JP2013534140A5 - - Google Patents
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- JP2013534140A5 JP2013534140A5 JP2013523311A JP2013523311A JP2013534140A5 JP 2013534140 A5 JP2013534140 A5 JP 2013534140A5 JP 2013523311 A JP2013523311 A JP 2013523311A JP 2013523311 A JP2013523311 A JP 2013523311A JP 2013534140 A5 JP2013534140 A5 JP 2013534140A5
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- JP
- Japan
- Prior art keywords
- cells
- immortalized
- cell
- reprogramming
- inhibitors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37061510P | 2010-08-04 | 2010-08-04 | |
| US61/370,615 | 2010-08-04 | ||
| US201161441885P | 2011-02-11 | 2011-02-11 | |
| US61/441,885 | 2011-02-11 | ||
| PCT/US2011/046452 WO2012018933A2 (en) | 2010-08-04 | 2011-08-03 | Reprogramming immortalized b cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015248381A Division JP2016039828A (ja) | 2010-08-04 | 2015-12-21 | 不死化b細胞のリプログラミング |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013534140A JP2013534140A (ja) | 2013-09-02 |
| JP2013534140A5 true JP2013534140A5 (enExample) | 2014-08-21 |
| JP5936218B2 JP5936218B2 (ja) | 2016-06-22 |
Family
ID=45560057
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013523311A Active JP5936218B2 (ja) | 2010-08-04 | 2011-08-03 | 不死化b細胞のリプログラミング |
| JP2015248381A Pending JP2016039828A (ja) | 2010-08-04 | 2015-12-21 | 不死化b細胞のリプログラミング |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015248381A Pending JP2016039828A (ja) | 2010-08-04 | 2015-12-21 | 不死化b細胞のリプログラミング |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US8765470B2 (enExample) |
| EP (1) | EP2601289B1 (enExample) |
| JP (2) | JP5936218B2 (enExample) |
| CA (1) | CA2806858C (enExample) |
| WO (1) | WO2012018933A2 (enExample) |
Families Citing this family (54)
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| CN103087991B (zh) | 2009-06-05 | 2018-06-12 | 富士胶片细胞动力公司 | 重编程t细胞和造血细胞的方法 |
| WO2011016588A1 (en) | 2009-08-07 | 2011-02-10 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| CN106893692B (zh) * | 2010-12-22 | 2021-11-26 | 菲特治疗公司 | 用于单细胞分选与增强ipsc重新编程的细胞培养平台 |
| JP2014520551A (ja) * | 2011-07-11 | 2014-08-25 | セルラー ダイナミクス インターナショナル, インコーポレイテッド | 細胞のリプログラミング方法およびゲノムの改変方法 |
| CN102604894B (zh) * | 2012-02-29 | 2014-07-30 | 中国科学院广州生物医药与健康研究院 | 用于制备神经干细胞的培养基及其用途 |
| EP2853592B1 (en) * | 2012-05-23 | 2019-02-20 | Kyoto University | Highly efficient method for establishing artificial pluripotent stem cell |
| EP2971039B1 (en) | 2013-03-14 | 2020-01-01 | Immusoft Corporation | Methods for in vitro memory b cell differentiation and transduction with vsv-g pseudotyped viral vectors |
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| SG10201807292YA (en) | 2014-03-04 | 2018-09-27 | Fate Therapeutics Inc | Improved reprogramming methods and cell culture platforms |
| CN105154386B (zh) * | 2014-05-30 | 2018-04-24 | 中国人民解放军第二军医大学东方肝胆外科医院 | 人肝细胞长期维持和增殖传代培养的专用培养基和培养方法 |
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| US20190060371A1 (en) * | 2016-03-02 | 2019-02-28 | Frequency Therapeutics, Inc. | Methods for controlled proliferation of vestibular stem cells / generating inner ear hair cells using wnt and tgfbeta-inhibition |
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| WO2017217756A2 (ko) * | 2016-06-15 | 2017-12-21 | 한국생명공학연구원 | 자살유전자를 포함한 에피솜 벡터 및 이를 이용한 리프로그래밍 방법 |
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| US10221395B2 (en) | 2016-06-16 | 2019-03-05 | Cedars-Sinai Medical Center | Efficient method for reprogramming blood to induced pluripotent stem cells |
| CN108148808B (zh) * | 2016-12-05 | 2020-12-11 | 同济大学 | 有助于诱导生成神经前体细胞的诱导培养基 |
| US11624056B2 (en) | 2017-01-19 | 2023-04-11 | Yipcell Inc. | Method for producing cartilage cells induced to be differentiated from stem cells |
| US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
| CN110621323B (zh) * | 2017-05-02 | 2022-10-14 | 田边刚士 | 医药品组合物及化妆品组合物 |
| WO2018232079A1 (en) | 2017-06-14 | 2018-12-20 | Daley George Q | Hematopoietic stem and progenitor cells derived from hemogenic endothelial cells by episomal plasmid gene transfer |
| CA3078734A1 (en) * | 2017-10-11 | 2019-04-18 | Fate Therapeutics, Inc. | Cellular reprogramming using temporal and transient plasmid vector expression system |
| WO2019106163A1 (en) * | 2017-12-01 | 2019-06-06 | Cellectis | Reprogramming of genetically engineered primary immune cells |
| JP7473209B2 (ja) * | 2018-01-29 | 2024-04-23 | 中国科学院動物研究所 | 細胞誘導の方法 |
| WO2020037326A1 (en) | 2018-08-17 | 2020-02-20 | Frequency Therapeutics, Inc. | Compositions and methods for generating hair cells by downregulating foxo |
| US11162071B2 (en) | 2018-08-17 | 2021-11-02 | Frequency Therapeutics, Inc. | Compositions and methods for generating hair cells by upregulating JAG-1 |
| WO2020074925A2 (en) * | 2018-10-12 | 2020-04-16 | Reneuron Limited | Induced pluripotent cell comprising a controllable transgene for conditional immortalisation |
| EP3946470A4 (en) * | 2019-04-05 | 2023-05-31 | Earli Inc. | IMPROVED METHODS AND COMPOSITIONS FOR SYNTHETIC BIOMARKERS |
| MX2022008648A (es) | 2020-01-23 | 2022-12-15 | The Children´S Medical Center Corp | Diferenciacion de celulas t sin estroma a partir de celulas madre pluripotentes humanas. |
| BR112022018092A2 (pt) | 2020-03-11 | 2022-11-22 | Bit Bio Ltd | Método de gerar células hepáticas |
| AU2021392032A1 (en) | 2020-12-03 | 2023-06-22 | Century Therapeutics, Inc. | Genetically engineered cells and uses thereof |
| US11661459B2 (en) | 2020-12-03 | 2023-05-30 | Century Therapeutics, Inc. | Artificial cell death polypeptide for chimeric antigen receptor and uses thereof |
| JP2024519515A (ja) | 2021-04-07 | 2024-05-15 | センチュリー セラピューティクス,インコーポレイテッド | 人工多能性幹細胞からガンマ-デルタt細胞を生成するための組成物および方法 |
| CN117441010A (zh) | 2021-04-07 | 2024-01-23 | 世纪治疗股份有限公司 | 从诱导多能干细胞产生α-βT细胞的组合物和方法 |
| WO2022216524A1 (en) | 2021-04-07 | 2022-10-13 | Century Therapeutics, Inc. | Combined artificial cell death/reporter system polypeptide for chimeric antigen receptor cell and uses thereof |
| CA3210702A1 (en) | 2021-04-07 | 2022-10-13 | Century Therapeutics, Inc. | Gene transfer vectors and methods of engineering cells |
| AU2022369304A1 (en) * | 2021-10-20 | 2024-04-11 | Exir, Inc. | Compositions and methods for using individualized genome assemblies and induced pluripotent stem cell lines of nonhuman primates for pre-clinical evaluation |
| EP4456912A1 (en) | 2021-12-29 | 2024-11-06 | Century Therapeutics, Inc. | Genetically engineered cells having anti-cd19 / anti-cd22 chimeric antigen receptors, and uses thereof |
| CN119365492A (zh) | 2022-05-04 | 2025-01-24 | 世纪治疗股份有限公司 | 用hla-e和hla-g转基因工程化的细胞 |
| US20250090582A1 (en) | 2022-06-08 | 2025-03-20 | Century Therapeutics, Inc. | Genetically engineered cells having anti-cd133 / anti-egfr chimeric antigen receptors, and uses thereof |
| WO2023240169A1 (en) | 2022-06-08 | 2023-12-14 | Century Therapeutics, Inc. | Immunoeffector cells derived from induced pluripotent stem cells genetically engineered with membrane bound il12 and uses thereof |
| CN119630695A (zh) | 2022-06-08 | 2025-03-14 | 世纪治疗股份有限公司 | 表达cd16变体和nkg2d的遗传工程化细胞及其用途 |
| WO2024102838A1 (en) | 2022-11-09 | 2024-05-16 | Century Therapeutics, Inc. | Engineered interleukin-7 receptors and uses thereof |
| WO2024103017A2 (en) | 2022-11-10 | 2024-05-16 | Century Therapeutics, Inc. | Genetically engineered cells having anti-nectin4 chimeric antigen receptors, and uses thereof |
| WO2025101938A2 (en) | 2023-11-10 | 2025-05-15 | Century Therapeutics, Inc. | Genetically engineered cells having multi-transmembrane domain chimeric antigen receptors utilizing g protein-coupled receptor scaffolds, and uses thereof |
| WO2025106626A1 (en) | 2023-11-15 | 2025-05-22 | Century Therapeutics, Inc. | Genetically engineered cells expressing c-x-c chemokine receptor type 4, and uses thereof |
| WO2025207798A1 (en) | 2024-03-26 | 2025-10-02 | Century Therapeutics, Inc. | Genetically engineered cells having anti-cd123 chimeric antigen receptors, and uses thereof |
| WO2025207795A1 (en) | 2024-03-26 | 2025-10-02 | Juno Therapeutics, Inc. | Genetically engineered cells having anti-cd33 / anti-cd123 chimeric antigen receptors, and uses thereof |
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-
2011
- 2011-08-03 US US13/197,529 patent/US8765470B2/en active Active
- 2011-08-03 EP EP11815273.5A patent/EP2601289B1/en active Active
- 2011-08-03 CA CA2806858A patent/CA2806858C/en active Active
- 2011-08-03 WO PCT/US2011/046452 patent/WO2012018933A2/en not_active Ceased
- 2011-08-03 JP JP2013523311A patent/JP5936218B2/ja active Active
-
2014
- 2014-05-21 US US14/284,283 patent/US20140349397A1/en not_active Abandoned
-
2015
- 2015-12-21 JP JP2015248381A patent/JP2016039828A/ja active Pending
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