JP2013541564A5 - - Google Patents
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- Publication number
- JP2013541564A5 JP2013541564A5 JP2013537002A JP2013537002A JP2013541564A5 JP 2013541564 A5 JP2013541564 A5 JP 2013541564A5 JP 2013537002 A JP2013537002 A JP 2013537002A JP 2013537002 A JP2013537002 A JP 2013537002A JP 2013541564 A5 JP2013541564 A5 JP 2013541564A5
- Authority
- JP
- Japan
- Prior art keywords
- noroxymorphone
- mixing
- reaction
- mixture
- optionally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41040510P | 2010-11-05 | 2010-11-05 | |
| US61/410,405 | 2010-11-05 | ||
| DKPA201001007 | 2010-11-05 | ||
| DKPA201001007 | 2010-11-05 | ||
| US201161489701P | 2011-05-25 | 2011-05-25 | |
| DKPA201100396 | 2011-05-25 | ||
| DKPA201100396 | 2011-05-25 | ||
| US61/489,701 | 2011-05-25 | ||
| PCT/DK2011/000128 WO2012059103A1 (en) | 2010-11-05 | 2011-11-04 | Method for the manufacturing of naltrexone |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016125389A Division JP6215399B2 (ja) | 2010-11-05 | 2016-06-24 | ナルトレキソンの製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013541564A JP2013541564A (ja) | 2013-11-14 |
| JP2013541564A5 true JP2013541564A5 (https=) | 2014-12-18 |
| JP6246589B2 JP6246589B2 (ja) | 2017-12-13 |
Family
ID=45001588
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013537002A Active JP6246589B2 (ja) | 2010-11-05 | 2011-11-04 | ナルトレキソンの製造方法 |
| JP2016125389A Active JP6215399B2 (ja) | 2010-11-05 | 2016-06-24 | ナルトレキソンの製造方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016125389A Active JP6215399B2 (ja) | 2010-11-05 | 2016-06-24 | ナルトレキソンの製造方法 |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP2635586B1 (https=) |
| JP (2) | JP6246589B2 (https=) |
| AP (1) | AP3415A (https=) |
| AU (1) | AU2011325563B2 (https=) |
| CA (1) | CA2815093C (https=) |
| CY (1) | CY1118742T1 (https=) |
| DK (1) | DK2635586T3 (https=) |
| EA (1) | EA022266B1 (https=) |
| ES (1) | ES2620660T3 (https=) |
| HR (1) | HRP20170379T1 (https=) |
| HU (1) | HUE033596T2 (https=) |
| LT (1) | LT2635586T (https=) |
| ME (1) | ME02621B (https=) |
| MX (1) | MX2013005009A (https=) |
| PL (1) | PL2635586T3 (https=) |
| PT (1) | PT2635586T (https=) |
| RS (1) | RS55777B1 (https=) |
| SI (1) | SI2635586T1 (https=) |
| SM (1) | SMT201700177T1 (https=) |
| WO (1) | WO2012059103A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140005217A1 (en) | 2012-06-27 | 2014-01-02 | H. Lundbeck A/S | Nalmefene for reduction of alcohol consumption in specific target populations |
| AR096851A1 (es) | 2013-07-11 | 2016-02-03 | H Lundbeck As | Sales que no forman hidratos ni solvatos de nalmefeno |
| MX368870B (es) | 2013-12-20 | 2019-10-21 | H Lundbeck As | Uso de un antagonista de receptores de opioides con actividad kappa y vortioxetina para el tratamiento de trastorno depresivo con características melancólicas. |
| EP3134090B1 (en) | 2014-04-22 | 2019-06-05 | Otsuka Pharmaceutical Co., Ltd. | Combination of brexpiprazole and nalmefene and use thereof for treating substance-related disorders |
| US9701688B2 (en) * | 2014-05-05 | 2017-07-11 | Noramco, Inc. | Process for the preparation of opioid compounds |
| US9701687B2 (en) * | 2014-05-05 | 2017-07-11 | Noramco, Inc. | Process for the preparation of opioid compounds |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4535157A (en) | 1983-11-01 | 1985-08-13 | Key Pharmaceuticals, Inc. | Process for making 6-desoxy-6-methylenenaloxone and 6-desoxy-6-methylenenaltrexone |
| US4751307A (en) | 1985-01-17 | 1988-06-14 | Mallinckrodt, Inc. | Wittig-reaction processes |
| CA2067200C (en) * | 1989-10-16 | 1998-06-30 | Kenner C. Rice | Total synthesis of northebaine, normorphine, noroxymorphone enantiomers and derivatives via n-nor intermediates |
| FR2906252B1 (fr) * | 2006-09-21 | 2008-11-28 | Sanofi Aventis Sa | Procede de preparation d'halogenures de n-aklyl naltrexone |
| WO2008138383A1 (de) * | 2007-05-16 | 2008-11-20 | Cilag Ag | Verfahren zur herstellung von n-methylnaltrexonbromid |
| CA2738246C (en) * | 2008-09-30 | 2017-09-05 | Mallinckrodt Inc. | Processes for the alkylation of secondary amine groups of morphinan derivatives |
| ES2564006T3 (es) | 2009-05-25 | 2016-03-17 | H. Lundbeck A/S | Preparación de hidrocloruro de nalmefeno a partir de naltrexona |
-
2011
- 2011-11-04 SM SM20170177T patent/SMT201700177T1/it unknown
- 2011-11-04 WO PCT/DK2011/000128 patent/WO2012059103A1/en not_active Ceased
- 2011-11-04 LT LTEP11785301.0T patent/LT2635586T/lt unknown
- 2011-11-04 RS RS20170244A patent/RS55777B1/sr unknown
- 2011-11-04 AP AP2013006897A patent/AP3415A/xx active
- 2011-11-04 PT PT117853010T patent/PT2635586T/pt unknown
- 2011-11-04 CA CA2815093A patent/CA2815093C/en active Active
- 2011-11-04 DK DK11785301.0T patent/DK2635586T3/en active
- 2011-11-04 SI SI201131131A patent/SI2635586T1/sl unknown
- 2011-11-04 ES ES11785301.0T patent/ES2620660T3/es active Active
- 2011-11-04 AU AU2011325563A patent/AU2011325563B2/en not_active Ceased
- 2011-11-04 HR HRP20170379TT patent/HRP20170379T1/hr unknown
- 2011-11-04 ME MEP-2017-57A patent/ME02621B/me unknown
- 2011-11-04 PL PL11785301T patent/PL2635586T3/pl unknown
- 2011-11-04 MX MX2013005009A patent/MX2013005009A/es active IP Right Grant
- 2011-11-04 JP JP2013537002A patent/JP6246589B2/ja active Active
- 2011-11-04 EA EA201390658A patent/EA022266B1/ru not_active IP Right Cessation
- 2011-11-04 EP EP11785301.0A patent/EP2635586B1/en active Active
- 2011-11-04 HU HUE11785301A patent/HUE033596T2/hu unknown
-
2016
- 2016-06-24 JP JP2016125389A patent/JP6215399B2/ja active Active
-
2017
- 2017-03-17 CY CY20171100341T patent/CY1118742T1/el unknown
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