP2013542179 A5 JP 2013542179A5
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JP
Japan
Prior art keywords
medicament
tgf
antibody
seq
antagonist
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2013527063A
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English (en)
Japanese (ja)
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JP6377348B2 (ja
JP2013542179A (ja
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Publication date
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Priority claimed from PCT/US2011/001536 external-priority patent/WO2012030394A1/en
Publication of JP2013542179A publication Critical patent/JP2013542179A/ja
Publication of JP2013542179A5 publication Critical patent/JP2013542179A5/ja
Application granted granted Critical
Publication of JP6377348B2 publication Critical patent/JP6377348B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2013527063A 2010-09-01 2011-09-01 TGF−βアンタゴニストを使用する心筋梗塞の処置 Expired - Fee Related JP6377348B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37931510P 2010-09-01 2010-09-01
US61/379,315 2010-09-01
PCT/US2011/001536 WO2012030394A1 (en) 2010-09-01 2011-09-01 Treatment of myocardial infarction using tgf - beta antagonists

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017083499A Division JP2017193543A (ja) 2010-09-01 2017-04-20 TGF−βアンタゴニストを使用する心筋梗塞の処置

Publications (3)

Publication Number Publication Date
JP2013542179A JP2013542179A (ja) 2013-11-21
JP2013542179A5 true JP2013542179A5 (https=) 2014-10-09
JP6377348B2 JP6377348B2 (ja) 2018-08-22

Family

ID=44654454

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2013527063A Expired - Fee Related JP6377348B2 (ja) 2010-09-01 2011-09-01 TGF−βアンタゴニストを使用する心筋梗塞の処置
JP2017083499A Pending JP2017193543A (ja) 2010-09-01 2017-04-20 TGF−βアンタゴニストを使用する心筋梗塞の処置

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2017083499A Pending JP2017193543A (ja) 2010-09-01 2017-04-20 TGF−βアンタゴニストを使用する心筋梗塞の処置

Country Status (19)

Country Link
US (2) US20130330352A1 (https=)
EP (1) EP2611831B1 (https=)
JP (2) JP6377348B2 (https=)
KR (1) KR101939965B1 (https=)
CN (1) CN103201292B (https=)
BR (1) BR112013004850B1 (https=)
CA (1) CA2809568C (https=)
CL (1) CL2013000586A1 (https=)
ES (1) ES2715177T3 (https=)
IL (1) IL225018A (https=)
MX (1) MX354535B (https=)
MY (1) MY165160A (https=)
NZ (2) NZ624382A (https=)
PH (1) PH12013500411A1 (https=)
PL (1) PL2611831T3 (https=)
RU (1) RU2637088C2 (https=)
SG (2) SG187953A1 (https=)
TR (1) TR201903101T4 (https=)
WO (1) WO2012030394A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI1008628A2 (pt) * 2009-02-18 2016-03-01 Cormatrix Cardiovascular Inc método de tratamento ou prevenção de arritmia cardíaca em um indivíduo
LT2971048T (lt) * 2013-03-11 2019-02-25 Genzyme Corporation Inžineriniu būdu gauti anti-tgf-beta antikūnai ir antigeną surišantys fragmentai
HK1225740A1 (zh) 2013-08-22 2017-09-15 Acceleron Pharma Inc. TGF-β受体II型变体及其用途
FI3240805T3 (fi) 2014-12-15 2025-02-17 Univ California Cd19- ja cd20-vasteellinen bispesifinen tai-veräjän kimeerinen antigeenireseptori
EP3234120B1 (en) 2014-12-15 2025-09-03 The Regents of the University of California Cytotoxic molecules responsive to intracellular ligands for selective t cell mediated killing
CN108348578B (zh) 2015-08-04 2022-08-09 阿塞勒隆制药公司 用于治疗骨髓增生性病症的方法
PL3368571T3 (pl) * 2015-10-30 2023-05-02 The Regents Of The University Of California Polipeptydy odpowiadające na transformujący czynnik wzrostu beta i sposoby ich zastosowania
US9989543B2 (en) 2016-01-11 2018-06-05 Autotelic, Llc Composition, device, and method for detecting olmesartan and improving compliance in treating hypertension
US20170218040A1 (en) * 2016-02-02 2017-08-03 Julio A. Camarero Palao Proteolically resistant cyclotides with angiotensin 1-7 like activity
AU2017310344A1 (en) * 2016-08-11 2019-03-07 Precithera, Inc. TGF-β antagonist conjugates
ES2948647T3 (es) 2017-05-04 2023-09-15 Acceleron Pharma Inc Proteínas de fusión del receptor TGF-beta tipo II y usos de las mismas
CN116367858A (zh) * 2020-09-10 2023-06-30 隐式生物科技有限公司 用于治疗心肌梗塞的治疗方法和试剂
WO2023054712A1 (ja) 2021-09-30 2023-04-06 ペプチドリーム株式会社 ペプチド

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
JPS61134325A (ja) 1984-12-04 1986-06-21 Teijin Ltd ハイブリツド抗体遺伝子の発現方法
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5571714A (en) 1988-12-22 1996-11-05 Celtrix Pharmaceuticals, Inc. Monoclonal antibodies which bind both transforming growth factors β1 and β2 and methods of use
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
ES2156149T3 (es) 1992-12-04 2001-06-16 Medical Res Council Proteinas de union multivalente y multiespecificas, su fabricacion y su uso.
DK1137941T4 (da) 1998-12-10 2014-01-06 Brystol Myers Squibb Company Protein-scaffolds til antistof-mimetika og andre bindingsproteiner
US7763580B2 (en) * 1999-01-05 2010-07-27 University Of Utah Research Foundation Methods for treating conditions associated with the accumulation of excess extracellular matrix
EP1740615B1 (en) 2004-03-31 2014-11-05 Genentech, Inc. Humanized anti-tgf-beta antibodies
JP2008528626A (ja) 2005-01-31 2008-07-31 マイラン ラボラトリーズ インク. ヒドロキシル化されたネビボロールを含む薬学的組成物
TR201901929T4 (tr) 2005-02-08 2019-03-21 Genzyme Corp TGFBeta'ya antikorlar.
AP2011005824A0 (en) * 2009-01-26 2011-08-31 Intermune Inc Methods for treating acute myocardial infarctions and associated disorders.
ITMI20110376A1 (it) 2011-03-10 2012-09-11 Wilic Sarl Aerogeneratore raffreddato a fluido

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