JP2013534140A5 - - Google Patents
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- JP2013534140A5 JP2013534140A5 JP2013523311A JP2013523311A JP2013534140A5 JP 2013534140 A5 JP2013534140 A5 JP 2013534140A5 JP 2013523311 A JP2013523311 A JP 2013523311A JP 2013523311 A JP2013523311 A JP 2013523311A JP 2013534140 A5 JP2013534140 A5 JP 2013534140A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- immortalized
- cell
- reprogramming
- inhibitors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37061510P | 2010-08-04 | 2010-08-04 | |
| US61/370,615 | 2010-08-04 | ||
| US201161441885P | 2011-02-11 | 2011-02-11 | |
| US61/441,885 | 2011-02-11 | ||
| PCT/US2011/046452 WO2012018933A2 (en) | 2010-08-04 | 2011-08-03 | Reprogramming immortalized b cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015248381A Division JP2016039828A (ja) | 2010-08-04 | 2015-12-21 | 不死化ｂ細胞のリプログラミング |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013534140A JP2013534140A (ja) | 2013-09-02 |
| JP2013534140A5 true JP2013534140A5 (enExample) | 2014-08-21 |
| JP5936218B2 JP5936218B2 (ja) | 2016-06-22 |
Family
ID=45560057
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013523311A Active JP5936218B2 (ja) | 2010-08-04 | 2011-08-03 | 不死化ｂ細胞のリプログラミング |
| JP2015248381A Pending JP2016039828A (ja) | 2010-08-04 | 2015-12-21 | 不死化ｂ細胞のリプログラミング |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015248381A Pending JP2016039828A (ja) | 2010-08-04 | 2015-12-21 | 不死化ｂ細胞のリプログラミング |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US8765470B2 (enExample) |
| EP (1) | EP2601289B1 (enExample) |
| JP (2) | JP5936218B2 (enExample) |
| CA (1) | CA2806858C (enExample) |
| WO (1) | WO2012018933A2 (enExample) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105925535A (zh) | 2009-06-05 | 2016-09-07 | 细胞动力国际有限公司 | 重编程t细胞和造血细胞的方法 |
| US8900871B2 (en) | 2009-08-07 | 2014-12-02 | Kyoto University | Method of producing induced pluripotent stem cells using inhibitors of P53 |
| US9732319B2 (en) | 2010-12-22 | 2017-08-15 | Fate Therapeutics, Inc. | Cell culture platform for single cell sorting and enhanced reprogramming of iPSCs |
| WO2013009825A1 (en) * | 2011-07-11 | 2013-01-17 | Cellular Dynamics International, Inc. | Methods for cell reprogramming and genome engineering |
| CN102604894B (zh) * | 2012-02-29 | 2014-07-30 | 中国科学院广州生物医药与健康研究院 | 用于制备神经干细胞的培养基及其用途 |
| CA2874259C (en) * | 2012-05-23 | 2021-02-09 | Kyoto University | Highly efficient method for establishing induced pluripotent stem cell |
| ES2786253T3 (es) | 2013-03-14 | 2020-10-09 | Immusoft Corp | Métodos para la diferenciación y transducción in vitro de células b de memoria con vectores virales pseudotipados vsv-g |
| US20160115455A1 (en) * | 2013-05-17 | 2016-04-28 | The Broad Institute, Inc. | Reprogrammed cells and methods of production and use thereof |
| US10738323B2 (en) | 2013-07-12 | 2020-08-11 | Cedars-Sinai Medical Center | Generation of induced pluripotent stem cells from normal human mammary epithelial cells |
| CN120536341A (zh) | 2014-03-04 | 2025-08-26 | 菲特治疗公司 | 改良的重编程方法和细胞培养平台 |
| CN105154386B (zh) * | 2014-05-30 | 2018-04-24 | 中国人民解放军第二军医大学东方肝胆外科医院 | 人肝细胞长期维持和增殖传代培养的专用培养基和培养方法 |
| EP4177336A1 (en) * | 2014-12-19 | 2023-05-10 | Immusoft Corporation | B cells for in vivo delivery of therapeutic agents |
| KR101768581B1 (ko) * | 2015-08-13 | 2017-08-17 | 전북대학교 산학협력단 | 자발적 불멸화된 체세포의 단일 세포로부터 리프로그래밍 세포주의 제조방법 |
| CN117737124A (zh) | 2015-10-16 | 2024-03-22 | 菲特治疗公司 | 用于诱导和维护基态多能性的平台 |
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| US10201540B2 (en) | 2016-03-02 | 2019-02-12 | Frequency Therapeutics, Inc. | Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using GSK3 inhibitors: I |
| US20190060371A1 (en) * | 2016-03-02 | 2019-02-28 | Frequency Therapeutics, Inc. | Methods for controlled proliferation of vestibular stem cells / generating inner ear hair cells using wnt and tgfbeta-inhibition |
| US10213511B2 (en) | 2016-03-02 | 2019-02-26 | Frequency Therapeutics, Inc. | Thermoreversible compositions for administration of therapeutic agents |
| US11185555B2 (en) | 2016-04-11 | 2021-11-30 | Noah James Harrison | Method to kill pathogenic microbes in a patient |
| WO2017217756A2 (ko) * | 2016-06-15 | 2017-12-21 | 한국생명공학연구원 | 자살유전자를 포함한 에피솜 벡터 및 이를 이용한 리프로그래밍 방법 |
| US10221395B2 (en) | 2016-06-16 | 2019-03-05 | Cedars-Sinai Medical Center | Efficient method for reprogramming blood to induced pluripotent stem cells |
| US11572545B2 (en) | 2016-06-16 | 2023-02-07 | Cedars-Sinai Medical Center | Efficient method for reprogramming blood to induced pluripotent stem cells |
| JP7215994B2 (ja) | 2016-09-06 | 2023-01-31 | ザ チルドレンズ メディカル センター コーポレーション | 人工多能性幹細胞由来の免疫細胞 |
| CN108148808B (zh) * | 2016-12-05 | 2020-12-11 | 同济大学 | 有助于诱导生成神经前体细胞的诱导培养基 |
| WO2018135902A1 (ko) * | 2017-01-19 | 2018-07-26 | 가톨릭대학교 산학협력단 | 줄기 세포로부터 분화 유도된 연골세포의 제조방법 |
| US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
| JP6647545B2 (ja) * | 2017-05-02 | 2020-02-14 | 剛士 田邊 | 医薬品組成物及び化粧品組成物 |
| US11572544B2 (en) | 2017-06-14 | 2023-02-07 | The Children's Medical Center Corporation | Hematopoietic stem and progenitor cells derived from hemogenic endothelial cells by episomal plasmid gene transfer |
| US12247226B2 (en) * | 2017-10-11 | 2025-03-11 | Fate Therapeutics, Inc. | Cellular reprogramming using temporal and transient plasmid vector expression system |
| WO2019106163A1 (en) * | 2017-12-01 | 2019-06-06 | Cellectis | Reprogramming of genetically engineered primary immune cells |
| EP3747991A4 (en) * | 2018-01-29 | 2022-01-19 | Institute Of Zoology, Chinese Academy Of Sciences | METHOD OF INDUCING CELLS |
| WO2020037323A1 (en) | 2018-08-17 | 2020-02-20 | Frequency Therapeutics, Inc. | Compositions and methods for generating hair cells by upregulating jag-1 |
| WO2020037326A1 (en) | 2018-08-17 | 2020-02-20 | Frequency Therapeutics, Inc. | Compositions and methods for generating hair cells by downregulating foxo |
| WO2020074925A2 (en) * | 2018-10-12 | 2020-04-16 | Reneuron Limited | Induced pluripotent cell comprising a controllable transgene for conditional immortalisation |
| EP3946470A4 (en) * | 2019-04-05 | 2023-05-31 | Earli Inc. | IMPROVED METHODS AND COMPOSITIONS FOR SYNTHETIC BIOMARKERS |
| US12582726B1 (en) | 2019-04-05 | 2026-03-24 | Earli Inc. | Synthetic cancer-specific promoters |
| KR20220130158A (ko) | 2020-01-23 | 2022-09-26 | 더 칠드런스 메디칼 센터 코포레이션 | 인간 만능 줄기 세포로부터의 무-간질 t 세포 분화 |
| KR20230010625A (ko) | 2020-03-11 | 2023-01-19 | 비트 바이오 리미티드 | 간 세포 생성 방법 |
| US11661459B2 (en) | 2020-12-03 | 2023-05-30 | Century Therapeutics, Inc. | Artificial cell death polypeptide for chimeric antigen receptor and uses thereof |
| IL303269A (en) | 2020-12-03 | 2023-07-01 | Century Therapeutics Inc | Genetically engineered cells and uses thereof |
| AU2022252997A1 (en) | 2021-04-07 | 2023-09-28 | Century Therapeutics, Inc. | Compositions and methods for generating gamma-delta t cells from induced pluripotent stem cells |
| CA3210702A1 (en) | 2021-04-07 | 2022-10-13 | Century Therapeutics, Inc. | Gene transfer vectors and methods of engineering cells |
| AU2022253223A1 (en) | 2021-04-07 | 2023-09-28 | Century Therapeutics, Inc. | Combined artificial cell death/reporter system polypeptide for chimeric antigen receptor cell and uses thereof |
| CA3214473A1 (en) | 2021-04-07 | 2022-10-13 | Century Therapeutics, Inc. | Compositions and methods for generating alpha-beta t cells from induced pluripotent stem cells |
| CA3233140A1 (en) * | 2021-10-20 | 2023-04-27 | Morteza ROODGAR | Compositions and methods for using individualized genome assemblies and induced pluripotent stem cell lines of nonhuman primates for pre-clinical evaluation |
| WO2023129937A1 (en) | 2021-12-29 | 2023-07-06 | Century Therapeutics, Inc. | Genetically engineered cells having anti-cd19 / anti-cd22 chimeric antigen receptors, and uses thereof |
| JP2025515095A (ja) | 2022-05-04 | 2025-05-13 | センチュリー セラピューティクス，インコーポレイテッド | Ｈｌａ－ｅおよびｈｌａ－ｇ導入遺伝子を用いて操作された細胞 |
| EP4536814A1 (en) | 2022-06-08 | 2025-04-16 | Century Therapeutics, Inc. | Immunoeffector cells derived from induced pluripotent stem cells genetically engineered with membrane bound il12 and uses thereof |
| US20250090582A1 (en) | 2022-06-08 | 2025-03-20 | Century Therapeutics, Inc. | Genetically engineered cells having anti-cd133 / anti-egfr chimeric antigen receptors, and uses thereof |
| CN119630695A (zh) | 2022-06-08 | 2025-03-14 | 世纪治疗股份有限公司 | 表达cd16变体和nkg2d的遗传工程化细胞及其用途 |
| WO2024102838A1 (en) | 2022-11-09 | 2024-05-16 | Century Therapeutics, Inc. | Engineered interleukin-7 receptors and uses thereof |
| CN120435498A (zh) | 2022-11-10 | 2025-08-05 | 世纪治疗股份有限公司 | 具有抗-nectin4嵌合抗原受体的基因工程化细胞及其用途 |
| WO2025101938A2 (en) | 2023-11-10 | 2025-05-15 | Century Therapeutics, Inc. | Genetically engineered cells having multi-transmembrane domain chimeric antigen receptors utilizing g protein-coupled receptor scaffolds, and uses thereof |
| WO2025106626A1 (en) | 2023-11-15 | 2025-05-22 | Century Therapeutics, Inc. | Genetically engineered cells expressing c-x-c chemokine receptor type 4, and uses thereof |
| WO2025207798A1 (en) | 2024-03-26 | 2025-10-02 | Century Therapeutics, Inc. | Genetically engineered cells having anti-cd123 chimeric antigen receptors, and uses thereof |
| WO2025207795A1 (en) | 2024-03-26 | 2025-10-02 | Juno Therapeutics, Inc. | Genetically engineered cells having anti-cd33 / anti-cd123 chimeric antigen receptors, and uses thereof |
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| KR101775926B1 (ko) | 2009-11-04 | 2017-09-07 | 셀룰러 다이내믹스 인터내셔널, 인코포레이티드 | 화학 물질을 이용한 에피솜 재프로그래밍 |
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| US20140127814A1 (en) * | 2010-08-10 | 2014-05-08 | Srinivasan Chandrasegaran | Generation and use of pluripotent stem cells |
-
2011
- 2011-08-03 EP EP11815273.5A patent/EP2601289B1/en active Active
- 2011-08-03 CA CA2806858A patent/CA2806858C/en active Active
- 2011-08-03 JP JP2013523311A patent/JP5936218B2/ja active Active
- 2011-08-03 WO PCT/US2011/046452 patent/WO2012018933A2/en not_active Ceased
- 2011-08-03 US US13/197,529 patent/US8765470B2/en active Active
-
2014
- 2014-05-21 US US14/284,283 patent/US20140349397A1/en not_active Abandoned
-
2015
- 2015-12-21 JP JP2015248381A patent/JP2016039828A/ja active Pending
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