JP2013541564A5 - - Google Patents

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Publication number
JP2013541564A5
JP2013541564A5 JP2013537002A JP2013537002A JP2013541564A5 JP 2013541564 A5 JP2013541564 A5 JP 2013541564A5 JP 2013537002 A JP2013537002 A JP 2013537002A JP 2013537002 A JP2013537002 A JP 2013537002A JP 2013541564 A5 JP2013541564 A5 JP 2013541564A5
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JP
Japan
Prior art keywords
noroxymorphone
mixing
reaction
mixture
optionally
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013537002A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013541564A (ja
JP6246589B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/DK2011/000128 external-priority patent/WO2012059103A1/en
Publication of JP2013541564A publication Critical patent/JP2013541564A/ja
Publication of JP2013541564A5 publication Critical patent/JP2013541564A5/ja
Application granted granted Critical
Publication of JP6246589B2 publication Critical patent/JP6246589B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2013537002A 2010-11-05 2011-11-04 ナルトレキソンの製造方法 Active JP6246589B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US41040510P 2010-11-05 2010-11-05
DKPA201001007 2010-11-05
US61/410,405 2010-11-05
DKPA201001007 2010-11-05
US201161489701P 2011-05-25 2011-05-25
US61/489,701 2011-05-25
DKPA201100396 2011-05-25
DKPA201100396 2011-05-25
PCT/DK2011/000128 WO2012059103A1 (en) 2010-11-05 2011-11-04 Method for the manufacturing of naltrexone

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016125389A Division JP6215399B2 (ja) 2010-11-05 2016-06-24 ナルトレキソンの製造方法

Publications (3)

Publication Number Publication Date
JP2013541564A JP2013541564A (ja) 2013-11-14
JP2013541564A5 true JP2013541564A5 (https=) 2014-12-18
JP6246589B2 JP6246589B2 (ja) 2017-12-13

Family

ID=45001588

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2013537002A Active JP6246589B2 (ja) 2010-11-05 2011-11-04 ナルトレキソンの製造方法
JP2016125389A Active JP6215399B2 (ja) 2010-11-05 2016-06-24 ナルトレキソンの製造方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2016125389A Active JP6215399B2 (ja) 2010-11-05 2016-06-24 ナルトレキソンの製造方法

Country Status (20)

Country Link
EP (1) EP2635586B1 (https=)
JP (2) JP6246589B2 (https=)
AP (1) AP3415A (https=)
AU (1) AU2011325563B2 (https=)
CA (1) CA2815093C (https=)
CY (1) CY1118742T1 (https=)
DK (1) DK2635586T3 (https=)
EA (1) EA022266B1 (https=)
ES (1) ES2620660T3 (https=)
HR (1) HRP20170379T1 (https=)
HU (1) HUE033596T2 (https=)
LT (1) LT2635586T (https=)
ME (1) ME02621B (https=)
MX (1) MX2013005009A (https=)
PL (1) PL2635586T3 (https=)
PT (1) PT2635586T (https=)
RS (1) RS55777B1 (https=)
SI (1) SI2635586T1 (https=)
SM (1) SMT201700177T1 (https=)
WO (1) WO2012059103A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140005217A1 (en) 2012-06-27 2014-01-02 H. Lundbeck A/S Nalmefene for reduction of alcohol consumption in specific target populations
AR096851A1 (es) 2013-07-11 2016-02-03 H Lundbeck As Sales que no forman hidratos ni solvatos de nalmefeno
ES2694352T3 (es) 2013-12-20 2018-12-20 H. Lundbeck A/S Uso de un antagonista del receptor opioide con actividad kappa, y vortioxetina para el tratamiento del trastorno depresivo con características melancólicas
MX2016013889A (es) 2014-04-22 2017-03-09 Otsuka Pharma Co Ltd Medicamento.
US9701687B2 (en) * 2014-05-05 2017-07-11 Noramco, Inc. Process for the preparation of opioid compounds
US9701688B2 (en) * 2014-05-05 2017-07-11 Noramco, Inc. Process for the preparation of opioid compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535157A (en) 1983-11-01 1985-08-13 Key Pharmaceuticals, Inc. Process for making 6-desoxy-6-methylenenaloxone and 6-desoxy-6-methylenenaltrexone
US4751307A (en) 1985-01-17 1988-06-14 Mallinckrodt, Inc. Wittig-reaction processes
ATE178329T1 (de) * 1989-10-16 1999-04-15 Us Health Totale synthese von northebain-, normorphin-, noroxymorphon-enantiomeren und -derivaten via n- nor-zwischenverbindungen
FR2906252B1 (fr) 2006-09-21 2008-11-28 Sanofi Aventis Sa Procede de preparation d'halogenures de n-aklyl naltrexone
WO2008138383A1 (de) 2007-05-16 2008-11-20 Cilag Ag Verfahren zur herstellung von n-methylnaltrexonbromid
WO2010039209A2 (en) * 2008-09-30 2010-04-08 Mallinckrodt Inc. Processes for the synthesis of tertiary amines
UA106752C2 (uk) 2009-05-25 2014-10-10 Х. Луннбек А/С Одержання налмефену гідрохлориду з налтрексону

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