SG10201710447QA - Pancreatic cancer biomarkers and uses thereof - Google Patents

Pancreatic cancer biomarkers and uses thereof

Info

Publication number
SG10201710447QA
SG10201710447QA SG10201710447QA SG10201710447QA SG10201710447QA SG 10201710447Q A SG10201710447Q A SG 10201710447QA SG 10201710447Q A SG10201710447Q A SG 10201710447QA SG 10201710447Q A SG10201710447Q A SG 10201710447QA SG 10201710447Q A SG10201710447Q A SG 10201710447QA
Authority
SG
Singapore
Prior art keywords
pancreatic cancer
cancer biomarkers
biomarkers
pancreatic
cancer
Prior art date
Application number
SG10201710447QA
Inventor
Stephen Alaric Williams
Mehan Michael Riel
Rachel M Ostroff
Original Assignee
Somalogic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Somalogic Inc filed Critical Somalogic Inc
Publication of SG10201710447QA publication Critical patent/SG10201710447QA/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00Methods of screening libraries
    • C40B30/04Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57438Specifically defined cancers of liver, pancreas or kidney
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/70Mechanisms involved in disease identification
    • G01N2800/7023(Hyper)proliferation
    • G01N2800/7028Cancer
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
SG10201710447QA 2010-08-13 2011-08-12 Pancreatic cancer biomarkers and uses thereof SG10201710447QA (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US37368710P 2010-08-13 2010-08-13
US41868910P 2010-12-01 2010-12-01
US201161482480P 2011-05-04 2011-05-04
US201161482347P 2011-05-04 2011-05-04

Publications (1)

Publication Number Publication Date
SG10201710447QA true SG10201710447QA (en) 2018-02-27

Family

ID=45565264

Family Applications (3)

Application Number Title Priority Date Filing Date
SG10201710447QA SG10201710447QA (en) 2010-08-13 2011-08-12 Pancreatic cancer biomarkers and uses thereof
SG2014007454A SG2014007454A (en) 2010-08-13 2011-08-12 Pancreatic cancer biomarkers and uses thereof
SG2013002456A SG187045A1 (en) 2010-08-13 2011-08-12 Pancreatic cancer biomarkers and uses thereof

Family Applications After (2)

Application Number Title Priority Date Filing Date
SG2014007454A SG2014007454A (en) 2010-08-13 2011-08-12 Pancreatic cancer biomarkers and uses thereof
SG2013002456A SG187045A1 (en) 2010-08-13 2011-08-12 Pancreatic cancer biomarkers and uses thereof

Country Status (12)

Country Link
US (3) US20120040861A1 (en)
EP (1) EP2603622A4 (en)
JP (1) JP5931874B2 (en)
KR (1) KR101857462B1 (en)
CN (2) CN103415624B (en)
AU (3) AU2011289284B2 (en)
BR (1) BR112013003391B8 (en)
CA (1) CA2804857C (en)
IL (1) IL224014A (en)
MX (2) MX350533B (en)
SG (3) SG10201710447QA (en)
WO (1) WO2012021795A2 (en)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10359425B2 (en) * 2008-09-09 2019-07-23 Somalogic, Inc. Lung cancer biomarkers and uses thereof
CN104777313B (en) 2010-07-09 2017-09-26 私募蛋白质体公司 Lung cancer biomarkers and application thereof
WO2012021795A2 (en) 2010-08-13 2012-02-16 Somalogic, Inc. Pancreatic cancer biomarkers and uses thereof
NL2009015C2 (en) * 2012-04-10 2013-10-15 Biosparq B V Method for classification of a sample on the basis of spectral data, method for creating a database and method for using this database, and corresponding computer program, data storage medium and system.
CA2902841A1 (en) * 2013-03-13 2014-10-02 Creatics Llc Methods and compositions for detecting pancreatic cancer
US20140272969A1 (en) * 2013-03-14 2014-09-18 Abbott Molecular Inc. Cell preparations and cell supports and their use in theranosis
CN103324846A (en) * 2013-06-13 2013-09-25 浙江加州国际纳米技术研究院绍兴分院 Screening method of colorectal cancer treatment prognosis biomarkers
CN103310105A (en) * 2013-06-13 2013-09-18 浙江加州国际纳米技术研究院绍兴分院 Method for screening non-small-cell lung cancer curative effect biomarker
CA2952390A1 (en) * 2013-06-20 2014-12-24 The Trustees Of The University Of Pennsylvania Methods for diagnosing pancreatic cancer
KR101594981B1 (en) * 2013-10-31 2016-02-17 에스케이텔레콤 주식회사 Composition for diagnosing pancreatic cancer and method for diagnosing pancreatic cancer using the same
KR101594980B1 (en) * 2013-10-31 2016-02-17 에스케이텔레콤 주식회사 Composition for diagnosing pancreatic cancer and method for diagnosing pancreatic cancer using the same
US10330682B2 (en) 2013-10-31 2019-06-25 Sk Telecom Co., Ltd. Composition for diagnosing pancreatic cancer and method for diagnosing pancreatic cancer using same
KR20150129932A (en) * 2014-05-12 2015-11-23 연세대학교 산학협력단 A kit for pancreatic cancer diagnosis comprising complememt factor b-specific binding antibody
US9506925B2 (en) 2014-07-02 2016-11-29 Dragon Victory Development Ltd. Specific biomarker set for non-invasive diagnosis of liver cancer
US9885718B2 (en) 2014-07-02 2018-02-06 Dragon Victory Development Ltd. Specific biomarker set for non-invasive diagnosis of liver cancer
WO2016060382A1 (en) * 2014-10-17 2016-04-21 에스케이텔레콤 주식회사 Composition for diagnosing pancreatic cancer and method for diagnosing pancreatic cancer by using same
KR20160045547A (en) 2014-10-17 2016-04-27 에스케이텔레콤 주식회사 Composition for diagnosing pancreatic cancer and method for diagnosing pancreatic cancer using the same
WO2016094330A2 (en) * 2014-12-08 2016-06-16 20/20 Genesystems, Inc Methods and machine learning systems for predicting the liklihood or risk of having cancer
JP2016214239A (en) * 2015-05-15 2016-12-22 国立大学法人高知大学 Pancreatic cancer marker
WO2017019588A1 (en) * 2015-07-28 2017-02-02 The Johns Hopkins University Compositions and methods for detecting pancreatic cancer
EP3347720A1 (en) * 2015-09-09 2018-07-18 Somalogic, Inc. Methods for developing personalized drug treatment plans and targeted drug development based on proteomic profiles
EP3373820A4 (en) * 2015-11-10 2019-06-26 Exact Imaging Inc. A system comprising indicator features in high-resolution micro-ultrasound images
JP6498107B2 (en) * 2015-11-30 2019-04-10 日本電信電話株式会社 Classification apparatus, method, and program
WO2017139254A1 (en) * 2016-02-08 2017-08-17 Somalogic, Inc. Nonalcoholic fatty liver disease (nafld) and nonalcoholic steatohepatitis (nash) biomarkers and uses thereof
GB201608192D0 (en) * 2016-05-10 2016-06-22 Immunovia Ab Method, array and use thereof
EP3458992B1 (en) * 2016-05-19 2022-03-02 Quartz Bio SA Biomarkers signature discovery and selection
JP7057913B2 (en) * 2016-06-09 2022-04-21 株式会社島津製作所 Big data analysis method and mass spectrometry system using the analysis method
CN117058415A (en) * 2016-10-28 2023-11-14 贝克曼库尔特有限公司 Substance preparation evaluation system
US11693007B2 (en) 2017-02-24 2023-07-04 Board Of Regents, The University Of Texas System Assay for detection of early stage pancreatic cancer
CN108931651A (en) * 2017-05-24 2018-12-04 宜昌市中心人民医院 A kind of kallikrein 7 detection method of content in blood and its as the application on the blood serum designated object of diagnosis of pancreatic cancer
CN108931650A (en) * 2017-05-24 2018-12-04 宜昌市中心人民医院 A kind of kallikrein 7 activity test method in blood and its as the application on the blood serum designated object of diagnosis of pancreatic cancer
US20200249235A1 (en) * 2017-07-07 2020-08-06 The Trustees Of The University Of Pennsylvania Methods for diagnosing pancreatic cancer
CN107389776B (en) * 2017-07-18 2020-06-02 宁波瑞瑧生物科技有限公司 Analysis method for detecting drug distribution and application thereof
US11062792B2 (en) * 2017-07-18 2021-07-13 Analytics For Life Inc. Discovering genomes to use in machine learning techniques
US11139048B2 (en) 2017-07-18 2021-10-05 Analytics For Life Inc. Discovering novel features to use in machine learning techniques, such as machine learning techniques for diagnosing medical conditions
KR101830314B1 (en) 2017-07-26 2018-02-20 재단법인 구미전자정보기술원 A method of providing information for the diagnosis of pancreatic cancer using bayesian network based on artificial intelligence, computer program, and computer-readable recording media using the same
CN109425739B (en) * 2017-08-31 2022-03-18 复旦大学 Application of a group of proteins as tumor markers in preparation of malignant tumor diagnosis reagent and kit
CA3095056A1 (en) * 2018-04-13 2019-10-17 Freenome Holdings, Inc. Machine learning implementation for multi-analyte assay of biological samples
WO2019232361A1 (en) * 2018-05-31 2019-12-05 University Of Florida Research Foundation Personalized treatment of pancreatic cancer
US20210181188A1 (en) * 2018-08-24 2021-06-17 The Regents Of The University Of California Mhc-ii genotype restricts the oncogenic mutational landscape
US20200123616A1 (en) * 2018-09-19 2020-04-23 Bluestar Genomics, Inc. Cell-free dna hydroxymethylation profiles in the evaluation of pancreatic lesions
CN109919688B (en) * 2019-03-29 2021-03-05 杭州电子科技大学 Electronic cigarette product line planning method considering market factors
CA3137738A1 (en) * 2019-04-26 2020-10-29 Sean Kelly Device for personal predictive enrichment of a biomarker and methods of use thereof
CN111584010B (en) * 2020-04-01 2022-05-27 昆明理工大学 Key protein identification method based on capsule neural network and ensemble learning
WO2023282916A1 (en) 2021-07-09 2023-01-12 Guardant Health, Inc. Methods of detecting genomic rearrangements using cell free nucleic acids
IL301304A (en) * 2020-09-10 2023-05-01 Caris Mpi Inc Metastasis predictor
CN114250298A (en) * 2020-09-23 2022-03-29 中国医学科学院北京协和医院 DNA methylation marker of pancreatic ductal adenocarcinoma and application thereof
KR20220091408A (en) * 2020-12-22 2022-06-30 두에이아이(주) Method for early diagnosis of pancreatic cancerusing artificial intelligence raman analysis technique
EP4327098A1 (en) * 2021-04-21 2024-02-28 Reccan Diagnostics AB Pancreatic cancer detection
CN113096125A (en) * 2021-05-11 2021-07-09 上海宝藤生物医药科技股份有限公司 Method and device for determining concentration of low-density lipoprotein reagent and storage medium
WO2023196571A1 (en) * 2022-04-08 2023-10-12 The Johns Hopkins University Machine learning detection of hypermetabolic cancer based on nuclear magnetic resonance spectra
WO2023239920A1 (en) * 2022-06-10 2023-12-14 City Of Hope Biomarkers in pancreatic cancer
KR102651556B1 (en) * 2022-09-28 2024-03-27 주식회사 휴벳바이오 Composition for Diagnosing Pancreatic Cancer for Use in CA19-9 Low Patient

Family Cites Families (123)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5660985A (en) 1990-06-11 1997-08-26 Nexstar Pharmaceuticals, Inc. High affinity nucleic acid ligands containing modified nucleotides
US20040254101A1 (en) * 1995-06-06 2004-12-16 Human Genome Sciences, Inc. Colon specific gene and protein and cancer
AU6688598A (en) 1997-03-07 1998-09-22 University Of Florida Method for diagnosing and staging prostate cancer
AU3316600A (en) 1999-02-22 2000-09-21 Torben F. Orntoft Gene expression in bladder tumors
US7090983B1 (en) 1999-09-10 2006-08-15 Takashi Muramatsu Methods for detecting early cancer
EP1472352A4 (en) 2000-03-06 2005-10-12 Smithkline Beecham Corp Novel compounds
US6596503B1 (en) 2000-08-18 2003-07-22 East Carolina University Monoclonal antibody DS6, tumor-associated antigen CA6, and methods of use thereof
US6631330B1 (en) 2000-08-21 2003-10-07 Assistance Publique-Hopitaux De Paris (Ap-Hp) Diagnosis method of inflammatory, fibrotic or cancerous disease using biochemical markers
US6576423B2 (en) * 2000-12-08 2003-06-10 The Board Of Regents Of The University Of Nebraska Specific mucin expression as a marker for pancreatic cancer
EP1373896A2 (en) 2001-03-12 2004-01-02 MonoGen, Inc. Cell-based detection and differentiation of disease states
CA2444691A1 (en) 2001-04-18 2002-10-31 Protein Design Labs, Inc. Methods of diagnosis of lung cancer, compositions and methods of screening for modulators of lung cancer
US7189507B2 (en) 2001-06-18 2007-03-13 Pdl Biopharma, Inc. Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
US7622260B2 (en) 2001-09-05 2009-11-24 The Brigham And Women's Hospital, Inc. Diagnostic and prognostic tests
WO2003029273A2 (en) 2001-09-28 2003-04-10 Whitehead Institute For Biomedical Research Classification of lung carcinomas using gene expression analysis
US20040241653A1 (en) 2001-12-31 2004-12-02 Elena Feinstein Methods for identifying marker genes for cancer
DK1918386T3 (en) 2002-03-13 2012-01-02 Genomic Health Inc Gene expression profiles in tumor tissue biopsies
US20050260639A1 (en) * 2002-09-30 2005-11-24 Oncotherapy Science, Inc. Method for diagnosing pancreatic cancer
CN1703524B (en) * 2002-09-30 2010-04-07 肿瘤疗法科学股份有限公司 Genes and polypeptides relating to human pancreatic cancer
EP1570080A4 (en) 2002-11-15 2006-03-01 Genomic Health Inc Gene expression profiling of egfr positive cancer
CN1726395A (en) * 2002-12-17 2006-01-25 北京诺赛基因组研究中心有限公司 Specific markers for pancreatic cancer
AU2003294828A1 (en) * 2002-12-17 2004-07-09 Sinogenomax Co. Ltd. Chinese National Human Genomecenter Specific markers for pancreatic cancer
US8014952B2 (en) 2002-12-18 2011-09-06 Queen Elizabeth Hospital Serum biomarkers in lung cancer
US20050181375A1 (en) 2003-01-10 2005-08-18 Natasha Aziz Novel methods of diagnosis of metastatic cancer, compositions and methods of screening for modulators of metastatic cancer
US20040231909A1 (en) 2003-01-15 2004-11-25 Tai-Yang Luh Motorized vehicle having forward and backward differential structure
AU2003900747A0 (en) 2003-02-18 2003-03-06 Garvan Institute Of Medical Research Diagnosis and treatment of pancreatic cancer
CA2516553C (en) 2003-02-20 2013-04-16 Genomic Health, Inc. Use of intronic rna to measure gene expression
WO2004075713A2 (en) 2003-02-26 2004-09-10 Mount Sinai Hospital Multiple marker assay for detection of ovarian cancer
WO2004099432A2 (en) 2003-05-02 2004-11-18 The Johns Hopkins University Identification of biomarkers for detecting pancreatic cancer
US20060019256A1 (en) * 2003-06-09 2006-01-26 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
CN1852974A (en) * 2003-06-09 2006-10-25 密歇根大学董事会 Compositions and methods for treating and diagnosing cancer
DK1641810T4 (en) 2003-06-24 2017-07-03 Genomic Health Inc Predicting the likelihood of cancer recurrence
ES2905579T3 (en) 2003-07-10 2022-04-11 Genomic Health Inc Expression profiling algorithm and test for prognosis of breast cancer relapse
AU2004264948A1 (en) 2003-08-15 2005-02-24 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Multifactorial assay for cancer detection
US7807392B1 (en) 2003-09-15 2010-10-05 Celera Corporation Lung disease targets and uses thereof
EP1682904A2 (en) 2003-11-04 2006-07-26 Roche Diagnostics GmbH Method for distinguishing who classified aml subtypes
US20050181451A1 (en) 2004-02-12 2005-08-18 Bates Harold M. Detection of asymptomatic coronary artery disease using atherogenic proteins and acute phase reactants
EP2026071B1 (en) 2004-02-19 2013-07-31 Yale University Identification of cancer protein biomarkers using proteomic techniques
US8019552B2 (en) 2004-03-05 2011-09-13 The Netherlands Cancer Institute Classification of breast cancer patients using a combination of clinical criteria and informative genesets
CA2848463A1 (en) 2004-04-09 2005-10-27 Genomic Health, Inc. Gene expression markers for predicting response to chemotherapy
ES2367311T3 (en) 2004-04-15 2011-11-02 University Of Florida Research Foundation, Inc. MAP-2 PROTEOLYTIC DEGRADATION PRODUCTS AS DIAGNOSTIC BIOMARCATORS FOR NEURAL INJURIES.
WO2005103281A2 (en) 2004-04-26 2005-11-03 Children's Medical Center Corporation Platelet biomarkers for the detection of disease
WO2006022643A1 (en) 2004-07-26 2006-03-02 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for detecting pancreatic disease
WO2006022895A2 (en) 2004-08-02 2006-03-02 Children's Medical Center Corporation Platelet biomarkers for cancer
JP2006053113A (en) 2004-08-16 2006-02-23 Medical Proteoscope Co Ltd Method and kit for diagnosing pulmonary adenocarcinoma lymph node metastasis
JP4939425B2 (en) 2004-11-05 2012-05-23 ジェノミック ヘルス, インコーポレイテッド Molecular indicators of prognosis and prediction of treatment response in breast cancer
AU2005304824B2 (en) 2004-11-05 2011-12-22 Genomic Health, Inc. Predicting response to chemotherapy using gene expression markers
US7862995B2 (en) 2004-12-10 2011-01-04 Targeted Molecular Diagnostics Methods and materials for predicting responsiveness to treatment with dual tyrosine kinase inhibitor
US8632983B2 (en) 2005-04-15 2014-01-21 Van Andel Research Institute Biomarkers for pancreatic cancer and diagnostic methods
US20070099209A1 (en) 2005-06-13 2007-05-03 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
EP1904649A2 (en) 2005-07-18 2008-04-02 Epigenomics AG Compositions and methods for cancer diagnostics comprising pan-cancer markers
US7521195B1 (en) 2005-07-21 2009-04-21 Celera Corporation Lung disease targets and uses thereof
EP2295571A1 (en) 2005-07-27 2011-03-16 Oncotherapy Science, Inc. Method of diagnosing small cell lung cancer
US20080305962A1 (en) 2005-07-29 2008-12-11 Ralph Markus Wirtz Methods and Kits for the Prediction of Therapeutic Success, Recurrence Free and Overall Survival in Cancer Therapies
US7582441B1 (en) 2005-10-17 2009-09-01 Celera Corporation Methods and compositions for treating and diagnosing disease
EP1777523A1 (en) * 2005-10-19 2007-04-25 INSERM (Institut National de la Santé et de la Recherche Médicale) An in vitro method for the prognosis of progression of a cancer and of the outcome in a patient and means for performing said method
US8329408B2 (en) 2005-10-31 2012-12-11 Bayer Healthcare Llc Methods for prognosis and monitoring cancer therapy
JP2009516178A (en) 2005-11-10 2009-04-16 ユニバーシティー オブ ケンタッキー Lung cancer diagnostic assay
US8445198B2 (en) 2005-12-01 2013-05-21 Medical Prognosis Institute Methods, kits and devices for identifying biomarkers of treatment response and use thereof to predict treatment efficacy
US8014957B2 (en) 2005-12-15 2011-09-06 Fred Hutchinson Cancer Research Center Genes associated with progression and response in chronic myeloid leukemia and uses thereof
US20070178504A1 (en) 2005-12-22 2007-08-02 Tracey Colpitts Methods and marker combinations for screening for predisposition to lung cancer
NZ593224A (en) 2006-01-11 2012-10-26 Genomic Health Inc Gene expression markers (fap) for colorectal cancer prognosis
AU2007211085A1 (en) 2006-01-27 2007-08-09 Tripath Imaging, Inc. Methods for identifying patients with an increased likelihood of having ovarian cancer and compositions therefor
CA2641315A1 (en) * 2006-02-06 2007-08-16 Tethys Bioscience, Inc. Osteoporosis associated markers and methods of use thereof
CA2645125A1 (en) * 2006-03-02 2007-09-13 Oncotherapy Science, Inc. Methods for diagnosing pancreatic cancer using reg4 protein
WO2007109571A2 (en) 2006-03-17 2007-09-27 Prometheus Laboratories, Inc. Methods of predicting and monitoring tyrosine kinase inhibitor therapy
US7888019B2 (en) 2006-03-31 2011-02-15 Genomic Health, Inc. Genes involved estrogen metabolism
US20100255518A1 (en) 2006-04-04 2010-10-07 Goix Philippe J Highly sensitive system and methods for analysis of troponin
WO2007146229A2 (en) 2006-06-07 2007-12-21 Tethys Bioscience, Inc. Markers associated with arteriovascular events and methods of use thereof
WO2008003024A2 (en) 2006-06-28 2008-01-03 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Method and composition for diagnosing endometrial cancer
EP2090665A2 (en) 2006-10-20 2009-08-19 Exiqon A/S Novel human microRNAs associated with cancer
AU2007322206A1 (en) 2006-11-13 2008-05-29 Source Precision Medicine, Inc. Gene expression profiling for identification, monitoring, and treatment of lung cancer
WO2008086182A2 (en) 2007-01-04 2008-07-17 University Of Rochester Use of gene signatures to design novel cancer treatment regimens
US7947447B2 (en) 2007-01-16 2011-05-24 Somalogic, Inc. Method for generating aptamers with improved off-rates
KR100846354B1 (en) 2007-03-21 2008-07-15 (주) 프로탄바이오 Diagnostic biomarker for lung adenocarcinoma isolated from serum glycoproteins
ES2442919T3 (en) * 2007-03-27 2014-02-14 Immunovia Ab Signature / protein markers for the detection of adenocarcinoma
US20080274481A1 (en) 2007-03-28 2008-11-06 Vermillion, Inc. Methods for diagnosing ovarian cancer
EP2515116A1 (en) 2007-05-18 2012-10-24 Duke University Serum biomarkers for the early detection of lung cancer
JP2010530217A (en) * 2007-05-29 2010-09-09 プレジデント アンド フェローズ オブ ハーバード カレッジ Molecules involved in the regulation of osteogenic and osteoclast activity and methods of use
GB0717637D0 (en) 2007-09-10 2007-10-17 Univ Leiden Future cardiac event biomarkers
US8541183B2 (en) 2007-09-11 2013-09-24 Cancer Prevention And Cure, Ltd. Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof
WO2009036123A1 (en) 2007-09-11 2009-03-19 Cancer Prevention And Cure, Ltd. Method of identifying biomarkers in human serum indicative of pathologies of human lung tissues
US20100267041A1 (en) * 2007-09-14 2010-10-21 Predictive Biosciences, Inc. Serial analysis of biomarkers for disease diagnosis
AU2008302526A1 (en) 2007-09-18 2009-03-26 Board Of Regents Of The University Of Texas System Detection of saliva proteins modulated secondary to ductal carcinoma in situ of the breast
EP2728017B1 (en) 2007-11-19 2016-08-24 Celera Corporation Lung cancer markers and uses thereof
EP2238455A4 (en) 2008-01-18 2011-03-02 Vatrix Medical Inc Diagnostic biomarkers for vascular aneurysm
GB0803192D0 (en) 2008-02-22 2008-04-02 Mubio Products Bv SCLC biomarker panel
US8067178B2 (en) 2008-03-14 2011-11-29 Genomic Health, Inc. Gene expression markers for prediction of patient response to chemotherapy
CN102057680A (en) * 2008-07-04 2011-05-11 株式会社东芝 Dynamic image encoding/decoding method and device
US20120143805A1 (en) 2008-09-09 2012-06-07 Somalogic, Inc. Cancer Biomarkers and Uses Thereof
US10359425B2 (en) 2008-09-09 2019-07-23 Somalogic, Inc. Lung cancer biomarkers and uses thereof
MX2011002322A (en) 2008-09-09 2011-05-10 Somalogic Inc Lung cancer biomarkers and uses thereof.
US8580520B2 (en) * 2008-09-15 2013-11-12 Herlev Hospital YKL-40 as a marker for gastrointestinal cancers
US20120165217A1 (en) 2008-10-06 2012-06-28 Somalogic, Inc. Cancer Biomarkers and Uses Thereof
CA2737004A1 (en) 2008-10-06 2010-04-15 Somalogic, Inc. Ovarian cancer biomarkers and uses thereof
US20100221752A2 (en) 2008-10-06 2010-09-02 Somalogic, Inc. Ovarian Cancer Biomarkers and Uses Thereof
WO2010049538A1 (en) 2008-10-30 2010-05-06 Centre de Recherche Public de la Santé Biomarkers
CA3153682A1 (en) 2008-11-17 2010-05-20 Veracyte, Inc. Methods and compositions of molecular profiling for disease diagnostics
EP2366162A1 (en) 2008-11-18 2011-09-21 Collabrx, Inc. Individualized cancer treatment
US20110236903A1 (en) 2008-12-04 2011-09-29 Mcclelland Michael Materials and methods for determining diagnosis and prognosis of prostate cancer
AU2010259022B2 (en) 2009-06-08 2016-05-12 Singulex, Inc. Highly sensitive biomarker panels
ES2623633T3 (en) 2009-06-09 2017-07-11 Gendiag.Exe, S.L. Risk markers for cardiovascular disease
AU2010260152A1 (en) 2009-06-15 2012-02-02 Cardiodx, Inc. Determination of coronary artery disease risk.
AU2010284199A1 (en) 2009-08-19 2012-04-05 The Cleveland Clinic Foundation Marker detection for characterizing the risk of cardiovascular disease or complications thereof
WO2011035433A1 (en) 2009-09-23 2011-03-31 University Health Network Selected strains on serum-free growth media for proteomics analysis of lung cancer biomarkers
EP2483697B2 (en) * 2009-10-01 2017-07-05 Phenomenome Discoveries Inc. Method to diagnose pancreatic cancer
US9683996B2 (en) 2009-10-22 2017-06-20 The Regents Of The University Of California Assessment of solid tumor burden
WO2011059721A1 (en) 2009-10-29 2011-05-19 Tethys Bioscience, Inc. Protein and lipid biomarkers providing consistent improvement to the prediction of type 2 diabetes
CN102858999A (en) * 2009-12-01 2013-01-02 简要生物科学有限公司 Classification of cancers
AU2010328019A1 (en) 2009-12-09 2012-06-28 Aviir, Inc. Biomarker assay for diagnosis and classification of cardiovascular disease
NZ705645A (en) 2010-01-11 2016-05-27 Genomic Health Inc Method to use gene expression to determine likelihood of clinical outcome of renal cancer
US9404926B2 (en) 2010-01-29 2016-08-02 H. Lee Moffitt Cancer Center And Research Institute, Inc. Immune gene signatures in cancer
US9689039B2 (en) 2010-02-10 2017-06-27 The Regents Of The University Of California Salivary biomarkers for lung cancer detection
WO2011100472A1 (en) 2010-02-10 2011-08-18 The Regents Of The University Of California Salivary transcriptomic and proteomic biomarkers for breast cancer detection
EP2542696B1 (en) 2010-03-01 2016-09-28 Caris Life Sciences Switzerland Holdings GmbH Biomarkers for theranostics
AU2011237669B2 (en) 2010-04-06 2016-09-08 Caris Life Sciences Switzerland Holdings Gmbh Circulating biomarkers for disease
CN104777313B (en) 2010-07-09 2017-09-26 私募蛋白质体公司 Lung cancer biomarkers and application thereof
WO2012021795A2 (en) 2010-08-13 2012-02-16 Somalogic, Inc. Pancreatic cancer biomarkers and uses thereof
CA2809282C (en) 2010-09-27 2017-09-12 Somalogic, Inc. Mesothelioma biomarkers and uses thereof
CN110444287B (en) 2011-04-29 2024-02-06 癌症预防和治疗有限公司 Methods for identifying and diagnosing pulmonary diseases using a classification system and kits therefor
CA2843756A1 (en) 2011-08-22 2013-02-28 Somalogic, Inc. Renal cell carcinoma biomarkers and uses thereof
RU2651708C2 (en) 2011-09-30 2018-04-23 Сомалоджик, Инк. Cardiovascular risk event prediction and uses thereof
US9434779B2 (en) 2012-03-19 2016-09-06 The Brigham And Women's Hospital, Inc. Growth differentiation factor 11 (GDF-11) for treatment of diastolic heart failure
EP3071588A4 (en) 2013-11-21 2017-08-02 Somalogic, Inc. Cytidine-5-carboxamide modified nucleotide compositions and methods related thereto

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