JP2013536156A5 - - Google Patents
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- Publication number
- JP2013536156A5 JP2013536156A5 JP2013503918A JP2013503918A JP2013536156A5 JP 2013536156 A5 JP2013536156 A5 JP 2013536156A5 JP 2013503918 A JP2013503918 A JP 2013503918A JP 2013503918 A JP2013503918 A JP 2013503918A JP 2013536156 A5 JP2013536156 A5 JP 2013536156A5
- Authority
- JP
- Japan
- Prior art keywords
- lipoic acid
- wound dressing
- acid derivative
- scaffold
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010052428 Wound Diseases 0.000 claims 32
- 208000027418 Wounds and injury Diseases 0.000 claims 32
- AGBQKNBQESQNJD-UHFFFAOYSA-N lipoic acid Chemical class OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 claims 32
- 239000000758 substrate Substances 0.000 claims 23
- 238000000034 method Methods 0.000 claims 18
- 239000000203 mixture Substances 0.000 claims 17
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 claims 15
- 102000035195 Peptidases Human genes 0.000 claims 13
- 108091005804 Peptidases Proteins 0.000 claims 13
- 239000000463 material Substances 0.000 claims 10
- 125000005915 C6-C14 aryl group Chemical group 0.000 claims 9
- 235000019136 lipoic acid Nutrition 0.000 claims 7
- 229920002635 polyurethane Polymers 0.000 claims 7
- 239000004814 polyurethane Substances 0.000 claims 7
- 229960002663 thioctic acid Drugs 0.000 claims 7
- 125000005210 alkyl ammonium group Chemical group 0.000 claims 6
- 150000001413 amino acids Chemical class 0.000 claims 6
- 239000002738 chelating agent Substances 0.000 claims 5
- 230000001419 dependent effect Effects 0.000 claims 5
- 102000008186 Collagen Human genes 0.000 claims 4
- 108010035532 Collagen Proteins 0.000 claims 4
- 108010010803 Gelatin Proteins 0.000 claims 4
- 229920001436 collagen Polymers 0.000 claims 4
- 239000006260 foam Substances 0.000 claims 4
- 229920000159 gelatin Polymers 0.000 claims 4
- 239000008273 gelatin Substances 0.000 claims 4
- 235000019322 gelatine Nutrition 0.000 claims 4
- 235000011852 gelatine desserts Nutrition 0.000 claims 4
- IZFHEQBZOYJLPK-SSDOTTSWSA-N (R)-dihydrolipoic acid Chemical compound OC(=O)CCCC[C@@H](S)CCS IZFHEQBZOYJLPK-SSDOTTSWSA-N 0.000 claims 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims 3
- 239000003242 anti bacterial agent Substances 0.000 claims 3
- 238000001035 drying Methods 0.000 claims 3
- 239000012530 fluid Substances 0.000 claims 3
- 239000003102 growth factor Substances 0.000 claims 3
- 239000000137 peptide hydrolase inhibitor Substances 0.000 claims 3
- 239000003755 preservative agent Substances 0.000 claims 3
- 230000002335 preservative effect Effects 0.000 claims 3
- 235000018102 proteins Nutrition 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- AGBQKNBQESQNJD-SSDOTTSWSA-N (R)-lipoic acid Chemical group OC(=O)CCCC[C@@H]1CCSS1 AGBQKNBQESQNJD-SSDOTTSWSA-N 0.000 claims 2
- VAZJLPXFVQHDFB-UHFFFAOYSA-N 1-(diaminomethylidene)-2-hexylguanidine Polymers CCCCCCN=C(N)N=C(N)N VAZJLPXFVQHDFB-UHFFFAOYSA-N 0.000 claims 2
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 claims 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical group OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims 2
- 229920002413 Polyhexanide Polymers 0.000 claims 2
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 claims 2
- 239000004599 antimicrobial Substances 0.000 claims 2
- 229960000686 benzalkonium chloride Drugs 0.000 claims 2
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 claims 2
- 229960003260 chlorhexidine Drugs 0.000 claims 2
- 230000002757 inflammatory effect Effects 0.000 claims 2
- 239000011148 porous material Substances 0.000 claims 2
- 229910052709 silver Inorganic materials 0.000 claims 2
- 239000004332 silver Substances 0.000 claims 2
- 229960003500 triclosan Drugs 0.000 claims 2
- 230000029663 wound healing Effects 0.000 claims 2
- 102000009027 Albumins Human genes 0.000 claims 1
- 108010088751 Albumins Proteins 0.000 claims 1
- 102000011632 Caseins Human genes 0.000 claims 1
- 108010076119 Caseins Proteins 0.000 claims 1
- 102000016942 Elastin Human genes 0.000 claims 1
- 108010014258 Elastin Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 108010049003 Fibrinogen Proteins 0.000 claims 1
- 102000008946 Fibrinogen Human genes 0.000 claims 1
- 102000016359 Fibronectins Human genes 0.000 claims 1
- 108010067306 Fibronectins Proteins 0.000 claims 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 1
- 108010076876 Keratins Proteins 0.000 claims 1
- 102000011782 Keratins Human genes 0.000 claims 1
- 102000014171 Milk Proteins Human genes 0.000 claims 1
- 108010011756 Milk Proteins Proteins 0.000 claims 1
- 108010073771 Soybean Proteins Proteins 0.000 claims 1
- 241000209140 Triticum Species 0.000 claims 1
- 235000021307 Triticum Nutrition 0.000 claims 1
- 240000008042 Zea mays Species 0.000 claims 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims 1
- 239000000853 adhesive Substances 0.000 claims 1
- 230000001070 adhesive effect Effects 0.000 claims 1
- 210000001124 body fluid Anatomy 0.000 claims 1
- 239000010839 body fluid Substances 0.000 claims 1
- 239000005018 casein Substances 0.000 claims 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims 1
- 235000021240 caseins Nutrition 0.000 claims 1
- 230000015556 catabolic process Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 235000005822 corn Nutrition 0.000 claims 1
- 230000006837 decompression Effects 0.000 claims 1
- 238000006731 degradation reaction Methods 0.000 claims 1
- 229920002549 elastin Polymers 0.000 claims 1
- 229940012952 fibrinogen Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000003825 pressing Methods 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
- 159000000000 sodium salts Chemical class 0.000 claims 1
- 229940001941 soy protein Drugs 0.000 claims 1
- 230000001954 sterilising effect Effects 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/757,562 US8632512B2 (en) | 2010-04-09 | 2010-04-09 | Apparatuses, methods, and compositions for the treatment and prophylaxis of chronic wounds |
| US12/757,562 | 2010-04-09 | ||
| PCT/US2011/031441 WO2011127188A2 (en) | 2010-04-09 | 2011-04-06 | Apparatuses, methods, and compositions for the treatment and prophylaxis of chronic wounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016085736A Division JP6189473B2 (ja) | 2010-04-09 | 2016-04-22 | 慢性創傷を治療及び予防するための装置、方法、及び組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013536156A JP2013536156A (ja) | 2013-09-19 |
| JP2013536156A5 true JP2013536156A5 (cg-RX-API-DMAC10.html) | 2014-05-22 |
| JP5988309B2 JP5988309B2 (ja) | 2016-09-07 |
Family
ID=44059227
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013503918A Active JP5988309B2 (ja) | 2010-04-09 | 2011-04-06 | 慢性創傷を治療及び予防するための装置、方法、及び組成物 |
| JP2016085736A Expired - Fee Related JP6189473B2 (ja) | 2010-04-09 | 2016-04-22 | 慢性創傷を治療及び予防するための装置、方法、及び組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016085736A Expired - Fee Related JP6189473B2 (ja) | 2010-04-09 | 2016-04-22 | 慢性創傷を治療及び予防するための装置、方法、及び組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8632512B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP2555805B1 (cg-RX-API-DMAC10.html) |
| JP (2) | JP5988309B2 (cg-RX-API-DMAC10.html) |
| CN (2) | CN105126156A (cg-RX-API-DMAC10.html) |
| AU (1) | AU2011237638B2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2790559A1 (cg-RX-API-DMAC10.html) |
| TW (1) | TW201141548A (cg-RX-API-DMAC10.html) |
| WO (1) | WO2011127188A2 (cg-RX-API-DMAC10.html) |
Families Citing this family (68)
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| US11298453B2 (en) | 2003-10-28 | 2022-04-12 | Smith & Nephew Plc | Apparatus and method for wound cleansing with actives |
| GB0808376D0 (en) | 2008-05-08 | 2008-06-18 | Bristol Myers Squibb Co | Wound dressing |
| GB0817796D0 (en) | 2008-09-29 | 2008-11-05 | Convatec Inc | wound dressing |
| WO2011103462A1 (en) | 2010-02-18 | 2011-08-25 | Osiris Therapeutics, Inc. | Methods of manufacture of immunocompatible amniotic membrane products |
| GB201020236D0 (en) | 2010-11-30 | 2011-01-12 | Convatec Technologies Inc | A composition for detecting biofilms on viable tissues |
| EP4162968A1 (en) | 2010-12-08 | 2023-04-12 | ConvaTec Technologies Inc. | System for removing exudates from a wound site |
| CN103347561B (zh) | 2010-12-08 | 2016-09-07 | 康沃特克科技公司 | 用于评估伤口分泌液的集成系统 |
| EP2648794B1 (en) | 2010-12-08 | 2019-08-28 | ConvaTec Technologies Inc. | Wound exudate system accessory |
| US8597264B2 (en) | 2011-03-24 | 2013-12-03 | Kci Licensing, Inc. | Apparatuses, methods, and compositions for the treatment and prophylaxis of chronic wounds |
| EP3851131A1 (en) | 2011-05-31 | 2021-07-21 | LifeCell Corporation | Adipose tissue matrices |
| GB201115182D0 (en) | 2011-09-02 | 2011-10-19 | Trio Healthcare Ltd | Skin contact material |
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| CN102492109A (zh) * | 2011-11-28 | 2012-06-13 | 西安科技大学 | 一种可生物降解高回弹软质聚氨酯泡沫塑料及其制备方法 |
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| JP6670827B2 (ja) | 2014-05-16 | 2020-03-25 | スリーエム イノベイティブ プロパティズ カンパニー | 一体化させたエラストマー材料を備える多孔性エラストマー材料を含む物品、並びにその製造方法 |
| AU2015302021B2 (en) * | 2014-08-11 | 2019-05-30 | 3M Innovative Properties Company | Protease modulating wound interface layer for use with negative pressure wound therapy |
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| EP3436820A2 (en) | 2016-03-30 | 2019-02-06 | Qualizyme Diagnostics GmbH&Co KG | Detecting microbial infection in wounds |
| ES2904480T3 (es) | 2016-03-30 | 2022-04-05 | Convatec Technologies Inc | Detección de infecciones microbianas en heridas |
| GB201608099D0 (en) | 2016-05-09 | 2016-06-22 | Convatec Technologies Inc | Negative pressure wound dressing |
| ES2841427T3 (es) | 2016-07-05 | 2021-07-08 | Lifecell Corp | Matrices de tejido que incorporan múltiples tipos de tejido |
| JP2019525799A (ja) | 2016-07-08 | 2019-09-12 | コンバテック・テクノロジーズ・インコーポレイテッドＣｏｎｖａｔｅｃ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ | 流体収集装置 |
| AU2017292881B2 (en) | 2016-07-08 | 2022-03-17 | Convatec Technologies Inc. | Flexible negative pressure system |
| BR112019000316A2 (pt) | 2016-07-08 | 2019-04-16 | Convatec Technologies Inc. | detecção de fluxo de fluido |
| CN107789660A (zh) * | 2016-08-31 | 2018-03-13 | 杜建 | 一种用于皮肤及软组织损伤的医用敷料 |
| US20200038248A1 (en) * | 2016-10-05 | 2020-02-06 | Temple University- Of The Commonwealth System Of Higher Education | Negative Pressure Enhanced Cellular Infiltration |
| WO2018226627A1 (en) | 2017-06-07 | 2018-12-13 | Kci Licensing, Inc. | Composite dressings for improved granulation and reduced maceration with negative-pressure treatment |
| WO2018226691A1 (en) | 2017-06-07 | 2018-12-13 | Kci Licensing, Inc. | Methods for manufacturing and assembling dual material tissue interface for negative-pressure therapy |
| EP3634330A1 (en) | 2017-06-07 | 2020-04-15 | KCI Licensing, Inc. | Composite dressings for improved granulation reduced maceration with negative-pressure treatment |
| BR112019025760A2 (pt) | 2017-06-07 | 2020-06-23 | Kci Licensing, Inc. | Curativo para tratar um local de tecido com pressão negativa, aparelho para tratar um local de tecido com pressão negativa,sistema para tratar um local de tecido, uso de qualquer um dos curativos,aparelhos ou sistemas, método para tratar um ferimento superficial com pressão negativa, método para promover granulação em um ferimento superficial e sistemas, aparelhos e métodos |
| JP7204685B2 (ja) | 2017-06-07 | 2023-01-16 | スリーエム イノベイティブ プロパティズ カンパニー | 陰圧治療での肉芽形成を促進し浸軟を低減させる複合ドレッシング |
| AU2018281102A1 (en) | 2017-06-07 | 2019-12-19 | 3M Innovative Properties Company | Systems, apparatuses, and methods for negative-pressure treatment with reduced tissue in-growth |
| JP2020523073A (ja) | 2017-06-07 | 2020-08-06 | ケーシーアイ ライセンシング インコーポレイテッド | 陰圧治療のための剥がして貼るドレッシング |
| JP7297739B2 (ja) | 2017-10-18 | 2023-06-26 | ライフセル コーポレーション | 脂肪組織製品および製造方法 |
| US11123375B2 (en) | 2017-10-18 | 2021-09-21 | Lifecell Corporation | Methods of treating tissue voids following removal of implantable infusion ports using adipose tissue products |
| JP7463273B2 (ja) | 2017-10-19 | 2024-04-08 | ライフセル コーポレーション | 流動性無細胞組織マトリックス製品および製造方法 |
| US11246994B2 (en) | 2017-10-19 | 2022-02-15 | Lifecell Corporation | Methods for introduction of flowable acellular tissue matrix products into a hand |
| EP3703633B2 (en) | 2017-11-03 | 2024-06-26 | 3M Innovative Properties Company | Extended wear-time dressing |
| EP3710074B1 (en) | 2017-11-16 | 2024-03-20 | ConvaTec Limited | Fluid collection apparatus |
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| EP3976127B1 (en) | 2019-05-30 | 2025-09-24 | LifeCell Corporation | Biologic breast implant |
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| US12178598B2 (en) * | 2019-08-09 | 2024-12-31 | Solventum Intellectual Properties Company | Negative-pressure system incorporating wound diagnostic capabilities |
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| WO2024216269A1 (en) * | 2023-04-13 | 2024-10-17 | The Regents Of The University Of California | Adjustably stable adhesive compositions for medical and non-medical uses, and recycling |
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| CN119587755B (zh) * | 2024-12-10 | 2026-01-30 | 重庆大学 | 一种含有载药acc纳米颗粒的双网络水凝胶及其制备方法和应用 |
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2010
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-
2011
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- 2011-04-06 WO PCT/US2011/031441 patent/WO2011127188A2/en not_active Ceased
- 2011-04-06 JP JP2013503918A patent/JP5988309B2/ja active Active
- 2011-04-06 CA CA2790559A patent/CA2790559A1/en not_active Abandoned
- 2011-04-06 CN CN201510354734.4A patent/CN105126156A/zh active Pending
- 2011-04-06 CN CN201180015381.5A patent/CN103402556B/zh active Active
- 2011-04-06 EP EP11715141.5A patent/EP2555805B1/en active Active
- 2011-04-08 TW TW100112283A patent/TW201141548A/zh unknown
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2016
- 2016-04-22 JP JP2016085736A patent/JP6189473B2/ja not_active Expired - Fee Related
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