JP2013535494A5 - - Google Patents
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- Publication number
- JP2013535494A5 JP2013535494A5 JP2013523598A JP2013523598A JP2013535494A5 JP 2013535494 A5 JP2013535494 A5 JP 2013535494A5 JP 2013523598 A JP2013523598 A JP 2013523598A JP 2013523598 A JP2013523598 A JP 2013523598A JP 2013535494 A5 JP2013535494 A5 JP 2013535494A5
- Authority
- JP
- Japan
- Prior art keywords
- aqueous suspension
- suspension according
- amino acids
- polypeptide
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10172318 | 2010-08-09 | ||
| EP10172318.7 | 2010-08-09 | ||
| PCT/EP2011/063720 WO2012020030A1 (en) | 2010-08-09 | 2011-08-09 | Targeted gas-filled microvesicles |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013535494A JP2013535494A (ja) | 2013-09-12 |
| JP2013535494A5 true JP2013535494A5 (enExample) | 2014-05-08 |
| JP5779646B2 JP5779646B2 (ja) | 2015-09-16 |
Family
ID=43216307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013523598A Active JP5779646B2 (ja) | 2010-08-09 | 2011-08-09 | 標的気体封入マイクロベシクル |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US9211348B2 (enExample) |
| EP (2) | EP3338807B1 (enExample) |
| JP (1) | JP5779646B2 (enExample) |
| KR (2) | KR101783653B1 (enExample) |
| CN (1) | CN103079599B (enExample) |
| AU (1) | AU2011288511B2 (enExample) |
| BR (1) | BR112013003393B1 (enExample) |
| CA (1) | CA2806639C (enExample) |
| DK (2) | DK2603242T3 (enExample) |
| ES (2) | ES2848721T3 (enExample) |
| HU (2) | HUE052894T2 (enExample) |
| IL (1) | IL224628A (enExample) |
| SI (2) | SI3338807T1 (enExample) |
| WO (1) | WO2012020030A1 (enExample) |
| ZA (1) | ZA201300660B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX374926B (es) * | 2012-04-30 | 2025-03-06 | Ge Healthcare As | Metodo para llenar un contenedor con una composicion espumable. |
| CN103565745A (zh) | 2012-08-10 | 2014-02-12 | 德克萨斯州大学系统董事会 | 用于治疗中风的神经保护性脂质体组合物和方法 |
| CN105026030B (zh) * | 2012-12-21 | 2017-04-12 | 博莱科瑞士股份有限公司 | 充气微泡 |
| EP4082552B1 (en) | 2013-03-15 | 2026-05-06 | The Board of Regents of the University of Texas System | Liquids rich in noble gas and methods of their preparation and use |
| WO2015134671A1 (en) | 2014-03-04 | 2015-09-11 | Targeson, Inc. | Molecular imaging contrast agents and uses thereof |
| DK3233136T3 (da) * | 2014-12-18 | 2019-05-20 | Bracco Suisse Sa | Formulering med målrettede gasfyldte mikrovesikler |
| EP3236999B1 (en) * | 2014-12-22 | 2019-03-20 | Bracco Suisse SA | Gas-filled microvesicles for use as vaccine |
| ES3030273T3 (en) * | 2015-10-08 | 2025-06-27 | Childrens Medical Ct Corp | Compositions and compositions for use in on-demand high-efficiency triggerable anesthesia |
| BR112018015143A2 (en) | 2016-02-09 | 2018-12-18 | Bracco Suisse Sa | recombinant chimeric protein for selectin targeting |
| US20210190774A1 (en) * | 2017-12-18 | 2021-06-24 | The University Of Memphis Research Foundation | Compositions and methods for the detection and molecular profiling of membrane bound vesicles |
| US11988663B2 (en) | 2018-12-18 | 2024-05-21 | The University Of Memphis Research Foundation | Compositions and methods for the detection and molecular profiling of membrane bound vesicles |
| CA3120179A1 (en) | 2018-12-21 | 2020-06-25 | Bracco Suisse Sa | Gas-filled microvesicles with ligand |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4276885A (en) | 1979-05-04 | 1981-07-07 | Rasor Associates, Inc | Ultrasonic image enhancement |
| IE61591B1 (en) | 1987-12-29 | 1994-11-16 | Molecular Biosystems Inc | Concentrated stabilized microbubble-type ultrasonic imaging agent and method of production |
| US5556610A (en) | 1992-01-24 | 1996-09-17 | Bracco Research S.A. | Gas mixtures useful as ultrasound contrast media, contrast agents containing the media and method |
| IN172208B (enExample) | 1990-04-02 | 1993-05-01 | Sint Sa | |
| US5445813A (en) | 1992-11-02 | 1995-08-29 | Bracco International B.V. | Stable microbubble suspensions as enhancement agents for ultrasound echography |
| AU636481B2 (en) | 1990-05-18 | 1993-04-29 | Bracco International B.V. | Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography |
| IL104084A (en) | 1992-01-24 | 1996-09-12 | Bracco Int Bv | Long-lasting aqueous suspensions of pressure-resistant gas-filled microvesicles their preparation and contrast agents consisting of them |
| US5843707A (en) | 1992-10-23 | 1998-12-01 | Genetics Institute, Inc. | Nucleic acid encoding a novel P-selectin ligand protein |
| EP0711179B2 (en) | 1993-07-30 | 2010-09-01 | IMCOR Pharmaceutical Co. | Stabilized microbubble compositions for ultrasound |
| US6333021B1 (en) | 1994-11-22 | 2001-12-25 | Bracco Research S.A. | Microcapsules, method of making and their use |
| IL116328A (en) | 1994-12-16 | 1999-09-22 | Bracco Research Sa | Frozen suspension of gas microbubbles in frozen aqueous carrier for use as contrast agent in ultrasonic imaging |
| CA2246778A1 (en) | 1996-02-19 | 1997-08-21 | Per Helge Gulliksen | Thermally stabilized contrast agent |
| CA2404572A1 (en) * | 2000-03-31 | 2001-10-11 | Michael J. Eppihimer | Inhibition of thrombosis by treatment with p-selectin antagnosits |
| US20070128117A1 (en) * | 2003-02-04 | 2007-06-07 | Bracco International B.V. | Ultrasound contrast agents and process for the preparation thereof |
| WO2004069284A2 (en) | 2003-02-04 | 2004-08-19 | Bracco International B.V. | Ultrasound contrast agents and process for the preparation thereof |
| US20060241022A1 (en) | 2004-10-06 | 2006-10-26 | Bowen Benjamin P | Selectin targeting bioconjugates |
| CN101374955B (zh) | 2005-12-09 | 2013-03-27 | 布拉科瑞士有限公司 | 靶向载体-磷脂缀合物 |
| CA2684752A1 (en) * | 2007-04-20 | 2008-10-30 | Oregon Health & Science University | Ultrasound imaging with targeted microbubbles |
| WO2009074569A1 (en) * | 2007-12-11 | 2009-06-18 | Bracco International Bv | Targeting and therapeutic compounds with a polyproline-comprising spacer and gas-filled microvesicles comprising said compounds |
-
2011
- 2011-08-09 CN CN201180039277.XA patent/CN103079599B/zh active Active
- 2011-08-09 JP JP2013523598A patent/JP5779646B2/ja active Active
- 2011-08-09 HU HUE18156131A patent/HUE052894T2/hu unknown
- 2011-08-09 ES ES18156131T patent/ES2848721T3/es active Active
- 2011-08-09 KR KR1020137005859A patent/KR101783653B1/ko active Active
- 2011-08-09 SI SI201131960T patent/SI3338807T1/sl unknown
- 2011-08-09 CA CA2806639A patent/CA2806639C/en active Active
- 2011-08-09 EP EP18156131.7A patent/EP3338807B1/en active Active
- 2011-08-09 EP EP11743811.9A patent/EP2603242B1/en active Active
- 2011-08-09 HU HUE11743811A patent/HUE037768T2/hu unknown
- 2011-08-09 SI SI201131501T patent/SI2603242T1/sl unknown
- 2011-08-09 ES ES11743811.9T patent/ES2673277T3/es active Active
- 2011-08-09 AU AU2011288511A patent/AU2011288511B2/en active Active
- 2011-08-09 DK DK11743811.9T patent/DK2603242T3/en active
- 2011-08-09 DK DK18156131.7T patent/DK3338807T3/da active
- 2011-08-09 US US13/814,329 patent/US9211348B2/en active Active
- 2011-08-09 BR BR112013003393-2A patent/BR112013003393B1/pt active IP Right Grant
- 2011-08-09 KR KR1020177027001A patent/KR101893423B1/ko active Active
- 2011-08-09 WO PCT/EP2011/063720 patent/WO2012020030A1/en not_active Ceased
-
2013
- 2013-01-24 ZA ZA2013/00660A patent/ZA201300660B/en unknown
- 2013-02-07 IL IL224628A patent/IL224628A/en active IP Right Grant
-
2015
- 2015-10-30 US US14/927,865 patent/US9333273B2/en active Active
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