JP2013531006A5 - - Google Patents
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- Publication number
- JP2013531006A5 JP2013531006A5 JP2013517611A JP2013517611A JP2013531006A5 JP 2013531006 A5 JP2013531006 A5 JP 2013531006A5 JP 2013517611 A JP2013517611 A JP 2013517611A JP 2013517611 A JP2013517611 A JP 2013517611A JP 2013531006 A5 JP2013531006 A5 JP 2013531006A5
- Authority
- JP
- Japan
- Prior art keywords
- depression
- disorder
- alkyl
- pharmaceutically acceptable
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36250510P | 2010-07-08 | 2010-07-08 | |
| US61/362,505 | 2010-07-08 | ||
| PCT/IB2011/052686 WO2012004698A1 (en) | 2010-07-08 | 2011-06-20 | Piperidinyl pyrimidine amides as kv7 potassium channel openers |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013531006A JP2013531006A (ja) | 2013-08-01 |
| JP2013531006A5 true JP2013531006A5 (enExample) | 2014-06-05 |
| JP5763758B2 JP5763758B2 (ja) | 2015-08-12 |
Family
ID=44487037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013517611A Expired - Fee Related JP5763758B2 (ja) | 2010-07-08 | 2011-06-20 | Ｋｖ７カリウムチャネル開口薬としてのピペリジニルピリミジンアミド |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8883812B2 (enExample) |
| EP (1) | EP2590961A1 (enExample) |
| JP (1) | JP5763758B2 (enExample) |
| KR (1) | KR101449348B1 (enExample) |
| CN (1) | CN102971307A (enExample) |
| AU (1) | AU2011275393B2 (enExample) |
| CA (1) | CA2804165C (enExample) |
| MX (1) | MX2013000138A (enExample) |
| SG (1) | SG186409A1 (enExample) |
| WO (1) | WO2012004698A1 (enExample) |
| ZA (1) | ZA201300499B (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013067591A1 (en) * | 2011-11-10 | 2013-05-16 | Relevare Australia Pty Ltd | Topical formulations for pain management |
| US10154988B2 (en) | 2012-11-14 | 2018-12-18 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| WO2014145852A2 (en) | 2013-03-15 | 2014-09-18 | Knopp Biosciences Llc | Imidazo(4,5-b) pyridin-2-yl amides as kv7 channel activators |
| ES2749103T3 (es) * | 2014-09-12 | 2020-03-19 | Knopp Biosciences Llc | Benzoimidazol-1,2-ilamidas como activadores del canal Kv7 |
| ES3032221T3 (en) * | 2018-02-20 | 2025-07-16 | H Lundbeck As | Alcohol derivatives as kv7 potassium channel openers |
| CN119118926A (zh) | 2018-03-19 | 2024-12-13 | 诺普生物科学有限责任公司 | Kv7通道激活剂组合物和使用方法 |
| AR119521A1 (es) * | 2019-08-02 | 2021-12-22 | H Lundbeck As | DERIVADOS DE ALCOHOL COMO ABRIDORES DEL CANAL DE POTASIO Kv7 |
| IL328371A (en) * | 2019-09-17 | 2026-07-01 | Knopp Biosciences Llc | Usage methods for KV7 channel operators |
| WO2021119018A1 (en) * | 2019-12-09 | 2021-06-17 | The Board Of Trustees Of The Leland Stanford Junior University | A method to improve sleep quality in the elderly by controlling excitability of hypocretin neurons |
| WO2021211867A1 (en) * | 2020-04-16 | 2021-10-21 | Attune Neurosciences, Inc. | Kv7 modulators for treating sleep or anxiety disorders |
| KR20230079055A (ko) * | 2020-08-28 | 2023-06-05 | 화이자 인코포레이티드 | 호흡기 병태 모니터링 및 케어를 위한 컴퓨터화된 의사결정 지원 툴 및 의료 디바이스 |
| GB202306914D0 (en) * | 2023-05-10 | 2023-06-21 | Sania Rx Ltd | Method |
| GB2703561A (en) * | 2024-11-08 | 2026-08-05 | Sania Tx Ltd | Method |
| WO2026099781A1 (en) * | 2024-11-08 | 2026-05-15 | Sania Tx Ltd | Method |
| CN119661413B (zh) * | 2024-12-28 | 2025-06-24 | 齐鲁医药学院 | Kv7钾离子通道开放剂及其制备方法和应用 |
| WO2026159425A1 (en) * | 2025-01-22 | 2026-07-30 | Climb Bio, Inc. | Azetidin derivatives as potassium chanel inhibitors |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ20032233A3 (cs) * | 2001-02-20 | 2004-12-15 | Bristol-Myers Squibb Company | Derivát 2,4-disubstituovaného pyrimidin-5-karboxamidu jako modulátor draslíkového kanálku KCNQ |
| TWI349666B (en) | 2004-03-12 | 2011-10-01 | Lundbeck & Co As H | Substituted morpholine and thiomorpholine derivatives |
| US7091202B2 (en) * | 2004-09-15 | 2006-08-15 | Bristol-Myers Squibb Company | 4-arylspirocycloalkyl-2-aminopyrimidine carboxamide KCNQ potassium channel modulators |
| US20080261918A1 (en) * | 2004-12-17 | 2008-10-23 | Graham Andrew Showell | Silicon Compounds and Their Use |
| US7322249B2 (en) | 2005-07-07 | 2008-01-29 | Delphi Technologies, Inc. | Mounting for a probe sensor |
| EP1937653A1 (en) * | 2005-09-09 | 2008-07-02 | H.Lundbeck A/S | Pyrimidine derivatives and their use as kcnq potassium channels openers |
| US7683058B2 (en) * | 2005-09-09 | 2010-03-23 | H. Lundbeck A/S | Substituted pyrimidine derivatives |
| US20090118285A1 (en) | 2006-02-07 | 2009-05-07 | H. Lundbeck A/S | Use of kcnq-openers for treating or reducing the symptoms of schizophrenia |
| NZ575652A (en) | 2006-08-23 | 2011-08-26 | Valeant Pharmaceuticals Int | Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators |
| US8367684B2 (en) * | 2007-06-13 | 2013-02-05 | Valeant Pharmaceuticals International | Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators |
| CN101790374A (zh) | 2007-08-01 | 2010-07-28 | H.隆德贝克有限公司 | Kcnq钾通道开放剂用于减轻多巴胺能系统受到干扰的障碍或病症的症状或治疗这种障碍或病症的用途 |
-
2011
- 2011-06-20 US US13/808,355 patent/US8883812B2/en not_active Expired - Fee Related
- 2011-06-20 KR KR1020137000377A patent/KR101449348B1/ko not_active Expired - Fee Related
- 2011-06-20 JP JP2013517611A patent/JP5763758B2/ja not_active Expired - Fee Related
- 2011-06-20 CN CN2011800337518A patent/CN102971307A/zh active Pending
- 2011-06-20 SG SG2012093761A patent/SG186409A1/en unknown
- 2011-06-20 EP EP11738482.6A patent/EP2590961A1/en not_active Withdrawn
- 2011-06-20 WO PCT/IB2011/052686 patent/WO2012004698A1/en not_active Ceased
- 2011-06-20 AU AU2011275393A patent/AU2011275393B2/en not_active Ceased
- 2011-06-20 MX MX2013000138A patent/MX2013000138A/es active IP Right Grant
- 2011-06-20 CA CA2804165A patent/CA2804165C/en not_active Expired - Fee Related
-
2013
- 2013-01-18 ZA ZA2013/00499A patent/ZA201300499B/en unknown
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