JP2013541697A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013541697A5 JP2013541697A5 JP2013525961A JP2013525961A JP2013541697A5 JP 2013541697 A5 JP2013541697 A5 JP 2013541697A5 JP 2013525961 A JP2013525961 A JP 2013525961A JP 2013525961 A JP2013525961 A JP 2013525961A JP 2013541697 A5 JP2013541697 A5 JP 2013541697A5
- Authority
- JP
- Japan
- Prior art keywords
- individual
- biomarker
- pancreatic cancer
- information corresponding
- pancreatic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 37
- 239000000090 biomarker Substances 0.000 claims 35
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 21
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 21
- 201000002528 pancreatic cancer Diseases 0.000 claims 21
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 21
- 238000004458 analytical method Methods 0.000 claims 12
- 239000012472 biological sample Substances 0.000 claims 7
- 238000000338 in vitro Methods 0.000 claims 5
- 108090000623 proteins and genes Proteins 0.000 claims 5
- 102000004169 proteins and genes Human genes 0.000 claims 5
- 108091023037 Aptamer Proteins 0.000 claims 4
- 239000003153 chemical reaction reagent Substances 0.000 claims 4
- 230000002380 cytological effect Effects 0.000 claims 4
- 210000004923 pancreatic tissue Anatomy 0.000 claims 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 3
- 230000000391 smoking effect Effects 0.000 claims 3
- 206010000077 Abdominal mass Diseases 0.000 claims 2
- 102100022524 Alpha-1-antichymotrypsin Human genes 0.000 claims 2
- 102100036850 C-C motif chemokine 23 Human genes 0.000 claims 2
- 102100021633 Cathepsin B Human genes 0.000 claims 2
- 102100040898 Growth/differentiation factor 11 Human genes 0.000 claims 2
- 102100036284 Hepcidin Human genes 0.000 claims 2
- 101000678026 Homo sapiens Alpha-1-antichymotrypsin Proteins 0.000 claims 2
- 101000713081 Homo sapiens C-C motif chemokine 23 Proteins 0.000 claims 2
- 101000898449 Homo sapiens Cathepsin B Proteins 0.000 claims 2
- 101000893545 Homo sapiens Growth/differentiation factor 11 Proteins 0.000 claims 2
- 101001021253 Homo sapiens Hepcidin Proteins 0.000 claims 2
- 101000990912 Homo sapiens Matrilysin Proteins 0.000 claims 2
- 101001091365 Homo sapiens Plasma kallikrein Proteins 0.000 claims 2
- 101000605534 Homo sapiens Prostate-specific antigen Proteins 0.000 claims 2
- 101000633617 Homo sapiens Thrombospondin-4 Proteins 0.000 claims 2
- 102100030417 Matrilysin Human genes 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 102100034869 Plasma kallikrein Human genes 0.000 claims 2
- 102100029219 Thrombospondin-4 Human genes 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 238000003745 diagnosis Methods 0.000 claims 2
- 238000003018 immunoassay Methods 0.000 claims 2
- 210000001819 pancreatic juice Anatomy 0.000 claims 2
- 210000002381 plasma Anatomy 0.000 claims 2
- 210000002966 serum Anatomy 0.000 claims 2
- 208000018522 Gastrointestinal disease Diseases 0.000 claims 1
- 206010049082 Pancreatic mass Diseases 0.000 claims 1
- 206010033645 Pancreatitis Diseases 0.000 claims 1
- 230000000711 cancerogenic effect Effects 0.000 claims 1
- 231100000357 carcinogen Toxicity 0.000 claims 1
- 239000003183 carcinogenic agent Substances 0.000 claims 1
- 238000003748 differential diagnosis Methods 0.000 claims 1
- 230000014509 gene expression Effects 0.000 claims 1
- 230000002068 genetic effect Effects 0.000 claims 1
- 238000009533 lab test Methods 0.000 claims 1
- 239000003550 marker Substances 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37368710P | 2010-08-13 | 2010-08-13 | |
| US61/373,687 | 2010-08-13 | ||
| US41868910P | 2010-12-01 | 2010-12-01 | |
| US61/418,689 | 2010-12-01 | ||
| US201161482347P | 2011-05-04 | 2011-05-04 | |
| US201161482480P | 2011-05-04 | 2011-05-04 | |
| US61/482,480 | 2011-05-04 | ||
| US61/482,347 | 2011-05-04 | ||
| PCT/US2011/047570 WO2012021795A2 (en) | 2010-08-13 | 2011-08-12 | Pancreatic cancer biomarkers and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013541697A JP2013541697A (ja) | 2013-11-14 |
| JP2013541697A5 true JP2013541697A5 (https=) | 2014-09-18 |
| JP5931874B2 JP5931874B2 (ja) | 2016-06-08 |
Family
ID=45565264
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013525961A Expired - Fee Related JP5931874B2 (ja) | 2010-08-13 | 2011-08-12 | 膵癌バイオマーカーおよびその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US20120040861A1 (https=) |
| EP (1) | EP2603622A4 (https=) |
| JP (1) | JP5931874B2 (https=) |
| KR (1) | KR101857462B1 (https=) |
| CN (2) | CN103415624B (https=) |
| AU (3) | AU2011289284B2 (https=) |
| BR (1) | BR112013003391B8 (https=) |
| CA (1) | CA2804857C (https=) |
| IL (1) | IL224014A (https=) |
| MX (2) | MX350533B (https=) |
| SG (3) | SG187045A1 (https=) |
| WO (1) | WO2012021795A2 (https=) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10359425B2 (en) * | 2008-09-09 | 2019-07-23 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| WO2012006632A2 (en) | 2010-07-09 | 2012-01-12 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| SG187045A1 (en) | 2010-08-13 | 2013-02-28 | Somalogic Inc | Pancreatic cancer biomarkers and uses thereof |
| NL2009015C2 (en) * | 2012-04-10 | 2013-10-15 | Biosparq B V | Method for classification of a sample on the basis of spectral data, method for creating a database and method for using this database, and corresponding computer program, data storage medium and system. |
| HK1214652A1 (zh) * | 2013-03-13 | 2016-07-29 | 克里蒂科斯有限责任公司 | 用於检测胰腺癌的方法和组合物 |
| US20140272963A1 (en) * | 2013-03-14 | 2014-09-18 | Abbott Molecular Inc. | Cell preparations and cell supports and their use in theranosis |
| CN103324846A (zh) * | 2013-06-13 | 2013-09-25 | 浙江加州国际纳米技术研究院绍兴分院 | 结直肠癌症治疗预后生物标记物的筛选方法 |
| CN103310105A (zh) * | 2013-06-13 | 2013-09-18 | 浙江加州国际纳米技术研究院绍兴分院 | 筛选非小细胞肺癌治疗疗效生物标记物的方法 |
| JP6652916B2 (ja) * | 2013-06-20 | 2020-02-26 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | 膵臓がんを診断するための方法 |
| KR101594980B1 (ko) * | 2013-10-31 | 2016-02-17 | 에스케이텔레콤 주식회사 | 췌장암 진단용 조성물 및 이를 이용한 췌장암 진단방법 |
| KR101594981B1 (ko) * | 2013-10-31 | 2016-02-17 | 에스케이텔레콤 주식회사 | 췌장암 진단용 조성물 및 이를 이용한 췌장암 진단방법 |
| CN105408751A (zh) | 2013-10-31 | 2016-03-16 | Sk电信有限公社 | 用于诊断胰腺癌的组合物以及使用该组合物诊断胰腺癌的方法 |
| KR20150129932A (ko) * | 2014-05-12 | 2015-11-23 | 연세대학교 산학협력단 | 보체인자 b 단백질에 특이적으로 결합하는 항체를 포함하는 췌장암 진단용 키트 |
| US9506925B2 (en) | 2014-07-02 | 2016-11-29 | Dragon Victory Development Ltd. | Specific biomarker set for non-invasive diagnosis of liver cancer |
| US9885718B2 (en) | 2014-07-02 | 2018-02-06 | Dragon Victory Development Ltd. | Specific biomarker set for non-invasive diagnosis of liver cancer |
| WO2016060382A1 (ko) * | 2014-10-17 | 2016-04-21 | 에스케이텔레콤 주식회사 | 췌장암 진단용 조성물 및 이를 이용한 췌장암 진단방법 |
| KR20160045547A (ko) | 2014-10-17 | 2016-04-27 | 에스케이텔레콤 주식회사 | 췌장암 진단용 조성물 및 이를 이용한 췌장암 진단방법 |
| WO2016094330A2 (en) * | 2014-12-08 | 2016-06-16 | 20/20 Genesystems, Inc | Methods and machine learning systems for predicting the liklihood or risk of having cancer |
| JP2016214239A (ja) * | 2015-05-15 | 2016-12-22 | 国立大学法人高知大学 | 膵がんマーカー |
| US20180216194A1 (en) * | 2015-07-28 | 2018-08-02 | The Johns Hopkins University | Compositions and methods for detecting pancreatic cancer |
| WO2017044715A1 (en) * | 2015-09-09 | 2017-03-16 | Somalogic, Inc. | Methods for developing personalized drug treatment plans and targeted drug development based on proteomic profiles |
| US11051790B2 (en) * | 2015-11-10 | 2021-07-06 | Exact Imaging, Inc. | System comprising indicator features in high-resolution micro-ultrasound images |
| JP6498107B2 (ja) * | 2015-11-30 | 2019-04-10 | 日本電信電話株式会社 | 分類装置、方法、及びプログラム |
| CN116008563B (zh) * | 2016-02-08 | 2025-12-19 | 私募蛋白质体操作有限公司 | 非酒精性脂肪肝疾病(nafld)和非酒精性脂肪性肝炎(nash)生物标记及其用途 |
| GB201608192D0 (en) * | 2016-05-10 | 2016-06-22 | Immunovia Ab | Method, array and use thereof |
| EP3458992B1 (en) * | 2016-05-19 | 2022-03-02 | Quartz Bio SA | Biomarkers signature discovery and selection |
| JP7057913B2 (ja) * | 2016-06-09 | 2022-04-21 | 株式会社島津製作所 | ビッグデータ解析方法及び該解析方法を利用した質量分析システム |
| CN110023950B (zh) * | 2016-10-28 | 2023-08-08 | 拜克门寇尔特公司 | 物质准备评估系统 |
| WO2018156973A1 (en) | 2017-02-24 | 2018-08-30 | Board Of Regents, The University Of Texas System | Assay for detection of early stage pancreatic cancer |
| CN108931650A (zh) * | 2017-05-24 | 2018-12-04 | 宜昌市中心人民医院 | 一种激肽释放酶7在血液中的活性检测方法及其作为诊断胰腺癌的血清标志物上的应用 |
| CN108931651A (zh) * | 2017-05-24 | 2018-12-04 | 宜昌市中心人民医院 | 一种激肽释放酶7在血液中的含量检测方法及其作为诊断胰腺癌的血清标志物上的应用 |
| WO2019010429A1 (en) * | 2017-07-07 | 2019-01-10 | The Trustees Of The University Of Pennsylvania | METHODS OF DIAGNOSING PANCREATIC CANCER |
| US11062792B2 (en) * | 2017-07-18 | 2021-07-13 | Analytics For Life Inc. | Discovering genomes to use in machine learning techniques |
| US11139048B2 (en) | 2017-07-18 | 2021-10-05 | Analytics For Life Inc. | Discovering novel features to use in machine learning techniques, such as machine learning techniques for diagnosing medical conditions |
| CN107389776B (zh) * | 2017-07-18 | 2020-06-02 | 宁波瑞瑧生物科技有限公司 | 一种用于检测药物分布的分析方法及其应用 |
| KR101830314B1 (ko) | 2017-07-26 | 2018-02-20 | 재단법인 구미전자정보기술원 | 인공지능 기반 베이지안 네트워크를 이용한 췌장암 진단에 필요한 정보제공 방법, 컴퓨터 프로그램 및 컴퓨터 판독 가능한 기록 매체 |
| CN109425739B (zh) * | 2017-08-31 | 2022-03-18 | 复旦大学 | 一组蛋白作为肿瘤标志物在制备恶性肿瘤诊断试剂和试剂盒中的用途 |
| AU2019217331B2 (en) * | 2018-01-30 | 2024-11-07 | Sri International | Computational generation of chemical synthesis routes and methods |
| JP7455757B2 (ja) * | 2018-04-13 | 2024-03-26 | フリーノーム・ホールディングス・インコーポレイテッド | 生体試料の多検体アッセイのための機械学習実装 |
| WO2019232361A1 (en) * | 2018-05-31 | 2019-12-05 | University Of Florida Research Foundation | Personalized treatment of pancreatic cancer |
| WO2020041748A1 (en) * | 2018-08-24 | 2020-02-27 | The Regents Of The University Of California | Mhc-ii genotype restricts the oncogenic mutational landscape |
| EP3853383A1 (en) * | 2018-09-19 | 2021-07-28 | Bluestar Genomics, Inc. | Cell-free dna hydroxymethylation profiles in the evaluation of pancreatic lesions |
| CN109919688B (zh) * | 2019-03-29 | 2021-03-05 | 杭州电子科技大学 | 一种考虑市场因素的电子烟产品线规划方法 |
| CN114026253B (zh) * | 2019-04-22 | 2025-08-12 | 奥比特基因组学公司 | 用于微卫星分析的方法和系统 |
| EP3959719A4 (en) * | 2019-04-26 | 2022-06-01 | Sean Kelly | DEVICE FOR PERSONAL PREDICTIVE ENRICHMENT OF A BIOMARKER AND METHODS OF USE THEREOF |
| EP4041888A4 (en) | 2019-10-11 | 2023-11-01 | Guardant Health, Inc. | USE OF CELLULAR BACTERIAL NUCLEIC ACIDS FOR CANCER DETECTION |
| EP4045912A1 (en) * | 2019-10-18 | 2022-08-24 | Reccan Diagnostics AB | Apparatuses and methods for detection of pancreatic cancer |
| CN111584010B (zh) * | 2020-04-01 | 2022-05-27 | 昆明理工大学 | 一种基于胶囊神经网络和集成学习的关键蛋白质识别方法 |
| EP4407042A3 (en) | 2020-07-10 | 2024-09-18 | Guardant Health, Inc. | Methods of detecting genomic rearrangements using cell free nucleic acids |
| WO2023282916A1 (en) | 2021-07-09 | 2023-01-12 | Guardant Health, Inc. | Methods of detecting genomic rearrangements using cell free nucleic acids |
| CA3192386A1 (en) * | 2020-09-10 | 2022-03-17 | Jim ABRAHAM | Metastasis predictor |
| CN114250298B (zh) * | 2020-09-23 | 2024-09-24 | 中国医学科学院北京协和医院 | 胰腺导管腺癌的dna甲基化标志物及其应用 |
| WO2022139465A1 (ko) * | 2020-12-22 | 2022-06-30 | 두에이아이(주) | 인공지능 라만 분석 기법을 이용한 췌장암 조기진단 방법 |
| US20240369559A1 (en) * | 2021-04-21 | 2024-11-07 | Reccan Diagnostics Ab | Pancreatic cancer detection |
| EP4326297A4 (en) * | 2021-04-21 | 2025-06-04 | Rutgers, the State University of New Jersey | Methods for analyzing single-cell host-microbiome interactions and associated gene signatures in cancer |
| CN113096125B (zh) * | 2021-05-11 | 2024-05-31 | 上海宝藤生物医药科技股份有限公司 | 低密度脂蛋白试剂浓度的确定方法、装置及存储介质 |
| WO2023102443A2 (en) * | 2021-11-30 | 2023-06-08 | Venn Biosciences Corporation | Diagnosis of pancreatic cancer using targeted quantification of site-specific protein glycosylation |
| EP4457358A1 (en) * | 2021-12-30 | 2024-11-06 | SomaLogic Operating Co., Inc. | Next-generation sequencing for protein measurement |
| WO2023196571A1 (en) * | 2022-04-08 | 2023-10-12 | The Johns Hopkins University | Machine learning detection of hypermetabolic cancer based on nuclear magnetic resonance spectra |
| JP2025524379A (ja) * | 2022-06-10 | 2025-07-30 | シティ・オブ・ホープ | 膵臓がんにおけるバイオマーカー |
| KR102651556B1 (ko) * | 2022-09-28 | 2024-03-27 | 주식회사 휴벳바이오 | Ca19-9 수준이 낮은 환자의 췌장암 진단용 조성물 |
| WO2024192491A1 (pt) * | 2023-03-23 | 2024-09-26 | Huna Ltda. | Treinamento e aplicação de modelos de inteligência artificial para a previsão de ocorrência de câncer em um indivíduo |
| AU2024257583A1 (en) * | 2023-04-19 | 2025-11-20 | Molecular You Corporation | Method of diagnosis and treatment of pancreatic cancer |
| KR20250169643A (ko) * | 2024-05-22 | 2025-12-04 | 주식회사 베르티스 | 췌장암의 진단용 신규 바이오마커 |
Family Cites Families (123)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5660985A (en) | 1990-06-11 | 1997-08-26 | Nexstar Pharmaceuticals, Inc. | High affinity nucleic acid ligands containing modified nucleotides |
| US20040254101A1 (en) * | 1995-06-06 | 2004-12-16 | Human Genome Sciences, Inc. | Colon specific gene and protein and cancer |
| US6004267A (en) | 1997-03-07 | 1999-12-21 | University Of Florida | Method for diagnosing and staging prostate cancer |
| US6335170B1 (en) | 1999-02-22 | 2002-01-01 | Torben F. Orntoft | Gene expression in bladder tumors |
| ATE400813T1 (de) | 1999-09-10 | 2008-07-15 | Takashi Muramatsu | Tumormarker für frühes krebsstadium |
| US20030144476A1 (en) | 2000-03-06 | 2003-07-31 | Pankaj Agarwal | Novel compounds |
| US6596503B1 (en) | 2000-08-18 | 2003-07-22 | East Carolina University | Monoclonal antibody DS6, tumor-associated antigen CA6, and methods of use thereof |
| US6631330B1 (en) | 2000-08-21 | 2003-10-07 | Assistance Publique-Hopitaux De Paris (Ap-Hp) | Diagnosis method of inflammatory, fibrotic or cancerous disease using biochemical markers |
| US6576423B2 (en) * | 2000-12-08 | 2003-06-10 | The Board Of Regents Of The University Of Nebraska | Specific mucin expression as a marker for pancreatic cancer |
| NZ528205A (en) | 2001-03-12 | 2006-09-29 | Monogen Inc | Cell-based detection and differentiation of disease status in a cytological sample using a panel comprising a plurality of probes |
| CA2444691A1 (en) | 2001-04-18 | 2002-10-31 | Protein Design Labs, Inc. | Methods of diagnosis of lung cancer, compositions and methods of screening for modulators of lung cancer |
| US7189507B2 (en) | 2001-06-18 | 2007-03-13 | Pdl Biopharma, Inc. | Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer |
| US7622260B2 (en) | 2001-09-05 | 2009-11-24 | The Brigham And Women's Hospital, Inc. | Diagnostic and prognostic tests |
| US20040009489A1 (en) | 2001-09-28 | 2004-01-15 | Golub Todd R. | Classification of lung carcinomas using gene expression analysis |
| WO2003058201A2 (en) | 2001-12-31 | 2003-07-17 | Quark Biotech, Inc. | Methods for identifying marker genes for cancer |
| CA2992643C (en) | 2002-03-13 | 2019-06-18 | Genomic Health, Inc. | Gene expression profiling in biopsied tumor tissues |
| US20050260639A1 (en) * | 2002-09-30 | 2005-11-24 | Oncotherapy Science, Inc. | Method for diagnosing pancreatic cancer |
| ES2320443T3 (es) * | 2002-09-30 | 2009-05-22 | Oncotherapy Science, Inc. | Genes y polipeptidos relacionados con canceres pancreaticos humanos. |
| AU2003295598B2 (en) | 2002-11-15 | 2009-12-24 | Genomic Health, Inc. | Gene expression profiling of EGFR positive cancer |
| AU2003294828A1 (en) * | 2002-12-17 | 2004-07-09 | Sinogenomax Co. Ltd. Chinese National Human Genomecenter | Specific markers for pancreatic cancer |
| CN1726395A (zh) * | 2002-12-17 | 2006-01-25 | 北京诺赛基因组研究中心有限公司 | 胰腺癌的特异标记 |
| US8014952B2 (en) | 2002-12-18 | 2011-09-06 | Queen Elizabeth Hospital | Serum biomarkers in lung cancer |
| WO2004063355A2 (en) | 2003-01-10 | 2004-07-29 | Protein Design Labs, Inc. | Novel methods of diagnosis of metastatic cancer, compositions and methods of screening for modulators of matastatic cancer |
| US20040231909A1 (en) | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| AU2003900747A0 (en) | 2003-02-18 | 2003-03-06 | Garvan Institute Of Medical Research | Diagnosis and treatment of pancreatic cancer |
| CA2516553C (en) | 2003-02-20 | 2013-04-16 | Genomic Health, Inc. | Use of intronic rna to measure gene expression |
| CA2516591A1 (en) | 2003-02-26 | 2004-09-10 | Mount Sinai Hospital | Multiple marker assay for detection of ovarian cancer |
| US20050095611A1 (en) * | 2003-05-02 | 2005-05-05 | Chan Daniel W. | Identification of biomarkers for detecting pancreatic cancer |
| CN1852974A (zh) * | 2003-06-09 | 2006-10-25 | 密歇根大学董事会 | 用于治疗和诊断癌症的组合物和方法 |
| EP1639090A4 (en) | 2003-06-09 | 2008-04-16 | Univ Michigan | COMPOSITIONS AND METHODS OF TREATMENT AND DIAGNOSIS OF CANCER |
| ES2609234T3 (es) | 2003-06-24 | 2017-04-19 | Genomic Health, Inc. | Predicción de la probabilidad de recidiva de cáncer |
| US7526387B2 (en) | 2003-07-10 | 2009-04-28 | Genomic Health, Inc. | Expression profile algorithm and test for cancer prognosis |
| AU2004264948A1 (en) | 2003-08-15 | 2005-02-24 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Multifactorial assay for cancer detection |
| US7807392B1 (en) | 2003-09-15 | 2010-10-05 | Celera Corporation | Lung disease targets and uses thereof |
| EP1682904A2 (en) | 2003-11-04 | 2006-07-26 | Roche Diagnostics GmbH | Method for distinguishing who classified aml subtypes |
| US20050181451A1 (en) | 2004-02-12 | 2005-08-18 | Bates Harold M. | Detection of asymptomatic coronary artery disease using atherogenic proteins and acute phase reactants |
| US7666583B2 (en) | 2004-02-19 | 2010-02-23 | Yale University | Identification of cancer protein biomarkers using proteomic techniques |
| US8019552B2 (en) | 2004-03-05 | 2011-09-13 | The Netherlands Cancer Institute | Classification of breast cancer patients using a combination of clinical criteria and informative genesets |
| CA2563074C (en) | 2004-04-09 | 2014-05-20 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
| CA2578680C (en) | 2004-04-15 | 2011-06-14 | University Of Florida Research Foundation, Inc. | Proteolytic markers as diagnostic biomarkers for cancer, organ injury and muscle rehabilitation/exercise overtraining |
| AU2005236075A1 (en) | 2004-04-26 | 2005-11-03 | Children's Medical Center Corporation | Platelet biomarkers for the detection of disease |
| WO2006022643A1 (en) | 2004-07-26 | 2006-03-02 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for detecting pancreatic disease |
| MX2007001357A (es) | 2004-08-02 | 2009-08-07 | Childrens Medical Center | Biomarcadores de plaquetas para cancer. |
| JP2006053113A (ja) | 2004-08-16 | 2006-02-23 | Medical Proteoscope Co Ltd | 肺腺癌リンパ節転移診断方法及び診断キット |
| JP5020088B2 (ja) | 2004-11-05 | 2012-09-05 | ジェノミック ヘルス， インコーポレイテッド | 遺伝子発現マーカーを使用する、化学療法に対する反応の予測 |
| EP1815014B1 (en) | 2004-11-05 | 2012-03-21 | Genomic Health, Inc. | Molecular indicators of breast cancer prognosis and prediction of treatment response |
| US7862995B2 (en) | 2004-12-10 | 2011-01-04 | Targeted Molecular Diagnostics | Methods and materials for predicting responsiveness to treatment with dual tyrosine kinase inhibitor |
| US8632983B2 (en) | 2005-04-15 | 2014-01-21 | Van Andel Research Institute | Biomarkers for pancreatic cancer and diagnostic methods |
| WO2006135886A2 (en) | 2005-06-13 | 2006-12-21 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| EP1904649A2 (en) | 2005-07-18 | 2008-04-02 | Epigenomics AG | Compositions and methods for cancer diagnostics comprising pan-cancer markers |
| US7521195B1 (en) | 2005-07-21 | 2009-04-21 | Celera Corporation | Lung disease targets and uses thereof |
| CN101283106A (zh) | 2005-07-27 | 2008-10-08 | 肿瘤疗法科学股份有限公司 | 小细胞肺癌的诊断方法 |
| EP1937837A2 (en) | 2005-07-29 | 2008-07-02 | Siemens Healthcare Diagnostics Inc. | Methods and kits for the prediction of therapeutic success, recurrence free and overall survival in cancer therapies |
| US7582441B1 (en) | 2005-10-17 | 2009-09-01 | Celera Corporation | Methods and compositions for treating and diagnosing disease |
| EP1777523A1 (en) | 2005-10-19 | 2007-04-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | An in vitro method for the prognosis of progression of a cancer and of the outcome in a patient and means for performing said method |
| US8329408B2 (en) | 2005-10-31 | 2012-12-11 | Bayer Healthcare Llc | Methods for prognosis and monitoring cancer therapy |
| CN103245784A (zh) | 2005-11-10 | 2013-08-14 | 肯塔基大学研究基金会 | 肺癌的诊断分析法 |
| US8445198B2 (en) | 2005-12-01 | 2013-05-21 | Medical Prognosis Institute | Methods, kits and devices for identifying biomarkers of treatment response and use thereof to predict treatment efficacy |
| US8014957B2 (en) | 2005-12-15 | 2011-09-06 | Fred Hutchinson Cancer Research Center | Genes associated with progression and response in chronic myeloid leukemia and uses thereof |
| EP1969363B1 (en) | 2005-12-22 | 2016-11-30 | Abbott Molecular Inc. | Methods and marker combinations for screening for predisposition to lung cancer |
| NZ593226A (en) | 2006-01-11 | 2012-10-26 | Genomic Health Inc | Gene expression markers (efnb2) for colorectal cancer prognosis |
| EP2363711A1 (en) | 2006-01-27 | 2011-09-07 | Tripath Imaging, Inc. | Methods for identifying patients with an increased likelihood of having ovarian cancer and compositions therefor |
| EP1986655A4 (en) * | 2006-02-06 | 2009-12-23 | Tethys Bioscience Inc | MARKERS ASSOCIATED WITH OSTEOPOROSIS AND METHODS OF USE |
| EP1991872A1 (en) * | 2006-03-02 | 2008-11-19 | Oncotherapy Science, Inc. | Methods for diagnosing pancreatic cancer using reg4 protein |
| US7908091B2 (en) | 2006-03-17 | 2011-03-15 | Prometheus Laboratories Inc. | Methods of predicting and monitoring tyrosine kinase inhibitor therapy |
| WO2007123772A2 (en) | 2006-03-31 | 2007-11-01 | Genomic Health, Inc. | Genes involved in estrogen metabolism |
| CA2648385C (en) | 2006-04-04 | 2020-09-01 | Singulex, Inc. | Highly sensitive system and methods for analysis of troponin |
| EP2302395B1 (en) | 2006-06-07 | 2015-04-15 | Health Diagnostic Laboratory, Inc. | Markers associated with arteriovascular events and methods of use thereof |
| WO2008003024A2 (en) | 2006-06-28 | 2008-01-03 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Method and composition for diagnosing endometrial cancer |
| WO2008046911A2 (en) | 2006-10-20 | 2008-04-24 | Exiqon A/S | Novel human micrornas associated with cancer |
| WO2008063413A2 (en) | 2006-11-13 | 2008-05-29 | Source Precision Medicine, Inc. | Gene expression profiling for identification, monitoring, and treatment of lung cancer |
| WO2008086182A2 (en) | 2007-01-04 | 2008-07-17 | University Of Rochester | Use of gene signatures to design novel cancer treatment regimens |
| US7947447B2 (en) | 2007-01-16 | 2011-05-24 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
| KR100846354B1 (ko) | 2007-03-21 | 2008-07-15 | (주) 프로탄바이오 | 혈청 당단백질부터 분리한 폐암 진단용 마커 |
| CA2681899C (en) * | 2007-03-27 | 2018-06-19 | Immunovia Ab | Methods for diagnosis of pancreatic adenocarcinoma, and biomarkers and arrays for use in the same |
| US20080274481A1 (en) | 2007-03-28 | 2008-11-06 | Vermillion, Inc. | Methods for diagnosing ovarian cancer |
| CA2681667A1 (en) | 2007-05-18 | 2008-11-27 | Duke University | Serum biomarkers for the early detection of lung cancer |
| US20100183514A1 (en) * | 2007-05-29 | 2010-07-22 | President And Fellows Of Harvard College | Molecules involved in regulation of osteoblast activity and osteoclast activity, and methods of use thereof |
| GB0717637D0 (en) | 2007-09-10 | 2007-10-17 | Univ Leiden | Future cardiac event biomarkers |
| US8541183B2 (en) | 2007-09-11 | 2013-09-24 | Cancer Prevention And Cure, Ltd. | Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof |
| US7888051B2 (en) | 2007-09-11 | 2011-02-15 | Cancer Prevention And Cure, Ltd. | Method of identifying biomarkers in human serum indicative of pathologies of human lung tissues |
| US20100267041A1 (en) * | 2007-09-14 | 2010-10-21 | Predictive Biosciences, Inc. | Serial analysis of biomarkers for disease diagnosis |
| CA2700125A1 (en) | 2007-09-18 | 2009-03-26 | Board Of Regents Of The University Of Texas System | Detection of saliva proteins modulated secondary to ductal carcinoma in situ of the breast |
| US7892760B2 (en) | 2007-11-19 | 2011-02-22 | Celera Corporation | Lung cancer markers, and uses thereof |
| US20090186370A1 (en) | 2008-01-18 | 2009-07-23 | Ogle Matthew F | Diagnostic biomarkers for vascular aneurysm |
| GB0803192D0 (en) | 2008-02-22 | 2008-04-02 | Mubio Products Bv | SCLC biomarker panel |
| WO2009114836A1 (en) | 2008-03-14 | 2009-09-17 | Genomic Health, Inc. | Gene expression markers for prediction of patient response to chemotherapy |
| RU2011103915A (ru) * | 2008-07-04 | 2012-08-10 | Кабусики Кайся Тосиба (Jp) | Способ и устройство кодирования/декодирования движущегося изображения |
| US10359425B2 (en) | 2008-09-09 | 2019-07-23 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| WO2012006632A2 (en) | 2010-07-09 | 2012-01-12 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| CA3152591C (en) | 2008-09-09 | 2023-08-29 | Somalogic Operating Co., Inc. | Lung cancer biomarkers and uses thereof |
| US20120143805A1 (en) | 2008-09-09 | 2012-06-07 | Somalogic, Inc. | Cancer Biomarkers and Uses Thereof |
| NZ592241A (en) * | 2008-09-15 | 2012-11-30 | Herlev Hospital | Ykl-40 as a marker for gastrointestinal cancers |
| US20100221752A2 (en) | 2008-10-06 | 2010-09-02 | Somalogic, Inc. | Ovarian Cancer Biomarkers and Uses Thereof |
| CA2737004A1 (en) | 2008-10-06 | 2010-04-15 | Somalogic, Inc. | Ovarian cancer biomarkers and uses thereof |
| US20120165217A1 (en) | 2008-10-06 | 2012-06-28 | Somalogic, Inc. | Cancer Biomarkers and Uses Thereof |
| CA2741117A1 (en) | 2008-10-30 | 2010-05-06 | Centre De Recherche Public De La Sante | Biomarkers for heart failure |
| WO2011109440A1 (en) | 2010-03-01 | 2011-09-09 | Caris Life Sciences Luxembourg Holdings | Biomarkers for theranostics |
| WO2010056374A2 (en) | 2008-11-17 | 2010-05-20 | Veracyte, Inc. | Methods and compositions of molecular profiling for disease diagnostics |
| WO2010059742A1 (en) | 2008-11-18 | 2010-05-27 | Collabrx, Inc. | Individualized cancer treatment |
| CA2745961A1 (en) | 2008-12-04 | 2010-06-10 | The Regents Of The University Of California | Materials and methods for determining diagnosis and prognosis of prostate cancer |
| JP5678045B2 (ja) | 2009-06-08 | 2015-02-25 | シンギュレックス・インコーポレイテッド | 高感度バイオマーカーパネル |
| ES2623633T3 (es) | 2009-06-09 | 2017-07-11 | Gendiag.Exe, S.L. | Marcadores de riesgo para enfermedad cardiovascular |
| JP2012529914A (ja) | 2009-06-15 | 2012-11-29 | カーディオ ディーエクス インコーポレイティッド | 冠動脈疾患リスクの判定法 |
| WO2011022552A2 (en) | 2009-08-19 | 2011-02-24 | The Cleveland Clinic Foundation | Marker Detection for Characterizing the Risk of Cardiovascular Disease or Complications Thereof |
| US20120178111A1 (en) | 2009-09-23 | 2012-07-12 | Diamandis Eleftherios P | Methods and compositions for the detection of lung cancers |
| SG10201405975VA (en) * | 2009-10-01 | 2014-11-27 | Phenomenome Discoveries Inc | Serum-based biomarkers of pancreatic cancer and uses thereof for diseasedetection and diagnosis |
| US9683996B2 (en) | 2009-10-22 | 2017-06-20 | The Regents Of The University Of California | Assessment of solid tumor burden |
| US9217747B2 (en) | 2009-10-29 | 2015-12-22 | Health Diagnostic Laboratory, Inc. | Protein and lipid biomarkers providing consistent improvement to the prediction of type 2 diabetes |
| US20120245235A1 (en) * | 2009-12-01 | 2012-09-27 | Compenda Bioscience, Inc | Classification of cancers |
| CN102762743A (zh) | 2009-12-09 | 2012-10-31 | 阿维埃尔公司 | 用于心血管疾病的诊断和分类的生物标记物检验 |
| EP3178944B1 (en) | 2010-01-11 | 2019-05-15 | Genomic Health, Inc. | Method to use gene expression to determine likelihood of clinical outcome of renal cancer |
| WO2011094483A2 (en) | 2010-01-29 | 2011-08-04 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Immune gene signatures in cancer |
| CA2789494C (en) | 2010-02-10 | 2021-08-17 | The Regents Of The University Of California | Salivary biomarkers for lung cancer detection |
| US9624547B2 (en) | 2010-02-10 | 2017-04-18 | The Regents Of The University Of California | Salivary transcriptomic and proteomic biomarkers for breast cancer detection |
| WO2011127219A1 (en) | 2010-04-06 | 2011-10-13 | Caris Life Sciences Luxembourg Holdings | Circulating biomarkers for disease |
| SG187045A1 (en) | 2010-08-13 | 2013-02-28 | Somalogic Inc | Pancreatic cancer biomarkers and uses thereof |
| CN103429753A (zh) | 2010-09-27 | 2013-12-04 | 私募蛋白质体公司 | 间皮瘤生物标记及其用途 |
| EP3825693A1 (en) | 2011-04-29 | 2021-05-26 | Cancer Prevention And Cure, Ltd. | Methods of identification and diagnosis of lung diseases using classification systems and kits thereof |
| EP2748356A2 (en) | 2011-08-22 | 2014-07-02 | Somalogic, Inc. | Renal cell carcinoma biomarkers and uses thereof |
| MX373248B (es) | 2011-09-30 | 2020-05-11 | Somalogic Operating Co Inc | Prediccion de riesgo de evento cardiovascular y usos del mismo. |
| WO2013142114A1 (en) | 2012-03-19 | 2013-09-26 | The Brigham And Women's Hosptial, Inc. | Growth differentiation factor (gdf) for treatment of diastolic heart failure |
| BR112016010165A2 (pt) | 2013-11-21 | 2017-12-05 | Somalogic Inc | composições de nucleotídeos modificados de citidina-5-carboxamida e métodos relacionados às mesmas |
-
2011
- 2011-08-12 SG SG2013002456A patent/SG187045A1/en unknown
- 2011-08-12 US US13/208,903 patent/US20120040861A1/en not_active Abandoned
- 2011-08-12 MX MX2016010635A patent/MX350533B/es unknown
- 2011-08-12 SG SG2014007454A patent/SG2014007454A/en unknown
- 2011-08-12 CA CA2804857A patent/CA2804857C/en active Active
- 2011-08-12 BR BR112013003391A patent/BR112013003391B8/pt not_active IP Right Cessation
- 2011-08-12 EP EP11817097.6A patent/EP2603622A4/en not_active Withdrawn
- 2011-08-12 KR KR1020137003215A patent/KR101857462B1/ko not_active Expired - Fee Related
- 2011-08-12 AU AU2011289284A patent/AU2011289284B2/en not_active Ceased
- 2011-08-12 CN CN201180049408.2A patent/CN103415624B/zh not_active Expired - Fee Related
- 2011-08-12 MX MX2013001042A patent/MX341517B/es active IP Right Grant
- 2011-08-12 WO PCT/US2011/047570 patent/WO2012021795A2/en not_active Ceased
- 2011-08-12 SG SG10201710447QA patent/SG10201710447QA/en unknown
- 2011-08-12 CN CN201610479435.8A patent/CN106198980B/zh not_active Expired - Fee Related
- 2011-08-12 JP JP2013525961A patent/JP5931874B2/ja not_active Expired - Fee Related
-
2012
- 2012-12-30 IL IL224014A patent/IL224014A/en active IP Right Grant
-
2013
- 2013-09-06 US US14/020,334 patent/US20140073522A1/en not_active Abandoned
-
2015
- 2015-05-28 AU AU2015202907A patent/AU2015202907B2/en not_active Ceased
-
2016
- 2016-12-06 AU AU2016269430A patent/AU2016269430B2/en not_active Ceased
-
2017
- 2017-08-17 US US15/679,643 patent/US11041866B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2013541697A5 (https=) | ||
| He et al. | Sepsis biomarkers: advancements and clinical applications—a narrative review | |
| Liberto et al. | Current and emerging methods for ovarian cancer screening and diagnostics: a comprehensive review | |
| JP2013532295A5 (https=) | ||
| Lobo et al. | Identification and validation model for informative liquid biopsy-based microRNA biomarkers: insights from germ cell tumor in vitro, in vivo and patient-derived data | |
| Martini et al. | Circulating tumor cells in pancreatic cancer: current perspectives | |
| Zhang et al. | Machine-learning algorithm-based prediction of diagnostic gene biomarkers related to immune infiltration in patients with chronic obstructive pulmonary disease | |
| Muse et al. | A whole blood molecular signature for acute myocardial infarction | |
| Fisic et al. | The Role of IL‐6, 8, and 10, sTNFr, CRP, and pancreatic elastase in the prediction of systemic complications in patients with acute pancreatitis | |
| Matuszczak et al. | A liquid biopsy in bladder cancer—the current landscape in urinary biomarkers | |
| Gualtero et al. | Biomarkers in saliva for the detection of oral squamous cell carcinoma and their potential use for early diagnosis: a systematic review | |
| Singh et al. | Non-invasive biomarkers for celiac disease | |
| Yee et al. | Extracellular vesicles as potential biomarkers for early detection and diagnosis of pancreatic cancer | |
| JP6018923B2 (ja) | 敗血症の予後の予測方法 | |
| ES2868077T3 (es) | Diagnóstico mediante células tumorales circulantes para biomarcadores predictivos de la resistencia a las terapias selectivas del receptor de andrógenos (RA) | |
| KR20200055804A (ko) | 심혈관 위험 사건 예측 및 그것의 용도 | |
| Berezin et al. | Pattern of circulating microparticles in chronic heart failure patients with metabolic syndrome: Relevance to neurohumoral and inflammatory activation | |
| JP2017530356A5 (https=) | ||
| Yasar et al. | Significance of S100A8, S100A9 and calprotectin levels in bladder cancer | |
| Lin et al. | Plasma protein biosignatures for detection of cardiac allograft vasculopathy | |
| Yadav et al. | Emerging role of exosomes as a liquid biopsy tool for diagnosis, prognosis & monitoring treatment response of communicable & non-communicable diseases | |
| Jung et al. | Surface proteome of plasma extracellular vesicles as biomarkers for pneumonia and acute exacerbation of chronic obstructive pulmonary disease | |
| Lee et al. | Machine-learning-based clinical biomarker using cell-free DNA for hepatocellular carcinoma (HCC) | |
| Zhou et al. | Detection of autoantibodies to a panel of tumor-associated antigens for the diagnosis values of gastric cardia adenocarcinoma | |
| Giraudi et al. | Ficolin-2 plasma level assesses liver fibrosis in non-alcoholic fatty liver disease |