JP2013535494A5 - - Google Patents

Download PDF

Info

Publication number
JP2013535494A5
JP2013535494A5 JP2013523598A JP2013523598A JP2013535494A5 JP 2013535494 A5 JP2013535494 A5 JP 2013535494A5 JP 2013523598 A JP2013523598 A JP 2013523598A JP 2013523598 A JP2013523598 A JP 2013523598A JP 2013535494 A5 JP2013535494 A5 JP 2013535494A5
Authority
JP
Japan
Prior art keywords
aqueous suspension
suspension according
amino acids
polypeptide
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013523598A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013535494A (ja
JP5779646B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2011/063720 external-priority patent/WO2012020030A1/en
Publication of JP2013535494A publication Critical patent/JP2013535494A/ja
Publication of JP2013535494A5 publication Critical patent/JP2013535494A5/ja
Application granted granted Critical
Publication of JP5779646B2 publication Critical patent/JP5779646B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2013523598A 2010-08-09 2011-08-09 標的気体封入マイクロベシクル Active JP5779646B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10172318.7 2010-08-09
EP10172318 2010-08-09
PCT/EP2011/063720 WO2012020030A1 (en) 2010-08-09 2011-08-09 Targeted gas-filled microvesicles

Publications (3)

Publication Number Publication Date
JP2013535494A JP2013535494A (ja) 2013-09-12
JP2013535494A5 true JP2013535494A5 (https=) 2014-05-08
JP5779646B2 JP5779646B2 (ja) 2015-09-16

Family

ID=43216307

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013523598A Active JP5779646B2 (ja) 2010-08-09 2011-08-09 標的気体封入マイクロベシクル

Country Status (15)

Country Link
US (2) US9211348B2 (https=)
EP (2) EP2603242B1 (https=)
JP (1) JP5779646B2 (https=)
KR (2) KR101893423B1 (https=)
CN (1) CN103079599B (https=)
AU (1) AU2011288511B2 (https=)
BR (1) BR112013003393B1 (https=)
CA (1) CA2806639C (https=)
DK (2) DK3338807T3 (https=)
ES (2) ES2848721T3 (https=)
HU (2) HUE052894T2 (https=)
IL (1) IL224628A (https=)
SI (2) SI2603242T1 (https=)
WO (1) WO2012020030A1 (https=)
ZA (1) ZA201300660B (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013255952B2 (en) * 2012-04-30 2018-04-12 Ge Healthcare As Method for filling a container with a foamable composition
CN103565745A (zh) * 2012-08-10 2014-02-12 德克萨斯州大学系统董事会 用于治疗中风的神经保护性脂质体组合物和方法
EP2934740B1 (en) * 2012-12-21 2019-12-11 Bracco Suisse SA Gas-filled microvesicles
CA3132914C (en) 2013-03-15 2023-11-07 The Board Of Regents Of The University Of Texas System Liquids rich in noble gas and methods of their preparation and use
WO2015134671A1 (en) 2014-03-04 2015-09-11 Targeson, Inc. Molecular imaging contrast agents and uses thereof
EP3233136B8 (en) 2014-12-18 2019-04-10 Bracco Suisse SA Targeted gas-filled microvesicles formulation
CN107206065A (zh) * 2014-12-22 2017-09-26 博莱科瑞士股份有限公司 用作疫苗的气体填充的微囊
ES3030273T3 (en) * 2015-10-08 2025-06-27 Childrens Medical Ct Corp Compositions and compositions for use in on-demand high-efficiency triggerable anesthesia
IL260957B2 (en) * 2016-02-09 2023-11-01 Bracco Suisse Sa Chimeric, Recombinant Protein Glycoprotein Selectin-P Ligand-1 (PSGL-1) Conjugates, Preparations Containing Them and Uses Thereof
WO2019126182A1 (en) * 2017-12-18 2019-06-27 The University Of Memphis Research Foundation Compositions and methods for the detection and molecular profiling of membrane bound vesicles
WO2020132074A1 (en) 2018-12-18 2020-06-25 The University Of Memphis Research Foundation Compositions and methods for the detection and molecular profiling of membrane bound vesicles
ES2984146T3 (es) 2018-12-21 2024-10-29 Bracco Suisse Sa Microvesículas llenas de gas con ligando

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4276885A (en) 1979-05-04 1981-07-07 Rasor Associates, Inc Ultrasonic image enhancement
IE61591B1 (en) 1987-12-29 1994-11-16 Molecular Biosystems Inc Concentrated stabilized microbubble-type ultrasonic imaging agent and method of production
US5556610A (en) 1992-01-24 1996-09-17 Bracco Research S.A. Gas mixtures useful as ultrasound contrast media, contrast agents containing the media and method
US5445813A (en) 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
IN172208B (https=) 1990-04-02 1993-05-01 Sint Sa
AU636481B2 (en) 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
IL104084A (en) 1992-01-24 1996-09-12 Bracco Int Bv Long-lasting aqueous suspensions of pressure-resistant gas-filled microvesicles their preparation and contrast agents consisting of them
US5843707A (en) 1992-10-23 1998-12-01 Genetics Institute, Inc. Nucleic acid encoding a novel P-selectin ligand protein
EP1550464A1 (en) 1993-07-30 2005-07-06 IMCOR Pharmaceutical Co. Stabilized microbubble composition for ultrasound
US6333021B1 (en) 1994-11-22 2001-12-25 Bracco Research S.A. Microcapsules, method of making and their use
IL116328A (en) 1994-12-16 1999-09-22 Bracco Research Sa Frozen suspension of gas microbubbles in frozen aqueous carrier for use as contrast agent in ultrasonic imaging
WO1997029782A1 (en) 1996-02-19 1997-08-21 Nycomed Imaging A/S Thermally stabilized contrast agent
WO2001075107A2 (en) * 2000-03-31 2001-10-11 Genetics Institute, Llc. Use of p-selectin glycoprotein ligand-1 (psgl-1) and fragments thereof for the inhibition of thrombosis
US20070128117A1 (en) * 2003-02-04 2007-06-07 Bracco International B.V. Ultrasound contrast agents and process for the preparation thereof
JP4670083B2 (ja) * 2003-02-04 2011-04-13 ブラッコ・シュイス・ソシエテ・アノニム 超音波造影剤およびその製造方法
US20060241022A1 (en) 2004-10-06 2006-10-26 Bowen Benjamin P Selectin targeting bioconjugates
JP5242408B2 (ja) 2005-12-09 2013-07-24 ブラッコ・スイス・ソシエテ・アノニム ターゲットベクター・リン脂質コンジュゲート
WO2008131217A1 (en) * 2007-04-20 2008-10-30 Oregon Healty & Science University Ultrasound imaging with targeted microbubbles
WO2009074569A1 (en) * 2007-12-11 2009-06-18 Bracco International Bv Targeting and therapeutic compounds with a polyproline-comprising spacer and gas-filled microvesicles comprising said compounds

Similar Documents

Publication Publication Date Title
JP2013535494A5 (https=)
Zhang et al. Surface engineering of nanomaterials with phospholipid-polyethylene glycol-derived functional conjugates for molecular imaging and targeted therapy
Wang et al. Diagnostic imaging and therapeutic application of nanoparticles targeting the liver
WO2014163558A1 (en) Nanoparticles, composed of sterol and saponin from quillaja saponaria molina process for preparation and use thereof as carrier for amphipatic of hydrphobic molecules in fields of medicine including cancer treatment and food related compounds
JP6347850B2 (ja) 薬物を含有したナノ粒子が結合された二重目的pat/超音波造影剤およびその製造方法
KR20100109896A (ko) 경구 생체이용가능한 지질-기재 구조물
CA2873112A1 (en) Site-specific labeling and targeted delivery of proteins for the treatment of cancer
Wei et al. OFF–ON nanodiamond drug platform for targeted cancer imaging and therapy
Ding et al. Bioconjugated PLGA-4-arm-PEG branched polymeric nanoparticles as novel tumor targeting carriers
EP2552202A1 (en) Methods and compositions for weight loss
WO2014033453A1 (en) Nanoparticle formulation
Yang et al. A new concept of enhancing immuno-chemotherapeutic effects against B16F10 tumor via systemic administration by taking advantages of the limitation of EPR effect
Gui et al. Bone-targeting peptide and RNF146 modified apoptotic extracellular vesicles alleviate osteoporosis
EP2242514A2 (en) Intralymphatic chemotherapy drug carriers
AU2019355926A1 (en) Aromatic ring substituted amphiphilic polymers as drug delivery systems
JP2016094425A5 (https=)
JP2012522841A5 (https=)
RU2015102810A (ru) Функционализированные липосомы, пригодные для доставки биоактивных соединений
Shi et al. An esterase-activatable prodrug formulated liposome strategy: potentiating the anticancer therapeutic efficacy and drug safety
Tian et al. Self‐Assembled Triple‐Targeted Radiosensitizer Enhances Hypoxic Tumor Targeting and Radio‐Immunotherapy Efficacy
KR20200060666A (ko) 플라그 표적화 펩타이드 및 키토산이 결합된 플루로닉 고분자를 포함하는 플라그 표적화 나노전달체
Chowdhury et al. Bile acid linked β-glucan nanoparticles for liver specific oral delivery of biologics
JP6355842B2 (ja) マルチドラッグ送達システム及びその使用
JP2023511073A (ja) 好中球エラスターゼ結合ペプチドおよびその組成物
CN113307824B (zh) 一种双亲性材料及其在制备脂质体中的应用